Research output per year
Research output per year
Personal profile
Expertises
Translational biomedical research
"Main research areas
Cystic fibrosis; persistent bacterial infections; antibiotic resistance; whole genome sequencing; persisters; transcriptomics; metabolism.
Current research
The research area is (shared research between RH and DTU) bacterial airway infections in patients with cystic fibrosis (CF). Most CF patients have bacteria in their lungs from early childhood until they die prematurely. The bacterial lung infections in CF patients, is an excellent model to study infectious disease for which antibiotic treatment is challenged by frequent lack of success. Equally important is that modern human life-style, as well as increases in the average population life span, will create problems with long-term bacterial infections that are difficult or impossible to treat. Moreover, the rising global problem of antibiotic resistance threatens to become the biggest health risk within the next 20-30 years. Our research is directly addressing the problem of antibiotic resistance.
Potential conflicts of interest
None.
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Research output
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Achromobacter spp. in a Cohort of Non-Selected Pre-and Post-Lung Transplant Recipients
Crone, C. G., Rezahosseini, O., Schultz, H. H. L., Qvist, T., Johansen, H. K., Nielsen, S. D. & Perch, M., 28 Jan 2022, In: Pathogens. 11, 2, 11 p., 181.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Diagnostic criteria of CNS infection in patients with external ventricular drainage after traumatic brain injury: a pilot study
Willer-Hansen, R. S., Olsen, M. H., Hauerberg, J., Johansen, H. K., Andersen, Å. B. & Møller, K., Apr 2022, In: Acta Anaesthesiologica Scandinavica. 66, 4, p. 507-515 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inter-species interactions alter antibiotic efficacy in bacterial communities
Bottery, M. J., Matthews, J. L., Wood, A. J., Johansen, H. K., Pitchford, J. W. & Friman, V-P., Mar 2022, In: ISME Journal. 16, 3, p. 812-821 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Longitudinal Evolution of the Pseudomonas-Derived Cephalosporinase (PDC) Structure and Activity in a Cystic Fibrosis Patient Treated with β-Lactams
Colque, C. A., Albarracín Orio, A. G., Tomatis, P. E., Dotta, G., Moreno, D. M., Hedemann, L. G., Hickman, R. A., Sommer, L. M., Feliziani, S., Moyano, A. J., Bonomo, R. A., K Johansen, H., Molin, S., Vila, A. J. & Smania, A. M., 26 Oct 2022, In: mBio. 13, 5, p. e0166322 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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'Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistance': author's response
Goltermann, L., Johansen, H. K., Molin, S. & La Rosa, R., Dec 2022, In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 28, 12, p. 1667-1668 2 p.Research output: Contribution to journal › Letter › peer-review
Activities
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Cochrane Nordic 25th Anniversary Research Symposium
Peter C. Gøtzsche (Organizer), Peter C. Gøtzsche (Speaker), Asbjørn Hróbjartsson (Speaker), Britta Tendal (Speaker), Helle Krogh Johansen (Speaker), Karsten Juhl Jørgensen (Speaker), Lasse T. Krogsbøll (Speaker), Tom Jefferson (Speaker), Andreas Lundh (Speaker), Jeppe B. Schroll (Speaker), Lars Jørgensen (Speaker), Emma Theresa Maund (Speaker), Tarang V. Sharma (Organizer), Jakobsen Janus Christian (Speaker), Anders Klokmose Sørensen (Speaker) & Margrethe Nielsen (Organizer)
12 Oct 2018Activity: Participating in or organising an event › Organisation of and participation in conference
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Co-supervisor til PhD Thesis for Fatima AlZahra'a Alatraktchi
Helle Krogh Johansen (Participant)
2018Activity: Other
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P. aeruginosa og CF
Helle Krogh Johansen (Lecturer)
9 Sep 2010 → 11 Sep 2010Activity: Talk or presentation › Lecture and oral contribution
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The paranasal sinuses are focus for colonisation and chronic biofilm infection in CF patients
Helle Krogh Johansen (Lecturer)
17 Aug 2010Activity: Talk or presentation › Lecture and oral contribution
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Sinus Infections
Helle Krogh Johansen (Lecturer)
16 Jun 2010 → 19 Jun 2010Activity: Talk or presentation › Lecture and oral contribution