Personal profile
Brief presentation
Experienced leader with many years of management in the cutting-edge fields of cell therapy and gene editing (viral- and non-viral). Passionate about driving innovation and transforming healthcare through groundbreaking technologies (TIL-therapy, CAR-T therapy). Proven track record of guiding cross-functional teams, fostering collaboration, and successfully navigating complex regulatory landscapes. Committed to advancing the frontiers of science and delivering life-changing treatments to patients in need.
Main research areas
Research focus is in the area of molecular and cellular tumor immunology which includes both basic research and development of novel molecular immunotherapeutic strategies for treatment of cancer.
Current research
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Collaborations and top research areas from the last five years
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Safety and feasibility of blood-derived multiple antigen-specific endogenously derived T cells (MASE-T) for metastatic melanoma
Monberg, T. J., Tvingsholm, S. A., Svensson-Frej, M., Vestergaard, C., Ormhøj, M., Kjeldsen, J. W., Borch, T. H., Holmstroem, R. B., Jayashankar, N., Granhøj, J. S., Cordt, A. R., Larsen, S. K., Met, Ö., Hadrup, S. R. & Svane, I. M., Mar 2026, In: Immuno-oncology technology. 29, p. 101581 101581.Research output: Contribution to journal › Journal article › Research › peer-review
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Case Report: Severe HHV-6-related encephalitis following anti-CD19 CAR-T therapy with no evidence of HHV-6 reactivation in transduced CAR-T cells
Birk, N. M., Kielsen, K., Met, Ö., Haastrup, E. K., Hulen, T. M., Madsen, C., Barington, T., Nielsen, J., Schønning, K., Petersen, S. L. & Ifversen, M., 2025, In: Frontiers in Hematology. 4, 1628552.Research output: Contribution to journal › Journal article › Research › peer-review
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Harnessing Arginase-2-specific CD8+ T cells to target immunosuppressive Cutaneous T cell Lymphoma
Lisle, T. L., Weis-Banke, S. E., Ahmad, S. M., Holmström, M. O., Luu, T. V., Buus, T. B., Jessen, L. E., Dellgren, C., Barington, T., Met, Ö., Ødum, N. & Andersen, M. H., 10 Nov 2025, (E-pub ahead of print) In: British Journal of Dermatology.Research output: Contribution to journal › Journal article › Research › peer-review
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MerTK Signaling in Human Primary T cells Modulates Memory Potential and Improves Recall response
Rahbech, A., Kurzay, A., Fresnillo Saló, S., Seremet, T., Debets, R., Met, Ö., Peeters, M. J. W. & Straten, P. T., 14 Mar 2025, In: Journal of Leukocyte Biology. 117, 3, qiae226.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
Overcoming antigen loss in CAR T therapy with Vγ9Vδ2 CAR T-cells
Velasco Santiago, M., Aehnlich, P., Hulen, T. M., Jensen, K. M., Holmen Olofsson, G., Met & thor Straten, P., Jun 2025, In: Immuno-Oncology and Technology. 26, 101053.Research output: Contribution to journal › Journal article › Research › peer-review