Research
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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Expertises

Clinical translational research on the origins of asthma, atopic dermatitis and allergy. Main contributions:

I.               Inflammation in asthma

II.             Lung function assessment in young children

III.           Asthma therapy and prevention in children

IV.            Genetics in atopic diseases

V.              Microbiome in the early life of asthmatics

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Main research areas

The Copenhagen Prospective Studies on Asthma in Childhood (COPSAC) mother-child cohorts of a total of 1100 children in two main cohorts: COPSAC2000 and COPSAC2010 are being followed closely at the research clinic combining unique extensive clinical data and a comprehensive biobank with cutting-edge interdisciplinary basic research, including genome wide scanning, epigenetics, sequencing of the microbiome in multiple human compartments, and longitudinal metabolomics to develop a differentiated characterization of the disease processes based on a systems biology approach. 

Current research

-       The role of the human microbiome in shaping health or disease in the early life

-       Genetics in asthma, allergy and atopic dermatitis

-       The effect of vitamin D supplementation in pregnancy based on a randomized controlled trial (RCT)

-       The effect of fish oil (PUFA) supplementation in pregnancy on the offspring, based on a RCT

-       Low-grade inflammation before the onset of childhood asthma

-       Lung function trajectories from birth to adulthood

-       National registries based studies supporting our findings in the clinic

Potential conflicts of interest

Consultant at Chiesi Pharmaceuticals and Boeringher-Ingelheim, unrelated to the above

ID: 9997