Gro Linno Willemoe

Research output

Research output per year 2010 2018 2020 2021 2022 2023

• 27 Journal article
• 3 Conference abstract for conference
• 2 Poster
• 1 Conference abstract in journal
• 1 More
  • 1 Other contribution

Research output per year

Research output per year

Search results

• 2023

  Pre-existing TGF-β-specific T-cell immunity in patients with pancreatic cancer predicts survival after checkpoint inhibitors combined with radiotherapy

  Mortensen, R. E. J., Holmström, M. O., Lisle, T. L., Hasselby, J. P., Willemoe, G. L., Met, Ö., Marie Svane, I., Johansen, J., Nielsen, D. L., Chen, I. M. & Andersen, M. H., 22 Mar 2023, In: Journal for ImmunoTherapy of Cancer. 11, 3, e006432.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Transforming Growth Factors 100%
  • Pancreatic Neoplasms 90%
  • Immunity 77%
  • Radiotherapy 65%
  • T-Lymphocytes 58%
  1 Citation (Scopus)

• Salvage therapies of autoimmune hepatitis limit proinflammatory immune cells while sparing regulatory T cells

  Derben, F. C., Ytting, H., Hartleben, B., Bantel, H., Wedemeyer, H., Willemoe, G. L., Jaeckel, E. & Taubert, R., 1 Apr 2023, In: Hepatology communications. 7, 4

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Autoimmune Hepatitis 100%
  • Salvage Therapy 93%
  • Regulatory T-Lymphocytes 78%
  • B-Lymphocytes 32%
  • T-Lymphocytes 26%
• 2022

  Differences in gene expression despite identical histomorphology in sinonasal intestinal type adenocarcinoma and metastases from colorectal adenocarcinoma

  Sjöstedt, S., Vieira, F. G., Karnov, K., Agander, T. K., Willemoe, G. L., Rohrberg, K. S., Nielsen, F. C. & von Buchwald, C., Sep 2022, In: APMIS - Journal of Pathology, Microbiology and Immunology. 130, 9, p. 551-559 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Adenocarcinoma 100%
  • Neoplasm Metastasis 78%
  • Gene Expression 76%
  • Staining and Labeling 24%
  • Biomarkers 16%

• Extensive genomic analysis in patients with KRAS-mutated solid tumors shows high frequencies of concurrent alterations and potential targets but has limited clinical impact

  Jacobsen, I. C., Spanggaard, I., Højgaard, M., Belcaid, L., Qvortrup, C., Yde, C. W., Schmidt, A. Y., Nielsen, F. C., Willemoe, G. L., Dam, M. S., Lassen, U. & Staal Rohrberg, K., Dec 2022, In: Acta Oncologica. 61, 12, p. 1499-1506 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Synthetic Lethal Mutations 100%
  • Synthetic Drugs 93%
  • Neoplasms 87%
  • Codon 67%
  • Immunotherapy 59%

• Noninvasive Prediction of Advanced Fibrosis in Pediatric Liver Disease-Discriminatory Performance of 2D Shear Wave Elastography, Transient Elastography and Magnetic Resonance Elastography in Comparison to Histopathology

  Nielsen, J., Kjær, M. S., Rasmussen, A., Chiranth, D., Willemoe, G. L., Henriksen, B. M., Borgwardt, L., Grand, M. K., Borgwardt, L. & Christensen, V. B., 2022, In: Diagnostics. 12, 11, 16 p., 2785.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Elasticity Imaging Techniques 100%
  • Magnetic Resonance 85%
  • Wave 76%
  • Shear 74%
  • Liver Diseases 69%

• Randomized Phase II Study of Nivolumab With or Without Ipilimumab Combined With Stereotactic Body Radiotherapy for Refractory Metastatic Pancreatic Cancer (CheckPAC)

  Chen, I. M., Johansen, J. S., Theile, S., Hjaltelin, J. X., Novitski, S. I., Brunak, S., Hasselby, J. P., Willemoe, G. L., Lorentzen, T., Madsen, K., Jensen, B. V., Wilken, E. E., Geertsen, P., Behrens, C., Nolsoe, C., Hermann, K. L., Svane, I. M. & Nielsen, D., 20 Sep 2022, In: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40, 27, p. 3180-3189 10 p., JCO.21.02511.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Ipilimumab 100%
  • Nivolumab 96%
  • Radiosurgery 78%
  • Pancreatic Neoplasms 67%
  • Response Evaluation Criteria in Solid Tumors 7%
• 2021

  Clinical assessment of tumor regression grade systems in gastroesophageal adenocarcinoma following neoadjuvant chemotherapy

  Lütken, C., Sheikh, K., Willemoe, G. L., Achiam, M. P. & Hasselby, J. P., Aug 2021, In: Pathology, research and practice. 224, 153538.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Adenocarcinoma 100%
  • Drug Therapy 75%
  • Neoplasms 41%
  • Neoadjuvant Therapy 21%
  • Consultants 19%

• Correction to: Major driver mutations are shared between sinonasal intestinal-type adenocarcinoma and the morphologically identical colorectal adenocarcinoma (Journal of Cancer Research and Clinical Oncology, (2020), 10.1007/s00432-020-03421-5)

  Sjöstedt, S., Schmidt, A. Y., Vieira, F. G., Willemoe, G. L., Agander, T. K., Olsen, C., Nielsen, F. C. & von Buchwald, C., Apr 2021, 1029 p.

  Research output: Other contribution › Research

  • Medical Oncology 100%
  • Nasal Cavity 95%
  • Colorectal Neoplasms 67%
  • Adenocarcinoma 66%
  • Neoplasm Metastasis 52%

• Increase of Ki-67 index and influence on mortality in patients with neuroendocrine neoplasms

  Holmager, P., Langer, S. W., Federspiel, B., Willemoe, G. L., Garbyal, R. S., Melchior, L., Klose, M., Kjaer, A., Hansen, C. P., Andreassen, M. & Knigge, U., Sep 2021, In: Journal of Neuroendocrinology. 33, 9, p. e13018 e13018.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Mortality 100%
  • Neoplasm Metastasis 70%
  • Disease Progression 67%
  • Neoplasms 64%
  • Therapeutics 4%
  6 Citations (Scopus)

• IRDye800CW labeled uPAR-targeting peptide for fluorescence-guided glioblastoma surgery: Preclinical studies in orthotopic xenografts

  Kurbegovic, S., Juhl, K., Sørensen, K. K., Leth, J., Willemoe, G. L., Christensen, A., Adams, Y., Jensen, A. R., von Buchwald, C., Skjøth-Rasmussen, J., Ploug, M., Jensen, K. J. & Kjaer, A., 2021, In: Theranostics. 11, 15, p. 7159-7174 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Urokinase Plasminogen Activator Receptors 100%
  • Glioblastoma 70%
  • Heterografts 64%
  • Fluorescence 58%
  • Blood-Brain Barrier 55%

• Liver fibrosis in patients with tetralogy of Fallot, an unrecognised complication?

  Ravndal, M. E. H., Borgwardt, L., Juul, K., Nielsen, J., Borgwardt, L., Henriksen, B. M., Willemoe, G. L., Jensen, A. S., Christensen, V. B. & Kjær, M. S., Nov 2021, In: Cardiology in the Young. 31, 11, p. 1796-1806 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Tetralogy of Fallot 100%
  • Liver Cirrhosis 75%
  • Central Venous Pressure 45%
  • Liver Diseases 31%
  • Elasticity Imaging Techniques 27%

• Major driver mutations are shared between sinonasal intestinal-type adenocarcinoma and the morphologically identical colorectal adenocarcinoma

  Sjöstedt, S., Schmidt, A. Y., Vieira, F. G., Willemoe, G. L., Agander, T. K., Olsen, C., Nielsen, F. C. & von Buchwald, C., Apr 2021, In: Journal of Cancer Research and Clinical Oncology. 147, 4, p. 1019-1027 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Adenocarcinoma 100%
  • Mutation 71%
  • Neoplasm Genes 18%
  • DNA Sequence Analysis 17%
  • Neoplasms 13%
  8 Citations (Scopus)

• Neuroendocrine neoplasms of the appendix: Characterization of 335 patients referred to the Copenhagen NET Center of Excellence

  Holmager, P., Willemoe, G. L., Nielsen, K., Grøndahl, V., Klose, M., Andreassen, M., Langer, S. W., Hansen, C. P., Kjær, A., Federspiel, B. H. & Knigge, U., Jun 2021, In: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 47, 6, p. 1357-1363 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Lymph Nodes 100%
  • Colectomy 93%
  • Neoplasm Metastasis 86%
  • Neoplasms 72%
  • Medical Overuse 68%
• 2020

  A rare missense variant in APC interrupts splicing and causes AFAP in two Danish families

  Djursby, M., Wadt, K., Frederiksen, J. H., Madsen, M. B., Berchtold, L. A., Hasselby, J. P., Willemoe, G. L., Hansen, T. V. O. & Gerdes, A-M., 7 Apr 2020, In: Hereditary Cancer in Clinical Practice. 18, 1, p. 1-6 6 p., 8.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Caroli Disease 100%
  • Exons 38%
  • Attenuated familial adenomatous polyposis 28%
  • Mucinous Cystadenocarcinoma 24%
  • Liver 24%
  2 Citations (Scopus)

• Hepatic epitheloid haemangioendothelioma: a rare malignant tumour

  Lund, P. S., Willemoe, G. L., Hansen, L. B. & Warnecke, M., 28 Jan 2020, In: BMJ Case Reports . 13, 1, e232794.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Hemangioendothelioma 100%
  • Gastroscopy 43%
  • Cholangiocarcinoma 39%
  • Hemangioma 36%
  • Liver 35%
  1 Citation (Scopus)

• New Pathogenic Germline Variants in Very Early Onset and Familial Colorectal Cancer Patients

  Djursby, M., Madsen, M. B., Frederiksen, J. H., Berchtold, L. A., Therkildsen, C., Willemoe, G. L., Hasselby, J. P., Wikman, F., Okkels, H., Skytte, A-B., Nilbert, M., Wadt, K., Gerdes, A-M. & van Overeem Hansen, T., 24 Sep 2020, In: Frontiers in genetics. 11, p. 566266 566266.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Colorectal Neoplasms 100%
  • Neoplasm Genes 68%
  • Hereditary Neoplastic Syndromes 31%
  • Neoplasms 27%
  • Genes 25%
  10 Citations (Scopus)

• Peroxisome proliferator-activated receptor activity correlates with poor survival in patients resected for hepatocellular carcinoma

  Pommergaard, H-C., Preuss Hasselby, J., Linno Willemoe, G., Ralbovska, A., Arendtsen Rostved, A., Rasmussen, A., Aagaard Schultz, N., Hillingsø, J., Nørgaard Larsen, P. & Kugler, J-M., 2 May 2020, In: Journal of Hepato-Biliary-Pancreatic Sciences.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Peroxisome Proliferator-Activated Receptors 100%
  • Hepatocellular Carcinoma 66%
  • Survival 45%
  • RNA Sequence Analysis 30%
  • Margins of Excision 29%

• The macrophage activation marker soluble CD163 is elevated and associated with liver disease phenotype in patients with Wilson's disease

  Glavind, E., Gotthardt, D. N., Pfeiffenberger, J., Sandahl, T. D., Bashlekova, T., Willemoe, G. L., Hasselby, J. P., Weiss, K. H., Møller, H. J., Vilstrup, H., Lee, W. M., Schilsky, M. L., Ott, P. & Grønbæk, H., 2 Jul 2020, In: Orphanet Journal of Rare Diseases. 15, 1, p. 173 173.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Hepatolenticular Degeneration 100%
  • Macrophage Activation 88%
  • Liver Diseases 65%
  • Phenotype 46%
  • Acute Liver Failure 41%
  5 Citations (Scopus)
• 2019

  Intrapancreatic accessory spleen mimicking malignant tumor: three case reports

  Zurek Munk-Madsen, M., Zakarian, K., Sandor Oturai, P., Hansen, C. P., Federspiel, B., Fallentin, E. & Linno Willemoe, G., Jun 2019, In: Acta Radiologica Open. 8, 6, p. e1-5

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Spleen 100%
  • Neuroendocrine Tumors 96%
  • Sodium Pertechnetate Tc 99m 58%
  • Neoplasm Metastasis 52%
  • Single-Photon Emission-Computed Tomography 43%
• 2018

  Assessment Of The Correlation Between Dynamic Contrast Enhanced Computed Tomography And Histological And Vascular Biomarkers In Patients Resected For Colorectal Liver Metastases

  Lauridsen, C. A., Axelsen, T., Hansen, M. L., Fallentin, E. M., Bachmann Nielsen, M., Eefsen, R. L., Illemann, M., Engelholm, L. H., Vainer, B., Høyer-Hansen, G., Lund, I. K., Willemoe, G. L., Rolff, H. C., Mogensen, M. B. & Østerlind, K. E., 2018, In: Imaging in Medicine. 10, 6, p. 147-154

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Perfusion Index 100%
  • Microvessels 92%
  • Plasminogen 81%
  • Tomography 78%
  • Urokinase-Type Plasminogen Activator 78%

• detection of microsatellite instability (MSI) in colorectal cancer samples with a novel set of highly sensitive markers by means of the idylla MSI test prototype

  De Craene, B., Van de Velde, J., Rondelez, E., Vandenbroeck, L., Peeters, K., Vanhoey, T., Elsen, N., Vandercruyssen, G., Melchior, L. C., Willemoe, G. L., Jones, A., Hongxiang, L., Henrique, R., Teixeira, M., Zhao, H., Lambrechts, D., Decanniere, K., Sablon, E. & Maertens, G. G., 2018.

  Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  • Microsatellite Instability 100%
  • Colorectal Neoplasms 64%
  • Promega 33%
  • Microsatellite Repeats 28%
  • Formaldehyde 12%

• Detection of microsatellite instability (msi) with a novel set of 7 idylla biomarkers on colorectal cancer samples in a multi-center study

  De Craene, B., Van de Velde, J., Gazin, M., Rondelez, E., Vandenbroeck, L., Vanhoey, T., Elsen, N., Melchior, L. C., Willemoe, G. L., Watkin, E., Arens, N., Altmann, C., Decanniere, K., Sablon, E. & Maertens, G. G., 2018.

  Research output: Contribution to conference › Poster › Research › peer-review

  • Microsatellite Instability 100%
  • Colorectal Neoplasms 64%
  • Biomarkers 53%
  • Promega 36%
  • DNA Mismatch Repair 17%

• Medical Evaluation of Non-Alcoholic Steatohepatitis (NASH) Real-World outcome from a Community NASH Clinic in Denmark

  Ebrahim, M., Schiødt, F. V., Willemoe, G. L., Dahl, E. E., Christensen, E., Rashid, S., Holm, O., Olsen, A. M. Z., Heitmann, M. & Hansen, M. B., 2018.

  Research output: Contribution to conference › Poster › Research › peer-review

• Neuroendocrine Neoplasms of the Appendix: Characterization of 251 Patients Referred to the Copenhagen NET Centre of Excellence

  Holmager, P., Willemoe, G. L., Nielsen, K., Grøndahl, V., Andreassen, M., Langer, S. W., Hansen, C. P., Kjær, A., Federspiel, B. H. & Knigge, U., 2018.

  Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  • Appendix 100%
  • Appendiceal Neoplasms 40%
  • Goblet Cells 30%
  • Lost to Follow-Up 27%
  • Neoplasms 24%

• Quantitative perfusion assessment of intestinal anastomoses in pigs treated with glucagon-like peptide 2

  Nerup, N., Ring, L. L., Strandby, R. B., Egeland, C., Svendsen, M. B. S., Hasselby, J. P., Willemoe, G. L., Hartmann, B., Svendsen, L. B. & Achiam, M. P., 2018, In: Langenbecks Archives of Surgery. 403, 7, p. 881-889

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Glucagon-Like Peptide 2 100%
  • Swine 50%
  • Perfusion 47%
  • Placebos 14%
  • Anastomotic Leak 8%
  9 Citations (Scopus)
• 2016

  Colonic perforation following endoscopic mucosal resection in a patient on bevacizumab treatment

  Kalaitzakis, E., Havre, R. F., Willemoe, G. L. & Meisner, S., 2016, In: Endoscopy. 48 Suppl 1, p. E224-5

  Research output: Contribution to journal › Journal article › Research › peer-review

  1 Citation (Scopus)

• Double Immunohistochemical staining with laminin 5 (Y2 chain) and collagen IV in colorectal neoplasms

  Kanstrup, A-M. F., Bzorek, M., Warnecke, M., Vainer, B. & Willemoe, G. L., 2016, In: International journal of clinical experimental pathology. 9, 12, p. 12866-75

  Research output: Contribution to journal › Journal article › Research › peer-review

• Microvessel density and endothelial cell proliferation levels in colorectal liver metastases from patients given neo-adjuvant cytotoxic chemotherapy and bevacizumab

  Eefsen, R. L., Engelholm, L., Willemoe, G. L., Van den Eynden, G. G. G., Laerum, O. D., Christensen, I. J., Rolff, H. C., Høyer-Hansen, G., Osterlind, K., Vainer, B. & Illemann, M., 1 Apr 2016, In: International journal of cancer. Journal international du cancer. 138, 7, p. 1777-1784

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Bevacizumab 100%
  • Adjuvant Chemotherapy 90%
  • Microvessels 90%
  • Endothelial Cells 66%
  • Cell Proliferation 59%
  19 Citations (Scopus)
• 2015

  Medullary carcinoma of the colon: can the undifferentiated be differentiated?

  Kanstrup, A-M. F., Grauslund, M., Glenthøj, A., Melchior, L. C., Vainer, B. & Willemoe, G. L., Jan 2015, In: Virchows Archiv : an international journal of pathology. 466, 1, p. 13-20 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Medullary Carcinoma 100%
  • Colon 56%
  • Adenocarcinoma 55%
  • Mutation Rate 30%
  • Pathologists 13%
  14 Citations (Scopus)
• 2013

  Systemic Mastocytosis in Gastrointestinal Biopsies

  Willemoe, G. L. & Stovgaard, E. I. S., 2013, In: APMIS Supplementum. 121, S 135, p. 21

  Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
• 2012

  Histopathological growth pattern, proteolysis and angiogenesis in chemonaive patients resected for multiple colorectal liver metastases

  Eefsen, R. L., Van den Eynden, G. G., Høyer-Hansen, G., Brodt, P., Laerum, O. D., Vermeulen, P. B., Christensen, I. J., Wettergren, A., Federspiel, B., Willemoe, G. L., Vainer, B., Osterlind, K. & Illemann, M., 2012, In: International Journal of Oncology. 2012, p. 907971

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Proteolysis 100%
  • Neoplasm Metastasis 65%
  • Liver 54%
  • Growth 53%
  • Urokinase Plasminogen Activator Receptors 11%
  50 Citations (Scopus)
• 2010

  Accessory diaphragm. A case of a peculiar rare malformation

  Maroun, L. L. & Willemoe, G. L., 2010.

  Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

• AMACR is not applicable as a diagnostic tool in hepatocellular carcinoma

  Willemoe, G. L. & Vainer, B., 1 Feb 2010, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 118, 2, p. 85-90 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Hepatocellular Carcinoma 100%
  • Staining and Labeling 80%
  • Racemases and Epimerases 37%
  • Neoplasms 32%
  • Coenzyme A 30%
  1 Citation (Scopus)

  22 Downloads (Pure)

• HER2, TOP2A, and TIMP-1 and responsiveness to adjuvant anthracycline-containing chemotherapy in high-risk breast cancer patients

  Ejlertsen, B., Jensen, M-B., Nielsen, K., Balslev, E., Rasmussen, B., Willemoe, G. L., Hertel, P. B., Knoop, A. S., Mouridsen, H. T. & Brünner, N. A., 20 Feb 2010, In: Journal of Clinical Oncology. 28, 6, p. 984-90 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Tissue Inhibitor of Metalloproteinase-1 100%
  • Anthracyclines 95%
  • Fluorouracil 58%
  • Cyclophosphamide 56%
  • Breast Neoplasms 53%
  62 Citations (Scopus)