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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2018
  2. Published

    DMRT1 repression using a novel approach to genetic manipulation induces testicular dysgenesis in human fetal gonads

    Macdonald, J., Kilcoyne, K. R., Sharpe, R. M., Kavanagh, Á., Anderson, R. A., Brown, P., Smith, L. B., Jørgensen, A. & Mitchell, R. T. 1 Nov 2018 In : Human reproduction (Oxford, England). 33, 11, p. 2107-2121 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. E-pub ahead of print
  4. E-pub ahead of print

    A young testicular microenvironment protects Leydig cells against age-related dysfunction in a mouse model of premature aging

    Curley, M., Milne, L., Smith, S., Jørgensen, A., Frederiksen, H., Hadoke, P., Potter, P. & Smith, L. B. 6 Aug 2018 In : FASEB Journal. p. fj201800612R

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. E-pub ahead of print

    At the crossroads of fate - somatic cell lineage specification in the fetal gonad

    Rotgers, E., Jørgensen, A. & Yao, H. H-C. 15 May 2018 In : Endocrine Reviews.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Effects of Exposure to Acetaminophen and Ibuprofen on Fetal Germ Cell Development in Both Sexes in Rodent and Human Using Multiple Experimental Systems

    Hurtado-Gonzalez, P., Anderson, R. A., Macdonald, J., van den Driesche, S., Kilcoyne, K., Jørgensen, A., McKinnell, C., Macpherson, S., Sharpe, R. M. & Mitchell, R. T. 16 Apr 2018 In : Environmental Health Perspectives. 126, 4, p. 047006

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. E-pub ahead of print

    Loss of Function of the Nuclear Receptor NR2F2, Encoding COUP-TF2, Causes Testis Development and Cardiac Defects in 46,XX Children

    Bashamboo, A., Eozenou, C., Jorgensen, A., Bignon-Topalovic, J., Siffroi, J-P., Hyon, C., Tar, A., Nagy, P., Sólyom, J., Halász, Z., Paye-Jaouen, A., Lambert, S., Rodriguez-Buritica, D., Bertalan, R., Martinerie, L., Rajpert-De Meyts, E., Achermann, J. C. & McElreavey, K. 16 Feb 2018 In : American Journal of Human Genetics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. E-pub ahead of print

    Experimental models of testicular development and function using human tissue and cells

    Tharmalingam, M. D., Jorgensen, A. & Mitchell, R. T. 6 Jan 2018 In : Molecular and cellular endocrinology.

    Research output: Contribution to journalReviewResearchpeer-review

  9. 2017
  10. Published

    Experimentally induced testicular dysgenesis syndrome originates in the masculinization programming window

    van den Driesche, S., Kilcoyne, K. R., Wagner, I. W., Rebourcet, D., Boyle, A., Mitchell, R., McKinnell, C., Macpherson, S., Donat, R., Shukla, C. J., Jørgensen, A., Rajpert-De Meyts, E., Skakkebæk, N. E. & Sharpe, R. 23 Mar 2017 In : JCI insight. 2, 6, e91204

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Involvement of the DNA mismatch repair system in cisplatin sensitivity of testicular germ cell tumours

    Rudolph, C., Melau, C., Nielsen, J. E., Vile Jensen, K., Liu, D., Pena-Diaz, J., Rajpert-De Meyts, E., Rasmussen, L. J. & Jørgensen, A. 2017 In : Cellular oncology (Dordrecht). 40, 4, p. 341-55

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2015
  13. Published
  14. Published

    Ex vivo culture of human fetal gonads: manipulation of meiosis signalling by retinoic acid treatment disrupts testis development

    Jørgensen, A., Nielsen, J. E., Perlman, S., Lundvall, L., Mitchell, R. T., Juul, A. & Rajpert-De Meyts, E. 6 Aug 2015 In : Human reproduction (Oxford, England). 30, 10, p. 2351-63

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Prolonged exposure to acetaminophen reduces testosterone production by the human fetal testis in a xenograft model

    van den Driesche, S., Macdonald, J., Anderson, R. A., Johnston, Z. C., Chetty, T., Smith, L. B., McKinnell, C., Dean, A., Homer, N. Z., Jorgensen, A., Camacho-Moll, M. E., Sharpe, R. M. & Mitchell, R. T. 20 May 2015 In : Science translational medicine. 7, 288, p. 288ra80

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Biglycan is a novel binding partner of fibroblast growth factor receptor 3c (FGFR3c) in the human testis

    Winge, S. B., Nielsen, J., Jørgensen, A., Owczarek, S., Ewen, K. A., Nielsen, J. E., Juul, A., Berezin, V. & Rajpert-De Meyts, E. 5 Jan 2015 In : Molecular and cellular endocrinology. 399, p. 235-43 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published
  18. 2014
  19. Published

    Interaction between paraoxonase 1 polymorphism and prenatal pesticide exposure on metabolic markers in children using a multiplex approach

    Jørgensen, A., Nellemann, C., Wohlfahrt-Veje, C., Jensen, T. K., Main, K. M. & Andersen, H. R. 22 Nov 2014 In : Reproductive toxicology (Elmsford, N.Y.). 51C, p. 22-30 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Regulation of meiotic entry and gonadal sex differentiation in the human: normal and disrupted signaling

    Jørgensen, A. & Rajpert-De Meyts, E. Aug 2014 In : Biomolecular Concepts. 5, 4, p. 331-41 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Validation of endogenous normalizing genes for expression analyses in adult human testis and germ cell neoplasms

    Svingen, T., Jørgensen, A. & Rajpert-De Meyts, E. Aug 2014 In : Molecular Human Reproduction. 20, 8, p. 709-18 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Hanging drop cultures of human testis and testis cancer samples: a model used to investigate activin treatment effects in a preserved niche

    Jørgensen, A., Young, J., Nielsen, J. E., Joensen, U. N., Toft, B. G., Rajpert-De Meyts, E. & Loveland, K. L. 13 May 2014 In : B J C. 110, 10, p. 2604-14 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published
  24. 2013
  25. Published

    Characterization of the testicular, epididymal and endocrine phenotypes in the Leuven Vdr-deficient mouse model: targeting estrogen signalling

    Blomberg Jensen, M., Lieben, L., Nielsen, J. E., Willems, A., Jørgensen, A., Juul, A., Toppari, J., Carmeliet, G. & Rajpert-De Meyts, E. 5 Sep 2013 In : Molecular and cellular endocrinology. 377, 1-2, p. 93-102 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published
  27. Published

    Dysregulation of the mitosis-meiosis switch in testicular carcinoma in situ

    Jørgensen, A., Nielsen, J. E., Almstrup, K., Toft, B. G., Petersen, B. L. & Rajpert-De Meyts, E. Mar 2013 In : Journal of Pathology. 229, 4, p. 588-98 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published
  29. Published
  30. 2012
  31. Published
  32. Published
  33. Published
  34. Published

    Vitamin D metabolism and effects on pluripotency genes and cell differentiation in testicular germ cell tumors in vitro and in vivo

    Blomberg Jensen, M., Jørgensen, A., Nielsen, J. E., Steinmeyer, A., Leffers, H., Juul, A. & Rajpert-De Meyts, E. 2012 In : Neoplasia. 14, 10, p. 952-63 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 2011
  36. Published

    Microdissection of gonadal tissues for gene expression analyses

    Jørgensen, A., Dalgaard, M. D. & Sonne, S. B. 1 Jan 2011 In : Methods in Molecular Biology. 755, p. 307-13 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2010
  38. Published
  39. Published

    Expression of prostaglandin synthases (pgds and pges) during zebrafish gonadal differentiation

    Jørgensen, A., Nielsen, J. E., Nielsen, B. F., Morthorst, J. E., Bjerregaard, P. & Leffers, H. 1 Sep 2010 In : Comparative Biochemistry and Physiology. Part A: Molecular & Integrative Physiology. 157, 1, p. 102-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published
  41. Published
  42. 2009
  43. Published

    TBT pollution and effects in molluscs at US Virgin Islands, Caribbean Sea

    Strand, J., Jørgensen, A. & Tairova, Z. May 2009 In : Environment International. 35, 4, p. 707-11 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Laser capture microdissection of gonads from juvenile zebrafish

    Jørgensen, A., Nielsen, J. E., Morthorst, J. E., Bjerregaard, P. & Leffers, H. 2009 In : Reproductive Biology and Endocrinology. 7, p. 97

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2008
  46. Published

    Biotransformation of polycyclic aromatic hydrocarbons in marine polychaetes

    Jørgensen, A., Giessing, A. M. B., Rasmussen, L. J. & Andersen, O. Mar 2008 In : Marine Environmental Research. 65, 2, p. 171-86 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Expression profiles for six zebrafish genes during gonadal sex differentiation

    Jørgensen, A., Morthorst, J. E., Andersen, O., Rasmussen, L. J. & Bjerregaard, P. 2008 In : Reproductive Biology and Endocrinology. 6, p. 25

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. 2007
  49. Published

    Identification and characterisation of an androgen receptor from zebrafish Danio rerio

    Jørgensen, A., Andersen, O., Bjerregaard, P. & Rasmussen, L. J. Nov 2007 In : Comparative Biochemistry and Physiology. Part C: Toxicology & Pharmacology. 146, 4, p. 561-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. 2005
  51. Published

    Biotransformation of the polycyclic aromatic hydrocarbon pyrene in the marine polychaete Nereis virens

    Jørgensen, A., Glessing, A. M. B., Rasmussen, L. J. & Andersen, O. Nov 2005 In : Environmental toxicology and chemistry / SETAC. 24, 11, p. 2796-805 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Characterisation of two novel CYP4 genes from the marine polychaete Nereis virens and their involvement in pyrene hydroxylase activity

    Jørgensen, A., Rasmussen, L. J. & Andersen, O. 28 Oct 2005 In : Biochemical and Biophysical Research Communications. 336, 3, p. 890-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. 2004
  54. Published

    Identification of two Nereis virens (Annelida: Polychaeta) cytochromes P450 and induction by xenobiotics

    Rewitz, K. F., Kjellerup, C., Jørgensen, A., Petersen, C. & Andersen, O. May 2004 In : Comparative Biochemistry and Physiology. Part C: Toxicology & Pharmacology. 138, 1, p. 89-96 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 30784239