Research output per year
Research output per year
Personal profile
Expertises
Translational biomedical research
Main research areas
Cystic fibrosis; persistent bacterial infections; antibiotic resistance; whole genome sequencing; persisters; transcriptomics; metabolism.
Current research
The research area is (shared research between RH and DTU) bacterial airway infections in patients with cystic fibrosis (CF). Most CF patients have bacteria in their lungs from early childhood until they die prematurely. The bacterial lung infections in CF patients, is an excellent model to study infectious disease for which antibiotic treatment is challenged by frequent lack of success. Equally important is that modern human life-style, as well as increases in the average population life span, will create problems with long-term bacterial infections that are difficult or impossible to treat. Moreover, the rising global problem of antibiotic resistance threatens to become the biggest health risk within the next 20-30 years. Our research is directly addressing the problem of antibiotic resistance.
Potential conflicts of interest
None.
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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A Dedicated Mycosis Flask Increases the Likelihood of Identifying Candidemia Sepsis
Ahlström, M. G., Antsupova, V. S., Pedersen, M., Johansen, H. K., Hansen, D. S. & Knudsen, I. J. D., 4 Apr 2023, In: Journal of fungi (Basel, Switzerland). 9, 4, 441.Research output: Contribution to journal › Journal article › Research › peer-review
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Antimicrobial resistance of Pseudomonas aeruginosa in a cystic fibrosis population after introduction of a novel cephalosporin/β-lactamase inhibitor combination
Katzenstein, T. L., Faurholt-Jepsen, D., Qvist, T., Jensen, P. Ø., Pressler, T., Johansen, H. K. & Kolpen, M., Aug 2023, In: APMIS - Journal of Pathology, Microbiology and Immunology. 131, 8, p. 419-425 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhalation devices and inhaled corticosteroids particle size influence on severe pneumonia in patients with chronic obstructive pulmonary disease: a nationwide cohort study
Heerfordt, C. K., Rønn, C., Harboe, Z. B., Ingebrigtsen, T. S., Svorre Jordan, A., Wilcke, J. T., Bonnesen, B., Biering-Sørensen, T., Sørensen, R., Holler, J. G., Itenov, T. S., Johansen, H. K., Sivapalan, P., Eklöf, J. & Jensen, J-U. S., Sep 2023, In: BMJ Open Respiratory Research. 10, 1, e001814.Research output: Contribution to journal › Journal article › Research › peer-review
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Long-term evolution of antibiotic tolerance in Pseudomonas aeruginosa lung infections
Ghoul, M., Andersen, S. B., Marvig, R. L., Johansen, H. K., Jelsbak, L., Molin, S., Perron, G. & Griffin, A. S., Dec 2023, In: Evolution letters. 7, 6, p. 389-400 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The small non-coding RNA B11 regulates multiple facets of Mycobacterium abscessus virulence
Bar-Oz, M., Martini, M. C., Alonso, M. N., Meir, M., Lore, N. I., Miotto, P., Riva, C., Angala, S. K., Xiao, J., Masiello, C. S., Misiakou, M-A., Sun, H., Moy, J. K., Jackson, M., Johansen, H. K., Cirillo, D. M., Shell, S. S. & Barkan, D., 21 Aug 2023, (E-pub ahead of print) In: P L o S Pathogens (Online). 19, 8, p. e1011575 e1011575.Research output: Contribution to journal › Journal article › Research › peer-review
Activities
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Cochrane Nordic 25th Anniversary Research Symposium
Peter C. Gøtzsche (Organizer), Peter C. Gøtzsche (Speaker), Asbjørn Hróbjartsson (Speaker), Britta Tendal (Speaker), Helle Krogh Johansen (Speaker), Karsten Juhl Jørgensen (Speaker), Lasse T. Krogsbøll (Speaker), Tom Jefferson (Speaker), Andreas Lundh (Speaker), Jeppe B. Schroll (Speaker), Lars Jørgensen (Speaker), Emma Theresa Maund (Speaker), Tarang V. Sharma (Organizer), Jakobsen Janus Christian (Speaker), Anders Klokmose Sørensen (Speaker) & Margrethe Nielsen (Organizer)
12 Oct 2018Activity: Participating in or organising an event › Organisation of and participation in conference
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Co-supervisor til PhD Thesis for Fatima AlZahra'a Alatraktchi
Helle Krogh Johansen (Participant)
2018Activity: Other
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P. aeruginosa og CF
Helle Krogh Johansen (Lecturer)
9 Sep 2010 → 11 Sep 2010Activity: Talk or presentation › Lecture and oral contribution
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The paranasal sinuses are focus for colonisation and chronic biofilm infection in CF patients
Helle Krogh Johansen (Lecturer)
17 Aug 2010Activity: Talk or presentation › Lecture and oral contribution
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Sinus Infections
Helle Krogh Johansen (Lecturer)
16 Jun 2010 → 19 Jun 2010Activity: Talk or presentation › Lecture and oral contribution