Research output per year
Research output per year
Personal profile
Expertises
In specialist training to become a medical oncologist, PhD student in neuro oncology
Main research areas
Brain tumors; glioblastomas; next generation sequencing (NGS); tumor profiling; precision medicine
Current research
Enrolled as PhD-student April 1st 2016. PhD-project with the tiltle "Development and evaluation of precision medicine in patients with brain cancer WHO grade IV glioblastoma (GBM)".
Aims and objectives
1) To determine the genetic tumor profile in GBM
2) To investigate the prevalence of specific molecular and possible targetable abnormalities in patients with GBM
3) To investigate treatment-related changes in the genetic profile in order to identify possible mechanisms of resistance to standard therapy (when having second surgery for recurrence).
4) To establish and develop precision medicine based upon the genetic tumor profile
4a) Include patients with relevant genetic tumor profile in protocols with precision medicine
4b) To evaluate the effect of the precision medicine
Potential conflicts of interest
Subinvestigator in one phase 2 and one phase 3 immuno protocol for patients with primary GBM, sponsored by BMS (CheckMate 209-498 and 209-548)
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Actionable alterations in glioblastoma: Insights from the implementation of genomic profiling as the standard of care from 2016 to 2023
Fougner, V., Urup, T., Poulsen, H. S., Grunnet, K., Westmose, C. Y., Melchior, L. C., Larsen, K. B., Højgaard, M., Spanggaard, I., Belcaid, L., Rohrberg, K. S., Lassen, U., Hasselbalch, B. & Nørøxe, D. S., Feb 2025, In: Neuro-Oncology Practice. 12, 1, p. 34-44 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
Clinico-pathological characteristics and treatment outcome in non-small cell lung cancer in Greenland 2015-2020 - a comparison with the cohort from 2004 to 2010
Nørøxe, D. S., Frandsen, S., Clausen, M. M., Hansen, T. I., Geisler, U. W., Petersen, A. J. & Langer, S., 17 Dec 2024, In: Acta Oncologica. 63, p. 958-964 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glioblastoma cells increase expression of notch signaling and synaptic genes within infiltrated brain tissue
Harwood, D. S. L., Pedersen, V., Bager, N. S., Schmidt, A. Y., Stannius, T. O., Areškevičiūtė, A., Josefsen, K., Nørøxe, D. S., Scheie, D., Rostalski, H., Lü, M. J. S., Locallo, A., Lassen, U., Bagger, F. O., Weischenfeldt, J., Heiland, D. H., Vitting-Seerup, K., Michaelsen, S. R. & Kristensen, B. W., 9 Sept 2024, In: Nature Communications. 15, 1, 7857.Research output: Contribution to journal › Journal article › Research › peer-review
6 Citations (Scopus) -
Ultra-low-dose radiation for gastric MALT lymphoma
Petersen, P. M. & Nørøxe, D. S., Jul 2024, In: The Lancet. Haematology. 11, 7, p. e475-e476Research output: Contribution to journal › Comment/debate › Research › peer-review
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The Neurogenome study: Comprehensive molecular profiling to optimize treatment for Danish glioblastoma patients
Nørøxe, D. S., Maarup, S., Fougner, V., Muhic, A., Møller, S., Urup, T., Lü, M. J. S., Weischenfeldt, J., Hansen, A. E., Skovgaard Poulsen, H., Lassen, U. & Hasselbalch, B., 2023, In: Neuro-Oncology Advances. 5, 1, vdad137.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus)