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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2021
  2. E-pub ahead of print

    Relapse risk following truncation of PEG-asparaginase in childhood acute lymphoblastic leukemia

    Gottschalk Højfeldt, S., Grell, K., Abrahamsson, J., Lund, B., Vettenranta, K., Jonsson, O. G., Frandsen, T. L., Wolthers, B. O., Marquart, H. V. H., Vaitkeviciene, G., Lepik, K., Heyman, M., Schmiegelow, K. & Albertsen, B. K., 2021, (E-pub ahead of print) In: Blood.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2020
  4. Published

    Effects of germline DHFR and FPGS variants on methotrexate metabolism and relapse of leukemia

    Tulstrup, M., Moriyama, T., Jiang, C., Grosjean, M., Nersting, J., Abrahamsson, J., Grell, K., Hjalgrim, L. L., Jónsson, Ó. G., Kanerva, J., Lund, B., Nielsen, S. N., Nielsen, R. L., Overgaard, U., Quist-Paulsen, P., Pruunsild, K., Vaitkeviciene, G., Wolthers, B. O., Zhang, H., Gupta, R., Yang, J. J. & Schmiegelow, K., 3 Sep 2020, In: Blood. 136, 10, p. 1161-1168 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Increasing completion of asparaginase treatment in childhood acute lymphoblastic leukaemia (ALL): summary of an expert panel discussion

    Baruchel, A., Brown, P., Rizzari, C., Silverman, L., van der Sluis, I., Wolthers, B. O. & Schmiegelow, K., Sep 2020, In: ESMO Open. 5, 5, p. e000977

    Research output: Contribution to journalReviewpeer-review

  6. Published

    Genome-Wide Association Meta-Analysis of Single-Nucleotide Polymorphisms and Symptomatic Venous Thromboembolism during Therapy for Acute Lymphoblastic Leukemia and Lymphoma in Caucasian Children

    Mateos, M. K., Tulstrup, M., Quinn, M. C., Tuckuviene, R., Marshall, G. M., Gupta, R., Mayoh, C., Wolthers, B. O., Barbaro, P. M., Ruud, E., Sutton, R., Huttunen, P., Revesz, T., Trakymiene, S. S., Barbaric, D., Tedgård, U., Giles, J. E., Alvaro, F., Jonsson, O. G., Mechinaud, F., Saks, K., Catchpoole, D., Kotecha, R. S., Dalla-Pozza, L., Chenevix-Trench, G., Trahair, T. N., MacGregor, S. & Schmiegelow, K., 19 May 2020, In: Cancers. 12, 5

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Dyslipidemia at diagnosis of childhood acute lymphoblastic leukemia

    Mogensen, P. R., Grell, K., Schmiegelow, K., Overgaard, U. M., Wolthers, B. O., Mogensen, S. S., Vaag, A. & Frandsen, T. L., 6 Apr 2020, In: PLoS One. 15, 4, e0231209.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Asparaginase-Associated Pancreatitis in Acute Lymphoblastic Leukemia: Results From the NOPHO ALL2008 Treatment of Patients 1-45 Years of Age

    Rank, C. U., Wolthers, B. O., Grell, K., Albertsen, B. K., Frandsen, T. L., Overgaard, U. M., Toft, N., Nielsen, O. J., Wehner, P. S., Harila-Saari, A., Heyman, M. M., Malmros, J., Abrahamsson, J., Norén-Nyström, U., Tomaszewska-Toporska, B., Lund, B., Jarvis, K. B., Quist-Paulsen, P., Vaitkevičienė, G. E., Griškevičius, L., Taskinen, M., Wartiovaara-Kautto, U., Lepik, K., Punab, M., Jónsson, Ó. G. & Schmiegelow, K., 1 Jan 2020, In: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 38, 2, p. 145-154 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2019
  10. Published

    Insulin-dependent diabetes: A chronic complication to acute pancreatitis in childhood acute lymphoblastic leukemia

    Wolthers, B. O., Mogensen, P. R., Frandsen, T. L., Abrahamsson, J., Behrendtz, M., Heyman, M., Lohi, O., Norén-Nyström, U., Ruud, E. & Schmiegelow, K., 1 Jan 2019, In: Pediatric Blood & Cancer. 66, 1, p. e27437

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Genetic predisposition to PEG-asparaginase hypersensitivity in children treated according to NOPHO ALL2008

    Højfeldt, S. G., Wolthers, B. O., Tulstrup, M., Abrahamsson, J., Gupta, R., Harila-Saari, A., Heyman, M., Henriksen, L. T., Jónsson, Ò. G., Lähteenmäki, P. M., Lund, B., Pruunsild, K., Vaitkeviciene, G., Schmiegelow, K., Albertsen, B. K. & Nordic Society of Paediatric Haematology Oncology (NOPHO) group, 2019, In: British Journal of Haematology. 184, 3, p. 405-417 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Intermittent Versus Continuous PEG-Asparaginase to Reduce Asparaginase-Associated Toxicities: A NOPHO ALL2008 Randomized Study

    Albertsen, B. K., Grell, K., Abrahamsson, J., Lund, B., Vettenranta, K., Jónsson, Ó. G., Frandsen, T. L., Wolthers, B. O., Heyman, M. & Schmiegelow, K., 2019, In: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 37, 19, p. 1638-1646 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Trypsin-encoding PRSS1-PRSS2 variations influence the risk of asparaginase-associated pancreatitis in children with acute lymphoblastic leukemia: a Ponte di Legno toxicity working group report

    Wolthers, B. O., Frandsen, T. L., Patel, C. J., Abaji, R., Attarbaschi, A., Barzilai, S., Colombini, A., Escherich, G., Grosjean, M., Krajinovic, M., Larsen, E., Liang, D-C., Möricke, A., Rasmussen, K. K., Samarasinghe, S., Silverman, L. B., van der Sluis, I. M., Stanulla, M., Tulstrup, M., Yadav, R., Yang, W., Zapotocka, E., Gupta, R. & Schmiegelow, K., 2019, In: Haematologica. 104, 3, p. 556-563 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2018
  15. Published

    NT5C2 germline variants alter thiopurine metabolism and are associated with acquired NT5C2 relapse mutations in childhood acute lymphoblastic leukaemia

    Tulstrup, M., Grosjean, M., Nielsen, S. N., Grell, K., Wolthers, B. O., Wegener, P. S., Jonsson, O. G., Lund, B., Harila-Saari, A., Abrahamsson, J., Vaitkeviciene, G., Pruunsild, K., Toft, N., Holm, M., Hulegårdh, E., Liestøl, S., Griskevicius, L., Punab, M., Wang, J., Carroll, W. L., Zhang, Z., Dalgaard, M. D., Gupta, R., Nersting, J. & Schmiegelow, K., Dec 2018, In: Leukemia. 32, 12, p. 2527-2535 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Association between body mass index and pancreatitis in children with acute lymphoblastic leukemia

    Mogensen, P. R., Wolthers, B. O., Grell, K., Schmiegelow, K. & Frandsen, T. L., Aug 2018, In: Pediatric Blood & Cancer. 65, 8, p. e27071

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published
  18. 2017
  19. Published

    Asparaginase-associated pancreatitis in childhood acute lymphoblastic leukaemia: an observational Ponte di Legno Toxicity Working Group study

    Wolthers, B. O., Frandsen, T. L., Baruchel, A., Attarbaschi, A., Barzilai, S., Colombini, A., Escherich, G., Grell, K., Inaba, H., Kovacs, G., Liang, D-C., Mateos, M., Mondelaers, V., Möricke, A., Ociepa, T., Samarasinghe, S., Silverman, L. B., van der Sluis, I. M., Stanulla, M., Vrooman, L. M., Yano, M., Zapotocka, E., Schmiegelow, K. & Ponte di Legno Toxicity Working Group, Sep 2017, In: Lancet Oncology. 18, 9, p. 1238-1248 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Asparaginase-associated pancreatitis: a study on phenotype and genotype in the NOPHO ALL2008 protocol

    Wolthers, B. O., Frandsen, T. L., Abrahamsson, J., Albertsen, B. K., Helt, L. R., Heyman, M., Jónsson, Ó. G., Kõrgvee, L. T., Lund, B., Raja, R. A., Rasmussen, K. K., Taskinen, M., Tulstrup, M., Vaitkevičienė, G. E., Yadav, R., Gupta, R. & Schmiegelow, K., Feb 2017, In: Leukemia. 31, 2, p. 325-332 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published
  22. 2015
  23. Published

    Varicella-zoster-infektion kompliceret med bakteriel pneumoni hos barn

    Wolthers, B. O., Thiested, E. & Gyhrs, A. F., 26 Jan 2015, In: Ugeskrift for Laeger. 177, 2A, p. 10-1 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 46276530