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The Capital Region of Denmark - a part of Copenhagen University Hospital
Filip Krag Knop

Filip Krag Knop

Chief Consultant

Niels Steensens Vej 2-4

2820 Gentofte

Denmark

​Gentofte Hospital

Building: Opgang ​7, 3. sal, Kildegårdsvej 28

2900 Hellerup

Denmark

  1. 2018
  2. Published

    Glucose-dependent insulinotropic polypeptide (GIP) receptor antagonists as anti-diabetic agents

    Gasbjerg, L. S., Gabe, M. B. N., Hartmann, B., Christensen, M. B., Knop, F. K., Holst, J. J. & Rosenkilde, M. M., Feb 2018, In : Peptides. 100, p. 173-181 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published
  4. Published
  5. Published
  6. Published
  7. Published

    Glucose-Dependent Insulinotropic Polypeptide (GIP) Inhibits Bone Resorption independently of Insulin and Glycemia

    Christensen, M. B., Lund, A., Calanna, S., Jørgensen, N. R., Holst, J. J., Vilsbøll, T. & Knop, F. K., 2018, In : The Journal of clinical endocrinology and metabolism. 103, 1, p. 288-294 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Kender vi til DPP-4 hæmmernes egentlig virkningsmekanisme?

    Andersen, E. S., Vilsbøll, T. & Knop, F. K., 2018, Best Practice

    Research output: Other contributionResearch

  9. 2017
  10. Published

    Dilemma med danske julefrokoster

    Lanng, A. R., Gasbjerg, L. S. & Knop, F. K., 11 Dec 2017, In : Ugeskrift for Laeger. 179, 50

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Impaired beta cell sensitivity to incretins in type 2 diabetes is insufficiently compensated by higher incretin response

    Tura, A., Bagger, J. I., Ferrannini, E., Holst, J. J., Knop, F. K., Vilsbøll, T. & Mari, A., Dec 2017, In : Nutrition, metabolism, and cardiovascular diseases : NMCD. 27, 12, p. 1123-1129 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

    Wewer Albrechtsen, N. J., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jørgensen, N. B., Gabe, M. N., Balk-Møller, E., Albrechtsen, R., Winther-Sørensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsbøll, T., Eliasen, R., Bojsen-Møller, K. N., Idorn, T., Deacon, C. F., Knop, F. K., Rosenkilde, M. M., Hartmann, B., Feldt-Rasmussen, B., Mann, M., Madsbad, S. & Holst, J. J., 1 Nov 2017, In : Cell Reports. 21, 6, p. 1452-1460

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Single-dose Metformin Enhances Bile Acid-Induced GLP-1 Secretion in Patients with Type 2 Diabetes

    Brønden, A., Albér, A., Rohde, U., Rehfeld, J. F., Holst, J. J., Vilsbøll, T. & Knop, F. K., 1 Nov 2017, In : The Journal of clinical endocrinology and metabolism. 102, 11, p. 4153-4162 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published
  15. Published

    Current Therapies That Modify Glucagon Secretion: What Is the Therapeutic Effect of Such Modifications?

    Grøndahl, M. F., Keating, D. J., Vilsbøll, T. & Knop, F. K., 28 Oct 2017, In : Current Diabetes Reports. 17, 12, p. 128

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition

    Kootte, R. S., Levin, E., Salojärvi, J., Smits, L. P., Hartstra, A. V., Udayappan, S. D., Hermes, G., Bouter, K. E., Koopen, A. M., Holst, J. J., Knop, F. K., Blaak, E. E., Zhao, J., Smidt, H., Harms, A. C., Hankemeijer, T., Bergman, J. J. G. H. M., Romijn, H. A., Schaap, F. G., Olde Damink, S. W. M., Ackermans, M. T., Dallinga-Thie, G. M., Zoetendal, E., de Vos, W. M., Serlie, M. J., Stroes, E. S. G., Groen, A. K. & Nieuwdorp, M., 3 Oct 2017, In : Cell Metabolism. 26, 4, p. 611-619.e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Mathematical Modelling of Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide-1 following Ingestion of Glucose

    Røge, R. M., Bagger, J. I., Alskär, O., Kristensen, N. R., Klim, S., Holst, J. J., Ingwersen, S. H., Karlsson, M. O., Knop, F. K., Vilsbøll, T. & Kjellsson, M. C., Oct 2017, In : Basic & clinical pharmacology & toxicology. 121, 4, p. 290-297 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Metformin potentiates bile acid-induced GLP-1 secretion in patients with type 2 diabetes

    Brønden, A., Albér, A., Rohde, U., Rehfeld, J. F., Holst, J. J., Vilsbøll, T. & Knop, F. K., 15 Sep 2017.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  19. Published

    Bone turnover in women with prior gestational diabetes after 52 week's treatment with liraglutide

    Vedtofte, L., Nielsen-Hannerup, E., Foghsgaard, S., Mathiesen, E. R., Buhl, T., Christiansen, L. K., Svare, J., Clausen, T. D., Damm, P., Jørgensen, N. R., Knop, F. K. & Vilsbøll, T., 14 Sep 2017. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  20. Published

    GIP(3-30)NH2 is an efficacious GIP receptor antagonist in humans

    Gasbjerg, L. S., Lanng, A. R., Hartmann, B., Sparre-Ulrich, A. H., Dela, F., Christensen, M., Holst, J. J., Vilsbøll, T., Rosenkilde, M. & Knop, F. K., 14 Sep 2017. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  21. Published

    Increased liver fat content in totally pancreatectomised patients

    Bagger, J. I., Lund, A., Albrechtsen, N. J. W., Christensen, M., Grøndahl, M., Hansen, C. P., Storkholm, J. H., Holst, J. J., Vilsbøll, T. & Knop, F. K., 14 Sep 2017.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  22. Published

    The role of glucagon in gastrointestinal-mediated glucose-disposal and incretin effect in patients with type 2 diabetes and normal glucose tolerant individuals

    Nielsen-Hannerup, E., Hædersdal, S., Lund, A., Maagensen, HEG., Holst, J. J., Knop, F. K. & Vilsbøll, T., 14 Sep 2017. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  23. Published

    Autonomic regulation may modify the weight reducing effect of liraglutide in overweight patients with type 1 diabetes

    Hansen, C. S., Frandsen, C. S., Fleischer, J., Vistisen, D., Tarnov, L., Knop, F. K., Madsbad, S., Andersen, H. U. & Dejgaard, T. F., 13 Sep 2017. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  24. Published

    Role of the gut in glucose-induced suppression of bone resorption in patients with non-alcoholic fatty liver disease and/or type 2 diabetes

    Maagensen, HEG., Junker, A. E., Jørgensen, N. R., Gluud, L. L., Knop, F. K. & Vilsbøll, T., 13 Sep 2017. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  25. Published

    The effect of liraglutide on bone turnover during exercise training in patients with type 2 diabetes

    Mensberg, P., Espersen, E., Sjøberg, K. A., Storgaard, H., Jørgensen, N. R., Nyby, S., Kiens, B., Richter, E., Knop, F. K. & Vilsbøll, T., 13 Sep 2017. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  26. Published

    The effect of liraglutide on oxidative nucleic acid modifications in women with prior gestational diabetes

    Larsen, E. L., Foghsgaard, S., Vedtofte, L., Mathiesen, E. R., Damm, P., Svare, J., Clausen, T. D., Henriksen, T., Poulsen, H. E., Knop, F. K. & Vilsbøll, T., 13 Sep 2017. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  27. Published

    The glucagon-like peptide-1 receptor agonist lixisenatide reduces postprandial glucose excursions in totally pancreatectomised patients

    Juel, C. T-B., Lund, A., Hansen, C. P., Storkholm, J. H., Wewer Albrechtsen, N. J., Holst, J. J., Vilsbøll, T. & Knop, F. K., 13 Sep 2017. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  28. Published

    Is double-blinding achievable in a placebo-controlled trial with the glucagon-like-peptide-1 receptor agonist liraglutide?

    Foghsgaard, S., Vedtofte, L., Bahne, E., Andreasen, C., Christiansen, L. K., Svare, J., Clausen, T. D., Mathiesen, E. R., Damm, P., Gluud, L. L., Knop, F. K. & Vilsbøll, T., 12 Sep 2017. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  29. Published

    The effects of GIP/GLP-1 receptor co-activation on appetite and food intake in overweight/obese subjects

    Bergmann, N., Lund, A., Gasbjerg, L. S., Meessen, E. C. E., Christensen, M., Vilsbøll, T. & Knop, F. K., 12 Sep 2017. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  30. Published

    Weight loss for overweight and obese individuals with gout: a systematic review of longitudinal studies

    Nielsen, S. M., Bartels, E. M., Henriksen, M., Wæhrens, E. E., Gudbergsen, H., Bliddal, H., Astrup, A., Knop, F. K., Carmona, L., Taylor, W. J., Singh, J. A., Perez-Ruiz, F., Kristensen, L. E. & Christensen, R., 2 Sep 2017, In : Annals of the Rheumatic Diseases. 76, 11

    Research output: Contribution to journalReviewResearchpeer-review

  31. Published

    Beta cell secretory responses to oral ethanol and isoethanolaemic i.v. ethanol in healthy subjects

    Lanng, A. R., Gasbjerg, L. S., Bergmann, N., Holst, J. J., Vilsbøll, T. & Knop, F. K., 1 Sep 2017.

    Research output: Contribution to conferencePosterResearchpeer-review

  32. Published

    A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite

    Wewer Albrechtsen, N. J., Asmar, A., Jensen, F., Törang, S., Simonsen, L., Kuhre, R. E., Asmar, M., Veedfald, S., Plamboeck, A., Knop, F. K., Vilsboll, T., Madsbad, S., Nauck, M. A., Deacon, C. F., Bulow, J., Holst, J. J. & Hartmann, B., Sep 2017, In : A J P: Endocrinology and Metabolism (Online). p. e284-e291 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Evidence connecting old, new and neglected glucose-lowering drugs to bile acid-induced GLP-1 secretion: A review

    Kårhus, M. L., Brønden, A., Sonne, D. P., Vilsbøll, T. & Knop, F. K., Sep 2017, In : Diabetes, Obesity and Metabolism. p. 1214-1222 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  34. Published

    [Gastric aspiration therapy is a possible alternative to treatment of obesity

    Christensen, M. M., Jorsal, T., Naver, L. P. S., Vilsbøll, T. & Knop, F. K., 7 Aug 2017, In : Ugeskrift for Laeger. 179, 32

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Gastrisk aspirationsbehandling er et muligt alternativ til behandling af fedme

    Christensen, M. M., Jorsal, T., Naver, L. P. S., Vilsbøll, T. & Knop, F. K., 7 Aug 2017, In : Ugerskrift for Læger.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The Gut: A Key to the Pathogenesis of Type 2 Diabetes?

    Wewer Albrechtsen, N. J., Knop, F. K. & HOlst, J. J., Aug 2017, In : Metabolic Syndrome and Related Disorders. 15, 6, p. 259-262 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published
  38. Published

    Clinical Pharmacokinetics and Pharmacodynamics of Albiglutide

    Brønden, A., Knop, F. K. & Christensen, M. B., Jul 2017, In : Clinical Pharmacokinetics. 56, 7, p. 719-731 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  39. Published
  40. Published
  41. Published

    Short-acting glucagon-like peptide-1 receptor agonists as add-on to insulin therapy in type 1 diabetes: A review

    Albèr, A., Brønden, A. & Knop, F. K., Jul 2017, In : Diabetes, Obesity and Metabolism. 19, 7, p. 915-925 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  42. Published

    Glucagon-Like Peptide-1 Agonists and Risk of Acute Pancreatitis in Patients with Type 2 Diabetes

    Storgaard, H., Cold, F., Gluud, L. L., Vilsbøll, T. & Knop, F. K., 1 Jun 2017, In : Diabetes, Obesity and Metabolism. 19, 6, p. 906-908

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    The effect of empagliflozin on oxidative nucleic acid modifications in patients with type 2 diabetes: protocol for a randomised, double-blinded, placebo-controlled trial

    Larsen, E. L., Cejvanovic, V., Kjær, L. K., Vilsbøll, T., Knop, F. K., Rungby, J. & Poulsen, H. E., 9 May 2017, In : B M J Open. 7, 5, p. e014728

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Therapy: Liraglutide - preventing or postponing T2DM diagnosis?

    Vilsbøll, T. & Knop, F. K., 5 May 2017, In : Nature reviews. Endocrinology. 13, 6, p. 320-322 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published
  46. Published
  47. Published

    Postprandial Plasma Concentrations of ProANP in Patients with Type 2 Diabetes and Healthy Controls

    Sonne, D. P., Terzic, D., Knop, F. K. & Goetze, J. P., May 2017, In : Clinical Chemistry. 63, 5, p. 1040-1041 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Exenatide: pharmacokinetics, clinical use, and future directions

    Knop, F. K., Brønden, A. & Vilsbøll, T., Apr 2017, In : Expert Opinion on Pharmacotherapy. 18, 6, p. 555-571 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  49. Published

    Adult atopic dermatitis and the risk of type 2 diabetes

    Andersen, Y. M. F., Egeberg, A., Gislason, G. H., Skov, L., Knop, F. K. & Thyssen, J. P., Mar 2017, In : The Journal of allergy and clinical immunology. 139, 3, p. 1057-1059

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Cardiovascular safety and benefits of GLP-1 receptor agonists

    Dalsgaard, N. B., Brønden, A., Vilsbøll, T. & Knop, F. K., Mar 2017, In : Expert Opinion on Drug Safety. 16, 3, p. 351-363 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Clinical relevance of the bile acid receptor TGR5 in metabolism

    van Nierop, F. S., Scheltema, M. J., Eggink, H. M., Pols, T. W., Sonne, D. P., Knop, F. K. & Soeters, M. R., Mar 2017, In : The Lancet Diabetes and Endocrinology. 5, 3, p. 224-233

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

ID: 31007257