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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2020
  2. Published

    Ribavirin inhibition of cell-culture infectious hepatitis C genotype 1-3 viruses is strain-dependent

    Mejer, N., Galli, A., Ramirez, S., Fahnøe, U., Benfield, T. & Bukh, J., 15 Jan 2020, In : Virology. 540, p. 132-140 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2019
  4. E-pub ahead of print
  5. E-pub ahead of print

    Antibody Responses to Immunization With HCV Envelope Glycoproteins as a Baseline for B cell-Based Vaccine Development

    Chen, F., Nagy, K., Chavez, D., Willis, S., McBride, R., Giang, E., Honda, A., Bukh, J., Ordoukhanian, P., Zhu, J., Frey, S., Lanford, R. & Law, M., 3 Dec 2019, In : Gastroenterology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Genome Sequence of an Unknown Subtype of Hepatitis C Virus Genotype 6: Another Piece for the Taxonomic Puzzle

    Pedersen, M. S., Mollerup, S., Nielsen, L. G., Jenssen, H., Bukh, J. & Schønning, K., 17 Oct 2019, In : Microbiology Resource Announcements. 8, 42, e01030-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Virus Adaptation and Selection Following Challenge of Animals Vaccinated against Classical Swine Fever Virus

    Fahnøe, U., Pedersen, A. G., Johnston, C. M., Orton, R. J., Höper, D., Beer, M., Bukh, J., Belsham, G. J. & Rasmussen, T. B., 10 Oct 2019, In : Viruses. 11, 10

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    HCV p7 as a novel vaccine-target inducing multifunctional CD4+ and CD8+ T-cells targeting liver cells expressing the viral antigen

    Filskov, J., Andersen, P., Agger, E. M. & Bukh, J., 1 Oct 2019, In : Scientific Reports. 9, 14085.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Replicons of a rodent hepatitis C model virus permit selection of highly permissive cells

    Wolfisberg, R., Holmbeck, K., Nielsen, L., Kapoor, A., Rice, C. M., Bukh, J. & Scheel, T. K. H., 1 Oct 2019, In : Journal of Virology. 93, 19

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Evolutionary Pathways to Persistence of Highly Fit and Resistant Hepatitis C Virus Protease Inhibitor Escape Variants

    Jensen, S. B., Fahnøe, U., Pham, L. V., Serre, S., Tang, Q., Ghanem, L., Pedersen, M. S., Ramirez, S., Humes, D., Pihl, A. F., Filskov, J., Sølund, C. S., Dietz, J., Fourati, S., Pawlotsky, J-M., Sarrazin, C., Weis, N., Schønning, K., Krarup, H., Bukh, J. & Gottwein, J. M., Sep 2019, In : Hepatology (Baltimore, Md.). 70, 3, p. 771-787 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published
  12. Published

    Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis C virus infections uncover molecular determinants for E2 targeting and vaccine design

    Keck, Z-Y., Pierce, B. G., Lau, P., Lu, J., Wang, Y., Underwood, A., Bull, R. A., Prentoe, J., Velázquez-Moctezuma, R., Walker, M. R., Luciani, F., Guest, J. D., Fauvelle, C., Baumert, T. F., Bukh, J., Lloyd, A. R. & Foung, S. K. H., May 2019, In : PLoS pathogens. 15, 5, e1007772.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published
  14. Published
  15. Published

    Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies

    Tzarum, N., Giang, E., Kong, L., He, L., Prentoe, J., Augestad, E., Hua, Y., Castillo, S., Lauer, G. M., Bukh, J., Zhu, J., Wilson, I. A. & Law, M., 1 Jan 2019, In : Scientific American. 5, 1, p. eaav1882 eaav1882.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published
  17. Published

    Full-Length Open Reading Frame Amplification of Hepatitis C Virus

    Fahnøe, U. & Bukh, J., 2019, In : Methods in molecular biology (Clifton, N.J.). 1911, p. 85-91 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    In Vitro Neutralization Assay Using Cultured Hepatitis C Virus

    Prentoe, J. & Bukh, J., 2019, In : Methods in molecular biology (Clifton, N.J.). 1911, p. 433-439 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2018
  20. Published

    High density Huh7.5 cell hollow fiber bioreactor culture for high-yield production of hepatitis C virus and studies of antivirals

    Pihl, A. F., Offersgaard, A. F., Mathiesen, C. K., Prentoe, J., Fahnøe, U., Krarup, H., Bukh, J. & Gottwein, J. M., 30 Nov 2018, In : Scientific Reports. 8, 17505

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published
  22. Published

    Outcome and adverse events in patients with chronic hepatitis C treated with direct-acting antivirals: A clinical randomized study

    Sølund, C., Andersen, E. S., Mössner, B., Laursen, A. L., Røge, B. T., Kjær, M. S., Gerstoft, J., Christensen, P. B., Pedersen, M. S., Schønning, K., Fahnøe, U., Bukh, J. & Weis, N., 1 Oct 2018, In : European Journal of Gastroenterology and Hepatology. 30, 10, p. 1177-1186 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published
  24. Published

    Hypervariable Region 1 in Envelope Protein 2 of Hepatitis C Virus: A Linchpin in Neutralizing Antibody Evasion and Viral Entry

    Prentoe, J. & Bukh, J., 27 Sep 2018, In : Frontiers in Immunology. 9, 2146, p. 1-11

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published
  26. Published
  27. Published
  28. Published
  29. Published

    Direct acting antiviral treatment of chronic hepatitis C in Denmark: factors associated with and barriers to treatment initiation

    Sølund, C., Hallager, S., Pedersen, M. S., Fahnøe, U., Ernst, A., Krarup, H. B., Røge, B. T., Christensen, P. B., Laursen, A. L., Gerstoft, J., Bélard, E., Madsen, L. G., Schønning, K., Pedersen, A. G., Bukh, J., Weis, N. & Group, T. DANHEP., 1 May 2018, In : Scandinavian Journal of Gastroenterology. 53, 7, p. 849-856

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    IDENTIFICATION OF PIPERAZINYLBENZENESULFONAMIDES AS NEW INHIBITORS OF CLAUDIN-1 TRAFFICKING AND HEPATITIS C VIRUS ENTRY

    Riva, L., Song, O-R., Prentoe, J., Helle, F., L'homme, L., Gattolliat, C-H., Vandeputte, A., Fénéant, L., Belouzard, S., Baumert, T. F., Asselah, T., Bukh, J., Brodin, P., Cocquerel, L., Rouillé, Y. & Dubuisson, J., 1 May 2018, In : Journal of Virology. 92, 10

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Efficacy of NS5A Inhibitors Against Hepatitis C Virus Genotypes 1-7 and Escape Variants

    Gottwein, J. M., Pham, L. V., Mikkelsen, L. S., Ghanem, L., Ramirez, S., Scheel, T. K. H., Carlsen, T. H. R. & Bukh, J., Apr 2018, In : Gastroenterology. 154, 5, p. 1435-1448

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published
  33. Published

    Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies

    Bartenschlager, R., Baumert, T. F., Bukh, J., Houghton, M., Lemon, S. M., Lindenbach, B. D., Lohmann, V., Moradpour, D., Pietschmann, T., Rice, C. M., Thimme, R. & Wakita, T., Mar 2018, In : Virus Genes. 248, p. 53-62

    Research output: Contribution to journalReviewResearchpeer-review

  34. Published
  35. 2017
  36. Published
  37. Published

    Proposed revision to the taxonomy of the genus Pestivirus, family Flaviviridae

    Smith, D. B., Meyers, G., Bukh, J., Gould, E. A., Monath, T., Scott Muerhoff, A., Pletnev, A., Rico-Hesse, R., Stapleton, J. T., Simmonds, P. & Becher, P., 1 Aug 2017, In : The Journal of general virology. 98, 8, p. 2106-2112

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Broadening CD4(+) and CD8(+) T cell responses against hepatitis C virus by vaccination with NS3 overlapping peptide panels in cross-priming liposomes

    Filskov, J., Mikkelsen, M., Hansen, P. R., Christensen, J. P., Thomsen, A. R., Andersen, P., Bukh, J. & Agger, E. M., 1 Jul 2017, In : Journal of Virology. 91, 14

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Mouse models of acute and chronic hepacivirus infection

    Billerbeck, E., Wolfisberg, R., Fahnøe, U., Xiao, J. W., Quirk, C., Luna, J. M., Cullen, J. M., Hartlage, A. S., Chiriboga, L., Ghoshal, K., Lipkin, W. I., Bukh, J., Scheel, T. K. H., Kapoor, A. & Rice, C. M., 1 Jul 2017, In : Science. 357, 6347, p. 204-208

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published
  41. Published
  42. Published

    ICTV Virus Taxonomy Profile: Flaviviridae

    Simmonds, P., Becher, P., Bukh, J., Gould, E. A., Meyers, G., Monath, T., Muerhoff, S., Pletnev, A., Rico-Hesse, R., Smith, D. B., Stapleton, J. T. & Ictv Report Consortium, 1 Jan 2017, In : The Journal of general virology. 98, 1, p. 2-3

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. 2016
  44. Published

    HVR1-mediated antibody evasion of highly infectious in vivo adapted HCV in humanised mice

    Prentoe, J., Verhoye, L., Velázquez Moctezuma, R., Buysschaert, C., Farhoudi, A., Wang, R., Alter, H., Meuleman, P. & Bukh, J., Dec 2016, In : Gut. 65, p. 1988-1997

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Hypervariable region 1 shielding of hepatitis C virus is a main contributor to genotypic differences in neutralization sensitivity

    Prentoe, J., Velázquez-Moctezuma, R., Foung, S. K. H., Law, M. & Bukh, J., Dec 2016, In : Hepatology (Baltimore, Md.). 64, 6, p. 1881-1892

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Proposed update to the taxonomy of the genera Hepacivirus and Pegivirus within the Flaviviridae family

    Smith, D. B., Becher, P., Bukh, J., Gould, E. A., Meyers, G., Monath, T., Muerhoff, A. S., Pletnev, A., Rico-Hesse, R., Stapleton, J. T. & Simmonds, P., Nov 2016, In : The Journal of general virology. 97, 11, p. 2894-29070

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Robust HCV Genotype 3a Infectious Cell Culture System Permits Identification of Escape Variants With Resistance to Sofosbuvir

    Ramirez, S., Mikkelsen, L. S., Gottwein, J. M. & Bukh, J., Oct 2016, In : Gastroenterology. 151, p. 973-985

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published
  49. Published
  50. Published
  51. Published

    Functional analysis of microRNA-122 binding sequences of hepatitis C virus and identification of variants with high resistance against specific antagomir

    Li, Y-P., Pham, V. L., Uzcategui, N. & Bukh, J., Jul 2016, In : The Journal of general virology. 97, p. 1381-1394

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published
  53. Published

    Neutralizing antibodies in patients with chronic hepatitis C and correlation to liver cirrhosis and estimated duration of infection

    Pedersen, J., Lundbo, L. F., Krarup, H., Bukh, J. & Weis, N., Jun 2016, In : Journal of Medical Virology. 88, 10, p. 1791-1803

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published
  55. 2015
  56. Published
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