Research output per year
Research output per year
Personal profile
Expertises
Lipid metabolism; apolipoprotein; atherosclerosis; sphingolipids
Main research areas
Our main research interest is lipoprotein metabolism and risk of cardiovascular disease and diabetes.
Current research
Our main area of interest is apolipoprotein M (apoM) and its ligand Sphingosine-1-phosphate (S1P). S1P is a small bioactive molecule with multiple effects on endothelial cells, angiogenesis and inflammation. We investigate the role of apoM/S1P axis on lipoprotein metabolism, endothelial cell functions, and its association with development of experimental diabetes and cardiovascular diseases.
Potential conflicts of interest
None
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Association between plasma apolipoprotein M and cardiac autonomic neuropathy in type 1 diabetes
Safi, M., Borup, A., Stevns Hansen, C., Rossing, P., Thorsten Jensen, M. & Christoffersen, C., Jul 2022, In: Diabetes Research and Clinical Practice. 189, 109943.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of apolipoprotein M and sphingosine-1-phosphate with brown adipose tissue after cold exposure in humans
Borup, A., Donkin, I., Boon, M. R., Frydland, M., Martinez-Tellez, B., Loft, A., Keller, S. H., Kjaer, A., Kjaergaard, J., Hassager, C., Barrès, R., Rensen, P. C. N. & Christoffersen, C., 5 Nov 2022, In: Scientific Reports. 12, 1, p. 18753 18753.Research output: Contribution to journal › Journal article › Research › peer-review
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Associations between Albuminuria, Estimated GFR and Cardiac Phenotype in a Cohort with Chronic Kidney Disease - The CPH-CKD ECHO Study
Landler, N. E., Olsen, F. J., Christensen, J., Bro, S., Feldt-Rasmussen, B., Hansen, D., Kamper, A-L., Christoffersen, C., Ballegaard, E. L. F., Sørensen, I. M. H., Bjergfelt, S. S., Seidelin, E., Gislason, G. & Biering-Sørensen, T., Nov 2022, In: Journal of Cardiac Failure. 28, 11, p. 1615-1627 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Coronary and extra-coronary artery calcium scores as predictors of cardiovascular events and mortality in chronic kidney disease stages 1-5: a prospective cohort study
Sørensen, I. M. H., Bjergfelt, S. S., Hjortkjær, H. Ø., Kofoed, K. F., Lange, T., Feldt-Rasmussen, B., Christoffersen, C. & Bro, S., 6 Sep 2022, (E-pub ahead of print) In: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. p. epubResearch output: Contribution to journal › Journal article › Research › peer-review
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Endothelial-specific loss of Sphingosine-1-Phosphate Receptor 1 increases vascular permeability and exacerbates Bleomycin-induced pulmonary fibrosis
Knipe, R. S., Spinney, J. J., Abe, E. A., Probst, C. K., Franklin, A., Logue, A., Giacona, F., Drummond, M., Griffith, J., Brazee, P. L., Hariri, L. P., Montesi, S. B., Black, K. E., Hla, T., Kuo, A., Cartier, A., Engelbrecht, E., Christoffersen, C., Shea, B. S., Tager, A. M., & 1 others, Jan 2022, In: American Journal of Respiratory Cell and Molecular Biology. 66, 1, p. 38-52 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
5 Citations (Scopus)