Ceramides and phospholipids are downregulated with liraglutide treatment: results from the LiraFlame randomized controlled trial

Zobel, E. H., Wretlind, A., Ripa, R. S., Rotbain Curovic, V., von Scholten, B. J., Suvitaival, T., Hansen, T. W., Kjær, A., Legido-Quigley, C. & Rossing, P., Sep 2021, In: BMJ open diabetes research & care. 9, 1, e002395.

Research output: Contribution to journal › Journal article › Research › peer-review

Distinct Molecular Signatures of Clinical Clusters in People with Type 2 Diabetes: an IMIRHAPSODY Study

Slieker, R. C., Donnelly, L. A., Fitipaldi, H., Bouland, G. A., Giordano, G. N., Åkerlund, M., Gerl, M. J., Ahlqvist, E., Ali, A., Dragan, I., Elders, P., Festa, A., Hansen, M. K., van der Heijden, A. A., Aly, D. M., Kim, M., Kuznetsov, D., Mehl, F., Klose, C., Simons, K., Pavo, I., Pullen, T. J., Suvitaival, T., Wretlind, A., Rossing, P., Lyssenko, V., Quigley, C. L., Groop, L., Thorens, B., Franks, P. W., Ibberson, M., Rutter, G. A., Beulens, J. W., 't Hart, L. M. & Pearson, E. R., 10 Aug 2021, (E-pub ahead of print) In: Diabetes.

Research output: Contribution to journal › Journal article › Research › peer-review

Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study

Slieker, R. C., Donnelly, L. A., Fitipaldi, H., Bouland, G. A., Giordano, G. N., Åkerlund, M., Gerl, M. J., Ahlqvist, E., Ali, A., Dragan, I., Festa, A., Hansen, M. K., Mansour Aly, D., Kim, M., Kuznetsov, D., Mehl, F., Klose, C., Simons, K., Pavo, I., Pullen, T. J., Suvitaival, T., Wretlind, A., Rossing, P., Lyssenko, V., Legido-Quigley, C., Groop, L., Thorens, B., Franks, P. W., Ibberson, M., Rutter, G. A., Beulens, J. W. J., 't Hart, L. M. & Pearson, E. R., 10 Jun 2021, (E-pub ahead of print) In: Diabetologia.

Research output: Contribution to journal › Journal article › Research › peer-review

Changes in the lipidome in type 1 diabetes following low carbohydrate diet: Post-hoc analysis of a randomized crossover trial

Al-Sari, N., Schmidt, S., Suvitaival, T., Kim, M., Trošt, K., Ranjan, A. G., Christensen, M. B., Overgaard, A. J., Pociot, F., Nørgaard, K. & Legido-Quigley, C., Apr 2021, In: Endocrinology, Diabetes & Metabolism. 4, 2, p. e00213 e00213.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association study of Alzheimer's disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset

Hong, S., Prokopenko, D., Dobricic, V., Kilpert, F., Bos, I., Vos, S. J. B., Tijms, B. M., Andreasson, U., Blennow, K., Vandenberghe, R., Cleynen, I., Gabel, S., Schaeverbeke, J., Scheltens, P., Teunissen, C. E., Niemantsverdriet, E., Engelborghs, S., Frisoni, G., Blin, O., Richardson, J. C., Bordet, R., Molinuevo, J. L., Rami, L., Kettunen, P., Wallin, A., Lleó, A., Sala, I., Popp, J., Peyratout, G., Martinez-Lage, P., Tainta, M., Dobson, R. J. B., Legido-Quigley, C., Sleegers, K., Van Broeckhoven, C., Ten Kate, M., Barkhof, F., Zetterberg, H., Lovestone, S., Streffer, J., Wittig, M., Franke, A., Tanzi, R. E., Visser, P. J., Bertram, L. & Alzheimer’s Disease Neuroimaging Initiative (ADNI), 22 Dec 2020, In: Translational psychiatry. 10, 1, p. 403 403.

Research output: Contribution to journal › Journal article › Research › peer-review

Gut microbiota profile and selected plasma metabolites in type 1 diabetes without and with stratification by albuminuria

Winther, S. A., Henriksen, P., Vogt, J. K., Hansen, T. H., Ahonen, L., Suvitaival, T., Hein Zobel, E., Frimodt-Møller, M., Hansen, T. W., Hansen, T., Parving, H-H., Legido-Quigley, C., Rossing, P. & Pedersen, O., Dec 2020, In: Diabetologia. 63, 12, p. 2713-2724 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Neuroprotective effects of oxyresveratrol on 6-hydroxydopamine on medial forebrain bundles in a rat model of Parkinson disease: abridged secondary publication

Shah, A., Ho, Y. S., Ng, K. M., Wang, M., Legido-Quigley, C. & Chang, R. C. C., Dec 2020, In: Hong Kong medical journal = Xianggang yi xue za zhi. 26 Suppl 7, 6, p. 26-28 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Circulating Metabolites and Lipids Are Associated to Diabetic Retinopathy in Individuals With Type 1 Diabetes

Curovic, V. R., Suvitaival, T., Mattila, I., Ahonen, L., Trošt, K., Theilade, S., Hansen, T. W., Legido-Quigley, C. & Rossing, P., Oct 2020, In: Diabetes. 69, 10, p. 2217-2226 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Integrated lipidomics and proteomics network analysis highlights lipid and immunity pathways associated with Alzheimer's disease

Xu, J., Bankov, G., Kim, M., Wretlind, A., Lord, J., Green, R., Hodges, A., Hye, A., Aarsland, D., Velayudhan, L., Dobson, R. J. B., Proitsi, P., Legido-Quigley, C. & AddNeuroMed Consortium, 21 Sep 2020, In: Translational Neurodegeneration. 9, 1, p. 36 36.

Research output: Contribution to journal › Journal article › Research › peer-review

Major decreases in the lipidome following liraglutide treatment: 21-25 September 2020.

Wretlind, A., Zobel, E. H., Ripa, R. S., Von Scholten, B. J., Suvitaival, T., Hansen, T. W., Vestergaard, H., Kjær, A., Legido-Quigley, C. & Rossing, P., 25 Aug 2020, In: Diabetologia. 63, Suppl 1, p. S252 525.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Metabolites of the mitochondrial energy production are associated with future cardiovascular morbidity and mortality in type 1 diabetes

Tofte, N., Suvitaival, T., Trošt, K., Mattila, I., Theilade, S., Winther, S. A., Frimodt-Møller, M., Legido-Quigley, C. & Rossing, P., 25 Aug 2020, In: Diabetologia. 63, Suppl 1, p. S447 940.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Profiling of gut microbiota and plasma metabolites in persons with type 1 diabetes and kidney disease

Henriksen, P., Winther, S. A., Vogt, J. K., Hansen, T. H., Ahonen, L. L., Suvitaival, T., Frimodt-Møller, M., Hansen, T. W., Hansen, T., Parving, H-H. D., Legido-Quigley, C., Rossing, P. & Pedersen, O., 25 Aug 2020, In: Diabetologia. 63, Suppl 1, p. S384 795.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

The circulating lipidome in diabetic retinopathy

Suvitaival, T., Curovic, V. R., Ahonen, L. L., Theilade, S., Hansen, T. W., Legido-Quigley, C. & Rossing, P., 25 Aug 2020, In: Diabetologia. 63, Suppl 1, p. S395 820.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Lipidomics of human adipose tissue reveals diversity between body areas

Al-Sari, N., Suvitaival, T., Mattila, I., Ali, A., Ahonen, L., Trost, K., Henriksen, T. F., Pociot, F., Dragsted, L. O. & Legido-Quigley, C., 16 Jun 2020, In: PLoS One. 15, 6, p. e0228521 e0228521.

Research output: Contribution to journal › Journal article › Research › peer-review

Deregulation of the Purine Pathway in Pre-Transplant Liver Biopsies Is Associated with Graft Function and Survival after Transplantation

Xu, J., Hassan-Ally, M., Casas-Ferreira, A. M., Suvitaival, T., Ma, Y., Vilca-Melendez, H., Rela, M., Heaton, N., Wayel, J. & Legido-Quigley, C., 5 Mar 2020, In: Journal of Clinical Medicine. 9, 3, 117.

Research output: Contribution to journal › Journal article › Research › peer-review

Blood Metabolite Signatures of Metabolic Syndrome in Two Cross-Cultural Older Adult Cohorts

Mahajan, U. V., Varma, V. R., Huang, C-W., An, Y., Tanaka, T., Ferrucci, L., Takebayashi, T., Harada, S., Iida, M., Legido-Quigley, C. & Thambisetty, M., 16 Feb 2020, In: International Journal of Molecular Sciences. 21, 4, 1324.

Research output: Contribution to journal › Journal article › Research › peer-review

Lipidomic profiles, lipid trajectories and clinical biomarkers in female elite endurance athletes

Varga, T. V., Ali, A., Herrera, J. A. R., Ahonen, L. L., Mattila, I. M., Al-Sari, N. H., Legido-Quigley, C., Skouby, S., Brunak, S. & Tornberg, Å. B., 11 Feb 2020, In: Scientific Reports. 10, 1, 2349.

Research output: Contribution to journal › Journal article › Research › peer-review

Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study

Mahajan, U. V., Varma, V. R., Griswold, M. E., Blackshear, C. T., An, Y., Oommen, A. M., Varma, S., Troncoso, J. C., Pletnikova, O., O'Brien, R., Hohman, T. J., Legido-Quigley, C. & Thambisetty, M., 24 Jan 2020, In: PLOS Medicine. 17, 1, e1003012.

Research output: Contribution to journal › Journal article › Research › peer-review

Describing the fecal metabolome in cryogenically collected samples from healthy participants

Trošt, K., Ahonen, L., Suvitaival, T., Christiansen, N., Nielsen, T., Thiele, M., Jacobsen, S., Krag, A., Rossing, P., Hansen, T., Dragsted, L. O. & Legido-Quigley, C., 21 Jan 2020, In: Scientific Reports. 10, 1, 885.

Research output: Contribution to journal › Journal article › Research › peer-review

Dickkopf-1 overexpression in vitro nominates candidate blood biomarkers relating to Alzheimer's Disease pathology

Shi, L., Winchester, L. M., Liu, B. Y., Killick, R., Ribe, E. M., Westwood, S., Baird, A. L., Buckley, N. J., Hong, S., Dobricic, V., Kilpert, F., Franke, A., Kiddle, S., Sattlecker, M., Dobson, R., Cuadrado, A., Hye, A., Ashton, N. J., Morgan, A. R., Bos, I., Vos, S. J. B., Ten Kate, M., Scheltens, P., Vandenberghe, R., Gabel, S., Meersmans, K., Engelborghs, S., De Roeck, E. E., Sleegers, K., Frisoni, G. B., Blin, O., Richardson, J. C., Bordet, R., Molinuevo, J. L., Rami, L., Wallin, A., Kettunen, P., Tsolaki, M., Verhey, F., Lleó, A., Alcolea, D., Popp, J., Peyratout, G., Martinez-Lage, P., Tainta, M., Johannsen, P., Teunissen, C. E., Freund-Levi, Y., Frölich, L., Legido-Quigley, C., Barkhof, F., Blennow, K., Rasmussen, K. L., Nordestgaard, B. G., Frikke-Schmidt, R., Nielsen, S. F., Soininen, H., Vellas, B., Kloszewska, I., Mecocci, P., Zetterberg, H., Morgan, B. P., Streffer, J., Visser, P. J., Bertram, L., Nevado-Holgado, A. J. & Lovestone, S., 2020, In: Journal of Alzheimer's Disease. 77, 3, p. 1353-1368 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort

Westwood, S., Baird, A. L., Anand, S. N., Nevado-Holgado, A. J., Kormilitzin, A., Shi, L., Hye, A., Ashton, N. J., Morgan, A. R., Bos, I., Vos, S. J. B., Baker, S., Buckley, N. J., Ten Kate, M., Scheltens, P., Teunissen, C. E., Vandenberghe, R., Gabel, S., Meersmans, K., Engelborghs, S., De Roeck, E. E., Sleegers, K., Frisoni, G. B., Blin, O., Richardson, J. C., Bordet, R., Molinuevo, J. L., Rami, L., Wallin, A., Kettunen, P., Tsolaki, M., Verhey, F., Lléo, A., Sala, I., Popp, J., Peyratout, G., Martinez-Lage, P., Tainta, M., Johannsen, P., Freund-Levi, Y., Frölich, L., Dobricic, V., Legido-Quigley, C., Bertram, L., Barkhof, F., Zetterberg, H., Morgan, B. P., Streffer, J., Visser, P. J. & Lovestone, S., 2020, In: Journal of Alzheimer's Disease. 74, 1, p. 213-225 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort

Stamate, D., Kim, M., Proitsi, P., Westwood, S., Baird, A., Nevado-Holgado, A., Hye, A., Bos, I., Vos, S. J. B., Vandenberghe, R., Teunissen, C. E., Kate, M. T., Scheltens, P., Gabel, S., Meersmans, K., Blin, O., Richardson, J., De Roeck, E., Engelborghs, S., Sleegers, K., Bordet, R., Ramit, L., Kettunen, P., Tsolaki, M., Verhey, F., Alcolea, D., Lléo, A., Peyratout, G., Tainta, M., Johannsen, P., Freund-Levi, Y., Frölich, L., Dobricic, V., Frisoni, G. B., Molinuevo, J. L., Wallin, A., Popp, J., Martinez-Lage, P., Bertram, L., Blennow, K., Zetterberg, H., Streffer, J., Visser, P. J., Lovestone, S. & Legido-Quigley, C., Dec 2019, In: Alzheimer's & dementia (New York, N. Y.). 5, p. 933-938 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Metabolomic assessment reveals alteration in polyols and branched chain amino acids associated with present and future renal impairment in a discovery cohort of 637 persons with type 1 diabetes

Tofte, N., Suvitaival, T., Trošt, K., Mattila, I., Theilade, S., Winther, S. A., Ahluwalia, T. S., Frimodt-Møller, M., Legido-Quigley, C. & Rossing, P., 22 Nov 2019, In: Frontiers in Endocrinology. 10, p. 1-11 11 p., 818.

Research output: Contribution to journal › Journal article › Research › peer-review

Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay

Shi, L., Westwood, S., Baird, A. L., Winchester, L., Dobricic, V., Kilpert, F., Hong, S., Franke, A., Hye, A., Ashton, N. J., Morgan, A. R., Bos, I., Vos, S. J. B., Buckley, N. J., Kate, M. T., Scheltens, P., Vandenberghe, R., Gabel, S., Meersmans, K., Engelborghs, S., De Roeck, E. E., Sleegers, K., Frisoni, G. B., Blin, O., Richardson, J. C., Bordet, R., Molinuevo, J. L., Rami, L., Wallin, A., Kettunen, P., Tsolaki, M., Verhey, F., Lleó, A., Alcolea, D., Popp, J., Peyratout, G., Martinez-Lage, P., Tainta, M., Johannsen, P., Teunissen, C. E., Freund-Levi, Y., Frölich, L., Legido-Quigley, C., Barkhof, F., Blennow, K., Zetterberg, H., Baker, S., Morgan, B. P., Streffer, J., Visser, P. J., Bertram, L., Lovestone, S. & Nevado-Holgado, A. J., Nov 2019, In: Alzheimer's & dementia : the journal of the Alzheimer's Association. 15, 11, p. 1478-1488 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Abstracts

Bastrup Israelsen, M., Trošt, K., Stæhr Madsen, B., Suvitaival, T., Hansen, C., Thiele, M., Rossing, P., Hansen, T., Legido-Quigley, C. & Krag, A., Oct 2019, In: Hepatology. 70, Suppl 1, p. 172-173 1 p., 267.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Polyols and Branched Chained Amino Acids Are Associated with Present and Future Renal Impairment in Type 1 Diabetes

Tofte, N., Suvitaival, T., Trošt, K., Mattila, I., Theilade, S., Winther, S. A., Ahluwalia, T. S., Frimodt-Møller, M., Legido-Quigley, C. & Rossing, P., Oct 2019, In: Journal of the American Society of Nephrology. 30, p. 362 1 p., TH-PO934.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

High sensitivity LC-MS profiling of antibody-drug conjugates with difluoroacetic acid ion pairing

Nguyen, J. M., Smith, J., Rzewuski, S., Legido-Quigley, C. & Lauber, M. A., 10 Sep 2019, In: mAbs. 11, 8, p. 1358-1366 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cell populations and molecular biomarkers in blood and urine characterise nephropathy in type 1 diabetes

Henriksen, P., Kyluik-Price, D., Winther, S. A., Suvitaival, T., Legido-Quigley, C., Timmermann, D. B. & Rossing, P., 1 Sep 2019, In: Diabetologia. 62, Suppl 1, p. 478 1 p., 986.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

55 ^th EASD Annual Meeting of the European Association for the Study of Diabetes

Al-Sari, N. H., Schmidt, S., Suvitaival, T., Kim, M., Trošt, K., Ranjan, A., Christensen, M., Overgaard, A. J., Pociot, F., Nørgaard, K. & Legido-Quigley, C., Sep 2019, In: Diabetologia. 62, Suppl 1, p. 1-600 600 p., 669.

Research output: Contribution to journal › Comment/debate › Research › peer-review

Circulating metabolites are associated with present and future renal impairment in type 1 Diabetes

Tofte, N., Suvitaival, T., Trošt, K., Mattila, I., Theilade, S., Winther, S. A., Ahluwalia, T. S., Frimodt-Møller, M., Legido-Quigley, C. & Rossing, P., Sep 2019, In: Diabetologia. 62, Suppl 1, p. 30 1 p., 57.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Renal function dominates the landscape of the metabolome in type 1 diabetes

Suvitaival, T., Tofte, N., Mattila, I., Trošt, K., Theilade, S., Winther, S. A., Ahluwalia, T. S., Frimodt-Møller, M., Rossing, P. & Legido-Quigley, C., Sep 2019, In: Diabetologia. 62, Suppl 1, p. 455 1 p., 936.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort

Kim, M., Snowden, S., Suvitaival, T., Ali, A., Merkler, D. J., Ahmad, T., Westwood, S., Baird, A., Proitsi, P., Nevado-Holgado, A., Hye, A., Bos, I., Vos, S., Vandenberghe, R., Teunissen, C., Ten Kate, M., Scheltens, P., Gabel, S., Meersmans, K., Blin, O., Richardson, J., De Roeck, E., Sleegers, K., Bordet, R., Rami, L., Kettunen, P., Tsolaki, M., Verhey, F., Sala, I., Lléo, A., Peyratout, G., Tainta, M., Johannsen, P., Freund-Levi, Y., Frölich, L., Dobricic, V., Engelborghs, S., Frisoni, G. B., Molinuevo, J. L., Wallin, A., Popp, J., Martinez-Lage, P., Bertram, L., Barkhof, F., Ashton, N., Blennow, K., Zetterberg, H., Streffer, J., Visser, P. J., Lovestone, S. & Legido-Quigley, C., Jun 2019, In: Alzheimer's & dementia : the journal of the Alzheimer's Association. 15, 6, p. 817-827 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Oxyresveratrol exerts ATF4- and Grp78-mediated neuroprotection against endoplasmic reticulum stress in experimental Parkinson's disease

Shah, A., Chao, J., Legido-Quigley, C. & Chang, R. C-C., 17 May 2019, (E-pub ahead of print) In: Nutritional Neuroscience. p. 1-16 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum

Bos, I., Vos, S., Verhey, F., Scheltens, P., Teunissen, C., Engelborghs, S., Sleegers, K., Frisoni, G., Blin, O., Richardson, J. C., Bordet, R., Tsolaki, M., Popp, J., Peyratout, G., Martinez-Lage, P., Tainta, M., Lleó, A., Johannsen, P., Freund-Levi, Y., Frölich, L., Vandenberghe, R., Westwood, S., Dobricic, V., Barkhof, F., Legido-Quigley, C., Bertram, L., Lovestone, S., Streffer, J., Andreasson, U., Blennow, K., Zetterberg, H. & Visser, P. J., 1 May 2019, In: Alzheimer's & dementia : the journal of the Alzheimer's Association. 15, 5, p. 644-654 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Palmitate and Stearate are Increased in the Plasma in a 6-OHDA Model of Parkinson's Disease

Shah, A., Han, P., Wong, M-Y., Chang, R. C-C. & Legido-Quigley, C., 13 Feb 2019, In: Metabolites. 9, 2, 31.

Research output: Contribution to journal › Journal article › Research › peer-review

PLASMA PRIMARY FATTY AMIDES ASSOCIATE TO CSF AMYLOID LEVELS AND ALZHEIMER’S DISEASE PROGRESSION IN THE EMIF-AD BIOMARKER DISCOVERY COHORT

Kim, M., Snowden, S. G., Ahmad, T., Westwood, S., Baird, A., Proitsi, P., Nevado-Holgado, A., Hye, A., Ashton, N. J., Bos, I., Vos, S. J. B., Vandenberghe, R., Scheltens, P., Engelborghs, S., Frisoni, G. B., Molinuevo, J. L., Wallin, A., Lleo, A., Popp, J., Martinez-Lage, P., Bertram, L., Barkhof, F., Zetterberg, H., Streffer, J., Visser, P. J., Lovestone, S. & Legido-Quigley, C., 1 Jul 2018, In: Alzheimer's & Dementia. 14, 7, p. 1161-1161 1 p.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Metabolomics reveals immunomodulation as a possible mechanism for the antibiotic effect of (Buch.-Ham. ex D. Don) H.Gross

Han, P., Huang, Y., Xie, Y., Yang, W., Xiang, W., Hylands, P. J. & Legido-Quigley, C., Jul 2018, In: Metabolomics. 14, 7, p. 91

Research output: Contribution to journal › Journal article › Research › peer-review

Small molecule biomarkers in Alzheimer’s disease

Kim, M. & Legido-Quigley, C., 4 May 2018, In: Oils and Oilseeds Journal. 25, 4, 22 p., D404.

Research output: Contribution to journal › Review › Research › peer-review