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The Capital Region of Denmark - a part of Copenhagen University Hospital
Filip Krag Knop

Filip Krag Knop

Chief Consultant

Niels Steensens Vej 2-4

2820 Gentofte

Denmark

​Gentofte Hospital

Building: Opgang ​7, 3. sal, Kildegårdsvej 28

2900 Hellerup

Denmark

  1. 2019
  2. Published
  3. Published

    Clinical characteristics and glucose-lowering drug utilization among patients initiating liraglutide in Denmark: a routine clinical care prescription study

    Knudsen, J. S., Thomsen, R. W., Pottegård, A., Knop, F. K. & Sørensen, H. T., Aug 2019, In : Journal of Diabetes. 11, 8, p. 690-694 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  4. Published

    Glucagon Receptor Signaling and Glucagon Resistance

    Janah, L., Kjeldsen, S., Galsgaard, K. D., Winther-Sørensen, M., Stojanovska, E., Pedersen, J., Knop, F. K., Holst, J. J. & Wewer Albrechtsen, N. J., 5 Jul 2019, In : International Journal of Molecular Sciences. 20, 13, p. 3314

    Research output: Contribution to journalReviewResearchpeer-review

  5. E-pub ahead of print

    Investigating Intestinal Glucagon after Roux-en-Y Gastric Bypass Surgery

    Jorsal, T., Wewer Albrechtsen, N. J., Christensen, M. M., Mortensen, B., Wandall, E., Langholz, E., Friis, S., Worm, D., Ørskov, C., Støving, R. K., Andries, A., Juhl, C. B., Sørensen, F., Forman, J. L., Falkenhahn, M., Musholt, P. B., Theis, S., Larsen, P. J., Holst, J. J., Vrang, N., Jelsing, J., Vilsbøll, T. & Knop, F. K., 5 Jul 2019, In : The Journal of clinical endocrinology and metabolism.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Continuous glucose monitoring in pregnant women with type 1 diabetes: an observational cohort study of 186 pregnancies

    Kristensen, K., Ögge, L. E., Sengpiel, V., Kjölhede, K., Dotevall, A., Elfvin, A., Knop, F. K., Wiberg, N., Katsarou, A., Shaat, N., Kristensen, L. & Berntorp, K., Jul 2019, In : Diabetologia. 62, 7, p. 1143-1153 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published
  8. Published

    Separate and Combined Effects of GIP and GLP-1 Infusions on Bone Metabolism in Overweight Men without Diabetes

    Bergmann, N. C., Lund, A., Gasbjerg, L. S., Jørgensen, N. R., Jessen, L., Hartmann, B., Holst, J. J., Christensen, M. B., Vilsbøll, T. & Knop, F. K., Jul 2019, In : The Journal of clinical endocrinology and metabolism. 104, 7, p. 2953-2960 8 p., jcem_201900008.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Lean women with polycystic ovary syndrome and insulin resistance have normal incretin effect, which is unaffected by metformin therapy

    Vedtofte, L., Foghsgaard, S., Zierau, L., Vilsbøll, T. & Knop, F. K., 12 Jun 2019. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  10. Published

    GIP and GLP-1 Potentiate Sulfonylurea-Induced Insulin Secretion in HNF1A-diabetes

    Christensen, A. S., Hædersdal, S., Rose, K., Hansen, N. L., Holst, J. J., Hansen, T., Knop, F. K. & Vilsbøll, T., 6 Jun 2019, In : Diabetes. 68, Suppl 1, 1 p., 981-P.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  11. Published

    Association Between Topical Corticosteroid Use and Type 2 Diabetes in Two European Population-Based Adult Cohorts

    Andersen, Y. M. F., Egeberg, A., Ban, L., Gran, S., Williams, H. C., Francis, N. A., Knop, F. K., Gislason, G. H., Skov, L. & Thyssen, J. P., 1 Jun 2019, In : Diabetes Care. 42, 6, p. 1095-1103 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published
  13. Published

    Separate and Combined Gluco-Metabolic Effects of Endogenous Glucose-Dependent Insulinotropic Polypeptide and Glucagon-Like Peptide-1 in Healthy Individuals

    Gasbjerg, L. S., Helsted, M. M., Hartmann, B., Jensen, M. H., Gabe, M. B. N., Sparre-Ulrich, A. H., Veedfald, S., Stensen, S., Lanng, A. R., Bergmann, N. C., Christensen, M. B., Vilsbøll, T., Holst, J. J., Rosenkilde, M. M. & Knop, F. K., May 2019, In : Diabetes. 68, 5, p. 906-917 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Liraglutide-Induced Weight Loss May be Affected by Autonomic Regulation in Type 1 Diabetes

    Hansen, C. S., Frandsen, C. S., Fleischer, J., Vistisen, D., Holst, J. J., Tarnow, L., Knop, F. K., Madsbad, S., Andersen, H. U. & Dejgaard, T. F., 12 Apr 2019, In : Frontiers in Endocrinology. 10, APR, p. 1-9 9 p., 242.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. E-pub ahead of print
  16. Published
  17. Published

    Effects of combined GIP and GLP-1 infusion on energy intake, appetite and energy expenditure in overweight/obese individuals: a randomised, crossover study

    Bergmann, N. C., Lund, A., Gasbjerg, L. S., Meessen, E. C. E., Andersen, M. M., Bergmann, S., Hartmann, B., Holst, J. J., Jessen, L., Christensen, M. B., Vilsbøll, T. & Knop, F. K., 1 Apr 2019, In : Diabetologia. 62, 4, p. 665-675 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Hepatic transcriptome signatures in patients with varying degrees of nonalcoholic fatty liver disease compared with healthy normal-weight individuals

    Suppli, M. P., Rigbolt, K. T. G., Veidal, S. S., Heebøl, S., Lykke Eriksen, P., Demant, M., Bagger, J. I., Nielsen, J. C., Oró, D., Thrane, S. W., Lund, A., Strandberg, C., Kønig, M. J., Vilsbøll, T., Vrang, N., Thomsen, K. L., Grønbæk, H., Jelsing, J., Hansen, H. H. & Knop, F. K., 1 Apr 2019, In : American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 4, p. G462-G472

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Glucagon Receptor Signaling and Lipid Metabolism

    Galsgaard, K. D., Pedersen, J., Knop, F. K., Holst, J. J. & Wewer Albrechtsen, N. J., Apr 2019, In : Frontiers in physiology. 10, APR, p. 1-11 11 p., 413.

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published
  21. E-pub ahead of print

    The liver-alpha cell axis and type 2 diabetes

    Wewer Albrechtsen, N. J., Pedersen, J., Galsgaard, K. D., Winther-Sørensen, M., Suppli, M. P., Janah, L., Gromada, J., Vilstrup, H., Knop, F. K. & Holst, J. J., 28 Mar 2019, In : Endocrine Reviews.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published
  23. E-pub ahead of print

    Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease

    Niu, L., Geyer, P. E., Wewer Albrechtsen, N. J., Gluud, L. L., Santos, A., Doll, S., Treit, P. V., Holst, J. J., Knop, F. K., Vilsbøll, T., Junker, A., Sachs, S., Stemmer, K., Müller, T. D., Tschöp, M. H., Hofmann, S. M. & Mann, M., 1 Mar 2019, In : Molecular Systems Biology. 15, 3, p. e8793

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Bariatric surgery in patients with non-alcoholic fatty liver disease - from pathophysiology to clinical effects

    Laursen, T. L., Hagemann, C. A., Wei, C., Kazankov, K., Thomsen, K. L., Knop, F. K. & Grønbæk, H., 27 Feb 2019, In : World Journal of Hepatology. 11, 2, p. 138-149 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published
  26. Published
  27. Published
  28. 2018
  29. Published

    Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes

    Bahne, E., Sun, E. W. L., Young, R. L., Hansen, M., Sonne, D. P., Hansen, J. S., Rohde, U., Liou, A. P., Jackson, M. L., de Fontgalland, D., Rabbitt, P., Hollington, P., Sposato, L., Due, S., Wattchow, D. A., Rehfeld, J. F., Holst, J. J., Keating, D. J., Vilsbøll, T. & Knop, F. K., 6 Dec 2018, In : JCI Insight. 3, 23, p. 93936

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Response to: Letter to the Editor: Hemodynamic Effects of Glucagon - A literature Review

    Meidahl Petersen, K., Bøgevig, S., Holst, J. J., Knop, F. K. & Christensen, M. B., 1 Dec 2018, In : The Journal of clinical endocrinology and metabolism. 103, 12, p. 4480–4481 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  31. Published
  32. Published
  33. Published

    Changes in urinary excretion of oxidative nucleic acid modifications in the week following Copenhagen Marathon 2018, Denmark

    Larsen, E. L., Kjaer, L. K., Michaelsen, C., Andersen, E., Lyngbaek, M., Petersen-Bonding, C., Henriksen, T., Vilsboll, T., Knop, F. K., Ploug, T., Poulsen, H. E. & Karstoft, K., 20 Nov 2018, In : Free Radical Biology and Medicine. 128, 1, p. S54

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  34. Published

    Future Perspectives on GLP-1 Receptor Agonists and GLP-1/glucagon Receptor Co-agonists in the Treatment of NAFLD

    Seghieri, M., Christensen, A. S., Andersen, A., Solini, A., Knop, F. K. & Vilsbøll, T., 6 Nov 2018, In : Frontiers in Endocrinology. 9, p. 649

    Research output: Contribution to journalReviewResearchpeer-review

  35. Published

    Effects of liraglutide on gallbladder emptying: a randomised, placebo-controlled trial in adults with overweight or obesity

    Nexøe-Larsen, C. C., Sørensen, P. H., Hausner, H., Agersnap, M., Baekdal, M., Brønden, A., Gustafsson, L. N., Sonne, D. P., Vedtofte, L., Vilsbøll, T. & Knop, F. K., Nov 2018, In : Diabetes, Obesity and Metabolism Online. 20, 11, p. 2557-2564 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Recovery of gut microbiota of healthy adults following antibiotic exposure

    Palleja, A., Mikkelsen, K. H., Forslund, S. K., Kashani, A., Allin, K. H., Nielsen, T., Hansen, T. H., Liang, S., Feng, Q., Zhang, C., Pyl, P. T., Coelho, L. P., Yang, H., Wang, J., Typas, A., Nielsen, M. F., Nielsen, H. B., Bork, P., Wang, J., Vilsbøll, T., Hansen, T., Knop, F. K., Arumugam, M. & Pedersen, O., Nov 2018, In : Nature Microbiology. 3, 11, p. 1255-1265 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published
  38. Published

    Diverse hepatic microbial DNA fingerprints in healthy lean and obese steatotic humans

    Bagger, J. I., Suppli, M. P., Nielsen, T., Lelouvier, B., Broha, A., Demant, M. G., Kønig, M. J., Strandberg, C., Lund, A., Vilsbøll, T. & Knop, F. K., 2 Oct 2018, In : Diabetologia. 61, supll 1, p. S120-S121 1 p., 236.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  39. Published

    High intensity interval training improves insulin sensitivity in individuals with prediabetes

    Mensberg, P., Frandsen, C., Espersen, E., Leineweber, T., Storgaard, H., Schlawitz, K., Petersen, T., Poulsen, J., Sørensen, F., Forman, J., Knop, F. K. & Vilsbøll, T., 1 Oct 2018, In : Diabetologia. 61, Suppl 1, p. S217-S218 1 p., 441.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  40. Published

    Individual and combined glucose-lowering effects of glucagon receptor antagonism and dipeptidyl peptidase-4 inhibition

    Maagensen, H., Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Holst, J. J., Knop, F. K. & Vilsbøll, T., 1 Oct 2018, In : Diabetologia. 61, suppl 1, p. S246-S247 1 p., 504.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  41. Published

    Individual and combined glucose-lowering effects of glucagon receptor antagonism and sodium-glucose cotransporter 2 inhibition

    Hædersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Holst, J. J., Knop, F. K. & Vilsbøll, T., 1 Oct 2018, In : Diabetologia. 61, Suppl 1, p. S312-S312 1 p., 642.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  42. Published

    Metabolomics reveal changes in plasma concentrations of 3-hydroxybutyric acid, citric acid, oleic acid and proline in gestational diabetes

    Johansen, N. J., Demant, M. G., Suvitaival, T., Trošt, K., Ahonen, L. L., Bonde, L., Svare, J., Quigley, C., Vilsbøll, T. & Knop, F. K., 1 Oct 2018, In : Diabetologia. 61, Suppl 1, p. S252-S252 1 p., 514.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  43. Published

    Mono- and co-activation of the GIP and GLP-1 receptors inhibits bone resorption

    Bergmann, N., Lund, A., Heimbürger, S. M., Gasbjerg, L. S., Jørgensen, N. R., Jessen, L., Hartmann, B., Holst, J. J., Christensen, M., Vilsbøll, T. & Knop, F. K., 1 Oct 2018, In : Diabetologia. 61, suppl 1, p. S348-S348 1 p., 717.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  44. Published

    More subjects achieved composite reductions of ≥1% HbA1c, ≥5% body weight and ≥5 mmHg SBP with semaglutide vs comparators across the SUSTAIN 1-5 and 7 trials

    Dungan, K., Aroda, V. R., Knop, F. K., Leiter, L. A., Lausvig, N., Lindberg, S., Ferløv Schwensen, J. & Meier, J., 1 Oct 2018, In : Diabetologia. 61, suppl1, p. S359-S360 1 p., 738.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  45. Published

    Novel Biomarker Discovery in Non-Alcoholic Steatohepatitis (NASH): Translation of Complex Data into Clear Results

    Veidal, S., Rigbolt, K., Petersen, P. S., Suppli, M., Bagger, J. I., Lund, A., Heeboll, S., Gronbaek, H., Vilsboll, T., Knop, F. K., Vrang, N. & Jelsing, J., 1 Oct 2018, In : Hepatology. 68, 1, p. 1013A

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  46. Published

    Postprandial effects of individual and combined GIP and GLP-1 receptor antagonism in healthy subjects

    Gasbjerg, L. S., Helsted, M. M., Sparre-Ulrich, A. H., Lanng, A. R., Stensen, S., Jakobsen, M. H., Hartmann, B., Christensen, M., Holst, J. J., Vilsbøll, T., Rosenkilde, M. M. & Knop, F. K., 1 Oct 2018, In : Diabetologia. 61, suppl 1, p. S246-S246 1 p., 503.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  47. Published

    The effect of Roux-en-Y gastric bypass surgery on the gut mucosal gene expression profile and circulating gut hormones

    Christensen, M. M., Jorsal, T., Mortensen, B., Wandall, E. P., Langholz, E., Friis, S. U., Worm, D., Støving, R. K., Aldries, A., Juhl, C. B., Rehfeld, J. F., Vrang, N., Jelsing, J., Vilsbøll, T. & Knop, F. K., 1 Oct 2018, In : Diabetologia. 61, Suppl 1, p. S248-S249 1 p., 508.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  48. Published

    The role of the incretins in the postprandial bone remodelling

    Helsted, M. M., Gasbjerg, L. S., Lanng, A. R., Stensen, S., Hartmann, B., Christensen, M., Holst, J. J., Vilsbøll, T., Rosenkilde, M. & Knop, F. K., 1 Oct 2018, In : Diabetologia. 61, Suppl 1, p. S221-S221 1 p., 449.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  49. Published

    Preclinical discovery and development of colesevelam for the treatment of type 2 diabetes

    Nerild, H. H., Christensen, M. B., Knop, F. K. & Brønden, A., Oct 2018, In : Expert Opinion on Drug Discovery. 13, 12, p. 1161-1167 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. E-pub ahead of print
  51. Published

    No changes in levels of bone formation and resorption markers following a broad-spectrum antibiotic course

    Mikkelsen, K. H., Vilsbøll, T., Holst, J. J., Hartmann, B., Knop, F. K. & Frost, M., 4 Sep 2018, In : BMC Endocrine Disorders. 18, 1, p. 60

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Differences Between Randomized Clinical Trial Patients and Real-World Initiators of the Glucagon-Like Peptide 1 Receptor Agonist Liraglutide

    Knudsen, J. S., Thomsen, R. W., Pottegård, A., Knop, F. K. & Sørensen, H. T., Sep 2018, In : Diabetes Care. 41, 9, p. e133-e135 2 p.

    Research output: Contribution to journalLetterResearchpeer-review

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