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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2021
  2. Published
  3. Published
  4. Published

    Effects of a single dose of psilocybin on behaviour, brain 5-HT2A receptor occupancy and gene expression in the pig

    Donovan, L. L., Johansen, J. V., Ros, N. F., Jaberi, E., Linnet, K., Johansen, S. S., Ozenne, B., Issazadeh-Navikas, S., Hansen, H. D. & Knudsen, G. M., Jan 2021, In: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 42, p. 1-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2020
  6. Published
  7. Published
  8. Published

    Advances in simultaneous PET/MR for imaging neuroreceptor function

    Sander, C. Y., Hansen, H. D. & Wey, H-Y., Jun 2020, In: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 40, 6, p. 1148-1166 19 p.

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    Imaging HDACs In Vivo: Cross-Validation of the [11C]Martinostat Radioligand in the Pig Brain

    Donovan, L. L., Magnussen, J. H., Dyssegaard, A., Lehel, S., Hooker, J. M., Knudsen, G. M. & Hansen, H. D., Jun 2020, In: Molecular Imaging and Biology. 22, 3, p. 569-577 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published
  11. Published

    Radiosynthesis and preclinical evaluation of [C-11]Cimbi-701-Towards the imaging of cerebral 5-HT7 receptors

    L 'Estrade, E. T., Shalgunov, V., Edgar, F. G., Strebl-Bantillo, M. G., Xiong, M., Crestey, F., Neelamegam, R., Dyssegaard, A., Lehel, S., Erlandsson, M., Ohlsson, T., Hooker, J. M., Knudsen, G. M., Herth, M. M. & Hansen, H. D., Feb 2020, In: Journal of Labelled Compounds and Radiopharmaceuticals. 63, 2, p. 46-55 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2019
  13. Published

    Human biodistribution and radiation dosimetry of the 5-HT2A receptor agonist Cimbi-36 labeled with carbon-11 in two positions

    Johansen, A., Holm, S., Dall, B., Keller, S., Kristensen, J. L., Knudsen, G. M. & Hansen, H. D., 31 Jul 2019, In: EJNMMI Research. 9, 1, p. 71

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Association Between Sumatriptan Treatment During a Migraine Attack and Central 5-HT1B Receptor Binding

    Deen, M., Hougaard, A., Hansen, H. D., Schain, M., Dyssegaard, A., Knudsen, G. M. & Ashina, M., 1 Jul 2019, In: JAMA Neurology. 76, 7, p. 834-840 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Synthesis and Pharmacological Evaluation of [11C]4-Methoxy-N-[2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the δ-Subunit-Containing γ-Aminobutyric Acid Type A Receptors

    L'Estrade, E. T., Hansen, H. D., Falk-Petersen, C., Haugaard, A., Griem-Krey, N., Jung, S., Lüddens, H., Schirmeister, T., Erlandsson, M., Ohlsson, T., Knudsen, G. M., Herth, M. M., Wellendorph, P. & Frølund, B., 31 May 2019, In: ACS omega. 4, 5, p. 8846-8851 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Improved radiosynthesis and preliminary in vivo evaluation of the 11C-labeled tetrazine [11C]AE-1 for pretargeted PET imaging

    Stéen, E. J. L., Jørgensen, J. T., Petersen, I. N., Nørregaard, K., Lehel, S., Shalgunov, V., Birke, A., Edem, P. E., L'Estrade, E. T., Hansen, H. D., Villadsen, J., Erlandsson, M., Ohlsson, T., Yazdani, A., Valliant, J. F., Kristensen, J. L., Barz, M., Knudsen, G. M., Kjær, A. & Herth, M. M., 15 Apr 2019, In: Bioorganic & Medicinal Chemistry Letters. 29, 8, p. 986-990 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Migraine is associated with high brain 5-HT levels as indexed by 5-HT4 receptor binding

    Deen, M., Hougaard, A., Hansen, H. D., Svarer, C., Eiberg, H., Lehel, S., Knudsen, G. M. & Ashina, M., 1 Apr 2019, In: Cephalalgia. 39, 4, p. 526-532 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Evaluation of [18 F]2FP3 in pigs and non-human primates

    Hansen, H. D., Constantinescu, C. C., Barret, O., Herth, M. M., Magnussen, J. H., Lehel, S., Dyssegaard, A., Colomb, J., Billard, T., Zimmer, L., Tamagnan, G. & Knudsen, G. M., 1 Jan 2019, In: Journal of Labelled Compounds and Radiopharmaceuticals. 62, 1, p. 34-42 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2018
  20. Published

    Classics in Neuroimaging: The Serotonergic 2A Receptor System-from Discovery to Modern Molecular Imaging

    T L'Estrade, E., Hansen, H. D., Erlandsson, M., Ohlsson, T. G., Knudsen, G. M. & Herth, M. M., 20 Jun 2018, In: ACS Chemical Neuroscience. 9, 6, p. 1226-1229 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published
  22. Published

    High brain serotonin levels in migraine between attacks: A 5-HTreceptor binding PET study

    Deen, M., Hansen, H. D., Hougaard, A., Nørgaard, M., Eiberg, H., Lehel, S., Ashina, M. & Knudsen, G. M., 28 Jan 2018, In: NeuroImage. Clinical. 18, p. 97-102 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Automatic delineation of brain regions on MRI and PET images from the pig

    Villadsen, J., Hansen, H. D., Jørgensen, L. M., Keller, S. H., Andersen, F. L., Petersen, I. N., Knudsen, G. M. & Svarer, C., 15 Jan 2018, In: Journal of Neuroscience Methods. 294, p. 51-58 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published
  25. 2017
  26. Published

    Functional Characterization of 5-HT1B Receptor Drugs in Nonhuman Primates Using Simultaneous PET-MR

    Hansen, H. D., Mandeville, J. B., Sander, C. Y., Hooker, J. M., Catana, C., Rosen, B. R. & Knudsen, G. M., 1 Nov 2017, In: The Journal of Neuroscience : the official journal of the Society for Neuroscience. 37, 44, p. 10671-10678 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Synthesis, radiofluorination, and preliminary evaluation of the potential 5-HT2A receptor agonists [(18) F]Cimbi-92 and [(18) F]Cimbi-150

    Edgar, F. G., Hansen, H. D., Leth-Petersen, S., Ettrup, A., Kristensen, J. L., Knudsen, G. M. & Herth, M. M., Oct 2017, In: Journal of Labelled Compounds and Radiopharmaceuticals. 60, 12, p. 586-591 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published
  29. Published

    (18)F-Labelling of electron rich iodonium ylides: application to the radiosynthesis of potential 5-HT2A receptor PET ligands

    Petersen, I. N., Villadsen, J., Hansen, H. D., Madsen, J., Jensen, A. A., Gillings, N., Lehel, S., Herth, M. M., Knudsen, G. M. & Kristensen, J. L., 23 May 2017, In: Organic & biomolecular chemistry. 15, 20, p. 4351-4358 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Radiosynthesis and Evaluation of [(11)C]3-Hydroxycyclopent-1-enecarboxylic Acid as Potential PET Ligand for the High-Affinity γ-Hydroxybutyric Acid Binding Sites

    Jensen, C. H., Hansen, H. D., Bay, T., Vogensen, S. B., Lehel, S., Thiesen, L., Bundgaard, C., Clausen, R. P., Knudsen, G. M., Herth, M. M., Wellendorph, P. & Frølund, B., 18 Jan 2017, In: ACS Chemical Neuroscience. 8, 1, p. 22-27 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published
  32. Published
  33. 2016
  34. Published

    Convergent (18)F-labeling and evaluation of N-benzyl-phenethylamines as 5-HT2A receptor PET ligands

    Petersen, I. N., Villadsen, J., Hansen, H. D., Jensen, A. A., Lehel, S., Gillings, N., Herth, M. M., Knudsen, G. M. & Kristensen, J. L., 1 Nov 2016, In: Bioorganic and Medicinal Chemistry. 24, 21, p. 5353-5356 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Autoradiographic imaging and quantification of the high-affinity GHB binding sites in rodent brain using (3)H-HOCPCA

    Klein, A. B., Bay, T., Villumsen, I. S., Falk-Petersen, C. B., Marek, A., Frølund, B., Clausen, R. P., Hansen, H. D., Knudsen, G. M. & Wellendorph, P., Nov 2016, In: Neurochemistry International. 100, p. 138-145 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    A regularized full reference tissue model for PET neuroreceptor mapping

    Mandeville, J. B., Sander, C. Y. M., Wey, H-Y., Hooker, J. M., Hansen, H. D., Svarer, C., Knudsen, G. M. & Rosen, B. R., 27 Jun 2016, In: NeuroImage. 139, p. 405-414 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Synthesis and evaluation of (18)F-labeled 5-HT2A receptor agonists as PET ligands

    Herth, M. M., Petersen, I. N., Hansen, H. D., Hansen, M., Ettrup, A., Jensen, A. A., Lehel, S., Dyssegaard, A., Gillings, N., Knudsen, G. M. & Kristensen, J. L., 19 Apr 2016, In: Nuclear Medicine and Biology. 43, 8, p. 455-462 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Metabolic Fate of Hallucinogenic NBOMes

    Leth-Petersen, S., Gabel-Jensen, C., Gillings, N., Lehel, S., Hansen, H. D., Knudsen, G. M. & Kristensen, J. L., 19 Jan 2016, In: Chemical Research in Toxicology. 29, 1, p. 96-100 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The Center for Integrated Molecular Brain Imaging (Cimbi) database

    Knudsen, G. M., Jensen, P. S., Erritzoe, D., Baaré, W. F. C., Ettrup, A., Fisher, P. M., Gillings, N., Hansen, H. D., Hansen, L. K., Hasselbalch, S. G., Henningsson, S., Herth, M. M., Holst, K. K., Iversen, P., Kessing, L. V., Macoveanu, J., Madsen, K. S., Mortensen, E. L., Nielsen, F. Å., Paulson, O. B., Siebner, H. R., Stenbæk, D. S., Svarer, C., Jernigan, T. L., Strother, S. C. & Frokjaer, V. G., 1 Jan 2016, In: NeuroImage. 124, p. 1213-1219 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published
  41. 2015
  42. Published

    Labeling and preliminary in vivo evaluation of the 5-HT(7) receptor selective agonist [(11)C]E-55888

    Hansen, H. D., Lykke Andersen, V., Lehel, S., Magnussen, J. H., Dyssegaard, A., Stroth, N., Kristensen, J. L., Knudsen, G. M. & Herth, M. M., 1 May 2015, In: Bioorganic & Medicinal Chemistry Letters. 25, 9, p. 1901-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published
  44. Published

    (11)C-labeling and preliminary evaluation of pimavanserin as a 5-HT2A receptor PET-radioligand

    Lykke Andersen, V., Hansen, H. D., Herth, M. M., Dyssegaard, A., Knudsen, G. M. & Kristensen, J. L., 1 Mar 2015, In: Bioorganic & Medicinal Chemistry Letters. 25, 5, p. 1053-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2014
  46. Published

    (11)C-labeling and preliminary evaluation of vortioxetine as a PET radioligand

    Lykke Andersen, V., Hansen, H. D., Herth, M. M., Knudsen, G. M. & Langgaard Kristensen, J., 1 Jun 2014, In: Bioorganic & Medicinal Chemistry Letters. 24, 11, p. 2408-11 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Synthesis, radiolabeling and in vivo evaluation of [(11)C](R)-1-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]-3-(2-pyrazinyloxy)-2-propanol, a potential PET radioligand for the 5-HT(7) receptor

    Hansen, H. D., Lacivita, E., Di Pilato, P., Herth, M. M., Lehel, S., Ettrup, A., Lykke Andersen, V., Dyssegaard, A., De Giorgio, P., Perrone, R., Berardi, F., Colabufo, N. A., Niso, M., Knudsen, G. M. & Leopoldo, M., 22 May 2014, In: European Journal of Medicinal Chemistry. 79, p. 152-63 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published
  49. Published

    Design, synthesis, radiolabeling and in vivo evaluation of potential positron emission tomography (PET) radioligands for brain imaging of the 5-HT7 receptor

    Lacivita, E., Niso, M., Hansen, H. D., Di Pilato, P., Herth, M. M., Lehel, S., Ettrup, A., Montenegro, L., Perrone, R., Berardi, F., Colabufo, N. A., Leopoldo, M. & Knudsen, G. M., 23 Jan 2014, In: Bioorganic & Medicinal Chemistry. 22, 5, p. 1736-1750

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. 2013
  51. Published

    Evaluation of PET radioligands for the cerebral 5-HT7 and 5-HT2A receptors (Ph.d.)

    Hansen, H. D., 11 Oct 2013, København: København: Eget forlag. 64 p.

    Research output: Book/ReportPh.D. thesis

  52. Published

ID: 41459031