Personal profile
Expertises
Clinical pharmacology; rational pharmacotherapy; clinical research; bile acid and glucose metabolism; therapeutic drug monitoring
Main research areas
My research activities are based on my daily work as a clinical pharmacologist and deal with, among other things, the treatment effect of drugs (rational pharmacotherapy) and concentration measurements of drugs in the blood.
I have previously conducted clinical experimental research in connection with my PhD thesis on human bile acid and sugar metabolism.
Current research
I am employed as a clinical associate professor within the specialty of clinical pharmacology at the Department of Clinical Medicine at the University of Copenhagen.
I act as co-supervisor for the PhD students Henriette H. Nerild, Mariam N. Carstensen and Jakob K. Hoe, who are conducting studies on bile acid metabolism, therapeutic drug monitoring (TDM) and specific drug therapy, respectively.
Potential conflicts of interest
My PhD project was supported by scintifically unrestricted funding from Sanofi A/S and research grants from the A.P. Møller Foundation for the Advancement of Medical Science, and the Danish Diabetes Academy.
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Collaborations and top research areas from the last five years
Research output
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Metabolic, enterohepatic and gut microbial effects of atorvastatin in healthy men
Thomasen, M., Misiakou, M.-A., Li, S. S., Rodriguez de Evgrafov, M. C., Lynggaard, M. B., Kårhus, M. L., Brønden, A., Kornholt, J., Chávez-Talavera, O., Tailleux, A., Staels, B., Descat, A., Hartmann, B., Wewer Albrechtsen, N. J., Rehfeld, J. F., Holst, J. J., Vilsbøll, T., Ellegaard, A.-M., Sommer, M. O. A. & Sonne, D. P. & 1 others, , Feb 2026, In: Endocrine Connections. 15, 3, e250721.Research output: Contribution to journal › Journal article › Research › peer-review
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Evaluation of antiseizure medication concentration ranges in blood samples using an automated big data approach
Nersesjan, M., Hoffmann-Lücke, E., Greibe, E., Aaslo, P. H., Bak, L. K., Pedersen, L. E., Fruekilde, P. B. N., Stark, A., Christensen, J., Brønden, A. & Larsen, J. B., Jun 2025, In: Epilepsia. 66, 6, p. 1888-1898 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Expression of bile acid receptors and transporters along the intestine of patients with type 2 diabetes and controls
Nerild, H. H., Gilliam-Vigh, H., Ellegaard, A.-M., Forman, J. L., Vilsbøll, T., Sonne, D. P., Brønden, A. & Knop, F. K., 1 Mar 2025, In: The Journal of clinical endocrinology and metabolism. 110, 3, p. e660-e666 dgae261.Research output: Contribution to journal › Journal article › Research › peer-review
4 Citations (Scopus) -
Increased gallbladder emptying and reduced GLP-1 response in pregnancy with and without gestational diabetes mellitus
Gether, I. M., Andersen, E. S., Foghsgaard, S., Ellegaard, A.-M., Kelstrup, L., Sonne, D. P., Brønden, A., Gillum, M. P., Holst, J. J., Hartmann, B., Rehfeld, J. F., Vilsbøll, T. & Knop, F. K., Feb 2025, In: Diabetes, Obesity and Metabolism. 27, 2, p. 697-709 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
Elucidating the glucose-lowering effect of the bile acid sequestrant sevelamer
Nerild, H. H., Brønden, A., Haddouchi, A. E., Ellegaard, A.-M., Hartmann, B., Rehfeld, J. F., Holst, J. J., Sonne, D. P., Vilsbøll, T. & Knop, F. K., Apr 2024, In: Diabetes, Obesity and Metabolism. 26, 4, p. 1252-1263 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
3 Citations (Scopus)