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1993 …2023

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Personal profile


I am appointed as professor i Gastroenterology and Hepatology with special focus on liver failure. The focus is primarily on patients with acute liver failure and patients with cirrhosis that suddenly decompensate ("acute-on-chronic-liver failure").

Besides these two main areas of focus we also do RCT in patients with autoimmune liver disease, in patients with alcoholic hepatitis, as well as in chronic viral hepatitis.

Main research areas

Focus is mainly two folded: We study the pathophysiology and try to improvemanagement of the many extrahepatic complications that often develop, such as hepatic encephalopathy, brain edema and cardiovascular dysfunction. The second main focus area is concerned with liver assist devices (high-volume plasmapheresis (HVP), MARS, TetraMARS ect).

The clinic also focuses on alcohol-related liver disease. This applies to both alcoholic hepatitis and alcoholic cirrhosis and is based both on epidemiological and genetic studies.
Articles are published in national and international journals.

Current research

HVP improve the survival in patients with acute liver failure. We are now about to launch as similar study in patients with acute-on-chronic-liver failure in cooperation with 6 ICU centers in the US and 16 centers here in Europe. The primary end point will be survival in a RCT design

Potential conflicts of interest



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