Research output per year
Research output per year
Personal profile
Expertises
In specialist training to become a medical oncologist, PhD student in neuro oncology
Main research areas
Brain tumors; glioblastomas; next generation sequencing (NGS); tumor profiling; precision medicine
Current research
Enrolled as PhD-student April 1st 2016. PhD-project with the tiltle "Development and evaluation of precision medicine in patients with brain cancer WHO grade IV glioblastoma (GBM)".
Aims and objectives
1) To determine the genetic tumor profile in GBM
2) To investigate the prevalence of specific molecular and possible targetable abnormalities in patients with GBM
3) To investigate treatment-related changes in the genetic profile in order to identify possible mechanisms of resistance to standard therapy (when having second surgery for recurrence).
4) To establish and develop precision medicine based upon the genetic tumor profile
4a) Include patients with relevant genetic tumor profile in protocols with precision medicine
4b) To evaluate the effect of the precision medicine
Potential conflicts of interest
Subinvestigator in one phase 2 and one phase 3 immuno protocol for patients with primary GBM, sponsored by BMS (CheckMate 209-498 and 209-548)
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Early, Patient-Centered, and Multidisciplinary Approach in Newly Diagnosed Multiple Myeloma: What Are We Talking About? A Case Description and Discussion
Sørensen, J., Sørensen, T. V., Andersen, K. H., Nørøxe, D. S. & Mylin, A. K., 4 Jan 2022, In: Palliative Medicine Reports. 3, 1, p. 369-373 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tumor mutational burden and purity adjustment before and after treatment with temozolomide in 27 paired samples of glioblastoma; a prospective study
Schou Nørøxe, D., Flynn, A., Yde, C. W., Østrup, O., Nielsen, F. C., Skjøth-Rasmussen, J., Brennum, J., Hamerlik, P., Weischenfeldt, J., Poulsen, H. S. & Lassen, U., Jan 2022, In: Molecular Oncology. 16, 1, p. 206-218 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
Genomic profiling of newly diagnosed glioblastoma patients and its potential for clinical utility - a prospective, translational study
Nørøxe, D. S., Yde, C. W., Østrup, O., Michaelsen, S. R., Schmidt, A. Y., Kinalis, S., Torp, M. H., Skjøth-Rasmussen, J., Brennum, J., Hamerlik, P., Poulsen, H. S., Nielsen, F. C. & Lassen, U., Nov 2020, In: Molecular Oncology. 14, 11, p. 2727-2743 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
8 Citations (Scopus) -
Cell-free DNA in newly diagnosed patients with glioblastoma - a clinical prospective feasibility study
Nørøxe, D. S., Østrup, O., Yde, C. W., Ahlborn, L. B., Nielsen, F. C., Michaelsen, S. R., Larsen, V. A., Skjøth-Rasmussen, J., Brennum, J., Hamerlik, P., Poulsen, H. S. & Lassen, U., 8 Jul 2019, In: Oncotarget. 10, 43, p. 4397-4406 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Extracranial metastases in glioblastoma-Two case stories
Schou Nørøxe, D., Regner Michaelsen, S., Broholm, H., Møller, S., Skovgaard Poulsen, H. & Lassen, U., 2019, In: Clinical Case Reports. 7, 2, p. 289-294 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
5 Citations (Scopus)