Personal profile
Expertises
M.D. PhD., and current postdoc. at Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre.
Main research areas
Hepatitis C, liver fibrosis, Direct Acting Antivirals, viral resistance, Covid-19, immunology.
Current research
Covid-19 and immunology. Durability of neutralizing antibodies in patients hospitalized, non-hospitalized and vaccinated individuals.
Liver fibrosis in patients treated with DAA and who achieve cure. Changes in liver parameters after cure, patients are followed for 4 years.
Hepatitis C and immunology. Changes in the immunesystem after cure vs. treatment failure.
Nationwide clinical study that investigates patients with DAA treatment failure for development of viral resistance.
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Collaborations and top research areas from the last five years
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Cure of chronic hepatitis C virus infection after DAA treatment only partially restores the functional capacity of exhausted T cell subsets: a systematic review
Apol, Á. D., Sølund, C., Vinten, C., Underwood, A. P., Bukh, J. & Weis, N., 2025, In: Frontiers in Immunology. 16, 1546915.Research output: Contribution to journal › Review › peer-review
3 Citations (Scopus) -
T cell receptor usage and epitope specificity amongst CD8+ and CD4+ SARS-CoV-2-specific T cells
Fahnøe, U., Feng, S., Underwood, A. P., Jacobsen, K., Ameri, A., Blicher, T. H., Sølund, C. S., Rosenberg, B. R., Brix, L., Weis, N. & Bukh, J., 28 Feb 2025, In: Frontiers in Immunology. 16, 18 p., 1510436.Research output: Contribution to journal › Journal article › Research › peer-review
3 Citations (Scopus) -
An inactivated SARS-CoV-2 vaccine based on a Vero cell culture-adapted high-titer virus confers cross-protection in small animals
Offersgaard, A., Duarte Hernandez, C. R., Zhou, Y., Duan, Z., Gammeltoft, K. A., Hartmann, K. T., Fahnøe, U., Marichal-Gallardo, P., Alzua, G. P., Underwood, A. P., Sølund, C., Weis, N., Bonde, J. H., Christensen, J. P., Pedersen, G. K., Jensen, H. E., Holmbeck, K., Bukh, J. & Gottwein, J. M., 24 Jul 2024, In: Scientific Reports. 14, 1, p. 17039 17039.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
Effect of direct-acting antivirals on the titers of human pegivirus 1 during treatment of chronic hepatitis C patients
Fahnøe, U., Madsen, L. W., Christensen, P. B., Sølund, C. S., Mollerup, S., Pinholt, M., Weis, N., Øvrehus, A. & Bukh, J., 3 Sept 2024, In: Microbiology spectrum. 12, 9, p. e0064124Research output: Contribution to journal › Journal article › Research › peer-review
4 Citations (Scopus) -
Neutralisation Resistance of SARS-CoV-2 Spike-Variants is Primarily Mediated by Synergistic Receptor Binding Domain Substitutions
Pham, L. V., Underwood, A. P., Binderup, A., Fahnøe, U., Fernandez-Antunez, C., Lopez-Mendez, B., Ryberg, L. A., Galli, A., Sølund, C., Weis, N., Ramirez, S. & Bukh, J., Dec 2024, In: Emerging microbes & infections. 13, 1, p. 2412643 2412643.Research output: Contribution to journal › Journal article › Research › peer-review
5 Citations (Scopus)