Research output per year
Research output per year
- 46 results
Search results
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2024
Allogeneic mesenchymal stem cell therapy for dry eye disease in patients with Sjögren's syndrome: A randomized clinical trial
Møller-Hansen, M., Larsen, A.-C., Wiencke, A. K., Terslev, L., Siersma, V., Andersen, T. T., Hansen, A. E., Bruunsgaard, H., Haack-Sørensen, M., Ekblond, A., Kastrup, J., Utheim, T. P. & Heegaard, S., Jan 2024, In: The ocular surface. 31, p. 1-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
3 Citations (Scopus) -
Early Detection of Cardiotoxicity Using [64Cu]Cu-NODAGA-E[(cRGDyK)]2 PET Imaging in a Rat Model of Doxorubicin-Induced Heart Failure
Hoeeg, C., Follin, B., Grandjean, C. E., Ripa, R. S., Ekblond, A., Kastrup, J., Binderup, T. & Kjaer, A., 5 Aug 2024, In: Molecular Pharmaceutics. 21, 8, p. 3909-3920 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Investigating the paracrine and juxtacrine abilities of adipose-derived stromal cells in angiogenesis triple cell co-cultures
Harary Søndergaard, R., Drozd Højgaard, L., Haack-Sørensen, M., Hoeeg, C., Mønsted Johansen, E., Follin, B., Kastrup, J., Ekblond, A. & Juhl, M., Jun 2024, In: Stem Cell Research. 77, 103417.Research output: Contribution to journal › Journal article › Research › peer-review
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Mesenchymal Stem/Stromal Cell Therapy for Radiation-Induced Xerostomia in Previous Head and Neck Cancer Patients: A Phase II Randomized, Placebo-Controlled Trial
Jakobsen, K., Carlander, A.-L. F., Todsen, T., Melchiors, J., Paaske, N., Østergaard Madsen, A. K., Kloch Bendtsen, S., Mordhorst, C., Stampe, H., Kastrup, J., Ekblond, A., Haack-Sørensen, M., Farhadi, M., Maare, C., Friborg, J., Duch Lynggaard, C., Werner Hauge, A., Christensen, R., Grønhøj, C. & von Buchwald, C., 15 May 2024, In: Clinical Cancer Research. 30, 10, p. 2078-2084 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mesenchymal stromal cells to treat patients with non-ischaemic heart failure: Results from SCIENCE II pilot study
Qayyum, A. A., Frljak, S., Juhl, M., Poglajen, G., Zemljičl, G., Cerar, A., Litman, T., Ekblond, A., Haack-Sørensen, M., Højgaard, L. D., Kastrup, J. & Vrtovec, B., Dec 2024, In: ESC Heart Failure. 11, 6, p. 3882-3891 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2023
[68Ga]Ga-NODAGA-E[(cRGDyK)]2 and [64Cu]Cu-DOTATATE PET Predict Improvement in Ischemic Cardiomyopathy
Follin, B., Hoeeg, C., Hunter, I., Bentsen, S., Juhl, M., Jensen, J. K., Binderup, T., Nielsen, C. H., Ripa, R. S., Kastrup, J., Ekblond, A. & Kjaer, A., 11 Jan 2023, In: Diagnostics. 13, 2, 268.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
Danish phase II trial using adipose tissue derived mesenchymal stromal cells for patients with ischaemic heart failure
Qayyum, A. A., Mouridsen, M., Nilsson, B., Gustafsson, I., Schou, M., Nielsen, O. W., Hove, J. D., Mathiasen, A. B., Jørgensen, E., Helqvist, S., Joshi, F. R., Johansen, E. M., Follin, B., Juhl, M., Højgaard, L. D., Haack-Sørensen, M., Ekblond, A. & Kastrup, J., Apr 2023, In: ESC Heart Failure. 10, 2, p. 1170-1183 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
16 Citations (Scopus) -
Effectiveness and safety of mesenchymal stem/stromal cell for radiation-induced hyposalivation and xerostomia in previous head and neck cancer patients (MESRIX-III): a study protocol for a single-centre, double-blinded, randomised, placebo-controlled, phase II study
Jakobsen, K. K., Carlander, A.-L. F., Grønhøj, C., Todsen, T., Melchiors, J., Paaske, N., Madsen, A. K. Ø., Kastrup, J., Ekblond, A., Haack-Sørensen, M., Farhadi, M., Maare, C., Friborg, J., Lynggard, C. D. & von Buchwald, C., 1 Sept 2023, In: Trials. 24, 1, 567.Research output: Contribution to journal › Journal article › Research › peer-review
4 Citations (Scopus) -
Effect of allogeneic adipose tissue-derived mesenchymal stromal cell treatment in chronic ischaemic heart failure with reduced ejection fraction - the SCIENCE trial
Qayyum, A. A., van Klarenbosch, B., Frljak, S., Cerar, A., Poglajen, G., Traxler-Weidenauer, D., Nadrowski, P., Paitazoglou, C., Vrtovec, B., Bergmann, M. W., Chamuleau, S. A. J., Wojakowski, W., Gyöngyösi, M., Kraaijeveld, A., Hansen, K. S., Vrangbaek, K., Jørgensen, E., Helqvist, S., Joshi, F. R. & Johansen, E. M. & 8 others, , Apr 2023, In: European Journal of Heart Failure. 25, 4, p. 576-587 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
25 Citations (Scopus) -
2022
Adipose-derived stromal cells increase the formation of collagens through paracrine and juxtacrine mechanisms in a fibroblast co-culture model utilizing macromolecular crowding
Søndergaard, R. H., Højgaard, L. D., Reese-Petersen, A. L., Hoeeg, C., Mathiasen, A. B., Haack-Sørensen, M., Follin, B., Genovese, F., Kastrup, J., Juhl, M. & Ekblond, A., 11 Jun 2022, In: Stem Cell Research & Therapy. 13, 1, p. 250 250.Research output: Contribution to journal › Journal article › Research › peer-review
5 Citations (Scopus) -
Functional in vitro models of the inhibitory effect of adipose tissue-derived stromal cells on lymphocyte proliferation: Improved sensitivity and quantification through flow cytometric analysis
Juhl, M., Follin, B., Christensen, J. P., Kastrup, J. & Ekblond, A., Nov 2022, In: Journal of Immunological Methods. 510, 113360.Research output: Contribution to journal › Journal article › Research › peer-review
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GMP Compliant Production of a Cryopreserved Adipose-Derived Stromal Cell Product for Feasible and Allogeneic Clinical Use
Haack-Sørensen, M., Johansen, E. M., Højgaard, L. D., Kastrup, J. & Ekblond, A., 2022, In: Stem Cells International. 2022, p. 1-12 12 p., 4664917.Research output: Contribution to journal › Journal article › Research › peer-review
14 Citations (Scopus) -
Intraglandular mesenchymal stem cell treatment induces changes in the salivary proteome of irradiated patients
Lynggaard, C. D., Jersie-Christensen, R., Juhl, M., Jensen, S. B., Grønhøj, C., Melchiors, J., Jacobsen, S., Møller-Hansen, M., Herly, M., Ekblond, A., Kastrup, J., Fischer-Nielsen, A., Belstrøm, D. & von Buchwald, C., 10 Dec 2022, In: Communications medicine. 2, 1, p. 160 160.Research output: Contribution to journal › Journal article › Research › peer-review
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Intraglandular Off-the-Shelf Allogeneic Mesenchymal Stem Cell Treatment in Patients with Radiation-Induced Xerostomia: A Safety Study (MESRIX-II)
Lynggaard, C. D., Grønhøj, C., Christensen, R., Fischer-Nielsen, A., Melchiors, J., Specht, L., Andersen, E., Mortensen, J., Oturai, P., Barfod, G. H., Haastrup, E. K., Møller-Hansen, M., Haack-Sørensen, M., Ekblond, A., Kastrup, J., Jensen, S. B. & von Buchwald, C., 27 May 2022, In: Stem Cells Translational Medicine. 11, 5, p. 478-489 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
26 Citations (Scopus) -
Optimizing an immunomodulatory potency assay for Mesenchymal Stromal Cell
Hansen, S. B., Højgaard, L. D., Kastrup, J., Ekblond, A., Follin, B. & Juhl, M., 2022, In: Frontiers in Immunology. 13, p. 1-12 12 p., 1085312.Research output: Contribution to journal › Journal article › Research › peer-review
10 Citations (Scopus) -
2021
Cryopreservation of peripheral blood mononuclear cells for use in proliferation assays: First step towards potency assays
Juhl, M., Christensen, J. P., Pedersen, A. E., Kastrup, J. & Ekblond, A., Jan 2021, In: Journal of Immunological Methods. 488, p. 112897 112897.Research output: Contribution to journal › Journal article › Research › peer-review
8 Citations (Scopus) -
Safety and feasibility of mesenchymal stem cell therapy in patients with aqueous deficient dry eye disease
Møller-Hansen, M., Larsen, A.-C., Toft, P. B., Lynggaard, C. D., Schwartz, C., Bruunsgaard, H., Haack-Sørensen, M., Ekblond, A., Kastrup, J. & Heegaard, S., Jan 2021, In: The ocular surface. 19, p. 43-52 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
44 Citations (Scopus) -
The Initial Cardiac Tissue Response to Cryopreserved Allogeneic Adipose Tissue-Derived Mesenchymal Stromal Cells in Rats with Chronic Ischemic Cardiomyopathy
Follin, B., Hoeeg, C., Højgaard, L. D., Juhl, M., Lund, K. B., Døssing, K. B. V., Bentsen, S., Hunter, I., Nielsen, C. H., Ripa, R. S., Kastrup, J., Ekblond, A. & Kjaer, A., 29 Oct 2021, In: International Journal of Molecular Sciences. 22, 21, 11758.Research output: Contribution to journal › Journal article › Research › peer-review
6 Citations (Scopus) -
2020
Adipose Tissue-Derived Stromal Cells Induce a Highly Trophic Environment While Reducing Maturation of Monocyte-Derived Dendritic Cells
Juhl, M., Follin, B., Gad, M., Larsen, J., Kastrup, J. & Ekblond, A., 2020, In: Stem Cells International. 2020, p. 8868909Research output: Contribution to journal › Journal article › Research › peer-review
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Bone marrow-derived mesenchymal stromal cell treatment in patients with ischaemic heart failure: final 4-year follow-up of the MSC-HF trial
Mathiasen, A. B., Qayyum, A. A., Jørgensen, E., Helqvist, S., Kofoed, K. F., Haack-Sørensen, M., Ekblond, A. & Kastrup, J., May 2020, In: European Journal of Heart Failure. 22, 5, p. 884-892 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
94 Citations (Scopus) -
Efficacy and Mode of Action of Mesenchymal Stem Cells in Non-Ischemic Dilated Cardiomyopathy: A Systematic Review
Hoeeg, C., Frljak, S., Qayyum, A. A., Vrtovec, B., Kastrup, J., Ekblond, A. & Follin, B., 5 Dec 2020, In: Biomedicines. 8, 12Research output: Contribution to journal › Review › peer-review
14 Citations (Scopus) -
2019
Autologous adipose-derived stromal cell treatment for patients with refractory angina (MyStromalCell Trial): 3-years follow-up results
Qayyum, A. A., Mathiasen, A. B., Helqvist, S., Jørgensen, E., Haack-Sørensen, M., Ekblond, A. & Kastrup, J., 12 Nov 2019, In: Journal of Translational Medicine. 17, 1, p. 360Research output: Contribution to journal › Journal article › Research › peer-review
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In Vivo MRI Tracking of Mesenchymal Stromal Cells Labeled with Ultrasmall Paramagnetic Iron Oxide Particles after Intramyocardial Transplantation in Patients with Chronic Ischemic Heart Disease
Mathiasen, A. B., Qayyum, A. A., Jørgensen, E., Helqvist, S., Ekblond, A., Ng, M., Bhakoo, K. & Kastrup, J., 2019, In: Stem Cells International. 2019, p. 2754927Research output: Contribution to journal › Journal article › Research › peer-review
23 Citations (Scopus) -
Rationale and design of the European multicentre study on Stem Cell therapy in IschEmic Non-treatable Cardiac diseasE (SCIENCE)
Paitazoglou, C., Bergmann, M. W., Vrtovec, B., Chamuleau, S. A. J., van Klarenbosch, B., Wojakowski, W., Michalewska-Włudarczyk, A., Gyöngyösi, M., Ekblond, A., Haack-Sørensen, M., Jaquet, K., Vrangbaek, K., Kastrup, J. & SCIENCE Investigators, 1 Jan 2019, In: European Journal of Heart Failure. 21, 8, p. 1032-1041 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
41 Citations (Scopus) -
2018
Development of large-scale manufacturing of adipose-derived stromal cells for clinical applications using bioreactors and human platelet lysate
Haack-Sørensen, M., Juhl, M., Follin, B., Harary Søndergaard, R., Kirchhoff, M., Kastrup, J. & Ekblond, A., Jul 2018, In: Scandinavian Journal of Clinical and Laboratory Investigation. 78, 4, p. 293-300 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
43 Citations (Scopus) -
Retention and Functional Effect of Adipose-Derived Stromal Cells Administered in Alginate Hydrogel in a Rat Model of Acute Myocardial Infarction
Follin, B., Ghotbi, A. A., Clemmensen, A. E., Bentsen, S., Juhl, M., Søndergaard, R. H., Lund, L. D., Haack-Sørensen, M., Hasbak, P., Cohen, S., Ripa, R. S., Kastrup, J., Ekblond, A. & Kjær, A., 2018, In: Stem Cells International. 2018, p. 7821461Research output: Contribution to journal › Journal article › Research › peer-review
14 Citations (Scopus) -
2017
Adipose-Derived Stromal Cells for Treatment of Patients with Chronic Ischemic Heart Disease (MyStromalCell Trial): A Randomized Placebo-Controlled Study
Qayyum, A. A., Mathiasen, A. B., Mygind, N. D., Kühl, J. T., Jørgensen, E., Helqvist, S., Elberg, J. J., Kofoed, K. F., Vejlstrup, N. G., Fischer-Nielsen, A., Haack-Sørensen, M., Ekblond, A. & Kastrup, J., 2017, In: Stem Cells International. 2017, p. e5237063Research output: Contribution to journal › Journal article › Research › peer-review
44 Citations (Scopus) -
Cryopreserved Off-the-Shelf Allogeneic Adipose-Derived Stromal Cells for Therapy in Patients with Ischemic Heart Disease and Heart Failure-A Safety Study
Kastrup, J., Haack-Sørensen, M., Juhl, M., Harary Søndergaard, R., Follin, B., Drozd Lund, L., Mønsted Johansen, E., Ali Qayyum, A., Bruun Mathiasen, A., Jørgensen, E., Helqvist, S., Jørgen Elberg, J., Bruunsgaard, H. & Ekblond, A., Nov 2017, In: Stem Cells Translational Medicine. 6, 11, p. 1963-1971 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
85 Citations (Scopus) -
Influence of patient related factors on number of mesenchymal stromal cells reached after in vitro culture expansion for clinical treatment
Qayyum, A. A., Kaur, K. P., Mathiasen, A. B., Haack-Sørensen, M., Ekblond, A. & Kastrup, J., Nov 2017, In: Scandinavian Journal of Clinical and Laboratory Investigation. 77, 7, p. 541-548 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
8 Citations (Scopus) -
Rationale and Design of the First Double-Blind, Placebo-Controlled Trial with Allogeneic Adipose Tissue-Derived Stromal Cell Therapy in Patients with Ischemic Heart Failure: A Phase II Danish Multicentre Study
Kastrup, J., Schou, M., Gustafsson, I., Nielsen, O. W., Møgelvang, R., Kofoed, K. F., Kragelund, C., Hove, J. D., Fabricius-Bjerre, A., Heitman, M., Haack-Sørensen, M., Lund, L. D., Johansen, E. M., Qayyum, A. A., Mathiasen, A. B. & Ekblond, A., 2017, In: Stem Cells International. 2017, p. 8506370 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
25 Citations (Scopus) -
Senescence and quiescence in adipose-derived stromal cells: Effects of human platelet lysate, fetal bovine serum and hypoxia
Søndergaard, R. H., Follin, B., Lund, L. D., Juhl, M., Ekblond, A., Kastrup, J. & Haack-Sørensen, M., Jan 2017, In: Cytotherapy. 19, 1, p. 95-106 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
26 Citations (Scopus) -
2016
Comparison of clinical grade human platelet lysates for cultivation of mesenchymal stromal cells from bone marrow and adipose tissue
Juhl, M., Tratwal, J., Follin, B., Søndergaard, R. H., Kirchhoff, E. M., Ekblond, A., Kastrup, J. & Haack-Sørensen, M., 2016, In: Scandinavian Journal of Clinical and Laboratory Investigation. 76, 2, p. 93-104 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
42 Citations (Scopus) -
Cryopreservation and Revival of Human Mesenchymal Stromal Cells
Haack-Sørensen, M., Ekblond, A. & Kastrup, J., 2016, In: Methods in molecular biology. 1416, p. 357-74 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
9 Citations (Scopus) -
Culture expansion of adipose derived stromal cells. A closed automated Quantum Cell Expansion System compared with manual flask-based culture
Haack-Sørensen, M., Follin, B., Juhl, M., Brorsen, S. K., Søndergaard, R. H., Kastrup, J. & Ekblond, A., 16 Nov 2016, In: Journal of Translational Medicine. 14, 1, p. 319 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
49 Citations (Scopus) -
Increased Paracrine Immunomodulatory Potential of Mesenchymal Stromal Cells in Three-Dimensional Culture
Follin, B., Juhl, M., Cohen, S., Perdersen, A. E., Kastrup, J. & Ekblond, A., Aug 2016, In: Tissue engineering. Part B, Reviews. 22, 4, p. 322-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
93 Citations (Scopus) -
Mesenchymal stromal cell therapy in ischemic heart disease
Kastrup, J., Mygind, N. D., Qayyum, A. A., Mathiasen, A. B., Haack-Sørensen, M. & Ekblond, A., 7 Jul 2016, In: Scandinavian cardiovascular journal : SCJ. 50, 5-6, p. 293-299 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
13 Citations (Scopus) -
2015
Bone marrow-derived mesenchymal stromal cell treatment in patients with severe ischaemic heart failure: a randomized placebo-controlled trial (MSC-HF trial)
Mathiasen, A. B., Qayyum, A. A., Jørgensen, E., Helqvist, S., Fischer-Nielsen, A., Kofoed, K. F., Haack-Sørensen, M., Ekblond, A. & Kastrup, J., 14 Jul 2015, In: European Heart Journal. 36, 27, p. 1744-53 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
270 Citations (Scopus) -
Human adipose-derived stromal cells in a clinically applicable injectable alginate hydrogel: Phenotypic and immunomodulatory evaluation
Follin, B., Juhl, M., Cohen, S., Pedersen, A. E., Gad, M., Kastrup, J. & Ekblond, A., Aug 2015, In: Cytotherapy. 17, 8, p. 1104-18 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
49 Citations (Scopus) -
Influence of vascular endothelial growth factor stimulation and serum deprivation on gene activation patterns of human adipose tissue-derived stromal cells
Tratwal, J., Mathiasen, A. B., Juhl, M., Brorsen, S. K., Kastrup, J. & Ekblond, A., 2015, In: Stem Cell Research & Therapy. 6, p. 62Research output: Contribution to journal › Journal article › Research › peer-review
29 Citations (Scopus) -
2014
Clinical gene and stem cell therapy in patients with acute and chronic myocardial ischemia.
Kastrup, J., Ekblond, A., Haack-Sørensen, M., Mathiasen, A. B. & Qayyum, A. A., 2014, Adult and pluripotent stem cells. Hescheler, J. & Hofer, E. (eds.). Netherlands: Springer Science + Business Media Dordrecht, p. 143-68 21 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Identification of a common reference gene pair for qPCR in human mesenchymal stromal cells from different tissue sources treated with VEGF
Tratwal, J., Follin, B., Ekblond, A., Kastrup, J. & Haack-Sørensen, M., 2014, In: B M C Molecular Biology. 15, p. 11Research output: Contribution to journal › Journal article › Research › peer-review
31 Citations (Scopus) -
Ultrastructural characterization of mesenchymal stromal cells labeled with ultrasmall superparamagnetic iron-oxide nanoparticles for clinical tracking studies
Hansen, L., Hansen, A. B., Mathiasen, A. B., Ng, M., Bhakoo, K., Ekblond, A., Kastrup, J. & Friis, T., Aug 2014, In: Scandinavian Journal of Clinical & Laboratory Investigation. 74, 5, p. 437-46 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
12 Citations (Scopus) -
2013
Direct intramyocardial mesenchymal stromal cell injections in patients with severe refractory angina - one year follow-up
Haack-Sørensen, M., Friis, T., Mathiasen, A. B., Jørgensen, E., Hansen, L., Dickmeiss, E., Ekblond, A. & Kastrup, J., 2013, In: Cell Transplantation. 22, 3, p. 521-8Research output: Contribution to journal › Journal article › Research › peer-review
54 Citations (Scopus) -
Identical effects of VEGF and serum-deprivation on phenotype and function of adipose-derived stromal cells from healthy donors and patients with ischemic heart disease
Follin, B., Tratwal, J. C. P., Haack-Sørensen, M., Elberg, J. J., Kastrup, J. & Ekblond, A., 2013, In: Journal of Translational Medicine. 11, p. 219Research output: Contribution to journal › Journal article › Research › peer-review
26 Citations (Scopus) -
Labeling of Human Mesenchymal Stromal Cells with Indium-111 for SPECT Imaging
Ripa, R. S., Haack-Sørensen, M., Kastrup, J. & Ekblond, A., 2013, Encyclopedia of Metalloproteins. Springer Publishing CompanyResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Mesenchymal stromal cell phenotype is not influenced by confluence during culture expansion
Haack-Sørensen, M., Hansen, S. K., Hansen, L., Gaster, M., Hyttel, P., Ekblond, A. & Kastrup, J., Feb 2013, In: Stem Cell Reviews. 9, 1, p. 44-58 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
17 Citations (Scopus)