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Tværgående enheder Rigshospitalet - a part of Copenhagen University Hospital

Tværgående enheder Rigshospitalet

Organisational unit: Centre

  1. 2021
  2. Published

    A screening method to spot biomarkers that may warn of serious events in a chronic disease - illustrated by cardiological CLARICOR trial data

    Winkel, P., Hilden, J., Jakobsen, J. C., Lindschou, J., Jensen, G. B., Kjøller, E., Sajadieh, A., Kastrup, J., Kolmos, H. J., Larsson, A., Ärnlöv, J., Bjerre, M. & Gluud, C., 26 Oct 2021, In: Clinical Chemistry and Laboratory Medicine. 59, 11, p. 1852-1860 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Internal bowel herniation through a peritoneal defect between the right fallopian tube and right ovarian vessels

    Dibbern, C. B., Bergstrand-Poulsen, E., Farooqui, W. & Penninga, L., 7 Oct 2021, In: BMJ Case Reports . 14, 10

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. E-pub ahead of print

    Combining meta-epidemiological study datasets on commercial funding of randomised clinical trials: database, methods, and descriptive results of the COMFIT study

    COMFIT consortium, 23 Sep 2021, (E-pub ahead of print) In: Research Synthesis Methods.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published
  6. Published

    Repolarization and ventricular arrhythmia during targeted temperature management post cardiac arrest

    Thomsen, J. H., Hassager, C., Erlinge, D., Nielsen, N., Lindholm, M. G., Bro-Jeppesen, J., Grand, J., Pehrson, S., Graff, C., Køber, L. V. & Kjaergaard, J., Sep 2021, In: Resuscitation. 166, p. 74-82 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The effects of adding quinolones to beta-lactam antibiotics for sepsis

    Korang, S. K., Maagaard, M., Feinberg, J. B., Perner, A., Gluud, C. & Jakobsen, J. C., Sep 2021, In: Acta Anaesthesiologica Scandinavica. 65, 8, p. 1023-1032 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  8. E-pub ahead of print

    Oxygenation targets in ICU patients with COVID-19: a post-hoc sub-group analysis of the HOT-ICU trial

    Rasmussen, B. S., Klitgaard, T. L., Perner, A., Brand, B. A., Hildebrandt, T., Siegemund, M., Hollinger, A., Aagaard, S. R., Bestle, M. H., Marcussen, K. V., Brøchner, A. C., Sølling, C. G., Poulsen, L. M., Laake, J. H., Aslam, T. N., Bäcklund, M., Okkonen, M., Morgan, M., Sharman, M., Lange, T., Wetterslev, J. & Schjørring, O. L., 23 Aug 2021, (E-pub ahead of print) In: Acta Anaesthesiologica Scandinavica.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published
  10. Published

    Methylphenidate for ADHD rejected from the WHO Essential Medicines List due to uncertainties in benefit-harm profile

    Storebø, O. J. & Gluud, C., 1 Aug 2021, In: BMJ Evidence-Based Medicine. 26, 4, p. 172-175 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published
  12. Published

    Tranexamic Acid for Prevention of Hematoma Expansion in Intracerebral Hemorrhage Patients With or Without Spot Sign

    Ovesen, C., Jakobsen, J. C., Gluud, C., Steiner, T., Law, Z., Flaherty, K., Dineen, R. A., Christensen, L. M., Overgaard, K., Rasmussen, R. S., Bath, P. M., Sprigg, N., Christensen, H. & TICH-2 Investigators, Aug 2021, In: Stroke. 52, 8, p. 2629-2636 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Central data monitoring in the multicentre randomised SafeBoosC-III trial - a pragmatic approach

    Olsen, M. H., Hansen, M. L., Safi, S., Jakobsen, J. C., Greisen, G., Gluud, C. & SafeBoosC-III Trial Group, 31 Jul 2021, In: BMC Medical Research Methodology. 21, 1, p. 160 160.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published
  15. Published
  16. Published

    A new tool to assess Clinical Diversity In Meta-analyses (CDIM) of interventions

    Barbateskovic, M., Koster, T. M., Eck, R. J., Maagaard, M., Afshari, A., Blokzijl, F., Cronhjort, M., Dieperink, W., Fabritius, M. L., Feinberg, J., French, C., Gareb, B., Geisler, A., Granholm, A., Hiemstra, B., Hu, R., Imberger, G., Jensen, B. T., Jonsson, A. B., Karam, O., Kong, D. Z., Korang, S. K., Koster, G., Lai, B., Liang, N., Lundstrøm, L. H., Marker, S., Meyhoff, T., Nielsen, E. E., Nørskov, A. K., Munch, M. W., Risom, E. C., Rygård, S. L., Safi, S., Sethi, N., Sjövall, F., Lauridsen, S. V., van Bakelen, N., Volbeda, M., van der Horst, I., Gluud, C., Perner, A., Møller, M. H., Keus, F. & Wetterslev, J., Jul 2021, In: Journal of Clinical Epidemiology. 135, p. 29-41 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest

    Dankiewicz, J., Cronberg, T., Lilja, G., Jakobsen, J. C., Levin, H., Ullén, S., Rylander, C., Wise, M. P., Oddo, M., Cariou, A., Bělohlávek, J., Hovdenes, J., Saxena, M., Kirkegaard, H., Young, P. J., Pelosi, P., Storm, C., Taccone, F. S., Joannidis, M., Callaway, C., Eastwood, G. M., Morgan, M. P. G., Nordberg, P., Erlinge, D., Nichol, A. D., Chew, M. S., Hollenberg, J., Thomas, M., Bewley, J., Sweet, K., Grejs, A. M., Christensen, S., Haenggi, M., Levis, A., Lundin, A., Düring, J., Schmidbauer, S., Keeble, T. R., Karamasis, G. V., Schrag, C., Faessler, E., Smid, O., Otáhal, M., Maggiorini, M., Wendel Garcia, P. D., Jaubert, P., Cole, J. M., Solar, M., Borgquist, O., Nielsen, N. & TTM2 Trial Investigators, 17 Jun 2021, In: The New England journal of medicine. 384, 24, p. 2283-2294 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. E-pub ahead of print

    Low-dose hydrocortisone in patients with COVID-19 and severe hypoxia: the COVID STEROID randomised, placebo-controlled trial

    Munch, M. W., Meyhoff, T. S., Helleberg, M., Kjaer, M-B. N., Granholm, A., Hjortsø, C. J. S., Jensen, T. S., Møller, M. H., Hjortrup, P. B., Wetterslev, M., Vesterlund, G. K., Russell, L., Jørgensen, V. L., Tjelle Kristiansen, K., Benfield, T., Ulrik, C. S., Andreasen, A. S., Bestle, M. H., Poulsen, L. M., Hildebrandt, T., Knudsen, L. S., Møller, A., Sølling, C. G., Brøchner, A. C., Rasmussen, B. S., Nielsen, H., Christensen, S., Strøm, T., Cronhjort, M., Wahlin, R. R., Jakob, S. M., Cioccari, L., Venkatesh, B., Hammond, N., Jha, V., Myatra, S. N., Jensen, M. Q., Leistner, J. W., Mikkelsen, V. S., Svenningsen, J. S., Laursen, S. B., Hatley, E. V., Kristensen, C. M., Al-Alak, A., Clapp, E., Jonassen, T. B., Bjerregaard, C. L., Østerby, N. C. H., Jespersen, M. M., Abou-Kassem, D., Lassen, M. L., Zaabalawi, R., Daoud, M. M., Abdi, S., Meier, N., la Cour, K., Derby, C. B., Damlund, B. R., Laigaard, J., Andersen, L. L., Mikkelsen, J., Jensen, J. L. S., Rasmussen, A. H., Arnerlöv, E., Lykke, M., Holst-Hansen, M. Z. B., Tøstesen, B. W., Schwab, J., Madsen, E. K., Gluud, C., Lange, T. & Perner, A., 17 Jun 2021, (E-pub ahead of print) In: Acta Anaesthesiologica Scandinavica.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published
  20. E-pub ahead of print
  21. Published

    Assessment of assumptions of statistical analysis methods in randomised clinical trials: the what and how

    Nørskov, A. K., Lange, T., Nielsen, E. E., Gluud, C., Winkel, P., Beyersmann, J., de Uña-Álvarez, J., Torri, V., Billot, L., Putter, H., Wetterslev, J., Thabane, L. & Jakobsen, J. C., Jun 2021, In: BMJ Evidence-Based Medicine. 26, 3, p. 121-126 6 p., 111268.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Blinding in randomised clinical trials of psychological interventions: a retrospective study of published trial reports

    Juul, S., Gluud, C., Simonsen, S., Frandsen, F. W., Kirsch, I. & Jakobsen, J. C., Jun 2021, In: BMJ Evidence-Based Medicine. 26, 3, p. 109

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Considerations on the strengths and limitations of using disease-related mortality as an outcome in clinical research

    Jakobsen, J. C., Wetterslev, J. & Gluud, C., Jun 2021, In: BMJ Evidence-Based Medicine. 26, 3, p. 127-130 4 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  24. Published
  25. E-pub ahead of print

    Ongoing and future COVID-19 vaccine clinical trials: challenges and opportunities

    Dal-Ré, R., Bekker, L-G., Gluud, C., Holm, S., Jha, V., Poland, G. A., Rosendaal, F. R., Schwarzer-Daum, B., Sevene, E., Tinto, H., Voo, T. C. & Sreeharan, N., 18 May 2021, (E-pub ahead of print) In: The Lancet Infectious Diseases.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Antibiotic regimens for early-onset neonatal sepsis

    Korang, S. K., Safi, S., Nava, C., Gordon, A., Gupta, M., Greisen, G., Lausten-Thomsen, U. & Jakobsen, J. C., 17 May 2021, In: Cochrane Database of Systematic Reviews. 5, 5, p. CD013837

    Research output: Contribution to journalReviewResearchpeer-review

  27. Published

    Antibiotic regimens for late-onset neonatal sepsis

    Korang, S. K., Safi, S., Nava, C., Greisen, G., Gupta, M., Lausten-Thomsen, U. & Jakobsen, J. C., 8 May 2021, In: Cochrane Database of Systematic Reviews. 5, 5, p. CD013836

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Exercise-based cardiac rehabilitation for adults after heart valve surgery

    Abraham, L. N., Sibilitz, K. L., Berg, S. K., Tang, L. H., Risom, S. S., Lindschou, J., Taylor, R. S., Borregaard, B. & Zwisler, A-D., 7 May 2021, In: Cochrane Database of Systematic Reviews. 2021, 5, p. CD010876 CD010876.

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    Carotid endarterectomy with patch angioplasty versus primary closure in patients with symptomatic and significant stenosis: a systematic review with meta-analyses and trial sequential analysis of randomized clinical trials

    Marsman, M. S., Wetterslev, J., Jahrome, A. K., Gluud, C., Moll, F. L., Keus, F. & Koning, G. G., 6 May 2021, In: Systematic Reviews. 10, 1, p. 139 139.

    Research output: Contribution to journalReviewResearchpeer-review

  30. Published

    Higher vs. Lower Doses of Dexamethasone in Patients with COVID-19 and Severe Hypoxia (COVID STEROID 2) trial: protocol for a secondary Bayesian analysis

    Granholm, A., Munch, M. W., Myatra, S. N., Vijayaraghavan, B. K. T., Cronhjort, M., Wahlin, R. R., Jakob, S. M., Cioccari, L., Kjaer, M-B. N., Vesterlund, G. K., Meyhoff, T. S., Helleberg, M., Møller, M. H., Benfield, T., Venkatesh, B., Hammond, N., Micallef, S., Bassi, A., John, O., Jha, V., Tjelle Kristiansen, K., Ulrik, C. S., Jørgensen, V. L., Smitt, M., Bestle, M. H., Andreasen, A. S., Poulsen, L. M., Rasmussen, B. S., Brøchner, A. C., Strøm, T., Møller, A., Khan, M. S., Padmanaban, A., Vasishtha Divatia, J., Saseedharan, S., Borawake, K., Kapadia, F., Dixit, S., Chawla, R., Shukla, U., Amin, P., Chew, M. S., Gluud, C., Lange, T. & Perner, A., May 2021, In: Acta Anaesthesiologica Scandinavica. 65, 5, p. 702-710 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published
  32. Published

    The clinical effects of cerebral near-infrared spectroscopy monitoring (NIRS) versus no monitoring: a protocol for a systematic review with meta-analysis and trial sequential analysis

    Hansen, M. L., Hyttel-Sørensen, S., Jakobsen, J. C., Gluud, C., Kooi, E. M. W., Mintzer, J., de Boode, W. P., Fumagalli, M., Alarcon, A., Alderliesten, T. & Greisen, G., 16 Apr 2021, In: Systematic Reviews. 10, 1, p. 111 111.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published
  34. Published

    Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure

    Schjørring, O. L., Klitgaard, T. L., Perner, A., Wetterslev, J., Lange, T., Siegemund, M., Bäcklund, M., Keus, F., Laake, J. H., Morgan, M., Thormar, K. M., Rosborg, S. A., Bisgaard, J., Erntgaard, A. E. S., Lynnerup, A-S. H., Pedersen, R. L., Crescioli, E., Gielstrup, T. C., Behzadi, M. T., Poulsen, L. M., Estrup, S., Laigaard, J. P., Andersen, C., Mortensen, C. B., Brand, B. A., White, J., Jarnvig, I-L., Møller, M. H., Quist, L., Bestle, M. H., Schønemann-Lund, M., Kamper, M. K., Hindborg, M., Hollinger, A., Gebhard, C. E., Zellweger, N., Meyhoff, C. S., Hjort, M., Bech, L. K., Grøfte, T., Bundgaard, H., Østergaard, L. H. M., Thyø, M. A., Hildebrandt, T., Uslu, B., Sølling, C. G., Møller-Nielsen, N., Gøttrup Pedersen, U., Andreasen, A. S., Engstrøm, J., Kjær, M-B. N., HOT-ICU Investigators, Bertelsen Jensen, D., Mørk Sørensen, K., Sprogøe Rasmussen, P., Rovsing Hjortdal, A., Reiter, N., Clausen, N. E., Hein, L., Ibsen, M. & Sigurðsson, S. Þ., 8 Apr 2021, In: The New England journal of medicine. 384, 14, p. 1301-1311 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Lenient rate control versus strict rate control for atrial fibrillation: a protocol for the Danish Atrial Fibrillation (DanAF) randomised clinical trial

    Feinberg, J. B., Olsen, M. H., Brandes, A., Raymond, L., Nielsen, W. B., Nielsen, E. E., Stensgaard-Hansen, F., Dixen, U., Pedersen, O. D., Gang, U. J. O., Gluud, C. & Jakobsen, J. C., 31 Mar 2021, In: BMJ Open. 11, 3, p. 1-9 9 p., 044744.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Conflict of Interest Policies at Medical Schools and Teaching Hospitals: A Systematic Review of Cross-sectional Studies

    Fabbri, A., Hone, K. R., Hróbjartsson, A. & Lundh, A., 3 Mar 2021, In: International Journal of Health Policy and Management.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published
  38. Published

    Effect of low vs. high haemoglobin transfusion trigger on cardiac output in patients undergoing elective vascular surgery: Post-hoc analysis of a randomized trial

    Møller, A., Wetterslev, J., Shahidi, S., Hellemann, D., Secher, N. H., Pedersen, O. B., Marcussen, K. V., Ramsing, B. G. U., Mortensen, A. & Nielsen, H. B., Mar 2021, In: Acta Anaesthesiologica Scandinavica. 65, 3, p. 302-312 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Interventions for treatment of COVID-19: Second edition of a living systematic review with meta-analyses and trial sequential analyses (The LIVING Project)

    Juul, S., Nielsen, E. E., Feinberg, J., Siddiqui, F., Jørgensen, C. K., Barot, E., Holgersson, J., Nielsen, N., Bentzer, P., Veroniki, A. A., Thabane, L., Bu, F., Klingenberg, S., Gluud, C. & Jakobsen, J. C., Mar 2021, In: PLoS One. 16, 3, p. e0248132 e0248132.

    Research output: Contribution to journalReviewResearchpeer-review

  40. Published
  41. Published

    Antibiotics for secondary prevention of coronary heart disease

    Sethi, N. J., Safi, S., Korang, S. K., Hróbjartsson, A., Skoog, M., Gluud, C. & Jakobsen, J. C., 23 Feb 2021, In: Cochrane Database of Systematic Reviews. 2021, 2, p. CD003610 CD003610.

    Research output: Contribution to journalReviewResearchpeer-review

  42. Published
  43. Published

    Ethical and Scientific Considerations Regarding the Early Approval and Deployment of a COVID-19 Vaccine

    Dal-Ré, R., Caplan, A. L., Gluud, C. & Porcher, R., 1 Feb 2021, In: Annals of Internal Medicine. 174, 2, p. 258-260 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  44. Published

    Clinical relevance assessment of animal preclinical research (RAA) tool: development and explanation

    Gurusamy, K. S., Moher, D., Loizidou, M., Ahmed, I., Avey, M. T., Barron, C. C., Davidson, B., Dwek, M., Gluud, C., Jell, G., Katakam, K., Montroy, J., McHugh, T. D., Osborne, N. J., Ritskes-Hoitinga, M., van Laarhoven, K., Vollert, J. & Lalu, M., 27 Jan 2021, In: PeerJ. 9, p. e10673 10673.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published
  46. Published

    Higher vs Lower Oxygenation Strategies in Acutely Ill Adults: A Systematic Review With Meta-Analysis and Trial Sequential Analysis

    Barbateskovic, M., Schjørring, O. L., Krauss, S. R., Meyhoff, C. S., Jakobsen, J. J., Rasmussen, B. S., Perner, A. & Wetterslev, J., Jan 2021, In: Chest. 159, 1, p. 154-173 20 p.

    Research output: Contribution to journalReviewResearchpeer-review

  47. Published

    Risk factors for long-term cognitive impairment in ICU survivors: A multicenter, prospective cohort study

    Collet, M. O., Egerod, I., Thomsen, T., Wetterslev, J., Lange, T., Ebdrup, B. H. & Perner, A., Jan 2021, In: Acta Anaesthesiologica Scandinavica. 65, 1, p. 92-99 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Antibiotic regimens for early‐onset neonatal sepsis (Protocol)

    Korang, S. K., Safi, S., Gupta, M., Gordon, A., Greisen, G., Lausten-Thomsen, U. & Jakobsen, J. C., 2021, In: Cochrane Database of Systematic Reviews. p. CD013837

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Antibiotic regimens for late‐onset neonatal sepsis (Protocol)

    Korang, S. K., Safi, S., Gupta, M., Greisen, G., Lausten-Thomsen, U. & Jakobsen, J. C., 2021, In: Cochrane Database of Systematic Reviews. p. CD013836

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Antibiotics for hospital‐acquired pneumonia in neonates and children (Protocol)

    Korang, S. K., Nava, C., Nygaard, U. & Jakobsen, J. C., 2021, In: Cochrane Database of Systematic Reviews. p. CD013864

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. E-pub ahead of print

    Early specialised palliative care: interventions, symptoms, problems

    Skjoedt, N., Johnsen, A. T., Sjøgren, P., Neergaard, M. A., Damkier, A., Gluud, C., Lindschou, J., Fayers, P., Higginson, I. J., Strömgren, A. S. & Groenvold, M., 2021, (E-pub ahead of print) In: BMJ Supportive and Palliative Care.

    Research output: Contribution to journalJournal articleResearchpeer-review

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