Claus Flensted Behrens

2024

Impact of geometric correction on echo-planar imaging-based apparent diffusion coefficient maps for abdominal radiotherapy

Winther Hasler, S., Bernchou, U., Behrens, C. P., Vogelius, I. R., Bisgaard, A. L. H., Jokivuolle, M., Bertelsen, A., Schytte, T., Brink, C. & Mahmood, F., 30 Aug 2024, (E-pub ahead of print) In: Biomedical physics & engineering express.

Research output: Contribution to journal › Journal article › Research › peer-review

MR-guided stereotactic radiotherapy of infra-diaphragmatic oligometastases: Evaluation of toxicity and dosimetric parameters

van Overeem Felter, M., Krause Møller, P., Josipovic, M., Nørring Bekke, S., Bernchou, U., Serup-Hansen, E., Madsen, K., Parikh, P., Kim, J., Geertsen, P., Behrens, C. P., Vogelius, I. R., Pøhl, M., Schytte, T. & Fredberg Persson, G., 2024, In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 192, p. 1-6 6 p., 110090.

Research output: Contribution to journal › Journal article › Research › peer-review

Nivolumab With or Without Ipilimumab Combined with Stereotactic Body Radiotherapy in patients with Metastatic Biliary Tract Cancer: A Randomized Phase 2 Study

Markussen, A., Johansen, J. S., Larsen, F. O., Theile, S., Hasselby, J. P., Willemoe, G. L., Lorentzen, T., Madsen, K., Høgdall, E., Poulsen, T. S., Wilken, E. E., Geertsen, P., Behrens, C. P., Svane, I. M., Nielsen, D. & Chen, I. M., 15 Aug 2024, In: Clinical Cancer Research. 30, 16, p. 3428-3437 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Roar-a: re-optimization based Online Adaptive Radiotherapy of anal cancer, a prospective phase II trial protocol

Storm, K. S., Åström, L. M., Sibolt, P., Behrens, C. P., Persson, G. F. & Serup-Hansen, E., 25 Mar 2024, In: BMC Cancer. 24, 1, p. 374 374.

Research output: Contribution to journal › Journal article › Research › peer-review

2023

Accumulated dose implications from systematic dose-rate transients in gated treatments with Viewray MRIdian accelerators

Klavsen, M. F. F., Ankjærgaard, C., Boye, K., Behrens, C. P., Vogelius, I. R., Ehrbar, S., Baumgartl, M., Rippke, C., Buchele, C., Renkamp, K., Santurio, G. V. & Andersen, C. E., 8 Sept 2023, In: Biomedical physics & engineering express. 9, 6, 065001.

Research output: Contribution to journal › Journal article › Research › peer-review

Interfractional Dose Accumulation for MR-guided Liver SBRT: Variation Among Algorithms is Highly Patient- and Fraction-dependent

Wahlstedt, I., George Smith, A., Andersen, C. E., Behrens, C. P., Nørring Bekke, S., Boye, K., van Overeem Felter, M., Josipovic, M., Petersen, J., Lenora Risumlund, S., Tascón-Vidarte, J. D., van Timmeren, J. E. & Vogelius, I. R., May 2023, In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 182, 109448.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Interim analysis of patient-reported outcome compliance and dosimetry in a phase 3 randomized clinical trial of oesophagus-sparing spinal radiotherapy

Nielsen, A. M., Storm, K. S., Laursen, M. R. T., Gram, V. R., Rechner, L. A., Ottosson, W., Suppli, M. H., Sibolt, P., Behrens, C. F., Vogelius, I. R. & Persson, G. F., 2023, In: Acta Oncologica. 62, 11, p. 1496-1501 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2022

Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer

Johansen, A. Z., Carretta, M., Thorseth, M.-L., Khan, S., Fjæstad, K. Y., Brøchner, C. B., Linder, H., Ankjærgaard, C., Donia, M., Chen, I., Nielsen, D. L., Behrens, C. P. & Madsen, D. H., 12 May 2022, In: Pharmaceutics. 14, 5, 1046.

Research output: Contribution to journal › Journal article › Research › peer-review

Evaluation of an automated template-based treatment planning system for radiotherapy of anal, rectal and prostate cancer

Calmels, L., Sibolt, P., Åström, L. M., Serup-Hansen, E., Lindberg, H., Fromm, A. L., Persson, G., Sjöström, D., Geertsen, P. & Behrens, C. P., Jun 2022, In: Technical Innovations and Patient Support in Radiation Oncology. 22, p. 30-36 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

Gating has a negligible impact on dose delivered in MRI-guided online adaptive radiotherapy of prostate cancer

Wahlstedt, I., Andratschke, N., Behrens, C. P., Ehrbar, S., Gabryś, H. S., Schüler, H. G., Guckenberger, M., Smith, A. G., Tanadini-Lang, S., Tascón-Vidarte, J. D., Vogelius, I. R. & van Timmeren, J. E., May 2022, In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 170, p. 205-212 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Online adaptive radiotherapy of anal cancer: Normal tissue sparing, target propagation methods, and first clinical experience

Åström, L. M., Behrens, C. P., Storm, K. S., Sibolt, P. & Serup-Hansen, E., Nov 2022, In: Radiotherapy and Oncology. 176, p. 92-98 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

Online adaptive radiotherapy of urinary bladder cancer with full re-optimization to the anatomy of the day: Initial experience and dosimetric benefits

Åström, L. M., Behrens, C. P., Calmels, L., Sjöström, D., Geertsen, P., Mouritsen, L. S., Serup-Hansen, E., Lindberg, H. & Sibolt, P., Jun 2022, In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 171, p. 37-42 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Randomized Phase II Study of Nivolumab With or Without Ipilimumab Combined With Stereotactic Body Radiotherapy for Refractory Metastatic Pancreatic Cancer (CheckPAC)

Chen, I. M., Johansen, J. S., Theile, S., Hjaltelin, J. X., Novitski, S. I., Brunak, S., Hasselby, J. P., Willemoe, G. L., Lorentzen, T., Madsen, K., Jensen, B. V., Wilken, E. E., Geertsen, P., Behrens, C., Nolsoe, C., Hermann, K. L., Svane, I. M. & Nielsen, D., 20 Sept 2022, In: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40, 27, p. 3180-3189 10 p., JCO.21.02511.

Research output: Contribution to journal › Journal article › Research › peer-review

Robust extraction of biological information from diffusion-weighted magnetic resonance imaging during radiotherapy using semi-automatic delineation

Bisgaard, A. L. H., Brink, C., Fransen, M. L., Schytte, T., Behrens, C. P., Vogelius, I., Nissen, H. D. & Mahmood, F., Jan 2022, In: Physics and imaging in radiation oncology. 21, p. 146-152 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Single-isocenter stereotactic non-coplanar arc treatment of 200 patients with brain metastases: multileaf collimator size and setup uncertainties

Calmels, L., Blak Nyrup Biancardo, S., Sibolt, P., Nørring Bekke, S., Bjelkengren, U., Wilken, E., Geertsen, P., Sjöström, D. & Behrens, C. F., May 2022, In: Strahlentherapie und Onkologie. 198, 5, p. 436-447 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Time-resolved plastic scintillator dosimetry in MR linear accelerators without image distortion

Klavsen, M. F., Ankjærgaard, C., Behrens, C. P., Vogelius, I. R., Boye, K., Hansen, R. H. & Andersen, C. E., Jun 2022, In: Radiation Measurements. 154, 106759.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

2021

Clinical implementation of artificial intelligence-driven cone-beam computed tomography-guided online adaptive radiotherapy in the pelvic region

Sibolt, P., Andersson, L. M., Calmels, L., Sjöström, D., Bjelkengren, U., Geertsen, P. & Behrens, C. F., Jan 2021, In: Physics and imaging in radiation oncology. 17, p. 1-7 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Irradiation of subcutaneous mouse tumors with a clinical linear accelerator validated by alanine dosimetry

Ankjærgaard, C., Johansen, A. Z., von Staffeldt, M. M. K., Andersen, C. E., Madsen, D. H. & Behrens, C. F., Sept 2021, In: Radiation Measurements. 147, 106636.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Simulated Cone-Beam Computed Tomography Based Online Adaptive Radiotherapy of Anal Cancer - Potential Dosimetric Benefit

Andersson, L., Behrens, C. F., Serup-Hansen, E. & Sibolt, P., 1 Nov 2021, In: International journal of radiation oncology, biology, physics. 111, 3, p. e509-e510

Research output: Contribution to journal › Journal article › Research › peer-review

2020

Analysis of early respiratory-related mortality after radiation therapy of non-small-cell lung cancer: feasibility of automatic data extraction for dose-response studies

Stervik, L., Pettersson, N., Scherman, J., Behrens, C. F., Ceberg, C., Engelholm, S., Gunnarsson, K., Hallqvist, A., Nyman, J., Persson, G. F., Pøhl, M., Wahlstedt, I., Vogelius, I. R. & Bäck, A., Jun 2020, In: Acta Oncologica. 59, 6, p. 628-635 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

2019

Surface guided radiotherapy (SGRT) improves breast cancer patient setup accuracy

Kügele, M., Mannerberg, A., Nørring Bekke, S., Alkner, S., Berg, L., Mahmood, F., Thornberg, C., Edvardsson, A., Bäck, S. Å. J., Behrens, C. F. & Ceberg, S., Sept 2019, In: Journal of Applied Clinical Medical Physics. 20, 9, p. 61-68 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2017

Towards ultrasound-guided adaptive radiotherapy for cervical cancer: Evaluation of Elekta's semiautomated uterine segmentation method on 3D ultrasound images

Mason, S. A., O'Shea, T. P., White, I. M., Lalondrelle, S., Downey, K., Baker, M., Behrens, C. F., Bamber, J. C. & Harris, E. J., Jul 2017, In: Medical Physics. 44, 7, p. 3630-3638 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2016

Determining intrafractional prostate motion using four dimensional ultrasound system

Baker, M. & Behrens, C. F., 15 Jul 2016, In: B M C Cancer. 16, p. 484

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

Evaluation of uterine ultrasound imaging in cervical radiotherapy; a comparison of autoscan and conventional probe

Baker, M., Cooper, D. T. & Behrens, C. F., Oct 2016, In: The British journal of radiology. 89, 1066, p. 20160510

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

The advantage of deep-inspiration breath-hold and cone-beam CT based soft-tissue registration for locally advanced lung cancer radiotherapy

Ottosson, K. W., Rahma, F., Sjöström, D., Behrens, C. F. & Sibolt, P., Jun 2016, In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 119, 3, p. 432-7 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

2015

Adaptation requirements due to anatomical changes in free-breathing and deep-inspiration breath-hold for standard and dose-escalated radiotherapy of lung cancer patients

Sibolt, P., Ottosson, K. W., Sjöström, D., Larsen, C. & Behrens, C. F., Oct 2015, In: Acta oncologica . 54, 9, p. 1453-60 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Comment on "Characterization of the Exradin W1 scintillator for use in radiotherapy" [Med. Phys. 42, 297-304 (2015)]

Beierholm, A. R., Behrens, C. F. & Andersen, C. E., Jul 2015, In: Medical Physics. 42, 7, p. 4414-6 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Dose verification of radiotherapy for lung cancer by using plastic scintillator dosimetry and a heterogeneous phantom

Ottosson, W., Behrens, C. F. & E. Andersen, C., 2015, In: Journal of Physics: Conference Series (Online). 573, No. 1, 012022.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Measurements of the relative backscatter contribution to the monitor chamber for modern medical linear accelerators; a multi-center study

Sibolt , P., Cronholm , R. O., R. Beierholm , A. & Behrens, C. F., 2015, In: Radiation Measurements. 72, January, p. 75-80 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Monte Carlo calculations support organ sparing in Deep-Inspiration Breath-Hold intensity-modulated radiotherapy for locally advanced lung cancer

Ottosson, K. W., Sibolt, P., Larsen, C., Andersen, J. A. L., Borissova, S., Mellemgaard, A. & Behrens, C. F., Oct 2015, In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 117, 1, p. 55-63 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Prostate displacement during transabdominal ultrasound image-guided radiotherapy assessed by real-time four-dimensional transperineal monitoring

Baker, M. & Behrens, C. F., Oct 2015, In: Acta oncologica . 54, 9, p. 1508-14 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

RADIATION PROTECTION OF LINAC BUNKERS. A USER-FRIENDLY APPROACH

Holten Sørensen, T., Olsen, K. J. & Behrens, C. F., 2015, In: Radiation Protection Dosimetry. 65, 1-4, p. 503-505

Research output: Contribution to journal › Journal article › Research › peer-review

2014

Deformable image registration for geometrical evaluation of DIBH radiotherapy treatment of lung cancer patients

Ottosson, K. W., Andersen, J. A. L., Borrisova, S., Mellemgaard, A. & Behrens, C. F., 2014, In: Journal of Physics: Conference Series (Online). 489, 012077.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Determining inter-fractional motion of the uterus using 3D ultrasound imaging during radiotherapy for cervical cancer

Baker, M., Jensen, J. A. & Behrens, C. F., 2014, In: Spie Proceedings. 9040, 90400Y.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Dosimetric and geometric evaluation of the use of deformable image registration in adaptive intensity-modulated radiotherapy for head-and-neck cancer

Eiland, R. B., Maare, C., Sjöström, D., Samsøe, E. & Behrens, C. F., Sept 2014, In: Journal of Radiation Research. 55, 5, p. 1002-8 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Dosimetric characterization of the Exradin W1 plastic scintillator detector through comparison with an in-house developed scintillator system. / Beierholm, Anders Ravnsborg

Beierholm, A. R., Behrens, C. F. & Andersen, C. E., 2014, In: Radiation Measurements. 69, p. 50-56 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of ultrasound probe pressure on uterine positional displacement in gynecologic cancer patients

Baker, M., Juhler-Nøttrup, T. & Behrens, C. F., Nov 2014, In: Women's health (London, England). 10, 6, p. 583-90 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Optical surface scanning for respiratory motion monitoring in radiotherapy: a feasibility study

Bekke, S. L., Mahmood, F., Helt-Hansen, J. & Behrens, C. F., 2014, In: Spie Proceedings. 9036, 90360I.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

2013

Acquiring beam data for a flattening-filter free linear accelerator using organic scintillators

Behrens, C. F., 2013, In: Radiation Measurements. 56, September, p. 290-93 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Quantitative image quality evaluation of pelvic computed tomography-based imaging systems: a novel concept in radiotherapy

Behrens, C. F., Andreasen, T. B., Lindberg, H., Buhl, S. K., Vestergaard, A. S., Elstrøm, U. V. & Sjöström, D., Oct 2013, In: Acta oncologica . 52, 7, p. 1579-82 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

3 Citations (Scopus)

Variability in prostate and seminal vesicle delineations defined on magnetic resonance images, a multi-observer, -center and -sequence study

Nyholm, T., Jonsson, J., Söderström, K., Bergström, P., Carlberg, A., Frykholm, G., Behrens, C. F., Geertsen, P. F., Trepiakas, R., Hanvey, S., Sadozye, A., Ansari, J., McCallum, H., Frew, J., McMenemin, R. & Zackrisson, B., 24 May 2013, In: Radiation Oncology. 8, 1, p. 126

Research output: Contribution to journal › Journal article › Research › peer-review

40 Citations (Scopus)

2012

Introducing multiple treatment plan-based comparison to investigate the performance of gantry angle optimisation (GAO) in IMRT for head and neck cancer

Thor, M., Benedek, H., Knöös, T., Engström, P., Behrens, C. F., Hauer, A. K., Sjöström, D. & Ceberg, C., 2012, In: Acta Oncologica. 51, 6, p. 743-51 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

Volume dose ratios relevant for alanine dosimetry in small, 6 MV photon beams

Cronholm, R. O. & Behrens, C. F., 2012, In: Radiation Measurements. 47, 10, p. 1014-1017 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

2011

Characterizing a pulse-resolved dosimetry system for complex radiotherapy beams using organic scintillators

Beierholm, A. R., Ottosson, R. O., Lindvold, L. R., Behrens, C. F. & Andersen, C., 2011, In: Physics in Medicine and Biology. 56, 10, p. 3033-45 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

37 Citations (Scopus)

CTC-ask: a new algorithm for conversion of CT numbers to tissue parameters for Monte Carlo dose calculations applying DICOM RS knowledge

Ottosson, R. O. & Behrens, C. F., 2011, In: Physics in Medicine and Biology. 56, 22, p. N263-74

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Implementing RapidArc into clinical routine: a comprehensive program from machine QA to TPS validation and patient QA

Van Esch, A., Huyskens, D. P., Behrens, C. F., Samsøe, E., Sjölin, M., Bjelkengren, U., Sjöström, D. P. F., Clermont, C., Hambach, L. & Sergent, F., 2011, In: Medical Physics. 38, 9, p. 5146-66 21 p.

Research output: Contribution to journal › Journal article › Research › peer-review

72 Citations (Scopus)

2010

Pareto front analysis of 6 and 15 MV dynamic IMRT for lung cancer using pencil beam, AAA and Monte Carlo

Ottosson, R. O., Hauer, A. K. & Behrens, C. F., 2010, In: Physics in Medicine and Biology. 55, 16, p. 4521-4533 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

Claus Flensted Behrens

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