Giedrius Lelkaitis

2025

Feasibility of 3D ultrasound for intraoperative tumor margin assessment in transoral robotic surgery for oropharyngeal squamous cell carcinoma: A pilot study

Garset-Zamani, M., Makouei, F., Agander, T. K., Lelkaitis, G., Charabi, B. W., Tvedskov, J. F., Rubek, N., Lomholt, A. F., Frehr, T. D., Norling, R., Buchwald, C. V. & Todsen, T., 29 Apr 2025, (E-pub ahead of print) In: Oral Oncology. 165, p. 107330 107330.

Research output: Contribution to journal › Journal article › Research › peer-review

Optical molecular imaging in oral- and oropharyngeal squamous cell carcinoma using a novel uPAR-targeting near-infrared imaging agent FG001 (ICG-Glu-Glu-AE105): An explorative phase II clinical trial

Andersen, A. O., Christensen, A., Straede, K., Lawaetz, M., Hahn, C. H., Rubek, N., Wessel, I., Lelkaitis, G., Kiss, K., Paaske, N., Poulsen, A., von Buchwald, C. & Kjaer, A., 2025, In: Theranostics. 15, 1, p. 52-67 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

2024

Epidemiology and treatment outcome of nasopharyngeal carcinoma in a low-incidence population - a DAHANCA analysis in Denmark 2000-2018

Schiess, E., Jensen, K. H., Kristensen, M. H., Johansen, J., Eriksen, J. G., Maare, C., Andersen, M., Farhadi, M., Hansen, C. R., Overgaard, J., Hjalgrim, L. L., Lelkaitis, G. & Friborg, J., 4 Nov 2024, In: Acta Oncologica. 63, p. 850-857 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Feasibility and diagnostic performance of sentinel node biopsy for staging cN0 oral squamous cell carcinoma in a previously treated neck

Mørch, T., Tvedskov, J. F., Wessel, I., Charabi, B. W., Jakobsen, K. K., Grønhøj, C., Kiss, K., Lelkaitis, G., Mortensen, J., Kjaer, A., von Buchwald, C. & Christensen, A., Dec 2024, In: World journal of otorhinolaryngology - head and neck surgery. 10, 4, p. 261-269 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Feasibility of a Novel 3D Ultrasound Imaging Technique for Intraoperative Margin Assessment during Tongue Cancer Surgery

Makouei, F., Frehr, T. D., Agander, T. K., Lelkaitis, G., Hyldig Dal, M., Kaltoft, M., Orloff, L., Sebelik, M., Søndergaard Svendsen, M. B., Wessel, I. & Todsen, T., 1 Aug 2024, In: Current oncology (Toronto, Ont.). 31, 8, p. 4414-4431 18 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Urokinase Plasminogen Activator Receptor: An Important Focal Player in Chronic Subdural Hematoma?

Jensen, T. S. R., Olsen, M. H., Lelkaitis, G., Kjaer, A., Binderup, T. & Fugleholm, K., Jun 2024, In: Inflammation. 47, 3, p. 1015-1027 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

2023

Diagnostic accuracy of combined optical- and radio-guided SNB for neck staging of oral squamous cell carcinoma lesions in the anterior oral cavity

Christensen, A., Wessel, I., Charabi, B. W., Juhl, K., Kiss, K., Lelkaitis, G., Mortensen, J., Kjaer, A., von Buchwald, C. & Tvedskov, J. F., Jul 2023, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 280, 7, p. 3393-3403 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Diagnostic Value of Preoperative uPAR-PET/CT in Regional Lymph Node Staging of Oral and Oropharyngeal Squamous Cell Carcinoma: A Prospective Phase II Trial

Lawaetz, M., Christensen, A., Juhl, K., Lelkaitis, G., Karnov, K., Carlsen, E. A., Charabi, B. W., Loft, A., Czyzewska, D., Buchwald, C. V. & Kjaer, A., 25 Oct 2023, In: Diagnostics. 13, 21, 3303.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Effect of near infrared autofluorescence guided total thyroidectomy on postoperative hypoparathyroidism: a randomized clinical trial

Lykke, E., Christensen, A., Juhl, K., Feldt-Rasmussen, U., Friberg Hitz, M., Svenningsen Sjöstedt, S. M., Holst Hahn, C., Kraik Svensson, D. M., Kanstrup Springborg, K., Stage, M. G., Bjørn Hvilsom, G., Hilsted, L. M., Dahl, M., Lelkaitis, G., Kjaer, A., Homøe, P. & von Buchwald, C., May 2023, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 280, 5, p. 2593-2603 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Granular cell tumour of the breast: A case report

Pankratjevaite, L., Igbokwe, M. M., Benian, C. & Lelkaitis, G., 2023, In: Breast disease. 42, 1, p. 219-222 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Liquid Biopsies with Circulating Plasma HPV-DNA Measurements-A Clinically Applicable Surveillance Tool for Patients with HPV-Positive Oropharyngeal Cancer

Jakobsen, K. K., Bendtsen, S. K., Pallisgaard, N., Friborg, J., Lelkaitis, G., Grønhøj, C. & von Buchwald, C., 2 Oct 2023, In: Clinical Cancer Research. 29, 19, p. 3914-3923 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Potential of uPAR, αvβ6 Integrin, and Tissue Factor as Targets for Molecular Imaging of Oral Squamous Cell Carcinoma: Evaluation of Nine Targets in Primary Tumors and Metastases by Immunohistochemistry

Lawaetz, M., Christensen, A., Juhl, K., Karnov, K., Lelkaitis, G., Kanstrup Fiehn, A.-M., Kjaer, A. & von Buchwald, C., 14 Feb 2023, In: International Journal of Molecular Sciences. 24, 4, 3853.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Tumor volume definitions in head and neck squamous cell carcinoma - comparing PET/MRI and histopathology

Terzidis, E., Friborg, J., Vogelius, I., Lelkaitis, G., von Buchwald, C., Olin, A. B., Hjorth Johannesen, H., Malene Fischer, B., Wessel, I. & Rasmussen, J. H., 2023, In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 180, p. 1-8 8 p., 109484.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Urokinase-Type Plasminogen Activator Receptor (uPAR) Expression and [64Cu]Cu-DOTA-AE105 uPAR-PET/CT in Patient-Derived Xenograft Models of Oral Squamous Cell Carcinoma

Lawaetz, M., Binderup, T., Christensen, A., Juhl, K., Lelkaitis, G., Lykke, E., Knudsen, L., von Buchwald, C. & Kjaer, A., Dec 2023, In: Molecular Imaging and Biology. 25, 6, p. 1034-1044 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

2022

Diagnostic challenges of adenomyoepithelioma: A case report

Pankratjevaite, L., Lind, K., Mele, M. & Lelkaitis, G., 2022, In: Breast disease. 41, 1, p. 325-330 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Expression patterns of uPAR, TF and EGFR and their potential as targets for molecular imaging in oropharyngeal squamous cell carcinoma

Christensen, A., Grønhøj, C., Jensen, J. S., Lelkaitis, G., Kiss, K., Juhl, K., Charabi, B. W., Mortensen, J., Kjær, A. & Von Buchwald, C., Aug 2022, In: Oncology Reports. 48, 2, 147.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Spinal versus conventional fine needle for ultrasound-guided thyroid nodule biopsy: a protocol for a randomised clinical trial

Andersen, T. V., Bennedbæk, F. N., Pedersen, J., Rosenørn, M. R., Kiss, K., Lelkaitis, G., Andersen, L., Hegedüs, L., Lomholt, A. F., Hahn, C. H., Hvilsom, G. B., Homøe, P. & Todsen, T., 21 Jul 2022, In: Danish Medical Journal. 69, 8, A03220165.

Research output: Contribution to journal › Journal article › Research › peer-review

2021

Intratumor heterogeneity is biomarker specific and challenges the association with heterogeneity in multimodal functional imaging in head and neck squamous cell carcinoma

Rasmussen, J. H., Olin, A. B., Lelkaitis, G., Hansen, A. E., Andersen, F. L., Johannesen, H. H., Kjaer, A., Fischer, B. M., Specht, L., Bentzen, S. M., von Buchwald, C., Wessel, I. & Vogelius, I. R., Jun 2021, In: European Journal of Radiology. 139, p. 109668 109668.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Late migration of silicon as a complication to breast transplant rupture: Case report and literature review

Khakbaz, E., Lang, C., Lelkaitis, G. & Grønhøj, C., Aug 2021, In: International Journal of Surgery Case Reports. 85, p. 106241 106241.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Nasopharyngeal malignancies in Denmark diagnosed from 1980 to 2014

Grønlund, M. P., Jakobsen, K. K., Mirian, C., Grønhøj, C., Juul Nielsen, K., Charabi, B., Lelkaitis, G., Bentzen, J. & von Bucwald, C., Nov 2021, In: Oral Oncology. 122, p. 105583 105583.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

The Impact of Comorbidity on Survival in Patients With Head and Neck Squamous Cell Carcinoma: A Nationwide Case-Control Study Spanning 35 Years

Ruud Kjær, E. K., Jensen, J. S., Jakobsen, K. K., Lelkaitis, G., Wessel, I., von Buchwald, C. & Grønhøj, C., 17 Feb 2021, In: Frontiers in Oncology. 10, p. 617184 617184.

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

2020

Does multiparametric imaging with F-18-FDG-PET/MRI capture spatial variation in immunohistochemical cancer biomarkers in head and neck squamous cell carcinoma?

Rasmussen, J. H., Olin, A., Lelkaitis, G., Hansen, A. E., Andersen, F. L., Johannesen, H. H., Kjær, A., Vogelius, I. R., Specht, L., Bentzen, S. M., Wessel, I., von Buchwald, C. & Fischer, B. M., Jul 2020, In: British Journal of Cancer. 123, 1, p. 46-53 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

Impact of p16-overexpression on overall and progression-free survival outcomes in oral cavity squamous cell carcinomas: A semi-national, population-based study

Schneider, K., Jakobsen, K. K., Jensen, J. S., Wessel, I., Christensen, A., Specht, L., Lelkaitis, G., Mirian, C., Buchwald, C. V. & Grønhøj, C., Dec 2020, In: Oral Oncology. 111, p. 105031

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Outcome in patients with isolated regional recurrence after primary radiotherapy for head and neck cancer

Lindegaard, A. M., von Buchwald, C., Rasmussen, J. H., Specht, L., Vogelius, I. R., Zamani, M., Woller, N. C., Lelkaitis, G. & Friborg, J., 1 Nov 2020, In: Head and Neck. 42, 11, p. 3161-3170 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

2019

Intratumor heterogeneity of PD-L1 expression in head and neck squamous cell carcinoma

Rasmussen, J. H., Lelkaitis, G., Håkansson, K., Vogelius, I. R., Johannesen, H. H., Fischer, B. M., Bentzen, S. M., Specht, L., Kristensen, C. A., von Buchwald, C., Wessel, I. & Friborg, J., May 2019, In: British Journal of Cancer. 120, 10, p. 1003-1006 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

128 Citations (Scopus)

Near-infrared fluorescence imaging improves the nodal yield in neck dissection in oral cavity cancer - A randomized study

Christensen, A., Juhl, K., Kiss, K., Lelkaitis, G., Charabi, B. W., Mortensen, J., Kjær, A. & von Buchwald, C., Nov 2019, In: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 45, 11, p. 2151-2158 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Risk of Thyroid Cancer in 1,504 Patients Referred for Thyroid Surgery with Assumed Benign Histology

Gram, S. B., Rasmussen, J. H., Feldt-Rasmussen, U., Bentzen, J., Lelkaitis, G., von Buchwald, C. & Hahn, C. H., 1 Oct 2019, In: European Thyroid Journal. 8, 5, p. 246-255 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Risk profiling based on p16 and HPV DNA more accurately predicts location of disease relapse in patients with oropharyngeal squamous cell carcinoma

Rasmussen, J. H., Grønhøj, C., Håkansson, K., Friborg, J., Andersen, E., Lelkaitis, G., Klussmann, J. P., Wittekindt, C., Wagner, S., Vogelius, I. R. & von Buchwald, C., 1 Jan 2019, In: Annals of Oncology. 30, 4, p. 629-636 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

40 Citations (Scopus)

The Copenhagen Oral Cavity Squamous Cell Carcinoma database: protocol and report on establishing a comprehensive oral cavity cancer database

Schmidt Jensen, J., Jakobsen, K. K., Mirian, C., Christensen, J. T., Schneider, K., Nahavandipour, A., Wingstrand, V. L., Wessel, I., Tvedskov, J. F., Frisch, T., Christensen, A., Specht, L., Andersen, E., Lelkaitis, G., Grønhøj, C. & von Buchwald, C., 1 Jan 2019, In: Clinical Epidemiology. 11, p. 733-741 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

2018

Anaplastic thyroid carcinoma in Denmark 1996-2012: A national prospective study of 219 patients

Hvilsom, G. B., Londero, S. C., Hahn, C. H., Schytte, S., Pedersen, H. B., Christiansen, P., Kiss, K., Larsen, S. R., Jespersen, M. L., Lelkaitis, G. & Godballe, C., Apr 2018, In: Cancer epidemiology. 53, p. 65-71 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

32 Citations (Scopus)

An inter-observer Ki67 reproducibility study applying two different assessment methods: on behalf of the Danish Scientific Committee of Pathology, Danish breast cancer cooperative group (DBCG)

Laenkholm, A.-V., Grabau, D., Møller Talman, M.-L., Balslev, E., Bak Jylling, A. M., Tabor, T. P., Johansen, M., Brügmann, A., Lelkaitis, G., Di Caterino, T., Mygind, H., Poulsen, T., Mertz, H., Søndergaard, G. & Bruun Rasmussen, B., Jan 2018, In: Acta oncologica . 57, 1, p. 83-89 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

35 Citations (Scopus)

MicroRNA-based classifiers for diagnosis of oral cavity squamous cell carcinoma in tissue and plasma

Pedersen, N. J., Jensen, D. H., Lelkaitis, G., Kiss, K., Charabi, B. W., Ullum, H., Specht, L., Schmidt, A. Y., Nielsen, F. C. & von Buchwald, C., Aug 2018, In: Oral Oncology. 83, p. 46-52 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

42 Citations (Scopus)

Radioactive seed localisation of non-palpable lymph nodes - A feasibility study

Hassing, C. M. S., Tvedskov, T. F., Kroman, N., Klausen, T. L., Drejøe, J. B., Tvedskov, J. F., Lambine, T.-L., Kledal, H., Lelkaitis, G. & Langhans, L., May 2018, In: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 44, 5, p. 725-730 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

14 Citations (Scopus)

Standardized assessment of tumor-infiltrating lymphocytes in breast cancer: an evaluation of inter-observer agreement between pathologists

Tramm, T., Di Caterino, T., Jylling, A.-M. B., Lelkaitis, G., Lænkholm, A.-V., Ragó, P., Tabor, T. P., Talman, M.-L. M., Vouza, E. & Scientific Committee of Pathology, Danish Breast Cancer Group (DBCG), Jan 2018, In: Acta oncologica . 57, 1, p. 90-94 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

43 Citations (Scopus)

2017

Construction of a pathological risk model of occult lymph node metastases for prognostication by semi-automated image analysis of tumor budding in early-stage oral squamous cell carcinoma

Pedersen, N. J., Jensen, D. H., Lelkaitis, G., Kiss, K., Charabi, B., Specht, L. & von Buchwald, C., 14 Mar 2017, In: Oncotarget. 8, 11, p. 18227-18237 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

30 Citations (Scopus)

uPAR-targeted optical near-infrared (NIR) fluorescence imaging and PET for image-guided surgery in head and neck cancer: proof-of-concept in orthotopic xenograft model

Christensen, A., Juhl, K., Persson, M., Charabi, B. W., Mortensen, J., Kiss, K., Lelkaitis, G., Rubek, N., von Buchwald, C. & Kjær, A., 2017, In: Oncotarget. 8, p. 15407-15419

Research output: Contribution to journal › Journal article › Research › peer-review

48 Citations (Scopus)

Urokinase-type plasminogen activator receptor (uPAR), tissue factor (TF) and epidermal growth factor receptor (EGFR): tumor expression patterns and prognostic value in oral cancer

Christensen, A., Kiss, K., Lelkaitis, G., Juhl, K., Persson, M., Charabi, B. W., Mortensen, J., Forman, J. L., Sørensen, A. L., Jensen, D. H., Kjaer, A. & von Buchwald, C., 25 Aug 2017, In: B M C Cancer. 17, 1, p. 572

Research output: Contribution to journal › Journal article › Research › peer-review

31 Citations (Scopus)

2016

Intraoperative Sentinel Lymph Node Evaluation: Implications of Cytokeratin 19 Expression for the Adoption of OSNA in Oral Squamous Cell Carcinoma

Shaw, R., Christensen, A., Java, K., Maddani, R. E., Liloglou, T., Asterios, T., von Buchwald, C., Wessel, I., Kiss, K., Kjaer, A., Lelkaitis, G., Long, A., Risk, J. & Robinson, M., Nov 2016, In: Annals of Surgical Oncology. 23, 12, p. 4042-4048 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Staging of early lymph node metastases with the sentinel lymph node technique and predictive factors in T1/T2 oral cavity cancer: A retrospective single-center study

Pedersen, N. J., Jensen, D. H., Hedbäck, N., Frendø, M., Kiss, K., Lelkaitis, G., Mortensen, J., Christensen, A., Specht, L. & von Buchwald, C., 2016, In: Head & Neck (Print Edition). 38, Suppl 1, p. E1033-40

Research output: Contribution to journal › Journal article › Research › peer-review

69 Citations (Scopus)

2015

Diagnosis of bone metastasis from thyroid carcinoma: a multidisciplinary approach

Bechsgaard, T., Lelkaitis, G., Jensen, K. E. & Ewertsen, C., Nov 2015, In: Acta Radiologica Open. 4, 11, p. 2058460115603248

Research output: Contribution to journal › Journal article › Research › peer-review

Outcomes of special histotypes of breast cancer after adjuvant endocrine therapy with letrozole or tamoxifen in the monotherapy cohort of the BIG 1-98 trial

Munzone, E., Giobbie-Hurder, A., Gusterson, B. A., Mallon, E., Viale, G., Thürlimann, B., Ejlertsen, B., MacGrogan, G., Bibeau, F., Lelkaitis, G., Price, K. N., Gelber, R. D., Coates, A. S., Goldhirsch, A., Colleoni, M. & International Breast Cancer Study Group and the BIG 1-98 Collaborative Group, Dec 2015, In: Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 26, 12, p. 2442-9 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Giedrius Lelkaitis

Research output

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