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  1. The Capital Region of Denmark
  2. Researchers
  3. Catharina Margrethe Lerche
  4. Publications
The Capital Region of Denmark - a part of Copenhagen University Hospital
Catharina Margrethe Lerche

Catharina Margrethe Lerche

M Sc Pharm, PhD

1 - 50 out of 55Page size: 50
  1. 2022
  2. Published

    Distribution of protoporphyrin IX in erythrocytes in a case of acquired erythropoietic protoporphyria

    Heerfordt, I. M., Fontenete, S., Lerche, C. M. & Wulf, H. C., Mar 2022, In: Photodiagnosis and Photodynamic Therapy. 37, 102629.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2021
  4. Published

    Anti-PD-1 Therapy with Adjuvant Ablative Fractional Laser Improves Anti-Tumor Response in Basal Cell Carcinomas

    Olesen, U. H., Wiinberg, M., Lerche, C. M., Jæhger, D. E., Andresen, T. L. & Haedersdal, M., 1 Dec 2021, In: Cancers. 13, 24, 6326.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Tumor Clearance and Immune Cell Recruitment in UV-Induced Murine Squamous Cell Carcinoma Exposed to Ablative Fractional Laser and Imiquimod Treatment

    Fontenete, S., Lerche, C. M., Paasch, U., Perez-Moreno, M., Olesen, U. H. & Haedersdal, M., Nov 2021, In: Lasers in Surgery and Medicine. 53, 9, p. 1227-1237 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Few X-ray and PUVA treatments accelerate photocarcinogenesis in hairless mice

    Lerche, C. M., Al-Chaer, R. N., Glud, M., Philipsen, P. A. & Wulf, H. C., Oct 2021, In: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. 20, 10, p. 1299-1307 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Keratinocyte Carcinoma and Photoprevention: The Protective Actions of Repurposed Pharmaceuticals, Phytochemicals and Vitamins

    Pihl, C., Togsverd-Bo, K., Andersen, F., Haedersdal, M., Bjerring, P. & Lerche, C. M., 22 Jul 2021, In: Cancers. 13, 15, 3684.

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    A Skin Cancer Prophylaxis Study in Hairless Mice Using Methylene Blue, Riboflavin, and Methyl Aminolevulinate as Photosensitizing Agents in Photodynamic Therapy

    Wulf, H. C., Al-Chaer, R. N., Glud, M., Philipsen, P. A. & Lerche, C. M., 5 May 2021, In: Pharmaceuticals (Basel, Switzerland). 14, 5, 433.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Bleomycin administered by laser-assisted drug delivery or intradermal needle-injection results in distinct biodistribution patterns in skin: in vivo investigations with mass spectrometry imaging

    Hendel, K., Hansen, A. C. N., Bik, L., Bagger, C., van Doorn, M. B. A., Janfelt, C., Olesen, U. H., Haedersdal, M. & Lerche, C. M., 1 Jan 2021, In: Drug Delivery . 28, 1, p. 1141-1149 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A Comparison of Human and Porcine Skin in Laser-Assisted Drug Delivery of Chemotherapeutics

    Rosenberg, L. K., Bagger, C., Janfelt, C., Haedersdal, M., Olesen, U. H. & Lerche, C. M., Jan 2021, In: Lasers in Surgery and Medicine. 53, 1, p. 162-170 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Efficacy and Safety of Laser-Assisted Combination Chemotherapy: An Explorative Imaging-Guided Treatment With 5-Fluorouracil and Cisplatin for Basal Cell Carcinoma

    Wenande, E., Hendel, K., Mogensen, M., Bagger, C., Mårtensson, N. L., Persson, D. P., Lerche, C. M., Husted, S., Janfelt, C., Togsverd-Bo, K., Anderson, R. R. & Haedersdal, M., Jan 2021, In: Lasers in Surgery and Medicine. 53, 1, p. 119-128 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. 2020
  13. Published

    Light-provoked skin symptoms on the hands of erythropoietic protoporphyria patients related to personal dosimeter measurements, skin symptoms, light protection and priming

    Heerfordt, I. M., Heydenreich, J., Philipsen, P. A., Lerche, C. M. & Wulf, H. C., Dec 2020, In: Journal of Photochemistry and Photobiology B: Biology. 213, p. 112054 112054.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Trends in erythrocyte protoporphyrin IX concentration by age, sex and season among patients with erythropoietic protoporphyria-20 years of follow-up

    Heerfordt, I. M., Lerche, C. M. & Wulf, H. C., Dec 2020, In: Photodiagnosis and Photodynamic Therapy. 32, p. 101928 101928.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Enhanced and Sustained Cutaneous Delivery of Vismodegib by Ablative Fractional Laser and Microemulsion Formulation

    Olesen, U. H., Clergeaud, G., Hendel, K. K., Yeung, K., Lerche, C. M., Andresen, T. L. & Haedersdal, M., Oct 2020, In: The Journal of investigative dermatology. 140, 10, p. 2051-2059 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2019
  17. Published

    Fractional laser-assisted topical delivery of bleomycin quantified by LC-MS and visualized by MALDI mass spectrometry imaging

    Hendel, K. K., Bagger, C., Olesen, U. H., Janfelt, C., Hansen, S. H., Haedersdal, M. & Lerche, C. M., Dec 2019, In: Drug Delivery . 26, 1, p. 244-251 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    A novel LC-MS/MS method to quantify eumelanin and pheomelanin and their relation to UVR sensitivity - A study on human skin biopsies

    Lerche, C. M., Olsen, P., Nissen, C. V., Philipsen, P. A. & Wulf, H. C., Nov 2019, In: Pigment Cell & Melanoma Research. 32, 6, p. 809-816 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Topical delivery of vismodegib using ablative fractional laser and micro-emulsion formulation in vitro

    Olesen, U. H., Clergeaud, G., Lerche, C. M., Andresen, T. L. & Haedersdal, M., Jan 2019, In: Lasers in Surgery and Medicine. 51, 1, p. 79-87 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. 2018
  21. Published

    Laser-assisted delivery enhances topical uptake of the anticancer agent cisplatin

    Wenande, E., Olesen, U. H., Boesen, M. R., Persson, D. P., Lerche, C. M., Stürup, S., Gammelgaard, B., Husted, S., Anderson, R. R. & Haedersdal, M., Nov 2018, In: Drug Delivery . 25, 1, p. 1877-1885 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2017
  23. Published

    Impact of UVR Exposure Pattern on Squamous Cell Carcinoma-A Dose-Delivery and Dose-Response Study in Pigmented Hairless Mice

    Lerche, C. M., Togsverd-Bo, K., Philipsen, P. A. & Wulf, H. C., 16 Dec 2017, In: International Journal of Molecular Sciences. 18, 12

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Red tattoos, ultraviolet radiation and skin cancer in mice

    Lerche, C. M., Heerfordt, I. M., Serup, J., Poulsen, T. & Wulf, H. C., Nov 2017, In: Experimental Dermatology. 26, 11, p. 1091-1096 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Skin reactions after photodynamic therapy are unaffected by 839 nm photobiomodulation therapy: A randomized, double-blind, placebo-controlled, clinical trial

    Bay, C., Vissing, A-C., Thaysen-Petersen, D., Lerche, C. M., Togsverd-Bo, K., Heydenreich, J. & Haedersdal, M., Nov 2017, In: Lasers in Surgery and Medicine. 49, 9, p. 810-818 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Comparison of Physical Pretreatment Regimens to Enhance Protoporphyrin IX Uptake in Photodynamic Therapy: A Randomized Clinical Trial

    Bay, C., Lerche, C. M., Ferrick, B., Philipsen, P. A., Togsverd-Bo, K. & Haedersdal, M., 1 Apr 2017, In: JAMA Dermatology. 153, 4, p. 270-278 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    UVR: sun, lamps, pigmentation and vitamin D

    Lerche, C. M., Philipsen, P. A. & Wulf, H. C., 16 Mar 2017, In: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. 16, 3, p. 291-301 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Search for Internal Cancers in Mice Tattooed with Inks of High Contents of Potential Carcinogens: A One-Year Autopsy Study of Red and Black Tattoo Inks Banned in the Market

    Sepehri, M., Lerche, C. M., Hutton Carlsen, K. & Serup, J., 2017, In: Dermatology. 233, 1, p. 94-99 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Tattoo Pigments Are Observed in the Kupffer Cells of the Liver Indicating Blood-Borne Distribution of Tattoo Ink

    Sepehri, M., Sejersen, T., Qvortrup, K., Lerche, C. M. & Serup, J., 2017, In: Dermatology. 233, 1, p. 86-93 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2016
  31. Published

    Repeated treatments with ingenol mebutate for prophylaxis of UV-induced squamous cell carcinoma in hairless mice

    Erlendsson, A. M., Thaysen-Petersen, D., Bay, C., Lerche, C. M., Philipsen, P. A., Wulf, H. C., Zibert, J. R. & Hædersdal, M., Oct 2016, In: Journal of Photochemistry and Photobiology B: Biology. 163, p. 144-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Fractional laser-assisted drug delivery: Laser channel depth influences biodistribution and skin deposition of methotrexate

    Taudorf, E. H., Lerche, C. M., Erlendsson, A. M., Philipsen, P. A., Hansen, S. H., Janfelt, C., Paasch, U., Anderson, R. R. & Haedersdal, M., Jul 2016, In: Lasers in Surgery and Medicine. 48, 5, p. 519-29 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Is the thin layer of methyl aminolevulinate used during photodynamic therapy sufficient?

    Wiegell, S. R., Lerche, C. M. & Wulf, H. C., Mar 2016, In: Photodermatology, Photoimmunology & Photomedicine. 32, 2, p. 88-92 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Alternatives to Outdoor Daylight Illumination for Photodynamic Therapy--Use of Greenhouses and Artificial Light Sources

    Lerche, C. M., Heerfordt, I. M., Heydenreich, J. & Wulf, H. C., 29 Feb 2016, In: International Journal of Molecular Sciences. 17, 3, p. 309

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Acute Ultraviolet Radiation Perturbs Epithelialization but not the Biomechanical Strength of Full-thickness Cutaneous Wounds

    Danielsen, P. L., Lerche, C. M., Wulf, H. C., Jorgensen, L. N., Liedberg, A-S. H., Hansson, C. & Ågren, S. P. M., Jan 2016, In: Photochemistry and Photobiology. 92, 1, p. 187-92 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Skin tumor development after UV irradiation and photodynamic therapy is unaffected by short-term pretreatment with 5-fluorouracil, imiquimod and calcipotriol. An experimental hairless mouse study

    Bay, C., Togsverd-Bo, K., Lerche, C. M. & Haedersdal, M., Jan 2016, In: Journal of Photochemistry and Photobiology B: Biology. 154, p. 34-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. 2015
  38. Published

    Black tattoos protect against UVR-induced skin cancer in mice

    Lerche, C. M., Sepehri, M., Serup, J., Poulsen, T. & Wulf, H. C., Sep 2015, In: Photodermatology, Photoimmunology & Photomedicine Online. 31, 5, p. 261-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Topically applied methotrexate is rapidly delivered into skin by fractional laser ablation

    Taudorf, E. H., Lerche, C. M., Vissing, A-C., Philipsen, P. A., Hannibal, J., D'Alvise, J., Hansen, S. H., Janfelt, C., Paasch, U., Anderson, R. R. & Haedersdal, M., Jul 2015, In: Expert Opinion on Drug Delivery. 12, 7, p. 1059-69 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Correlation between treatment time, photobleaching, inflammation and pain after photodynamic therapy with methyl aminolevulinate on tape-stripped skin in healthy volunteers

    Lerche, C. M., Fabricius, S., Philipsen, P. A. & Wulf, H. C., May 2015, In: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. 14, 5, p. 875-82 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Calcipotriol pretreatment enhances methyl aminolevulinate-induced protoporphyrin IX: an in vivo study in hairless mice

    Bay, C., Lerche, C. M., Togsverd-Bo, K., Wulf, H. C. & Haedersdal, M., Jan 2015, In: Photodermatology, Photoimmunology & Photomedicine Online. 31, 1, p. 57-60 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. 2014
  43. Published

    miR-125b induces cellular senescence in malignant melanoma

    Nyholm, A. M., Lerche, C. M., Manfé, V., Biskup, E., Johansen, P., Morling, N., Thomsen, I. B. M., Glud, M. & Gniadecki, R., 24 Apr 2014, In: B M C Dermatology. 14, 8, p. 8

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. 2013
  45. Published

    Artificial daylight photodynamic therapy with "non-inflammatory" doses of hexyl aminolevulinate only marginally delays SCC development in UV-exposed hairless mice

    Togsverd-Bo, K., Lerche, C. M., Philipsen, P. A., Hædersdal, M. & Wulf, H. C., Dec 2013, In: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. 12, 12, p. 2130-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    X-rays and photocarcinogenesis in hairless mice

    Lerche, C. M., Philipsen, P. A. & Wulf, H. C., Aug 2013, In: Archives of Dermatological Research. 305, 6, p. 529-33 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Validation of self-reported erythema: comparison of self-reports, researcher assessment and objective measurements in sun worshippers and skiers

    Petersen, B., Thieden, E., Lerche, C. M. & Wulf, H. C., Feb 2013, In: Journal of the European Academy of Dermatology and Venereology : JEADV. 27, 2, p. 214-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    The relation between methyl aminolevulinate concentration and inflammation after photodynamic therapy in healthy volunteers.

    Fabricius, S., Lerche, C. M., Philipsen, P. A. & Wulf, H. C. O., Jan 2013, In: Photochemical & Photobiological Sciences. 12, 1, p. 117-123 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. 2012
  50. Published

    miR-122 regulates p53/Akt signalling and the chemotherapy-induced apoptosis in cutaneous T-cell lymphoma

    Manfè, V., Biskup, E., Rosbjerg, A., Kamstrup, M., Guldhammer Skov, A., Lerche, C. M., Lauenborg, B. T., Odum, N. & Gniadecki, R., 2012, In: P L o S One. 7, 1, p. e29541

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Neonatal mice do not have increased sensitivity to induction of squamous cell carcinomas

    Lerche, C. M., Poulsen, T. & Wulf, H. C., 2012, In: Photodermatology, Photoimmunology & Photomedicine. 28, 1, p. 26-33 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Porphyrin biodistribution in UV-exposed murine skin after methyl- and hexyl-aminolevulinate incubation

    Togsverd-Bo, K., Lerche, C. M., Philipsen, P. A., Poulsen, T., Wulf, H. C. & Haedersdal, M., 2012, In: Experimental Dermatology. 21, 4, p. 260-264 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Topical nutlin-3a does not decrease photocarcinogenesis induced by simulated solar radiation in hairless mice

    Lerche, C. M., Philipsen, P. A., Poulsen, T., Gniadecki, R. & Wulf, H. C., 2012, In: Photodermatology, Photoimmunology & Photomedicine Online. 28, 4, p. 207-12 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. 2011
  55. Published

    High death rate in mice treated topically with diclofenac

    Lerche, C. M., Philipsen, P. A., Poulsen, T. & Wulf, H. C., 2011, In: Experimental Dermatology. 20, 4, p. 336-8 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. 2010
  57. Published

    Topical hydrocortisone, clobetasol propionate, and calcipotriol do not increase photocarcinogenesis induced by simulated solar irradiation in hairless mice

    Lerche, C. M., Philipsen, P. A., Poulsen, T. & Wulf, H. C., 1 Nov 2010, In: Experimental Dermatology. 19, 11, p. 973-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Photodynamic therapy with topical methyl- and hexylaminolevulinate for prophylaxis and treatment of UV-induced SCC in hairless mice

    Togsverd-Bo, K., Lerche, C. M., Poulsen, T., Wulf, H. C. & Haedersdal, M., 1 Aug 2010, In: Experimental Dermatology. 19, 8, p. e166-72

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Photocarcinogenicity of selected topical dermatological drugs - Studies in hairless mice

    Lerche, C., 14 Jul 2010

    Research output: Book/Report › Doctoral thesis › Research

  60. Published

    Photocarcinogenesis and toxicity of benzoyl peroxide in hairless mice after simulated solar radiation

    Lerche, C. M., Philipsen, P. A., Poulsen, T. & Wulf, H. C., 1 Apr 2010, In: Experimental Dermatology. 19, 4, p. 381-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Photocarcinogenicity of selected topically applied dermatological drugs: calcineurin inhibitors, corticosteroids, and vitamin D analogs

    Lerche, C. & Wulf, H. C. O., 2010, In: Dermatology Reports. 2, 2

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Topical nutlin-3 potentiates the UVB-induced p53 response and reduces DNA photodamage and apoptosis in mouse epidermal keratinocytes in vivo

    Lerche, C., Thomsen, I. B. M., Wulf, H. C. O. & Gniadecki, R., 2010, In: Journal of Clinical & Experimental Dermatology Research. 1, 106

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. 2009
  64. Published

    Reduced ultraviolet irradiation delays subsequent squamous cell carcinomas in hairless mice.

    Togsverd-Bo, K., Lerche, C. M., Poulsen, T., Hædersdal, M. & Wulf, H. C. O., 2009, In: Photodermatology, Photoimmunology & Photomedicine. 25, 6, p. 305-309

    Research output: Contribution to journal › Journal article › Research › peer-review

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