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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2021
  2. Published
  3. Published

    Cellular Uptake and Intracellular Phosphorylation of GS-441524: Implications for Its Effectiveness against COVID-19

    Rasmussen, H. B., Jürgens, G., Thomsen, R., Taboureau, O., Zeth, K., Hansen, P. E. & Hansen, P. R., 14 Jul 2021, In: Viruses. 13, 7, 1369.

    Research output: Contribution to journalReviewResearchpeer-review

  4. 2020
  5. Published
  6. Published

    Pulmonary administration of remdesivir in the treatment of COVID-19

    Rasmussen, H. B., Hansen, P. R., Taboureau, O., Thomsen, R. & Jürgens, G., 1 Nov 2020, In: The AAPS journal. 22, 6, p. 121 121.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2019
  8. Published

    The impact of human CES1 genetic variation on enzyme activity assessed by ritalinic acid/methylphenidate ratios

    Stage, C., Dalhoff, K., Rasmussen, H. B., Thomsen, R., Bjerre, D., Ferrero-Miliani, L., Madsen, M. B. & Jürgens, G., Jul 2019, In: Basic & clinical pharmacology & toxicology. 125, 1, p. 54-61 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2017
  10. Published

    The prognosis following amphetamine poisoning

    Horwitz, H., Dalhoff, K. P., Klemp, M., Horwitz, A., Andersen, J. T. & Jürgens, G., Dec 2017, In: Scandinavian Journal of Public Health. Supplement. 45, 8, p. 773-781 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The impact of CES1 genotypes on the pharmacokinetics of methylphenidate in healthy Danish subjects

    Stage, C., Jürgens, G., Guski, L. S., Thomsen, R., Bjerre, D., Ferrero-Miliani, L., Lyauk, Y. K., Rasmussen, H. B., Dalhoff, K. & INDICES Consortium, Jul 2017, In: British Journal of Clinical Pharmacology. 83, 7, p. 1506-1514

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The Pharmacokinetics of Enalapril in Relation to CES1 Genotype in Healthy Danish Volunteers

    Stage, C., Jürgens, G., Guski, L. S., Thomsen, R., Bjerre, D., Ferrero-Miliani, L., Lyauk, Y. K., Rasmussen, H. B., Dalhoff, K., INDICES Consortium (for members of this consortium-see Supplementum) & INDICES consortium, Jul 2017, In: Basic & clinical pharmacology & toxicology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride

    Graudal, N. A., Hubeck-Graudal, T. & Jurgens, G., 9 Apr 2017, In: Cochrane Database of Systematic Reviews. 4, p. CD004022

    Research output: Contribution to journalReviewResearchpeer-review

  14. 2016
  15. Published

    Population Pharmacokinetics of Methylphenidate in Healthy Adults Emphasizing Novel and Known Effects of Several Carboxylesterase 1 (CES1) Variants

    Lyauk, Y. K., Stage, C., Bergmann, T. K., Ferrero-Milliani, L., Bjerre, D., Thomsen, R., Dalhoff, K. P., Rasmussen, H. B. & Jürgens, G., Dec 2016, In: Clinical and Translational Science. 9, 6, p. 337-345 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Clinical Pharmacology in Denmark in 2016 - 40 Years with the Danish Society of Clinical Pharmacology and 20 Years as a Medical Speciality

    Brøsen, K., Andersen, S. E., Borregaard, J., Christensen, H. R., Christensen, P. M., Dalhoff, K. P., Damkier, P., Hallas, J., Heisterberg, J., Jessen, N., Jürgens, G., Kampmann, J. P. K., Laursen, B. E., Laursen, T., Nielsen, L. P., Poulsen, B. K., Poulsen, H. E., Andersen, L. V., Senderovitz, T. & Sonne, J., 29 Sep 2016, In: Basic & clinical pharmacology & toxicology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Adverse Events Associated with Flumazenil Treatment for the Management of Suspected Benzodiazepine Intoxication - A Systematic Review with Meta-Analyses of Randomised Trials

    Penninga, E. I., Graudal, N., Ladekarl, M. B. & Jürgens, G., 28 Jul 2016, In: Basic & clinical pharmacology & toxicology. 118, 1, p. 37-44 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published
  19. Published

    Reduced Dietary Sodium Intake Increases Heart Rate. A Meta-Analysis of 63 Randomized Controlled Trials Including 72 Study Populations

    Graudal, N. A., Hubeck-Graudal, T. & Jürgens, G., 2016, In: Frontiers in Physiology. 7, p. e111

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2015
  21. Published
  22. Published

    Combination Therapy With and Without Tumor Necrosis Factor Inhibitors in Rheumatoid Arthritis: A Meta-Analysis of Randomized Trials

    Graudal, N., Hubeck-Graudal, T., Faurschou, M., Baslund, B. & Jürgens, G., Nov 2015, In: Arthritis Care & Research. 67, 11, p. 1487-95 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Levothyroxine Poisoning - Symptoms and Clinical Outcome

    Nygaard, B., Saedder, E. A., Dalhoff, K., Wikkelsoe, M. & Jürgens, G., Oct 2015, In: Basic & clinical pharmacology & toxicology. 117, 4, p. 280-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics

    Rasmussen, H. B., Bjerre, D., Linnet, K., Jürgens, G., Dalhoff, K., Stefansson, H., Hankemeier, T., Kaddurah-Daouk, R., Taboureau, O., Brunak, S., Houmann, T., Jeppesen, P., Pagsberg, A. K., Plessen, K., Dyrborg, J., Hansen, P. R., Hansen, P. E., Hughes, T., Werge, T., INDICES Consortium & Kaalund-Brok, K., 21 Apr 2015, In: Pharmacogenomics. 16, 6, p. 649-665 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    The significance of duration and amount of sodium reduction intervention in normotensive and hypertensive individuals: a meta-analysis

    Graudal, N., Hubeck-Graudal, T., Jürgens, G. & McCarron, D. A., Mar 2015, In: Advances in nutrition (Bethesda, Md.). 6, 2, p. 169-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Cannabismisbrug og dets konsekvenser

    Wøien, V-A., Horwitz, H., Høgberg, L. C. G., Askaa, B. & Jürgens, G., 2 Feb 2015, In: Ugeskrift for læger [online]. 177, 6

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Etanercept tapering in rheumatoid arthritis

    Graudal, N. & Jürgens, G., 29 Jan 2015, In: The New England journal of medicine. 372, 5, p. 489

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published
  29. 2014
  30. Published

    Der er interaktioner ved amfetaminmisbrug

    Horwitz, H., Skanning, P., Askaa, B. & Jürgens, G., 3 Nov 2014, In: Ugeskrift for Laeger. 176, 45

    Research output: Contribution to journalReviewResearchpeer-review

  31. Published

    Udviklingen fra lægemiddel til rusmiddel

    Askaa, B., Horwitz, H., Wøien, V. A., Høgberg, L. C. G. & Jürgens, G., 13 Oct 2014, In: Ugeskrift for læger [online]. 176, 42

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Compared with usual sodium intake, low- and excessive-sodium diets are associated with increased mortality: a meta-analysis

    Graudal, N., Jürgens, G., Baslund, B. & Alderman, M. H., Sep 2014, In: American Journal of Hypertension. 27, 9, p. 1129-37 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Metabolomics has the potential to improve drug therapy

    Stage, C., Jürgens, G., Dalhoff, K. P. & Rasmussen, H. B., 17 Mar 2014, In: Ugeskrift for læger [online]. 176, 6

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Atomoxetin til behandling af børn og unge med ADHD

    Resen, K., Pagsberg, A. K. & Jürgens, G., 3 Mar 2014, In: Ugeskrift for læger [online].

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Effect of combination therapy on joint destruction in rheumatoid arthritis: a network meta-analysis of randomized controlled trials

    Graudal, N., Hubeck-Graudal, T., Tarp, S., Christensen, R. & Jürgens, G., 2014, In: P L o S One. 9, 9, p. e106408

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published
  37. 2013
  38. Published

    Svimmelhed som bivirkning af farmakologisk behandling

    Borup Johansen, N., Ayadipanah, M., Sonnenschein, E. S., Christensen, H. R. & Jürgens, G., 4 Nov 2013, In: Ugeskrift for Laeger. 175, 45, p. 2720-5 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  39. Published
  40. Published

    Pregabalin kan medføre afhængighed og abstinenssymptomer

    Frederiksen, J. E. N. & Jürgens, G., 30 Sep 2013, In: Ugeskrift for Laeger. p. 1-2 2 p.

    Research output: Contribution to journalJournal articleCommissionedpeer-review

  41. Published
  42. Published

    A Case of Pregabalin Abuse

    Jürgens, G. & Frederiksen, J. E. N., 18 May 2013.

    Research output: Contribution to conferencePosterResearchpeer-review

  43. Published

    Does routine CYP2D6 and CYP2C19 genotyping reduce the risk of adverse events related to antipsychotic drug treatment?

    Jürgens, G., Andersen, S. E., Jensen, H., Rasmussen, H. B., Werge, T. M. & Nordentoft, M., 2013, In: Clinical Toxicology. 51, 4, p. 325-325 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  44. Published

    Genetic Schizophrenia Risk Variants Jointly Modulate Total Brain and White Matter Volume

    Terwisscha van Scheltinga, A. F., Bakker, S. C., van Haren, N. E. M., Derks, E. M., Buizer-Voskamp, J. E., Boos, H. B. M., Cahn, W., Hulshoff Pol, H. E., Ripke, S., Ophoff, R. A., Kahn, R. S. & the Psychiatric Genome-wide Association Study Consortium, 2013, In: Advances in Biological Psychiatry. 73, 6, p. 525-531

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    The level of the indication of biologic agents in the 2012 ACR recommendations on the treatment of Rheumatoid Arthritis

    Graudal, N. & Jürgens, G., 2013, In: Arthritis Care & Research. 65, 5, p. 832

    Research output: Contribution to journalComment/debateResearchpeer-review

  46. Published

    The (political) science of salt revisited

    Graudal, N. & Jürgens, G., 2013, In: BMJ. 346, p. f2741

    Research output: Contribution to journalJournal articleCommunication

  47. 2012
  48. Published

    A computerised sampling strategy for therapeutic drug monitoring of lithium provides precise estimates and significantly reduces dose-finding time

    Høgberg, L. C. G., Jürgens, G., Zederkof, V. W., Holgersson, B., Andersson, J. E., Dalhoff, K. P., Larsen, E. B. & Angelo, H. R., 2012, In: Basic & clinical pharmacology & toxicology. 110, 3, p. 259-63 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published
  50. Published

    Effect of golimumab combined with methotrexate on radiographic progression in rheumatoid arthritis: comment on the article by Emery et al

    Graudal, N. & Jürgens, G., 2012, In: Arthritis & Rheumatism. 64, 4, p. 1297-8; author reply 1298-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Effects of low-sodium diet vs. high-sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride (Cochrane Review)

    Graudal, N. A., Hubeck-Graudal, T. & Jürgens, G., 2012, In: American Journal of Hypertension. 25, 1, p. 1-15 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Utility and adoption of CYP2D6 and CYP2C19 genotyping and its translation into psychiatric clinical practice

    Jürgens, G., Jacobsen, C. B., Rasmussen, H. B., Werge, T. M., Nordentoft, M. & Andersen, S. E., 2012, In: Acta Psychiatrica Scandinavica. 125, 3, p. 228-37 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. 2011
  54. Published

    Genome-wide association study identifies five new schizophrenia loci

    Ripke, S., Sanders, A. R., Kendler, K. S., Levinson, D. F., Sklar, P., Holmans, P. A., Lin, D-Y., Duan, J., Ophoff, R. A., Andreassen, O. A., Scolnick, E., Cichon, S., St Clair, D., Corvin, A., Gurling, H., Werge, T., Rujescu, D., Blackwood, D. H. R., Pato, C. N., Malhotra, A. K., Purcell, S., Dudbridge, F., Neale, B. M., Rossin, L., Visscher, P. M., Posthuma, D., Ruderfer, D. M., Fanous, A., Stefansson, H., Steinberg, S., Mowry, B. J., Golimbet, V., De Hert, M., Jönsson, E. G., Bitter, I., Pietiläinen, O. P. H., Collier, D. A., Fink-Jensen, A., Glenthøj, B., Ingason, A., Jakobsen, K. D., Jürgens, G., Nordentoft, M., Olsen, L., Rasmussen, H. B., Thygesen, J. H., Timm, S., Wang, A. G., The Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium, Werge, T. M. & Hansen, T. F., 18 Sep 2011, In: Nature Genetics. 43, p. 969-976

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Common Variants at VRK2 and TCF4 Conferring Risk of Schizophrenia

    Steinberg, S., de Jong, S., Andreassen, O. A., Werge, T., Børglum, A., Mors, O., Mortensen, P. B., Gustafsson, O., Costas, J., Pietiläinen, O. P. H., Demontis, D., Papiol, S., Huttenlocher, J., Mattheisen, M., Breuer, R., Vassos, E., Giegling, I., Fraser, G., Walker, N., Tuulio-Henriksson, A., Suvisaari, J., Lönnqvist, J., Paunio, T., Agartz, I., Melle, I., Djurovic, S., Strengman, E., Jürgens, G., Glenthøj, B., Terenius, L., Hougaard, D. M., Orntoft, T., Wiuf, C. H., Didriksen, M., Hollegaard, M. V., Nordentoft, M., van Winkel, R., Kenis, G., Abramova, L., Kaleda, V., Arrojo, M., Sanjuán, J., Arango, C., Sperling, S., Rossner, M., Ribolsi, M., Magni, V., Siracusano, A., Christiansen, C., Kiemeney, L. A. & Irish Schizophrenia Genomics Consortium, 26 Jul 2011, In: Human Molecular Genetics. 20, 20, p. 4076-4081

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Non-typhoidal Salmonella and Campylobacter infections among HIV-positive patients in Denmark

    Jürgens, G., Larsen, I. K., Gradel, K. O., Helms, M., Hornstrup, M. K., Mens, H., Rosager, C. L., Clausen, T. H., Kronborg, G. & Nielsen, H., 1 Jan 2011, In: Scandinavian Journal of Infectious Diseases. 43, 1, p. 3-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Expanding the range of ZNF804A variants conferring risk of psychosis

    Steinberg, S., Mors, O., Børglum, A., Gustafsson, O., Werge, T., Mortensen, P. B., Andreassen, O. A., Sigurdsson, E., Thorgeirsson, T. E., Böttcher, Y., Olason, P., Ophoff, R. A., Cichon, S., Gudjonsdottir, I. H., Pietiläinen, O. P. H., Nyegaard, M., Tuulio-Henriksson, A., Ingason, A., Hansen, T. F., Athanasiu, L., Suvisaari, J., Lonnqvist, J., Paunio, T., Hartmann, A., Jürgens, G., Nordentoft, M., Hougaard, D., Norgaard-Pedersen, B., Breuer, R., Möller, H-J., Giegling, I., Glenthøj, B., Rasmussen, H. B., Mattheisen, M., Bitter, I., Réthelyi, J. M., Sigmundsson, T., Fossdal, R., Thorsteinsdottir, U., Ruggeri, M., Tosato, S., Strengman, E., Kiemeney, L. A., Melle, I., Djurovic, S., Abramova, L., Kaleda, V., Walshe, M., Bramon, E., Vassos, E. & Genetic Risk and Outcome in Psychosis, Jan 2011, In: Molecular Psychiatry. 16, 1, p. 59-66 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride

    Graudal, N. A., Hubeck-Graudal, T. & Jurgens, G., 2011, In: Cochrane Database of Systematic Reviews. 11, p. CD004022

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    The sodium phantom

    Graudal, N. & Jürgens, G., 2011, In: B M J. 343, p. d6119; author reply d6121

    Research output: Contribution to journalJournal articleCommunication

  60. 2010
  61. Published

    Biologisk førstevalgspraeparat i Region H

    Graudal, N., Jacobsen, S., Baslund, B. & Jürgens, G., 8 Nov 2010, In: Ugeskrift for Laeger. 172, 45, p. 3127

    Research output: Contribution to journalJournal articleResearchpeer-review

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