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Clinical Experimental Research, Department of - a part of Copenhagen University Hospital

Clinical Experimental Research, Department of

Organisational unit: Department

  1. 2021
  2. Published
  3. 2020
  4. E-pub ahead of print

    A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19

    ACTIV-3/TICO LY-CoV555 Study Group, 22 Dec 2020, In : The New England journal of medicine.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. E-pub ahead of print
  6. Published

    Estrogen receptors α, β and GPER in the CNS and trigeminal system - molecular and functional aspects

    Warfvinge, K., Krause, D. N., Maddahi, A., Edvinsson, J. C. A., Edvinsson, L. & Haanes, K. A., 10 Nov 2020, In : The Journal of Headache and Pain Online. 21, 1, p. 131

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published
  8. Published
  9. Published

    Expression of the CGRP Family of Neuropeptides and their Receptors in the Trigeminal Ganglion

    Edvinsson, L., Grell, A-S. & Warfvinge, K., Jun 2020, In : Journal of Molecular Neuroscience. 70, 6, p. 930-944 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published
  11. Published

    CGRP in rat mesenteric artery and vein - receptor expression, CGRP presence and potential roles

    Le, T. L., Jagd Grell, A-S., Sheykhzade, M., Warfvinge, K., Edvinsson, L. & Sams, A., 15 May 2020, In : European Journal of Pharmacology. 875, p. 173033

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Cellular distribution of PACAP-38 and PACAP receptors in the rat brain: Relation to migraine activated regions

    Warfvinge, K. & Edvinsson, L., May 2020, In : Cephalalgia : an international journal of headache. 40, 6, p. 527-542 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published
  14. Published

    Understanding side-effects of anti-CGRP and anti-CGRP receptor antibodies

    Haanes, K. A., Edvinsson, L. & Sams, A., 16 Mar 2020, In : The Journal of Headache and Pain Online. 21, 1, p. 26

    Research output: Contribution to journalLetterResearchpeer-review

  15. Published
  16. Published

    The role of purinergic P2Y12 and P2Y13 receptors in ADPβS-induced inhibition of the cardioaccelerator sympathetic drive in pithed rats

    Villanueva-Castillo, B., Rivera-Mancilla, E., Haanes, K. A., MaassenVanDenBrink, A. & Villalón, C. M., Mar 2020, In : Purinergic Signalling. 16, 1, p. 73-84 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Hyperpolarization through ATP-sensitive potassium channels; relevance to migraine pathology

    Haanes, K. A. & Edvinsson, L., 1 Feb 2020, In : Brain : a journal of neurology. 143, 2, p. e13

    Research output: Contribution to journalLetterResearchpeer-review

  18. Published

    Calcitonin Gene-Related Peptide (CGRP) and Cluster Headache

    Carmine Belin, A., Ran, C. & Edvinsson, L., 6 Jan 2020, In : Brain Sciences. 10, 1, p. 30 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published
  20. Published

    Fluorescent Analogues of Human α-Calcitonin Gene-Related Peptide with Potent Vasodilator Activity

    Zhu, J., Pedersen, M. D., Ahmed, L. S., Abdolalizadeh, B., Grell, A-S., Berg, J. O., Thulstrup, P. W., Franzyk, H., Edvinsson, L., Sams, A., Sheykhzade, M. & Hansen, P. R., 2020, In : International Journal of Molecular Sciences. 21, 4, p. E1343 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Local endothelial DNA repair deficiency causes aging-resembling endothelial-specific dysfunction

    Bautista-Niño, P. K., Portilla-Fernandez, E., Rubio-Beltrán, E., van der Linden, J. J., de Vries, R., van Veghel, R., de Boer, M., Durik, M., Ridwan, Y., Brandt, R., Essers, J., Menzies, R. I., Thomas, R., de Bruin, A., Duncker, D. J., van Beusekom, H. M. M., Ghanbari, M., Hoeijmakers, J. H. J., Sedlacek, R., Touyz, R. M., Montezano, A. C., van der Pluijm, I., Danser, A. H. J., Haanes, K. A. & Roks, A. J. M., 2020, In : Clinical science (London, England : 1979). 134, 7, p. 727-746 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The distribution of oxytocin and the oxytocin receptor in rat brain: relation to regions active in migraine

    Warfvinge, K., Krause, D. & Edvinsson, L., 2020, In : The Journal of Headache and Pain Online. 21, 1, p. 10 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The effects of CGRP in vascular tissue - Classical vasodilation, shadowed effects and systemic dilemmas

    Sohn, I., Sheykhzade, M., Edvinsson, L. & Sams, A., 2020, In : European Journal of Pharmacology. 881, p. 173205 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    The fifth cranial nerve in headaches

    Edvinsson, J. C. A., Viganò, A., Alekseeva, A., Alieva, E., Arruda, R., De Luca, C., D'Ettore, N., Frattale, I., Kurnukhina, M., Macerola, N., Malenkova, E., Maiorova, M., Novikova, A., Řehulka, P., Rapaccini, V., Roshchina, O., Vanderschueren, G., Zvaune, L., Andreou, A. P., Haanes, K. A. & European Headache Federation School of Advanced Studies (EHF-SAS), 2020, In : The Journal of Headache and Pain Online. 21, 1, p. 65

    Research output: Contribution to journalReviewResearchpeer-review

  25. 2019
  26. Published
  27. Published

    C-fibers may modulate adjacent Aδ-fibers through axon-axon CGRP signaling at nodes of Ranvier in the trigeminal system

    Edvinsson, J. C. A., Warfvinge, K., Krause, D. N., Blixt, F. W., Sheykhzade, M., Edvinsson, L. & Haanes, K. A., 12 Nov 2019, In : The Journal of Headache and Pain Online. 20, 1, p. 105 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The Presence of Calcitonin Gene-Related Peptide and Its Receptors in Rat, Pig and Human Brain: Species Differences in Calcitonin Gene-Related Peptide Pharmacology

    Warfvinge, K., Edvinsson, L., Pickering, D. S. & Sheykhzade, M., 1 Nov 2019, In : Pharmacology. 104, 5-6, p. 332-341 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Copeptin, a surrogate marker for arginine vasopressin secretion, is positively associated with glucagon

    Asferg, C. L., Andersen, U. B., Linneberg, A., Goetze, J. P., Holst, J. J. & Jeppesen, J. L., Nov 2019, In : Diabetic Medicine. 36, 11, p. 1408-1411 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Exploration of physiological and pathophysiological implications of miRNA-143 and miRNA-145 in cerebral arteries

    Christensen, S. T., Johansson, S. E., Warfvinge, K., Braun, T., Boettger, T., Edvinsson, L. & Haanes, K. A., Nov 2019, In : Journal of Cardiovascular Pharmacology. 74, 5, p. 409-419

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Non-eosinophilic severe exacerbations of COPD: what about antibiotics? - Authors' reply

    Sivapalan, P. & Jensen, J. U., Nov 2019, In : The Lancet Respiratory Medicine. 7, 11, p. e34

    Research output: Contribution to journalComment/debateResearchpeer-review

  32. Published

    Regional and socioeconomic variation in survival of melanoma patients in Denmark

    Steding-Jessen, M., Engberg, H., Øster, I., Jensen, J. W., Hölmich, L. R. & Møller, H., Nov 2019, In : Danish Medical Journal. 66, 11, p. A5572

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Exploration of purinergic receptors as potential anti-migraine targets using established pre-clinical migraine models

    Haanes, K. A., Labastida-Ramírez, A., Blixt, F. W., Rubio-Beltrán, E., Dirven, C. M., Danser, A. H., Edvinsson, L. & MaassenVanDenBrink, A., Oct 2019, In : Cephalalgia : an international journal of headache. 39, 11, p. 1421-1434 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published
  35. Published

    Does inflammation have a role in migraine?

    Edvinsson, L., Haanes, K. A. & Warfvinge, K., 1 Aug 2019, In : Nature reviews. Neurology. 15, 8, p. 483-490 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  36. Published

    Board Walk - July 2019

    Edvinsson, L., 1 Jul 2019, In : Cephalalgia : an international journal of headache. 39, 8, p. 1067-1068 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  37. Published

    Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

    CHD Exome+ Consortium, 1 Mar 2019, In : Nature Genetics. 51, 3, p. 452-469 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity

    Dallner, O. S., Marinis, J. M., Lu, Y-H., Birsoy, K., Werner, E., Fayzikhodjaeva, G., Dill, B. D., Molina, H., Moscati, A., Kutalik, Z., Marques-Vidal, P., Kilpeläinen, T. O., Grarup, N., Linneberg, A., Zhang, Y., Vaughan, R., Loos, R. J. F., Lazar, M. A. & Friedman, J. M., Mar 2019, In : Nature Medicine. 25, 3, p. 507-516 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Sex-Specific Epidemiology of Heart Failure Risk and Mortality in Europe: Results From the BiomarCaRE Consortium

    BiomarCaRE Consortium, Mar 2019, In : JACC. Heart failure. 7, 3, p. 204-213 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis

    Skaaby, T., Kilpeläinen, T. O., Taylor, A. E., Mahendran, Y., Wong, A., Ahluwalia, T. S., Paternoster, L., Trompet, S., Stott, D. J., Flexeder, C., Zhou, A., Brusselle, G., Sajjad, A., Lahousse, L., Tiemeier, H., Have, C. T., Thuesen, B. H., Kårhus, L. L., Møllehave, L. T., Leth-Møller, K. B., Shabanzadeh, D. M., Gonzalez-Quintela, A., Power, C., Hyppönen, E., Kuh, D., Hardy, R., Meitinger, T., Jukema, J. W., Völker, U., Nauck, M., Völzke, H., Friedrich, N., Bonten, T. N., Noordam, R., Mook-Kanamori, D. O., Tolstrup, J. S., Taube, C., Peters, A., Grallert, H., Strauch, K., Schulz, H., Grarup, N., Hansen, T., Pedersen, O., Burgess, S., Munafò, M. R. & Linneberg, A., 1 Feb 2019, In : Addiction. 114, 2, p. 216-225 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

    Kraja, A. T., Liu, C., Fetterman, J. L., Graff, M., Have, C. T., Gu, C., Yanek, L. R., Feitosa, M. F., Arking, D. E., Chasman, D. I., Young, K., Ligthart, S., Hill, W. D., Weiss, S., Luan, J., Giulianini, F., Li-Gao, R., Hartwig, F. P., Lin, S. J., Wang, L., Richardson, T. G., Yao, J., Fernandez, E. P., Ghanbari, M., Wojczynski, M. K., Lee, W-J., Argos, M., Armasu, S. M., Barve, R. A., Ryan, K. A., An, P., Baranski, T. J., Bielinski, S. J., Bowden, D. W., Broeckel, U., Christensen, K., Chu, A. Y., Corley, J., Cox, S. R., Uitterlinden, A. G., Rivadeneira, F., Cropp, C. D., Daw, E. W., van Heemst, D., de Las Fuentes, L., Gao, H., Tzoulaki, I., Ahluwalia, T. S., de Mutsert, R., Emery, L. S., Erzurumluoglu, A. M., Perry, J. A., Fu, M., Forouhi, N. G., Gu, Z., Hai, Y., Harris, S. E., Hemani, G., Hunt, S. C., Irvin, M. R., Jonsson, A. E., Justice, A. E., Kerrison, N. D., Larson, N. B., Lin, K-H., Love-Gregory, L. D., Mathias, R. A., Lee, J. H., Nauck, M., Noordam, R., Ong, K. K., Pankow, J., Patki, A., Pattie, A., Petersmann, A., Qi, Q., Ribel-Madsen, R., Rohde, R., Sandow, K., Schnurr, T. M., Sofer, T., Starr, J. M., Taylor, A. M., Teumer, A., Timpson, N. J., de Haan, H. G., Wang, Y., Weeke, P. E., Williams, C., Wu, H., Yang, W., Zeng, D., Witte, D. R., Weir, B. S., Wareham, N. J., Vestergaard, H., Turner, S. T., Torp-Pedersen, C., Stergiakouli, E., Sheu, W. H-H., Rosendaal, F. R., Ikram, M. A., Franco, O. H., Ridker, P. M., Perls, T. T., Pedersen, O., Nohr, E. A., Newman, A. B., Linneberg, A., Langenberg, C., Kilpeläinen, T. O., Kardia, S. L. R., Jørgensen, M. E., Jørgensen, T., Sørensen, T. I. A., Homuth, G., Hansen, T., Goodarzi, M. O., Deary, I. J., Christensen, C., Chen, Y-D. I., Chakravarti, A., Brandslund, I., Bonnelykke, K., Taylor, K. D., Wilson, J. G., Rodriguez, S., Davies, G., Horta, B. L., Thyagarajan, B., Rao, D. C., Grarup, N., Davila-Roman, V. G., Hudson, G., Guo, X., Arnett, D. K., Hayward, C., Vaidya, D., Mook-Kanamori, D. O., Tiwari, H. K., Levy, D., Loos, R. J. F., Dehghan, A., Elliott, P., Malik, A. N., Scott, R. A., Becker, D. M., de Andrade, M., Province, M. A., Meigs, J. B., Rotter, J. I. & North, K. E., 3 Jan 2019, In : American Journal of Human Genetics. 104, 1, p. 112-138 27 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Increased frequency of rare missense PPP1R3B variants among Danish patients with type 2 diabetes

    Niazi, R. K., Sun, J., Have, C. T., Hollensted, M., Linneberg, A., Pedersen, O., Nielsen, J. S., Rungby, J., Grarup, N., Hansen, T. & Gjesing, A. P., 1 Jan 2019, In : PLoS One. 14, 1, p. e0210114 e0210114.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published
  44. Published

    Synergistic effects of a cremophor EL drug delivery system and its U0126 cargo in an ex vivo model

    Christensen, S. T., Grell, A. S., Johansson, S. E., Andersson, C. M., Edvinsson, L. & Haanes, K. A., 1 Jan 2019, In : Drug Delivery . 26, 1, p. 680-688 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial

    Roager, H. M., Vogt, J. K., Kristensen, M., Hansen, L. B. S., Ibrügger, S., Mærkedahl, R. B., Bahl, M. I., Lind, M. V., Nielsen, R. L., Frøkiær, H., Gøbel, R. J., Landberg, R., Ross, A. B., Brix, S., Holck, J., Meyer, A. S., Sparholt, M. H., Christensen, A. F., Carvalho, V., Holst, J. J., Rumessen, J. J., Linneberg, A., Sicheritz-Pontén, T., Dalgaard, M. D., Blennow, A., Frandsen, H. L., Villas-Bôas, S., Kristiansen, K., Vestergaard, H., Hansen, T., Ekstrøm, C. T., Ritz, C., Nielsen, H. B., Pedersen, O. B., Gupta, R., Lauritzen, L. & Licht, T. R., 1 Jan 2019, In : Gut. 68, 1, p. 83-93 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Genetic determinants of blood pressure traits are associated with carotid arterial thickening and plaque formation in patients with type 2 diabetes

    CIMT Trial Group 10, Jan 2019, In : Diabetes and Vascular Disease Research. 16, 1, p. 13-21 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published
  48. Published

    Artemin and an Artemin-Derived Peptide, Artefin, Induce Neuronal Survival, and Differentiation Through Ret and NCAM

    Ilieva, M., Nielsen, J., Korshunova, I., Gotfryd, K., Bock, E., Pankratova, S. & Michel, T. M., 2019, In : Frontiers in Molecular Neuroscience. 12, p. 47

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Cross-sectional analysis of sleep hours and quality with sex hormones in men

    Ruge, M., Skaaby, T., Andersson, A-M. & Linneberg, A., 2019, In : Endocrine Connections. 8, 2, p. 141-149 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Distribution of CGRP and CGRP receptor components in the rat brain

    Warfvinge, K. & Edvinsson, L., 2019, In : Cephalalgia : an international journal of headache. 39, 3, p. 342-353 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published
  52. Published

    Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

    Broad Genomics Platform, 2019, In : Nature. 570, 7759, p. 71-76 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published
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