Jørgen Erik Nielsen

2018

Inflammatory markers of CHMP2B-mediated frontotemporal dementia

Roos, P., von Essen, M. R., Nielsen, T. T., Johannsen, P., Stokholm, J., Bie, A. S., Waldemar, G., Simonsen, A. H., Heslegrave, A., Zetterberg, H., Sellebjerg, F., Nielsen, J. E. & FReJA Consortium, 15 Nov 2018, In: Journal of Neuroimmunology. 324, p. 136-142 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study

Pottier, C., Zhou, X., Perkerson, R. B., Baker, M., Jenkins, G. D., Serie, D. J., Ghidoni, R., Benussi, L., Binetti, G., López de Munain, A., Zulaica, M., Moreno, F., Le Ber, I., Pasquier, F., Hannequin, D., Sánchez-Valle, R., Antonell, A., Lladó, A., Parsons, T. M. & Finch, N. A. & 113 others, Finger, E. C., Lippa, C. F., Huey, E. D., Neumann, M., Heutink, P., Synofzik, M., Wilke, C., Rissman, R. A., Slawek, J., Sitek, E., Johannsen, P., Nielsen, J. E., Ren, Y., van Blitterswijk, M., DeJesus-Hernandez, M., Christopher, E., Murray, M. E., Bieniek, K. F., Evers, B. M., Ferrari, C., Rollinson, S., Richardson, A., Scarpini, E., Fumagalli, G. G., Padovani, A., Hardy, J., Momeni, P., Ferrari, R., Frangipane, F., Maletta, R., Anfossi, M., Gallo, M., Petrucelli, L., Suh, E., Lopez, O. L., Wong, T. H., van Rooij, J. G. J., Seelaar, H., Mead, S., Caselli, R. J., Reiman, E. M., Noel Sabbagh, M., Kjolby, M., Nykjaer, A., Karydas, A. M., Boxer, A. L., Grinberg, L. T., Grafman, J., Spina, S., Oblak, A., Mesulam, M.-M., Weintraub, S., Geula, C., Hodges, J. R., Piguet, O., Brooks, W. S., Irwin, D. J., Trojanowski, J. Q., Lee, E. B., Josephs, K. A., Parisi, J. E., Ertekin-Taner, N., Knopman, D. S., Nacmias, B., Piaceri, I., Bagnoli, S., Sorbi, S., Gearing, M., Glass, J., Beach, T. G., Black, S. E., Masellis, M., Rogaeva, E., Vonsattel, J.-P., Honig, L. S., Kofler, J., Bruni, A. C., Snowden, J., Mann, D., Pickering-Brown, S., Diehl-Schmid, J., Winkelmann, J., Galimberti, D., Graff, C., Öijerstedt, L., Troakes, C., Al-Sarraj, S., Cruchaga, C., Cairns, N. J., Rohrer, J. D., Halliday, G. M., Kwok, J. B., van Swieten, J. C., White, C. L., Ghetti, B., Murell, J. R., Mackenzie, I. R. A., Hsiung, G.-Y. R., Borroni, B., Rossi, G., Tagliavini, F., Wszolek, Z. K., Petersen, R. C., Bigio, E. H., Grossman, M., Van Deerlin, V. M., Seeley, W. W., Miller, B. L., Graff-Radford, N. R., Boeve, B. F., Dickson, D. W., Biernacka, J. M. & Rademakers, R., Jun 2018, In: The Lancet Neurology. 17, 6, p. 548-558 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

90 Citations (Scopus)

Quantitative Measurements of Motor Function in Alzheimer's Disease, Frontotemporal Dementia, and Dementia with Lewy Bodies: A Proof-of-Concept Study

Jeppesen Kragh, F., Bruun, M., Budtz-Jørgensen, E., Hjermind, L. E., Schubert, R., Reilmann, R., Nielsen, J. E. & Hasselbalch, S. G., 26 Sept 2018, In: Dementia and Geriatric Cognitive Disorders. 46, 3-4, p. 168-179 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Reduced Cancer Incidence in Huntington's Disease: Analysis in the Registry Study

McNulty, P., Pilcher, R., Ramesh, R., Necuiniate, R., Hughes, A., Farewell, D., Holmans, P., Jones, L., Hjermind, L. E. (Member of study group), Nielsen, J. E. (Member of study group), Vangsted-Hansen, C. (Member of study group), Stokholm, J. (Member of study group), Lindquist, S. G. (Member of study group), Vinther-Jensen, T. (Member of study group) & REGISTRY investigators of the European Huntington's Disease Network, 2018, In: Journal of Huntington's disease. 7, 3, p. 209-222 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Sporadic Creutzfeldt-Jakob Disease in a Woman Married Into a Gerstmann-Sträussler-Scheinker Family: An Investigation of Prions Transmission via Microchimerism

Areškeviciute, A., Melchior, L. C., Broholm, H., Krarup, L.-H., Lindquist, S. G., Johansen, P., McKenzie, N., Green, A., Nielsen, J. E., Laursen, H. & Lund, E. L., 1 Aug 2018, In: Journal of Neuropathology and Experimental Neurology. 77, 8, p. 673-684 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

2017

A Novel TTBK2 De Novo Mutation in a Danish Family with Early-Onset Spinocerebellar Ataxia

Lindquist, S. G., Møller, L. B., Dali, C. I., Marner, L., Kamsteeg, E.-J., Nielsen, J. E. & Hjermind, L. E., 2017, In: Cerebellum. 16, 1, p. 268-71

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons

Aldana, B. I., Zhang, Y., Lihme, M. F., Bak, L. K., Nielsen, J. E., Holst, B., Hyttel, P., Freude, K. K. & Waagepetersen, H. S., Jun 2017, In: Neurochemistry International. 106, p. 48-61 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Defining active progressive multiple sclerosis

Sellebjerg, F., Börnsen, L., Ammitzbøll, C., Nielsen, J. E., Vinther-Jensen, T., Hjermind, L. E., von Essen, M., Ratzer, R. L., Soelberg Sørensen, P. & Romme Christensen, J., Nov 2017, In: Multiple sclerosis. 23, 13, p. 1727-1735 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutation

Clayton, E. L., Mancuso, R., Nielsen, T. T., Mizielinska, S., Holmes, H., Powell, N., Norona, F., Overgaard Larsen, J., Milioto, C., Wilson, K. M., Lythgoe, M. F., Ourselin, S., Nielsen, J. E., Johannsen, P., Holm, I., Collinge, J., Frej, A., Oliver, P. L., Gomez-Nicola, D. & Isaacs, A. M., 1 Mar 2017, In: Human Molecular Genetics. p. 873-887

Research output: Contribution to journal › Journal article › Research › peer-review

26 Citations (Scopus)

Evidence of oxidative stress and mitochondrial dysfunction in spinocerebellar ataxia type 2 (SCA2) patient fibroblasts: Effect of coenzyme Q10 supplementation on these parameters

Cornelius, N., Wardman, J. H., Hargreaves, I. P., Neergheen, V., Bie, A. S., Tümer, Z., Nielsen, J. E. & Nielsen, T. T., May 2017, In: Mitochondrion. 34, p. 103-114 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

48 Citations (Scopus)

Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases

Ferrari, R., Wang, Y., Vandrovcova, J., Guelfi, S., Witeolar, A., Karch, C. M., Schork, A. J., Fan, C. C., Brewer, J. B., Momeni, P., Schellenberg, G. D., Dillon, W. P., Sugrue, L. P., Hess, C. P., Yokoyama, J. S., Bonham, L. W., Rabinovici, G. D., Miller, B. L., Andreassen, O. A. & Dale, A. M. & 5 others, Hardy, J., Desikan, R. S., International FTD-Genomics Consortium (IFGC), Hjermind, L. E. (Member of study group) & Nielsen, J. E. (Member of study group), Feb 2017, In: Journal of neurology, neurosurgery, and psychiatry. 88, 2, p. 152-164 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

84 Citations (Scopus)

Hereditary cerebral small vessel disease and stroke

Søndergaard, C. B., Nielsen, J. E., Hansen, C. K. & Christensen, H. K., 22 Feb 2017, In: Clinical Neurology and Neurosurgery. 155, p. 45-57 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

61 Citations (Scopus)

Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study

Hensman Moss, D. J., Pardiñas, A. F., Langbehn, D., Lo, K., Leavitt, B. R., Roos, R., Durr, A., Mead, S., Holmans, P., Jones, L., Tabrizi, S. J., TRACK-HD investigators, Hjermind, L. E. (Member of study group) & Nielsen, J. E. (Member of study group), Sept 2017, In: The Lancet Neurology. 16, 9, p. 701-711 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

217 Citations (Scopus)

Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation

Ochalek, A., Mihalik, B., Avci, H. X., Chandrasekaran, A., Téglási, A., Bock, I., Giudice, M. L., Táncos, Z., Molnár, K., László, L., Nielsen, J. E., Holst, B., Freude, K., Hyttel, P., Kobolák, J. & Dinnyés, A., 1 Dec 2017, In: Alzheimer's research & therapy. 9, 1, p. 90

Research output: Contribution to journal › Journal article › Research › peer-review

151 Citations (Scopus)

Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B

Zhang, C.-Y., Schmid, B., Nikolaisen, N. K., Rasmussen, M. A., Aldana, B. I., Agger, M., Calloe, K., Stummann, T. C., Larsen, H. M., Nielsen, T. T., Huang, J., Xu, F., Liu, X., Bolund, L., Meyer, M., Bak, L. K., Waagepetersen, H. S., Luo, Y., Nielsen, J. E. & Holst, B. & 4 others, Clausen, C., Hyttel, P., Freude, K. K. & FReJA Consortium, 14 Mar 2017, In: Stem Cell Reviews and Reports. 8, 3, p. 648-658 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

68 Citations (Scopus)

SCA28: Novel Mutation in the AFG3L2 Proteolytic Domain Causes a Mild Cerebellar Syndrome with Selective Type-1 Muscle Fiber Atrophy

Svenstrup, K., Nielsen, T. T., Aidt, F., Rostgaard, N., Duno, M., Wibrand, F., Vinther-Jensen, T., Law, I., Vissing, J., Roos, P., Hjermind, L. E. & Nielsen, J. E., 2017, In: Cerebellum. 16, 1, p. 62-67

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

TMEM106B and ApoE polymorphisms in CHMP2B-mediated frontotemporal dementia (FTD-3)

Rostgaard, N., Roos, P., Budtz-Jørgensen, E., Johannsen, P., Waldemar, G., Nørremølle, A., Lindquist, S. G., Gydesen, S., Brown, J. M., Collinge, J., Isaacs, A. M., Nielsen, T. T., Nielsen, J. E. & FReJA collaboration, Nov 2017, In: Neurobiology of Aging. 59, p. 221.e1-221.e7

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

2016

Bevægeforstyrrelser, motorneuron sygdomme og hereditære sygdomme

Østergaard, K. & Nielsen, J. E., 2016, Medicin. Baslund, B., Feldt-Rasmussen, U., Kastrup, J. & Sørensen, P. S. (eds.). 2. ed. FADL's Forlag, p. 1013-1030

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

Clinical manifestations of intermediate allele carriers in Huntington disease

Cubo, E., Ramos-Arroyo, M. A., Martinez-Horta, S., Martínez-Descalls, A., Calvo, S., Gil-Polo, C., European HD Network (Lena Elisabeth Hjermind, Jørgen E Nielsen members), Hjermind, L. E. (Member of study group) & Nielsen, J. E. (Member of study group), 9 Aug 2016, In: Neurology. 87, 6, p. 571-8 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

44 Citations (Scopus)

Derivation of induced pluripotent stem cells from a familial Alzheimer's disease patient carrying the L282F mutation in presenilin 1

Poon, A., Li, T., Pires, C., Nielsen, T. T., Nielsen, J. E., Holst, B., Dinnyes, A., Hyttel, P. & Freude, K. K., 28 Sept 2016, In: Stem Cell Research. 17, 3, p. 470-473 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Disease stage, but not sex, predicts depression and psychological distress in Huntington's disease: A European population study

Dale, M., Maltby, J., Shimozaki, S., Cramp, R., Rickards, H., REGISTRY Investigators of the European Huntington's Disease Network, members: & Nielsen, J. E. (Member of study group), Jan 2016, In: Journal of Psychosomatic Research. 80, p. 17-22 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

32 Citations (Scopus)

Do I Misconstrue? Sarcasm Detection, Emotion Recognition, and Theory of Mind in Huntington Disease

Larsen, I. U., Vinther-Jensen, T., Gade, A., Nielsen, J. E. & Vogel, A., 2016, In: Neuropsychology. 30, 2, p. 181-189

Research output: Contribution to journal › Journal article › Research › peer-review

28 Citations (Scopus)

Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1

Pires, C., Schmid, B., Petræus, C., Poon, A., Nimsanor, N., Nielsen, T. T., Waldemar, G., Hjermind, L. E., Nielsen, J. E., Hyttel, P. & Freude, K. K., Sept 2016, In: Stem Cell Research. 17, 2, p. 285-288 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

37 Citations (Scopus)

Generation of a gene-corrected isogenic control hiPSC line derived from a familial Alzheimer's disease patient carrying a L150P mutation in presenilin 1

Poon, A., Schmid, B., Pires, C., Nielsen, T. T., Hjermind, L. E., Nielsen, J. E., Holst, B., Hyttel, P. & Freude, K. K., 24 Sept 2016, In: Stem Cell Research. 17, 3, p. 466-469 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

30 Citations (Scopus)

Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific heterozygous mutation in CHMP2B

Zhang, Y., Schmid, B., Nielsen, T. T., Nielsen, J. E., Clausen, C., Hyttel, P., Holst, B. & Freude, K. K., 16 Jun 2016, In: Stem Cell Research. 17, 1, p. 148-150 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific homozygous mutation in CHMP2B

Zhang, Y., Schmid, B., Nielsen, T. T., Nielsen, J. E., Clausen, C., Hyttel, P., Holst, B. & Freude, K. K., 2016, In: Stem Cell Research. 17, 1, p. 151-153 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H196

Marthaler, A. G., Schmid, B., Tubsuwan, A., Poulsen, U. B., Engelbrecht, A. F., Mau-Holzmann, U. A., Hyttel, P., Nielsen, J. E., Nielsen, T. T. & Holst, B., Jan 2016, In: Stem Cell Research. 16, 1, p. 162-5 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H266

Marthaler, A. G., Tubsuwan, A., Schmid, B., Poulsen, U. B., Engelbrecht, A. F., Mau-Holzmann, U. A., Hyttel, P., Nielsen, T. T., Nielsen, J. E. & Holst, B., Jan 2016, In: Stem Cell Research. 16, 1, p. 202-5 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H271

Marthaler, A. G., Schmid, B., Tubsuwan, A., Poulsen, U. B., Engelbrecht, A. F., Mau-Holzmann, U. A., Hyttel, P., Nielsen, J. E., Nielsen, T. T. & Holst, B., Jan 2016, In: Stem Cell Research. 16, 1, p. 180-3 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Generation of an isogenic, gene-corrected iPSC line from a pre-symptomatic 28-year-old woman with an R406W mutation in the microtubule associated protein tau (MAPT) gene

Nimsanor, N., Poulsen, U., Rasmussen, M. A., Clausen, C., Mau-Holzmann, U. A., Nielsen, J. E., Nielsen, T. T., Hyttel, P., Holst, B. & Schmid, B., 28 Sept 2016, In: Stem Cell Research. 17, 3, p. 600-602 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Generation of an isogenic, gene-corrected iPSC line from a symptomatic 57-year-old female patient with frontotemporal dementia caused by a P301L mutation in the microtubule associated protein tau (MAPT) gene

Nimsanor, N., Kitiyanant, N., Poulsen, U., Rasmussen, M. A., Clausen, C., Mau-Holzmann, U. A., Nielsen, J. E., Nielsen, T. T., Hyttel, P., Holst, B. & Schmid, B., 28 Sept 2016, In: Stem Cell Research. 17, 3, p. 556-559 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Generation of an isogenic, gene-corrected iPSC line from a symptomatic 59-year-old female patient with frontotemporal dementia caused by an R406W mutation in the microtubule associated protein tau (MAPT) gene

Nimsanor, N., Poulsen, U., Rasmussen, M. A., Clausen, C., Mau-Holzmann, U. A., Nielsen, J. E., Nielsen, T. T., Hyttel, P., Holst, B. & Schmid, B., 28 Sept 2016, In: Stem Cell Research. 17, 3, p. 576-579 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1

Tubsuwan, A., Pires, C., Rasmussen, M. A., Schmid, B., Nielsen, J. E., Hjermind, L. E., Hall, V., Nielsen, T. T., Waldemar, G., Hyttel, P., Clausen, C., Kitiyanant, N., Freude, K. K. & Holst, B., Jan 2016, In: Stem Cell Research. 16, 1, p. 110-2 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a M146I mutation in PSEN1

Li, T., Pires, C., Nielsen, T. T., Waldemar, G., Hjermind, L. E., Nielsen, J. E., Dinnyes, A., Holst, B., Hyttel, P. & Freude, K. K., Mar 2016, In: Stem Cell Research. 16, 2, p. 334-7 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying an A79V mutation in PSEN1

Li, T., Pires, C., Nielsen, T. T., Waldemar, G., Hjermind, L. E., Nielsen, J. E., Dinnyes, A., Hyttel, P. & Freude, K. K., Mar 2016, In: Stem Cell Research. 16, 2, p. 229-32 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H196

Marthaler, A. G., Schmid, B., Tubsuwan, A., Poulsen, U. B., Hyttel, P., Nielsen, T. T., Nielsen, J. E. & Holst, B., Jan 2016, In: Stem Cell Research. 16, 1, p. 199-201 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H266

Marthaler, A. G., Schmid, B., Tubsuwan, A., Poulsen, U. B., Hyttel, P., Nielsen, T. T., Nielsen, J. E. & Holst, B., Jan 2016, In: Stem Cell Research. 16, 1, p. 166-9 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H271

Marthaler, A. G., Tubsuwan, A., Schmid, B., Poulsen, U. B., Hyttel, P., Nielsen, J. E., Nielsen, T. T. & Holst, B., Jan 2016, In: Stem Cell Research. 16, 1, p. 159-61 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Generation of spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cell line SCA3.A11

Hansen, S. K., Borland, H., Hasholt, L. F., Tümer, Z., Nielsen, J. E., Rasmussen, M. A., Nielsen, T. T., Stummann, T. C., Fog, K. & Hyttel, P., May 2016, In: Stem Cell Research. 16, 3, p. 553-6 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Generation of spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cell line SCA3.B11

Hansen, S. K., Borland, H., Hasholt, L. F., Tümer, Z., Nielsen, J. E., Rasmussen, M. A., Nielsen, T. T., Stummann, T. C., Fog, K. & Hyttel, P., May 2016, In: Stem Cell Research. 16, 3, p. 589-92 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Induced pluripotent stem cell - derived neurons for the study of spinocerebellar ataxia type 3

Hansen, S. K., Stummann, T. C., Borland, H., Hasholt, L. F., Tümer, Z., Nielsen, J. E., Rasmussen, M. A., Nielsen, T. T., Daechsel, J. C. A., Fog, K. & Hyttel, P., 16 Aug 2016, In: Stem Cell Research. 17, 2, p. 306-317 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a P301L mutation in microtubule-associated protein tau (MAPT)

Rasmussen, M. A., Hjermind, L. E., Hasholt, L. F., Waldemar, G., Nielsen, J. E., Clausen, C., Hyttel, P. & Holst, B., Jan 2016, In: Stem Cell Research. 16, 1, p. 70-4 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a R406W mutation in microtubule-associated protein tau (MAPT)

Rasmussen, M. A., Hjermind, L. E., Hasholt, L. F., Waldemar, G., Nielsen, J. E., Clausen, C., Hyttel, P. & Holst, B., Jan 2016, In: Stem Cell Research. 16, 1, p. 75-8 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Induced pluripotent stem cells (iPSCs) derived from a pre-symptomatic carrier of a R406W mutation in microtubule-associated protein tau (MAPT) causing frontotemporal dementia

Rasmussen, M. A., Hjermind, L. E., Hasholt, L. F., Waldemar, G., Nielsen, J. E., Clausen, C., Hyttel, P. & Holst, B., Jan 2016, In: Stem Cell Research. 16, 1, p. 105-9 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Induced pluripotent stem cells (iPSCs) derived from a symptomatic carrier of a S305I mutation in the microtubule-associated protein tau (MAPT)-gene causing frontotemporal dementia

Nimsanor, N., Jørring, I., Rasmussen, M. A., Clausen, C., Mau-Holzmann, U. A., Kitiyanant, N., Nielsen, J. E., Nielsen, T. T., Hyttel, P., Holst, B. & Schmid, B., 20 Oct 2016, In: Stem Cell Research. 17, 3, p. 564-567 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Liver function in Huntington's disease assessed by blood biochemical analyses in a clinical setting

Nielsen, S. M. B., Vinther-Jensen, T., Nielsen, J. E., Nørremølle, A., Hasholt, L., Hjermind, L. E. & Josefsen, K., 15 Mar 2016, In: Journal of the Neurological Sciences. 362, p. 326-32 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Personality traits in Huntington's disease: An exploratory study of gene expansion carriers and non-carriers

Larsen, I. U., Mortensen, E. L., Vinther-Jensen, T., Nielsen, J. E., Knudsen, G. M. & Vogel, A., Dec 2016, In: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 171, 8, p. 1153-1160 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Psychiatric and cognitive symptoms in Huntington's disease are modified by polymorphisms in catecholamine regulating enzyme genes

Vinther-Jensen, T., Nielsen, T. T., Budtz-Jørgensen, E., Larsen, I. U., Hansen, M. M., Hasholt, L., Hjermind, L. E., Nielsen, J. E. & Nørremølle, A., 2016, In: Clinical Genetics. 89, 3, p. 320-7

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Selected CSF biomarkers indicate no evidence of early neuroinflammation in Huntington disease

Vinther-Jensen, T., Börnsen, L., Budtz-Jørgensen, E., Ammitzbøll, C., Larsen, I. U., Hjermind, L. E., Sellebjerg, F. & Nielsen, J. E., Dec 2016, In: Neurology® neuroimmunology & neuroinflammation. 3, 6, p. e287

Research output: Contribution to journal › Journal article › Research › peer-review

42 Citations (Scopus)

Social Cognition, Executive Functions and Self-Report of Psychological Distress in Huntington's Disease

Larsen, I. U., Vinther-Jensen, T., Nielsen, J. E., Gade, A. & Vogel, A., 28 Dec 2016, In: PLoS Currents. 8, p. E

Research output: Contribution to journal › Journal article › Research › peer-review

Jørgen Erik Nielsen

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