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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2019
  2. Published

    The concentration of the cleaved suPAR forms in pre- and postoperative plasma samples improves the prediction of survival in colorectal cancer: A nationwide multicenter validation and discovery study

    Danish Collaborative Research Group on Colorectal Cancer, Dec 2019, In : Journal of Surgical Oncology. 120, 8, p. 1404-1411 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Crystal structure of the unoccupied murine urokinase-type plasminogen activator receptor (uPAR) reveals a tightly packed DII-DIII unit

    Liu, M., Lin, L., Hansen, G. H., Ploug, M., Hanlin, L., Jiang, L., Yuan, C., Li, J. & Huang, M., 2 May 2019, In : FEBS Letters.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2018
  5. Published

    Antibody-Mediated Neutralization of uPA Proteolytic Function Reduces Disease Progression in Mouse Arthritis Models

    Almholt, K., Hebsgaard, J. B., Nansen, A., Andersson, C., Pass, J., Rønø, B., Thygesen, P., Pelzer, H., Loftager, M., Lund, I. K., Høyer-Hansen, G., Frisch, T., Jensen, C. H., Otte, K. S., Søe, N. H., Bartels, E. M., Andersen, M., Bliddal, H. & Usher, P. A., 1 Feb 2018, In : Journal of immunology (Baltimore, Md. : 1950). 200, 3, p. 957-965

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published
  7. 2017
  8. Published
  9. 2016
  10. Published
  11. Published
  12. Published
  13. Published
  14. Published

    Copenhagen uPAR prostate cancer (CuPCa) database: protocol and early results

    Lippert, S., Berg, K. D., Høyer-Hansen, G., Lund, I. K., Iversen, P., Christensen, I. J., Brasso, K. & Røder, M. A., Feb 2016, In : Biomarkers in Medicine. 10, 2, p. 209-16 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published
  16. 2015
  17. Published

    TNF Receptor-2 Facilitates an Immunosuppressive Microenvironment in the Liver to Promote the Colonization and Growth of Hepatic Metastases

    Ham, B., Wang, N., D'Costa, Z., Fernandez, M. C., Bourdeau, F., Auguste, P., Illemann, M., Eefsen, R. L., Høyer-Hansen, G., Vainer, B., Evrard, M., Gao, Z-H. & Brodt, P., 15 Dec 2015, In : Cancer Research. 75, 24, p. 5235-47 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Intact and cleaved plasma soluble urokinase receptor in patients with metastatic colorectal cancer treated with oxaliplatin with or without cetuximab

    Tarpgaard, L. S., Christensen, I. J., Høyer-Hansen, G., Lund, I. K., Guren, T. K., Glimelius, B., Sorbye, H., Tveit, K. M., Nielsen, H. J., Moreira, J. M. A., Pfeiffer, P. & Brünner, N., 15 Nov 2015, In : International journal of cancer. Journal international du cancer. 137, 10, p. 2470-77

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Inflammation and uPAR-Expression in Colorectal Liver Metastases in Relation to Growth Pattern and Neo-adjuvant Therapy

    Eefsen, R. L., Engelholm, L., Alpizar-Alpizar, W., Van den Eynden, G. G. E., Vermeulen, P. B., Christensen, I. J., Laerum, O. D., Rolff, H. C., Høyer-Hansen, G., Vainer, B., Osterlind, K. & Illemann, M., 14 Aug 2015, In : Cancer Microenvironment. 8, 2, p. 93-100

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Growth pattern of colorectal liver metastasis as a marker of recurrence risk

    Eefsen, R. L., Vermeulen, P. B., Christensen, I. J., Laerum, O. D., Mogensen, M. B., Rolff, H. C., Van den Eynden, G. G., Høyer-Hansen, G., Osterlind, K., Vainer, B. & Illemann, M., Apr 2015, In : Clinical & experimental metastasis. 32, 4, p. 369-81 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published
  22. Published
  23. Published

    Reduction of mouse atherosclerosis by urokinase inhibition or with a limited-spectrum matrix metalloproteinase inhibitor

    Hu, J. H., Touch, P., Zhang, J., Wei, H., Liu, S., Lund, I. K., Høyer-Hansen, G. & Dichek, D. A., 2015, In : Cardiovascular Research. 105, p. 372-382

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published
  25. 2014
  26. Published

    Positron emission tomography/computed tomography for optimized colon cancer staging and follow up

    Engelmann, B., Loft, A., Kjær, A., Nielsen, H. J., Berthelsen, A. K., Binderup, T., Brinch, K., Brünner, N. A., Gerds, T. A., Høyer-Hansen, G., Kristensen, M. H., Kurt, E. Y., Latocha, J. E., Lindblom, G., Sloth, C. & Højgaard, L., 29 Nov 2014, In : Scandinavian Journal of Gastroenterology. 49, 2, p. 191-201

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Tumor stromal phenotypes define VEGF sensitivity-letter

    Van den Eynden, G. G., Bird, N. C., Dirix, L. Y., Eefsen, R. L., Gao, Z-H., Høyer-Hansen, G., Illemann, M., Majeed, A. W., Metrakos, P., Reynolds, A. R., Vainer, B., van Dam, P-J., Van Laere, S. J., Vermeulen, P. B., Vidal-Vanaclocha, F., Brodt, P. & Liver Metastasis Research Network, 1 Oct 2014, In : Clinical Cancer Research. 20, 19, p. 5140

    Research output: Contribution to journalLetterResearch

  28. Published

    Urokinase-type plasminogen activator receptor (uPAR) on tumor-associated macrophages is a marker of poor prognosis in colorectal cancer

    Illemann, M., Laerum, O. D., Hasselby, J. P., Sørensen, T. T., Høyer-Hansen, G., Nielsen, H. J., Christensen, I. J. & the Danish Study Group on Early Detection of Colorectal Cancer, 1 Aug 2014, In : C M E Cancer Medicine. 3, 4, p. 855 864 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published
  30. 2013
  31. Published

    Allosteric Inactivation of a Trypsin-Like Serine Protease by An Antibody Binding to the 37- and 70-Loops

    Kromann-Hansen, T., Lund, I. K., Liu, Z., Andreasen, P. A., Høyer-Hansen, G. & Sørensen, H. P., 30 Sep 2013, In : Biochemistry. 52, 40, p. 7114-26

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP. Impact on lymphangiogenesis

    Ingvarsen, S., Porse, A., Erpicum, C., Maertens, L., Jürgensen, H. J., Madsen, D. H., Carlsen Melander, E. M., Gårdsvoll, H., Høyer-Hansen, G., Noel, A., Holmbeck, K., Engelholm, L. H. & Behrendt, N., 12 Apr 2013, In : Journal of Biological Chemistry. 288, 15, p. 10195-204

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    The multifaceted role of the microenvironment in liver metastasis: biology and clinical implications

    Van den Eynden, G. G., Majeed, A. W., Illemann, M., Vermeulen, P. B., Bird, N. C., Høyer-Hansen, G., Eefsen, R. L., Reynolds, A. R. & Brodt, P., 1 Apr 2013, In : Cancer Research. 73, 7, p. 2031-43 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Differences of macrophage and T cell infiltration in colorectal liver metastases

    Eefsen, R. L., Alpizar, W. E. A., Høyer-Hansen, G., Christensen, I. J., Engelholm, L. H., Lærum, O. D., Vainer, B. & Illemann, M., 2013, In : APMIS Supplementum. 121, S 135, p. 16

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  35. Published
  36. 2012
  37. Published

    Bone marrow-derived myofibroblasts are the providers of pro-invasive matrix metalloproteinase 13 in primary tumor

    Lecomte, J., Masset, A., Blacher, S., Maertens, L., Gothot, A., Delgaudine, M., Bruyère, F., Carnet, O., Paupert, J., Illemann, M., Foidart, J-M., Lund, I. K., Høyer-Hansen, G. & Noel, A., 2012, In : Neoplasia. 14, 10, p. 943-51 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published
  39. Published
  40. Published

    Interconversion of active and inactive conformations of urokinase-type plasminogen activator

    Liu, Z., Kromann-Hansen, T., Lund, I. K., Hosseini, M., Jensen, K. J., Høyer-Hansen, G., Andreasen, K. P. & Sørensen, H. P., 2012, In : Biochemistry. 51, 39, p. 7804-11 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    New and paradoxical roles of matrix metalloproteinases in the tumor microenvironment

    Noël, A., Gutiérrez-Fernández, A., Sounni, N. E., Behrendt, N., Maquoi, E., Lund, I. K., Cal, S., Hoyer-Hansen, G. & López-Otín, C., 2012, In : Frontiers in Pharmacology. 3, p. 140

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Phase II trial of erlotinib and bevacizumab in patients with advanced upper gastrointestinal cancers

    Rohrberg, K. S., Olesen, R. K., Pfeiffer, P., Ladekarl, M., Pappot, H., Christensen, I. J., Høyer-Hansen, G., Sørensen, M., Skov, B. G., Buysschaert, I., Carmeliet, P. & Lassen, U., 2012, In : Acta Oncologica. 51, 2, p. 234-42 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Urokinase-Type Plasminogen Activator, Its receptor and Inhibitor as Biomarkers in Cancer.

    Sørensen, T. T., Illemann, M., Christensen, I. J. & Høyer-Hansen, G., 2012, Matrix Proteases in Health and Disease. Wiley-VCH, p. 325-344

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  44. 2011
  45. Published

    Urokinase receptor forms in serum from non-small cell lung cancer patients: relation to prognosis

    Almasi, C. E., Christensen, I. J., Høyer-Hansen, G., Danø, K., Pappot, H., Dienemann, H. & Muley, T., Dec 2011, In : Lung Cancer. 74, 3, p. 510-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published
  47. Published

    Soluble urokinase plasminogen activator receptor during allogeneic stem cell transplantation

    Haastrup, E., Andersen, J., Ostrowski, S. R., Høyer-Hansen, G., Jacobsen, N., Heilmann, C., Ullum, H. & Müller, K., 1 Apr 2011, In : Scandinavian Journal of Immunology. 73, 4, p. 325-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Soluble urokinase plasminogen activator receptor as a prognostic marker in men participating in prostate cancer screening

    Kjellman, A., Akre, O., Gustafsson, O., Høyer-Hansen, G., Lilja, H., Norming, U., Piironen, T. & Törnblom, M., 2011, In : Journal of Internal Medicine. 269, 3, p. 299-305 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published
  50. 2010
  51. Published
  52. Published
  53. Published
  54. Published

    Does plasminogen activator inhibitor-1 drive lymphangiogenesis?

    Bruyère, F., Melen-Lamalle, L., Blacher, S., Detry, B., Masset, A., Lecomte, J., Lambert, V., Maillard, C., Høyer-Hansen, G., Lund, L. R., Foidart, J-M. & Noël, A., 1 Jan 2010, In : P L o S One. 5, 3, p. e9653

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published
  56. Published

    Neutralisation of uPA with a monoclonal antibody reduces plasmin formation and delays skin wound healing in tPA-deficient mice

    Jögi, A., Rønø, B., Lund, I. K., Nielsen, B. S., Ploug, M., Høyer-Hansen, G., Nielsen, J. R. & Lund, L. R., 1 Jan 2010, In : P L o S One. 5, 9, p. e12746

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Soluble urokinase-type plasminogen activator receptor forms in plasma as markers of atherosclerotic plaque vulnerability

    Olson, F. J., Sørensen, T. T., Ryndel, M., Høyer-Hansen, G. & Fagerberg, B., 1 Jan 2010, In : Clinical Biochemistry. 43, 1-2, p. 124-30 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. 2008
  59. Published
  60. 2007
  61. Published

    Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation

    Madsen, D. H., Engelholm, L. H., Ingvarsen, S., Hillig, T., Wagenaar-Miller, R. A., Kjøller, L., Gårdsvoll, H., Høyer-Hansen, G., Holmbeck, K., Bugge, T. H. & Behrendt, N., 14 Sep 2007, In : The journal of biological chemistry. 282, 37, p. 27037-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Elevated plasma urokinase receptor predicts low birth weight in maternal malaria

    Ostrowski, S. R., Shulman, C. E., Peshu, N., Staalsøe, T., Høyer-Hansen, G., Pedersen, B. K., Marsh, K. & Ullum, H., Jan 2007, In : Parasite Immunology. 29, 1, p. 37-46 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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