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skeletal muscle; hypertrophy; atrophy; myogenesis; satellite cells; sarcopenia; muscle regeneration

Main research areas

The overall aim is to gain insight into mechanisms of skeletal muscle adaptation in elderly individuals. Models of injury and overload are employed to study the activity of muscle stem cells (satellite cells) and muscle extracellular matrix.

Current research

Investigations into potent influencing factors, such as changed levels of inflammation and loading, are designed with the goal of deepening our understanding of the ageing muscle. In addition to this, we are currently studying cross-talk between the muscle and its extracellular matrix, throughout the muscle as well as specifically at the myotendinous junction, in human models of regeneration and overload. This is being done in human studies in vivo and in vitro.

Potential conflicts of interest



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Collaborations and top research areas from the last five years

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