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The Capital Region of Denmark - a part of Copenhagen University Hospital

Daniel Hargbøl Madsen

Herlev Hospital, Herlev Ringvej 75

Building: 81-05-PV9

2730 Herlev

Denmark

  1. 2021
  2. E-pub ahead of print

    Arginase 1-based immune modulatory vaccines induce anti-cancer immunity and synergize with anti-PD-1 checkpoint blockade

    Aaboe Jørgensen, M., Ugel, S., Hübbe, M. L., Carretta, M., Perez-Penco, M., Weis-Banke, S. E., Martinenaite, E., Kopp, K., Chapellier, M., Adamo, A., De Sanctis, F., Frusteri, C., Iezzi, M., Zocca, M-B., Madsen, D. H., Pedersen, A. W., Bronte, V. & Andersen, M. H., 13 Sep 2021, (E-pub ahead of print) In: Cancer immunology research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Loss of Ambra1 promotes melanoma growth and invasion

    Di Leo, L., Bodemeyer, V., Bosisio, F. M., Claps, G., Carretta, M., Rizza, S., Faienza, F., Frias, A., Khan, S., Bordi, M., Pacheco, M. P., Di Martino, J., Bravo-Cordero, J. J., Daniel, C. J., Sears, R. C., Donia, M., Madsen, D. H., Guldberg, P., Filomeni, G., Sauter, T., Robert, C., De Zio, D. & Cecconi, F., 5 May 2021, In: Nature Communications. 12, 1, p. 2550 2550.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2020
  5. Published

    Granzyme B Degraded Type IV Collagen Products in Serum Identify Melanoma Patients Responding to Immune Checkpoint Blockade

    Jensen, C., Sinkeviciute, D., Madsen, D. H., Önnerfjord, P., Hansen, M., Schmidt, H., Karsdal, M. A., Svane, I. M. & Willumsen, N., 28 Sep 2020, In: Cancers. 12, 10

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Collagen Density Modulates the Immunosuppressive Functions of Macrophages

    Larsen, A. M. H., Kuczek, D. E., Kalvisa, A., Siersbæk, M. S., Thorseth, M-L., Johansen, A. Z., Carretta, M., Grøntved, L., Vang, O. & Madsen, D. H., 1 Sep 2020, In: Journal of immunology (Baltimore, Md. : 1950). 205, 5, p. 1461-1472 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published
  8. Published

    Cellular uptake of collagens and implications for immune cell regulation in disease

    Jürgensen, H. J., van Putten, S., Nørregaard, K. S., Bugge, T. H., Engelholm, L. H., Behrendt, N. & Madsen, D. H., 25 Feb 2020, In: Cellular and molecular life sciences. 77, 16, p. 3161-3176 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  9. 2019
  10. Published

    Collagen density regulates the activity of tumor-infiltrating T cells

    Kuczek, D. E., Larsen, A. M. H., Thorseth, M-L., Carretta, M., Kalvisa, A., Siersbæk, M. S., Simões, A. M. C., Roslind, A., Engelholm, L. H., Noessner, E., Donia, M., Svane, I. M., Straten, P. T., Grøntved, L. & Madsen, D. H., 12 Mar 2019, In: Journal for ImmunoTherapy of Cancer. 7, 1, p. 68 68.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    CCL2/MCP-1 signaling drives extracellular matrix turnover by diverse macrophage subsets

    Jürgensen, H. J., Silva, L. M., Kriegslund, O., Van Putten, S., Madsen, D. H., Behrendt, N., Engelholm, L. H. & Bugge, T. H., Feb 2019, In: Matrix Biology Plus. 100003.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins

    Jürgensen, H. J., Nørregaard, K. S., Sibree, M. M., Santoni-Rugiu, E., Madsen, D. H., Wassilew, K., Krustrup, D., Garred, P., Bugge, T. H., Engelholm, L. H. & Behrendt, N., 7 Jan 2019, In: Journal of Cell Biology. 218, 1, p. 333-349 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2018
  14. Published

    Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients

    Jensen, C., Madsen, D. H., Hansen, M., Schmidt, H., Svane, I. M., Karsdal, M. A. & Willumsen, N., 19 Dec 2018, In: Journal for ImmunoTherapy of Cancer. 6, 1, p. 152

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2017
  16. Published

    Tumor-Associated Macrophages Derived from Circulating Inflammatory Monocytes Degrade Collagen through Cellular Uptake

    Madsen, D. H., Jürgensen, H. J., Siersbæk, M. S., Kuczek, D. E., Grey Cloud, L., Liu, S., Behrendt, N., Grøntved, L., Weigert, R. & Bugge, T. H., 26 Dec 2017, In: Cell Reports. 21, 13, p. 3662-3671 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2016
  18. Published

    Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice

    Fan, M-H., Zhu, Q., Li, H-H., Ra, H-J., Majumdar, S., Gulick, D. L., Jerome, J. A., Madsen, D. H., Christofidou-Solomidou, M., Speicher, D. W., Bachovchin, W. W., Feghali-Bostwick, C. & Puré, E., 8 Apr 2016, In: Journal of Biological Chemistry. 291, 15, p. 8070-89 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo

    Motley, M. P., Madsen, D. H., Jürgensen, H. J., Spencer, D. E., Szabo, R., Holmbeck, K., Flick, M. J., Lawrence, D. A., Castellino, F. J., Weigert, R. & Bugge, T. H., 3 Mar 2016, In: Blood. 127, 9, p. 1085-96 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published
  21. 2015
  22. Published

    The collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review)

    Carlsen Melander, E. M., Jürgensen, H. J., Madsen, D. H., Engelholm, L. H. & Behrendt, N., 12 Aug 2015, In: International Journal of Oncology. 47, 4, p. 1177-88

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin

    Friis, S., Madsen, D. H. & Bugge, T. H., Feb 2015, In: Journal of Biological Chemistry. 291, 6, p. :2577-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2014
  25. Published

    Complex Determinants in Specific Members of the Mannose Receptor Family Govern Collagen Endocytosis

    Jürgensen, H. J., Johansson, K. B. C., Madsen, D. H., Porse, A., Carlsen Melander, E. M., Nielsen, C., Sørensen, K. R., Bugge, T. H., Behrendt, N. & Engelholm, L. H., 14 Mar 2014, In: Journal of Biological Chemistry. p. 7935-7947

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2013
  27. Published

    M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway

    Madsen, D. H., Leonard, D., Masedunskas, A., Moyer, A., Jürgensen, H. J., Peters, D. E., Amornphimoltham, P., Selvaraj, A., Yamada, S. S., Brenner, D. A., Burgdorf, S., Engelholm, L. H., Behrendt, N., Holmbeck, K., Weigert, R. & Bugge, T. H., 16 Sep 2013, In: Journal of Cell Biology. 202, 6, p. 951-66 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP. Impact on lymphangiogenesis

    Ingvarsen, S., Porse, A., Erpicum, C., Maertens, L., Jürgensen, H. J., Madsen, D. H., Carlsen Melander, E. M., Gårdsvoll, H., Høyer-Hansen, G., Noel, A., Holmbeck, K., Engelholm, L. H. & Behrendt, N., 12 Apr 2013, In: Journal of Biological Chemistry. 288, 15, p. 10195-204

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Differential Actions of the Endocytic Collagen Receptor uPARAP/Endo180 and the Collagenase MMP-2 in Bone Homeostasis

    Madsen, D. H., Jürgensen, H. J., Ingvarsen, S., Carlsen Melander, E. M., Albrechtsen, R., Hald, A., Holmbeck, K., Bugge, T. H., Behrendt, N. & Engelholm, L. H., 2013, In: P L o S One. 8, 8, p. e71261

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2012
  31. Published

    Endocytic collagen degradation: A novel mechanism involved in the protection against liver fibrosis

    Madsen, D. H., Jürgensen, H. J., Ingvarsen, S., Carlsen Melander, E. M., Vainer, B., Egerod, K. L., Hald, A., Rønø, B., Madsen, M. C., Bugge, T. H., Engelholm, L. H. & Behrendt, N., May 2012, In: Journal of Pathology. 227, 1, p. 94-105

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published
  33. 2011
  34. Published
  35. Published
  36. Published

    The non-phagocytic route of collagen uptake: a distinct degradation pathway

    Madsen, D. H., Ingvarsen, S., Jürgensen, H. J., Melander, M. C., Kjøller, L., Moyer, A., Honoré, C., Madsen, M. C., Garred, P., Burgdorf, S., Bugge, T. H., Behrendt, N. & Engelholm, L. H., 2011, In: Journal of Biological Chemistry. 286, 30, p. 26996-7010 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2008
  38. Published
  39. Published
  40. 2007
  41. Published

    Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation

    Madsen, D. H., Engelholm, L. H., Ingvarsen, S., Hillig, T., Wagenaar-Miller, R. A., Kjøller, L., Gårdsvoll, H., Høyer-Hansen, G., Holmbeck, K., Bugge, T. H. & Behrendt, N., 14 Sep 2007, In: Journal of Biological Chemistry. 282, 37, p. 27037-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Increased expression of the collagen internalization receptor uPARAP/Endo180 in the stroma of head and neck cancer

    Sulek, J., Wagenaar-Miller, R. A., Shireman, J., Molinolo, A., Madsen, D. H., Engelholm, L. H., Behrendt, N. & Bugge, T. H., Apr 2007, In: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 55, 4, p. 347-53 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 6449