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The Capital Region of Denmark - a part of Copenhagen University Hospital
Filip Krag Knop

Filip Krag Knop

Chief Consultant

Niels Steensens Vej 2-4

2820 Gentofte

Denmark

​Gentofte Hospital

Building: Opgang ​7, 3. sal, Kildegårdsvej 28

2900 Hellerup

Denmark

  1. 2019
  2. Published

    Investigating Intestinal Glucagon after Roux-en-Y Gastric Bypass Surgery

    Jorsal, T., Wewer Albrechtsen, N. J., Christensen, M. M., Mortensen, B., Wandall, E., Langholz, E., Friis, S., Worm, D., Ørskov, C., Støving, R. K., Andries, A., Juhl, C. B., Sørensen, F., Forman, J. L., Falkenhahn, M., Musholt, P. B., Theis, S., Larsen, P. J., Holst, J. J., Vrang, N., Jelsing, J., Vilsbøll, T. & Knop, F. K., 1 Dec 2019, In : The Journal of clinical endocrinology and metabolism. 104, 12, p. 6403-6416 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. E-pub ahead of print
  4. E-pub ahead of print

    GIP and the gut-bone axis - physiological, pathophysiological and potential therapeutic implications

    Stensen, S., Gasbjerg, L. S., Helsted, M. M., Hartmann, B., Christensen, M. B. & Knop, F. K., 9 Nov 2019, In : Peptides. p. 170197

    Research output: Contribution to journalReviewResearchpeer-review

  5. E-pub ahead of print

    Evaluation of the incretin effect in humans using GIP and GLP-1 receptor antagonists

    Gasbjerg, L. S., Bergmann, N. C., Stensen, S., Christensen, M. B., Rosenkilde, M. M., Holst, J. J., Nauck, M. & Knop, F. K., 3 Nov 2019, In : Peptides.

    Research output: Contribution to journalReviewResearchpeer-review

  6. E-pub ahead of print

    Glucose-dependent insulinotropic polypeptide (GIP) and cardiovascular disease

    Heimbürger, S. M., Bergmann, N. C., Augustin, R., Gasbjerg, L. S., Christensen, M. B. & Knop, F. K., 2 Nov 2019, In : Peptides.

    Research output: Contribution to journalReviewResearchpeer-review

  7. E-pub ahead of print

    GIP's involvement in the pathophysiology of type 2 diabetes

    Christensen, M. B., Gasbjerg, L. S., Heimbürger, S. M., Stensen, S., Vilsbøll, T. & Knop, F. K., 1 Nov 2019, In : Peptides.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Non-alcoholic fatty liver disease alters expression of genes governing hepatic nitrogen conversion

    Eriksen, P. L., Vilstrup, H., Rigbolt, K., Suppli, M. P., Sørensen, M., Heebøll, S., Veidal, S. S., Knop, F. K. & Thomsen, K. L., 1 Nov 2019, In : Liver international : official journal of the International Association for the Study of the Liver. 39, 11, p. 2094-2101 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. E-pub ahead of print
  10. E-pub ahead of print

    Glucose-dependent insulinotropic polypeptide is a pancreatic polypeptide secretagogue in humans

    Veedfald, S., Vedtofte, L., Skov-Jeppesen, K., Deacon, C. F., Hartmann, B., Vilsbøll, T., Knop, F. K., Christensen, M. B. & Holst, J. J., 26 Oct 2019, In : The Journal of clinical endocrinology and metabolism.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. E-pub ahead of print

    Gluco-metabolic effects of pharmacotherapy-induced modulation of bile acid physiology

    Brønden, A. & Knop, F. K., 20 Oct 2019, In : The Journal of clinical endocrinology and metabolism.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. E-pub ahead of print
  13. E-pub ahead of print

    GIP's effect on bone metabolism is reduced by the selective GIP receptor antagonist GIP(3-30)NH2

    Gasbjerg, L. S., Hartmann, B., Christensen, M. B., Lanng, A. R., Vilsbøll, T., Jørgensen, N. R., Holst, J. J., Rosenkilde, M. M. & Knop, F. K., 14 Oct 2019, In : The Bone. p. 115079

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The Liver-α-Cell Axis and Type 2 Diabetes

    Wewer Albrechtsen, N. J., Pedersen, J., Galsgaard, K. D., Winther-Sørensen, M., Suppli, M. P., Janah, L., Gromada, J., Vilstrup, H., Knop, F. K. & Holst, J. J., 1 Oct 2019, In : Endocrine Reviews. 40, 5, p. 1353-1366 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Evaluation of clinical translatability of the diet-induced obese and biopsy-confirmed gubra amylin mouse model of non-alcoholic steatohepatitis

    Rigbolt, K. T. G., Veidal, S., Suppli, M. P., Eriksen, P. L., Feigh, M., Knop, F. K., Gronbaek, H., Thomsen, K. L., Jelsing, J. & Vrang, N., Oct 2019, In : Hepatology. 70, Suppl 1, p. 1320-1321 1 p., 2241.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  16. Published

    Gluco-metabolic effects of oral and intravenous alcohol administration in men

    Lanng, A. R. R., Gasbjerg, L. S., Bergmann, N. C., Bermann, S., Helsted, M. M., Gillum, M. P., Hartmann, B., Holst, J. J., Vilsbøll, T. & Knop, F. K., Oct 2019, In : Endocrine Connections. 8, 10, p. 1372–1382 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Non‐Alcoholic Fatty Liver Disease Alters Expression Of Genes Governing Hepatic Nitrogen Conversion

    Eriksen, P. L., von Arenstorff Vilstrup, H., Rigbolt, K. T. G., Suppli, M. P., Sørensen, M., Veidal, S. S., Knop, F. K. & Thomsen, K. L., Oct 2019, In : Hepatology. 70, Suppl 1, p. 1351 1 p., 2297.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  18. E-pub ahead of print
  19. Published

    Endogenous glucose-dependent insulinotropic polypeptide exerts diverging and tissue specific in obese patients with type 2 diabetes

    Stensen, S., Gasbjerg, L. S., Krogh, L. L., Sparre-Ulrich, A. H., Jensen, M. H., Hartmann, B., Vilsbøll, T., Holst, J. J., Rosenkilde, M. M., Christensen, M. B. & Knop, F. K., Sep 2019, In : Diabetologia. 62, Suppl 1, p. 270 1 p., 560.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  20. Published

    Gut-derived glucagon in man

    Baekdal, M., Lund, A., Wewer Albrechtsen, N. J., Egholk, J., Jorsal, T., Black-Juel, C. T., Hunt, J., Galsgaard, K. D., Rigbolt, K., Palnæs, C., Orskov, C., Poulsen, S. S., Holst, J. J., Vilsbøll, T. & Knop, F. K., Sep 2019, In : Diabetologia. 62, Suppl 1, p. 231 1 p., 472.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  21. Published

    The glucagon-like peptide-1 receptor agonist, liraglutide, does not suppress postprandial cholecystokinin in patients with type 1 diabetes

    Johansen, N. J., Dejgaard, T. F., Frandsen, C. S., Lund, A., Knop, F. K., Rehfeld, J. F., Madsbad, S. & Andersen, H. U., Sep 2019, In : Diabetologia. 62, Suppl 1, p. 377 1 p., 780.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  22. Published

    The role of glucagon-like peptide 1 for the postprandial effects of metformin in type 2 diabetes

    Hansen, L. S., Gasbjerg, L. S., Brønden, A., Dalsgaard, N. B., Bahne, E., Stensen, S., Hellmann, P. H., J, R., Holst, J. J., Vilsbøll, T. & Knop, F. K., Sep 2019, In : Diabetologia. 62, Suppl 1, p. 57 1 p., 110.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  23. Published
  24. Published

    Remission of bile acid malabsorption symptoms following treatment with the glucagon-like peptide 1 receptor agonist liraglutide

    Kårhus, M. L., Brønden, A., Røder, M. E., Leotta, S., Sonne, D. P. & Knop, F. K., 1 Aug 2019, In : Gastroenterology. 157, 2, p. 569-571 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Clinical characteristics and glucose-lowering drug utilization among patients initiating liraglutide in Denmark: a routine clinical care prescription study

    Knudsen, J. S., Thomsen, R. W., Pottegård, A., Knop, F. K. & Sørensen, H. T., Aug 2019, In : Journal of Diabetes. 11, 8, p. 690-694 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  26. Published

    Glucagon Receptor Signaling and Glucagon Resistance

    Janah, L., Kjeldsen, S., Galsgaard, K. D., Winther-Sørensen, M., Stojanovska, E., Pedersen, J., Knop, F. K., Holst, J. J. & Wewer Albrechtsen, N. J., 5 Jul 2019, In : International Journal of Molecular Sciences. 20, 13, p. 3314 3314.

    Research output: Contribution to journalReviewResearchpeer-review

  27. Published

    New avenues in the regulation of gallbladder motility - implications for the use of glucagon-like peptide-derived drugs

    Gether, I. M., Nexøe-Larsen, C. & Knop, F. K., 1 Jul 2019, In : The Journal of clinical endocrinology and metabolism. 104, 7, p. 2463-2472 10 p., jcem_201801008.

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    A role for exogenous GLP-1 in the management of postprandial hypoglycaemia after Roux-en-Y gastric bypass?

    Øhrstrøm, C. C. & Knop, F. K., Jul 2019, In : European Journal of Endocrinology. 181, 3, p. 5-8 4 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  29. Published

    Continuous glucose monitoring in pregnant women with type 1 diabetes: an observational cohort study of 186 pregnancies

    Kristensen, K., Ögge, L. E., Sengpiel, V., Kjölhede, K., Dotevall, A., Elfvin, A., Knop, F. K., Wiberg, N., Katsarou, A., Shaat, N., Kristensen, L. & Berntorp, K., Jul 2019, In : Diabetologia. 62, 7, p. 1143-1153 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published
  31. Published

    Separate and Combined Effects of GIP and GLP-1 Infusions on Bone Metabolism in Overweight Men without Diabetes

    Bergmann, N. C., Lund, A., Gasbjerg, L. S., Jørgensen, N. R., Jessen, L., Hartmann, B., Holst, J. J., Christensen, M. B., Vilsbøll, T. & Knop, F. K., Jul 2019, In : The Journal of clinical endocrinology and metabolism. 104, 7, p. 2953-2960 8 p., jcem_201900008.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Lean women with polycystic ovary syndrome and insulin resistance have normal incretin effect, which is unaffected by metformin therapy

    Vedtofte, L., Foghsgaard, S., Zierau, L., Vilsbøll, T. & Knop, F. K., 12 Jun 2019. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  33. Published

    GIP and GLP-1 Potentiate Sulfonylurea-Induced Insulin Secretion in HNF1A-diabetes

    Christensen, A. S., Hædersdal, S., Rose, K., Hansen, N. L., Holst, J. J., Hansen, T., Knop, F. K. & Vilsbøll, T., 6 Jun 2019, In : Diabetes. 68, Suppl 1, 1 p., 981-P.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  34. Published

    Association Between Topical Corticosteroid Use and Type 2 Diabetes in Two European Population-Based Adult Cohorts

    Andersen, Y. M. F., Egeberg, A., Ban, L., Gran, S., Williams, H. C., Francis, N. A., Knop, F. K., Gislason, G. H., Skov, L. & Thyssen, J. P., 1 Jun 2019, In : Diabetes Care. 42, 6, p. 1095-1103 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published
  36. Published

    Separate and Combined Gluco-Metabolic Effects of Endogenous Glucose-Dependent Insulinotropic Polypeptide and Glucagon-Like Peptide-1 in Healthy Individuals

    Gasbjerg, L. S., Helsted, M. M., Hartmann, B., Jensen, M. H., Gabe, M. B. N., Sparre-Ulrich, A. H., Veedfald, S., Stensen, S., Lanng, A. R., Bergmann, N. C., Christensen, M. B., Vilsbøll, T., Holst, J. J., Rosenkilde, M. M. & Knop, F. K., May 2019, In : Diabetes. 68, 5, p. 906-917 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Liraglutide-Induced Weight Loss May be Affected by Autonomic Regulation in Type 1 Diabetes

    Hansen, C. S., Frandsen, C. S., Fleischer, J., Vistisen, D., Holst, J. J., Tarnow, L., Knop, F. K., Madsbad, S., Andersen, H. U. & Dejgaard, T. F., 12 Apr 2019, In : Frontiers in Endocrinology. 10, APR, p. 1-9 9 p., 242.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published
  39. Published

    Effects of combined GIP and GLP-1 infusion on energy intake, appetite and energy expenditure in overweight/obese individuals: a randomised, crossover study

    Bergmann, N. C., Lund, A., Gasbjerg, L. S., Meessen, E. C. E., Andersen, M. M., Bergmann, S., Hartmann, B., Holst, J. J., Jessen, L., Christensen, M. B., Vilsbøll, T. & Knop, F. K., 1 Apr 2019, In : Diabetologia. 62, 4, p. 665-675 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Hepatic transcriptome signatures in patients with varying degrees of nonalcoholic fatty liver disease compared with healthy normal-weight individuals

    Suppli, M. P., Rigbolt, K. T. G., Veidal, S. S., Heebøl, S., Lykke Eriksen, P., Demant, M., Bagger, J. I., Nielsen, J. C., Oró, D., Thrane, S. W., Lund, A., Strandberg, C., Kønig, M. J., Vilsbøll, T., Vrang, N., Thomsen, K. L., Grønbæk, H., Jelsing, J., Hansen, H. H. & Knop, F. K., 1 Apr 2019, In : American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 4, p. G462-G472

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Clinical translatability of a diet-induced obese mouse model of non-alcoholic steatohepatitis

    Rigbolt, K., Veidal, S. S., Suppli, M. P., Eriksen, P. L., Feigh, M., Knop, F. K., Gronbaek, H., Thomsen, K. L., Jelsing, J. & Vrang, N., Apr 2019, In : Journal of Hepatology. 70, Suppl 1, p. 544 1 p., FRI-339 .

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  42. Published

    Effect of the glucagon-like peptide-1 receptor agonist exenatide on bone status in obese, non-diabetic, antipsychotic-treated schizophrenia spectrum patients

    Eriksson, R., Broberg, B. V., Ishøy, P. L., Bak, N., Andersen, U. B., Jorgensen, N. R., Knop, F. K. & Ebdrup, B., Apr 2019, In : Schizophrenia Bulletin. 45, Suppl 2, p. 198 1 p., O12.4.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  43. Published

    Glucagon Receptor Signaling and Lipid Metabolism

    Galsgaard, K. D., Pedersen, J., Knop, F. K., Holst, J. J. & Wewer Albrechtsen, N. J., Apr 2019, In : Frontiers in physiology. 10, APR, p. 1-11 11 p., 413.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published
  45. Published
  46. Published

    Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease

    Niu, L., Geyer, P. E., Wewer Albrechtsen, N. J., Gluud, L. L., Santos, A., Doll, S., Treit, P. V., Holst, J. J., Knop, F. K., Vilsbøll, T., Junker, A., Sachs, S., Stemmer, K., Müller, T. D., Tschöp, M. H., Hofmann, S. M. & Mann, M., 1 Mar 2019, In : Molecular Systems Biology. 15, 3, 16 p., e8793.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Bariatric surgery in patients with non-alcoholic fatty liver disease - from pathophysiology to clinical effects

    Laursen, T. L., Hagemann, C. A., Wei, C., Kazankov, K., Thomsen, K. L., Knop, F. K. & Grønbæk, H., 27 Feb 2019, In : World Journal of Hepatology. 11, 2, p. 138-149 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Glucagon-like peptide-1 receptor-agonists for antipsychotic-associated cardio-metabolic risk factors: a systematic review and individual participant data meta-analysis

    Siskind, D., Hahn, M., Correll, C. U., Fink-Jensen, A., Russell, A. W., Bak, N., Broberg, B. V., Larsen, J., Ishøy, P. L., Vilsbøll, T., Knop, F. K., Kisely, S. & Ebdrup, B. H., 1 Feb 2019, In : Diabetes, Obesity and Metabolism. 21, 2, p. 293-302 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Glucose metabolism in patients with psoriasis

    Friis, N. U., Hoffmann, N., Gyldenløve, M., Skov, L., Vilsbøll, T., Knop, F. K. & Storgaard, H., 1 Feb 2019, In : British Journal of Dermatology. 180, 2, p. 264-271 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  50. Published
  51. Published

    Extrapancreatic glucagon: present status

    Lund, A. & Knop, F. K., 1 Jan 2019, In : Diabetes Research and Clinical Practice. 147, p. 19-28 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

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