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The Capital Region of Denmark - a part of Copenhagen University Hospital
Filip Krag Knop

Filip Krag Knop

Chief Consultant

Niels Steensens Vej 2-4

2820 Gentofte

Denmark

​Gentofte Hospital

Building: Opgang ​7, 3. sal, Kildegårdsvej 28

2900 Hellerup

Denmark

  1. 2019
  2. Published

    Biomarkører for kardiovaskulær sygdom ved type 2-diabetes

    Krogh, S. K., Andersen, A., Knop, F. K. & Vilsbøll, T., 18 Feb 2019, In : Ugeskrift for Laeger. 181, V10180711 .

    Research output: Contribution to journalJournal articleCommunication

  3. Published

    Glucagon-like peptide-1 receptor-agonists for antipsychotic-associated cardio-metabolic risk factors: a systematic review and individual participant data meta-analysis

    Siskind, D., Hahn, M., Correll, C. U., Fink-Jensen, A., Russell, A. W., Bak, N., Broberg, B. V., Larsen, J., Ishøy, P. L., Vilsbøll, T., Knop, F. K., Kisely, S. & Ebdrup, B. H., 1 Feb 2019, In : Diabetes, Obesity and Metabolism. 21, 2, p. 293-302 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Glucose metabolism in patients with psoriasis

    Friis, N. U., Hoffmann, N., Gyldenløve, M., Skov, L., Vilsbøll, T., Knop, F. K. & Storgaard, H., 1 Feb 2019, In : British Journal of Dermatology. 180, 2, p. 264-271 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Glucose metabolism in patients with psoriasis

    Friis, N. U., Hoffmann, N., Gyldenløve, M., Skov, L., Vilsbøll, T., Knop, F. K. & Storgaard, H., Feb 2019, In : British Journal of Dermatology. 180, 2, p. 264-271 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published
  7. Published

    Extrapancreatic glucagon: present status

    Lund, A. & Knop, F. K., 1 Jan 2019, In : Diabetes Research and Clinical Practice. 147, p. 19-28 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published
  9. 2018
  10. Published

    Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes

    Bahne, E., Sun, E. W. L., Young, R. L., Hansen, M., Sonne, D. P., Hansen, J. S., Rohde, U., Liou, A. P., Jackson, M. L., de Fontgalland, D., Rabbitt, P., Hollington, P., Sposato, L., Due, S., Wattchow, D. A., Rehfeld, J. F., Holst, J. J., Keating, D. J., Vilsbøll, T. & Knop, F. K., 6 Dec 2018, In : JCI Insight. 3, 23, p. 93936

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Response to: Letter to the Editor: Hemodynamic Effects of Glucagon - A literature Review

    Meidahl Petersen, K., Bøgevig, S., Holst, J. J., Knop, F. K. & Christensen, M. B., 1 Dec 2018, In : The Journal of clinical endocrinology and metabolism. 103, 12, p. 4480–4481 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  12. Published
  13. Published
  14. Published

    Changes in urinary excretion of oxidative nucleic acid modifications in the week following Copenhagen Marathon 2018, Denmark

    Larsen, E. L., Kjaer, L. K., Michaelsen, C., Andersen, E., Lyngbaek, M., Petersen-Bonding, C., Henriksen, T., Vilsboll, T., Knop, F. K., Ploug, T., Poulsen, H. E. & Karstoft, K., 20 Nov 2018, In : Free Radical Biology and Medicine. 128, 1, p. S54

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  15. Published

    Future Perspectives on GLP-1 Receptor Agonists and GLP-1/glucagon Receptor Co-agonists in the Treatment of NAFLD

    Seghieri, M., Christensen, A. S., Andersen, A., Solini, A., Knop, F. K. & Vilsbøll, T., 6 Nov 2018, In : Frontiers in Endocrinology. 9, p. 649

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Effects of liraglutide on gallbladder emptying: a randomised, placebo-controlled trial in adults with overweight or obesity

    Nexøe-Larsen, C. C., Sørensen, P. H., Hausner, H., Agersnap, M., Baekdal, M., Brønden, A., Gustafsson, L. N., Sonne, D. P., Vedtofte, L., Vilsbøll, T. & Knop, F. K., Nov 2018, In : Diabetes, Obesity and Metabolism Online. 20, 11, p. 2557-2564 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Recovery of gut microbiota of healthy adults following antibiotic exposure

    Palleja, A., Mikkelsen, K. H., Forslund, S. K., Kashani, A., Allin, K. H., Nielsen, T., Hansen, T. H., Liang, S., Feng, Q., Zhang, C., Pyl, P. T., Coelho, L. P., Yang, H., Wang, J., Typas, A., Nielsen, M. F., Nielsen, H. B., Bork, P., Wang, J., Vilsbøll, T., Hansen, T., Knop, F. K., Arumugam, M. & Pedersen, O., Nov 2018, In : Nature Microbiology. 3, 11, p. 1255-1265 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published
  19. Published

    Diverse hepatic microbial DNA fingerprints in healthy lean and obese steatotic humans

    Bagger, J. I., Suppli, M. P., Nielsen, T., Lelouvier, B., Broha, A., Demant, M. G., Kønig, M. J., Strandberg, C., Lund, A., Vilsbøll, T. & Knop, F. K., 2 Oct 2018, In : Diabetologia. 61, supll 1, p. S120-S121 1 p., 236.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  20. Published

    High intensity interval training improves insulin sensitivity in individuals with prediabetes

    Mensberg, P., Frandsen, C., Espersen, E., Leineweber, T., Storgaard, H., Schlawitz, K., Petersen, T., Poulsen, J., Sørensen, F., Forman, J., Knop, F. K. & Vilsbøll, T., 1 Oct 2018, In : Diabetologia. 61, Suppl 1, p. S217-S218 1 p., 441.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  21. Published

    Individual and combined glucose-lowering effects of glucagon receptor antagonism and dipeptidyl peptidase-4 inhibition

    Maagensen, H., Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Holst, J. J., Knop, F. K. & Vilsbøll, T., 1 Oct 2018, In : Diabetologia. 61, suppl 1, p. S246-S247 1 p., 504.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  22. Published

    Individual and combined glucose-lowering effects of glucagon receptor antagonism and sodium-glucose cotransporter 2 inhibition

    Hædersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Holst, J. J., Knop, F. K. & Vilsbøll, T., 1 Oct 2018, In : Diabetologia. 61, Suppl 1, p. S312-S312 1 p., 642.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  23. Published

    Metabolomics reveal changes in plasma concentrations of 3-hydroxybutyric acid, citric acid, oleic acid and proline in gestational diabetes

    Johansen, N. J., Demant, M. G., Suvitaival, T., Trošt, K., Ahonen, L. L., Bonde, L., Svare, J., Quigley, C., Vilsbøll, T. & Knop, F. K., 1 Oct 2018, In : Diabetologia. 61, Suppl 1, p. S252-S252 1 p., 514.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  24. Published

    Mono- and co-activation of the GIP and GLP-1 receptors inhibits bone resorption

    Bergmann, N., Lund, A., Heimbürger, S. M., Gasbjerg, L. S., Jørgensen, N. R., Jessen, L., Hartmann, B., Holst, J. J., Christensen, M., Vilsbøll, T. & Knop, F. K., 1 Oct 2018, In : Diabetologia. 61, suppl 1, p. S348-S348 1 p., 717.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  25. Published

    More subjects achieved composite reductions of ≥1% HbA1c, ≥5% body weight and ≥5 mmHg SBP with semaglutide vs comparators across the SUSTAIN 1-5 and 7 trials

    Dungan, K., Aroda, V. R., Knop, F. K., Leiter, L. A., Lausvig, N., Lindberg, S., Ferløv Schwensen, J. & Meier, J., 1 Oct 2018, In : Diabetologia. 61, suppl1, p. S359-S360 1 p., 738.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  26. Published

    Novel Biomarker Discovery in Non-Alcoholic Steatohepatitis (NASH): Translation of Complex Data into Clear Results

    Veidal, S., Rigbolt, K., Petersen, P. S., Suppli, M., Bagger, J. I., Lund, A., Heeboll, S., Gronbaek, H., Vilsboll, T., Knop, F. K., Vrang, N. & Jelsing, J., 1 Oct 2018, In : Hepatology. 68, 1, p. 1013A

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  27. Published

    Postprandial effects of individual and combined GIP and GLP-1 receptor antagonism in healthy subjects

    Gasbjerg, L. S., Helsted, M. M., Sparre-Ulrich, A. H., Lanng, A. R., Stensen, S., Jakobsen, M. H., Hartmann, B., Christensen, M., Holst, J. J., Vilsbøll, T., Rosenkilde, M. M. & Knop, F. K., 1 Oct 2018, In : Diabetologia. 61, suppl 1, p. S246-S246 1 p., 503.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  28. Published

    The effect of Roux-en-Y gastric bypass surgery on the gut mucosal gene expression profile and circulating gut hormones

    Christensen, M. M., Jorsal, T., Mortensen, B., Wandall, E. P., Langholz, E., Friis, S. U., Worm, D., Støving, R. K., Aldries, A., Juhl, C. B., Rehfeld, J. F., Vrang, N., Jelsing, J., Vilsbøll, T. & Knop, F. K., 1 Oct 2018, In : Diabetologia. 61, Suppl 1, p. S248-S249 1 p., 508.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  29. Published

    The role of the incretins in the postprandial bone remodelling

    Helsted, M. M., Gasbjerg, L. S., Lanng, A. R., Stensen, S., Hartmann, B., Christensen, M., Holst, J. J., Vilsbøll, T., Rosenkilde, M. & Knop, F. K., 1 Oct 2018, In : Diabetologia. 61, Suppl 1, p. S221-S221 1 p., 449.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  30. Published

    Preclinical discovery and development of colesevelam for the treatment of type 2 diabetes

    Nerild, H. H., Christensen, M. B., Knop, F. K. & Brønden, A., Oct 2018, In : Expert Opinion on Drug Discovery. 13, 12, p. 1161-1167 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    No changes in levels of bone formation and resorption markers following a broad-spectrum antibiotic course

    Mikkelsen, K. H., Vilsbøll, T., Holst, J. J., Hartmann, B., Knop, F. K. & Frost, M., 4 Sep 2018, In : BMC Endocrine Disorders. 18, 1, p. 60

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Differences Between Randomized Clinical Trial Patients and Real-World Initiators of the Glucagon-Like Peptide 1 Receptor Agonist Liraglutide

    Knudsen, J. S., Thomsen, R. W., Pottegård, A., Knop, F. K. & Sørensen, H. T., Sep 2018, In : Diabetes Care. 41, 9, p. e133-e135 2 p.

    Research output: Contribution to journalLetterResearchpeer-review

  33. Published

    Model-Based Prediction of Plasma Concentration and Enterohepatic Circulation of Total Bile Acids in Humans

    Guiastrennec, B., Sonne, D. P., Bergstrand, M., Vilsbøll, T., Knop, F. K. & Karlsson, M. O., Sep 2018, In : CPT: pharmacometrics & systems pharmacology. 7, 9, p. 603-612 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Is glucagon-like peptide-1 fully protected by dipeptidyl peptidase 4 inhibitor administration in patients with type 2 diabetes?

    Andersen, E. S., Lund, A., Bagger, J. I., Andreasen, C., Grøndahl, M. F., Deacon, C. F., Hartmann, B., Holst, J. J., Knop, F. K. & Vilsbøll, T., Aug 2018, In : Diabetes, Obesity and Metabolism. 20, 8, p. 1937-1943 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    The Effect of Ethanol on Inflammation Markers and FGF-21 in Healthy Individuals

    Lanng, A. R., Gasbjerg, L. S., Bergmann, N., Møller, H. J., Gillum, M. P., Grønbæk, H., Vilsbøll, T. & Knop, F. K., 1 Jul 2018, In : Diabetes. 67, Suppl 1

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  36. Published

    Glucose-lowering effects and mechanisms of the bile acid-sequestering resin sevelamer

    Brønden, A., Mikkelsen, K., Sonne, D. P., Hansen, M., Våben, C., Gabe, M. N., Rosenkilde, M., Tremaroli, V., Wu, H., Bäckhed, F., Rehfeld, J. F., Holst, J. J., Vilsbøll, T. & Knop, F. K., Jul 2018, In : Diabetes, Obesity and Metabolism. 20, 7, p. 1623-1631 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published
  38. Published

    Cardiovascular biomarkers in clinical studies of type 2 diabetes

    Baldassarre, M. P. A., Andersen, A., Consoli, A., Knop, F. K. & Vilsbøll, T., Jun 2018, In : Diabetes, Obesity and Metabolism. 20, 6, p. 1350–1360 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  39. Published

    Effects of Smoking Versus Nonsmoking on Postprandial Glucose Metabolism in Heavy Smokers Compared With Nonsmokers

    Grøndahl, M. F., Bagger, J. I., Lund, A., Faurschou, A., Rehfeld, J. F., Holst, J. J., Vilsbøll, T. & Knop, F. K., Jun 2018, In : Diabetes Care. 41, 6, p. 1260-1267 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    EJE PRIZE 2018: A gut feeling about glucagon

    Knop, F. K., Jun 2018, In : European Journal of Endocrinology. 178, 6, p. R267-R280

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    Ghrelin secretion in humans - a role for the vagus nerve?

    Veedfald, S., Plamboeck, A., Hartmann, B., Vilsbøll, T., Knop, F. K., Deacon, C. F., Svendsen, L. B. & Holst, J. J., Jun 2018, In : Neurogastroenterology and Motility. 30, 6, p. e13295

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published
  43. Published

    FGF21, a liver hormone that inhibits alcohol intake in mice, increases in human circulation after acute alcohol ingestion and sustained binge drinking at Oktoberfest

    Søberg, S., Andersen, E. S., Dalgaard, N. B., Jarlhelt, I., Hansen, N. L., Hoffmann, N., Vilsbøll, T., Chenchar, A., Jensen, M., Grevengoed, T. J., Trammell, S. A. J., Knop, F. K. & Gillum, M. P., 1 May 2018, In : Molecular Metabolism. 11, p. 96-103 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Hemodynamic Effects of Glucagon - A Literature Review

    Meidahl Petersen, K., Bøgevig, S., Holst, J. J., Knop, F. K. & Christensen, M. B., 1 May 2018, In : The Journal of clinical endocrinology and metabolism. 103, 5, p. 1804-1812 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published
  46. Published
  47. Published

    Glucagon-like peptide 1 in health and disease

    Andersen, A., Lund, A., Knop, F. K. & Vilsbøll, T., May 2018, In : Nature reviews. Endocrinology. 14, p. 390-403 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Restoration of enteroendocrine and pancreatic function after internal hernia and short bowel syndrome in a young woman with gastric bypass - a 2-year follow-up

    Borghede, M., Vinter-Jensen, L., Rasmussen, H. H., Veedfald, S., Rehfeld, J. F., Hartmann, B., Holst, J. J., Knop, F. K. & Sonne, D. P., May 2018, In : Physiological Reports. 6, 9, p. e13686

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Metformin er en mulig glukagonlignende peptid-1-stimulator

    Bahne, E., Brønden, A., Vilsbøll, T. & Knop, F. K., 19 Mar 2018, In : Ugeskrift for Laeger. 180, 12, p. 2-5 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Effects of glucagon-like peptide-1 (GLP-1) receptor agonists on cardiovascular risk factors: a narrative review of head-to-head comparisons

    Dalsgaard, N. B., Vilsbøll, T. & Knop, F. K., Mar 2018, In : Diabetes, Obesity and Metabolism. 20, 3, p. 205-2019 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Evidence of a liver-alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids

    Wewer Albrechtsen, N. J., Færch, K., Jensen, T. M., Witte, D. R., Pedersen, J., Mahendran, Y., Jonsson, A. E., Galsgaard, K. D., Winther-Sørensen, M., Torekov, S. S., Lauritzen, T., Pedersen, O., Knop, F. K., Hansen, T., Jørgensen, M. E., Vistisen, D. & Holst, J. J., Mar 2018, In : Diabetologia. 61, 3, p. 671-680 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Guanylin and uroguanylin mRNA expression is increased following Roux-en-Y gastric bypass, but guanylins do not play a significant role in body weight regulation and glycemic control

    Fernandez-Cachon, M. L., Pedersen, S. L., Rigbolt, K. T., Zhang, C., Fabricius, K., Hansen, H. H., Elster, L., Fink, L. N., Schäfer, M., Rhee, N. A., Langholz, E., Wandall, E., Friis, S. U., Vilmann, P., Kristiansen, V. B., Schmidt, C., Schreiter, K., Breitschopf, K., Hübschle, T., Jorsal, T., Vilsbøll, T., Schmidt, T., Theis, S., Knop, F. K., Larsen, P. J. & Jelsing, J., Mar 2018, In : Peptides. 101, p. 32-43

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 31007257