Research output per year
Research output per year
Personal profile
Expertises
Type 2 diabetes; clinical research; incretin physiology; bile acid metabolism
Main research areas
I conduct clinical experimental research on the role of bile acid physiology in the human metabolism, with a special focus on glucose metabolism.
Current research
I finished my PhD entitled “A gluco-metabolic perspective on the enterohepatic circulation of bile acids” in June 2017 and is currently holding a split position as a medical doctor (80%) and postdoc (20%).
I am assigned as a co-supervisor for the PhD students Christina Nexøe-Larsen, Henriette Holst and Pernille Sørensen in addition to the research year student Nina Hansen. These students are conducting various clinical experimental studies involving the link between bile acid physiology and glucose metabolism.
Potential conflicts of interest
My PhD project was supported by scintifically unrestricted funding from Sanofi A/S and research grants from the Danish Diabetes Academy supported by the Novo Nordisk Foundation and the A.P. Møller Foundation for the Advancement of Medical Science. I have received a lecture fee from AstraZeneca.
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Research output
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Liraglutide changes postprandial responses of gut hormones involved in the regulation of gallbladder motility
Nerild, H. H., Brønden, A., Gether, I. M., Hellmann, P. H., Baekdal, M., Gillum, M. P., Svenningsen, J. S., Hartmann, B., Rathor, N., Angelene, H., Rehfeld, J. F., Holst, J. J., Vilsbøll, T., Sonne, D. P. & Knop, F. K., Jun 2023, In: Diabetes, Obesity and Metabolism. 25, 6, p. 1632-1637 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of Meal Texture on Postprandial Glucose Excursions and Gut Hormones After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy
Hedbäck, N., Hindsø, M., Bojsen-Møller, K. N., Linddal, A. K., Jørgensen, N. B., Dirksen, C., Møller, A., Kristiansen, V. B., Hartmann, B., Holst, J. J., Svane, M. S. & Madsbad, S., 29 Apr 2022, In: Frontiers in nutrition. 9, p. 1-10 10 p., 889710.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
Enterohepatic, Gluco-metabolic, and Gut Microbial Characterization of Individuals With Bile Acid Malabsorption
Kårhus, M. L., Sonne, D. P., Thomasen, M., Ellegaard, A. M., Holst, J. J., Rehfeld, J. F., Chávez-Talavera, O., Tailleux, A., Staels, B., Nielsen, D. S., Krych, L., Dragsted, L. O., Vilsbøll, T., Bronden, A. & Knop, F. K., 3 Dec 2022, In: Elsevier. 1, 3, p. 299-312Research output: Contribution to journal › Journal article › Research › peer-review
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Safety and efficacy of liraglutide versus colesevelam for the treatment of bile acid diarrhoea: a randomised, double-blind, active-comparator, non-inferiority clinical trial
Kårhus, M. L., Brønden, A., Forman, J. L., Haaber, A., Knudsen, E., Langholz, E., Dragsted, L. O., Hansen, S. H., Krakauer, M., Vilsbøll, T., Sonne, D. P. & Knop, F. K., Oct 2022, In: The Lancet Gastroenterology and Hepatology. 7, 10, p. 922-931 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
6 Citations (Scopus) -
Liraglutide decreases postprandial fibroblast growth factor 19 and glucagon-like peptide 2, and increases postprandial cholecystokinin in individuals with obesity
Bronden, A., Nerild, H. H., Nexoe-Larsen, C. C., Hellmann, P. H., Baekdal, M., Gether, I. M., Gillum, M. P., Hartmann, B., Knudsen, L. B., Jacobsen, L. V., Rehfeld, J. F., Holst, J. J., Vilsboll, T., Sonne, D. P. & Knop, F. K., Sep 2021, p. 94-94. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review