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Clinical Biochemistry - a part of Copenhagen University Hospital
  1. 2022
  2. Published
  3. Published

    Common variants in breast cancer risk loci predispose to distinct tumor subtypes

    kConFab/AOCS Investigators, NBCS Collaborators & ABCTB Investigators, Dec 2022, In: Breast Cancer Research. 24, 1, 2.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Gene–gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer

    Rosenberger, A., Muttray, N., Hung, R. J., Christiani, D. C., Caporaso, N. E., Liu, G., Bojesen, S. E., Le Marchand, L., Albanes, D., Aldrich, M. C., Tardon, A., Fernández-Tardón, G., Rennert, G., Field, J. K., Davies, M. P. A., Liloglou, T., Kiemeney, L. A., Lazarus, P., Wendel, B., Haugen, A. & 21 others, Zienolddiny, S., Lam, S., Schabath, M. B., Andrew, A. S., Duell, E. J., Arnold, S. M., Goodman, G. E., Chen, C., Doherty, J. A., Taylor, F., Cox, A., Woll, P. J., Risch, A., Muley, T. R., Johansson, M., Brennan, P., Landi, M. T., Shete, S. S., Amos, C. I., Bickeböller, H. & The INTEGRAL-ILCCO Consortium, Dec 2022, In: European Journal of Medical Research. 27, 1, 14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    I am hiQ—a novel pair of accuracy indices for imputed genotypes

    Rosenberger, A., Tozzi, V., Bickeböller, H. & The INTEGRAL-ILCCO Consortium, Dec 2022, In: BMC Bioinformatics. 23, 1, 50.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Severe α1-antitrypsin deficiency associated with lower blood pressure and reduced risk of ischemic heart disease: a cohort study of 91,540 individuals and a meta-analysis

    Winther, S. V., Ahmed, D., Al-Shuweli, S., Landt, E. M., Nordestgaard, B. G., Seersholm, N. & Dahl, M., Dec 2022, In: Respiratory Research. 23, 1, 55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. E-pub ahead of print

    Associations of Alzheimer Disease-Protective APOE Variants With Age-Related Macular Degeneration

    Rasmussen, K. L., Tybjærg-Hansen, A., Nordestgaard, B. G. & Frikke-Schmidt, R., 17 Nov 2022, (E-pub ahead of print) In: JAMA Ophthalmology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. E-pub ahead of print
  9. Published

    Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses

    Gaziano, L., Sun, L., Arnold, M., Bell, S., Cho, K., Kaptoge, S. K., Song, R. J., Burgess, S., Posner, D. C., Mosconi, K., Robinson-Cohen, C., Mason, A. M., Bolton, T. R., Tao, R., Allara, E., Schubert, P., Chen, L., Staley, J. R., Staplin, N., Altay, S. & 31 others, Amiano, P., Arndt, V., Ärnlöv, J., Barr, E. L. M., Björkelund, C., Boer, J. M. A., Brenner, H., Casiglia, E., Chiodini, P., Cooper, J. A., Coresh, J., Cushman, M., Dankner, R., Davidson, K. W., de Jongh, R. T., Donfrancesco, C., Engström, G., Freisling, H., de la Cámara, A. G., Gudnason, V., Hankey, G. J., Hansson, P-O., Heath, A. K., Hoorn, E. J., Imano, H., Jassal, S. K., Kaaks, R., Katzke, V., Nordestgaard, B. G., Wareham, N. & Emerging Risk Factors Collaboration/EPIC-CVD/Million Veteran Program, 15 Nov 2022, In: Circulation. 146, 20, p. 1507-1517 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. E-pub ahead of print

    Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries

    Mishra, A., Malik, R., Hachiya, T., Jürgenson, T., Namba, S., Posner, D. C., Kamanu, F. K., Koido, M., Le Grand, Q., Shi, M., He, Y., Georgakis, M. K., Caro, I., Krebs, K., Liaw, Y-C., Vaura, F. C., Lin, K., Winsvold, B. S., Srinivasasainagendra, V., Parodi, L. & 31 others, Bae, H-J., Chauhan, G., Chong, M. R., Tomppo, L., Akinyemi, R., Roshchupkin, G. V., Habib, N., Jee, Y. H., Thomassen, J. Q., Abedi, V., Cárcel-Márquez, J., Nygaard, M., Leonard, H. L., Yang, C., Yonova-Doing, E., Knol, M. J., Lewis, A. J., Judy, R. L., Ago, T., Amouyel, P., Armstrong, N. D., Bakker, M. K., Bartz, T. M., Bennett, D. A., Bis, J. C., Bordes, C., Børte, S., Nordestgaard, B. G., Tybjærg-Hansen, A., Frikke-Schmidt, R. & COMPASS Consortium, 14 Nov 2022, (E-pub ahead of print)

    Research output: Other contributionResearch

  11. E-pub ahead of print

    Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk

    Das Pradhan, A., Glynn, R. J., Fruchart, J-C., MacFadyen, J. G., Zaharris, E. S., Everett, B. M., Campbell, S. E., Oshima, R., Amarenco, P., Blom, D. J., Brinton, E. A., Eckel, R. H., Elam, M. B., Felicio, J. S., Ginsberg, H. N., Goudev, A., Ishibashi, S., Joseph, J., Kodama, T., Koenig, W. & 17 others, Leiter, L. A., Lorenzatti, A. J., Mankovsky, B., Marx, N., Nordestgaard, B. G., Páll, D., Ray, K. K., Santos, R. D., Soran, H., Susekov, A., Tendera, M., Yokote, K., Paynter, N. P., Buring, J. E., Libby, P., Ridker, P. M. & PROMINENT Investigators, 5 Nov 2022, (E-pub ahead of print) In: The New England journal of medicine.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. E-pub ahead of print

    Kidney function and risk of dementia: Observational study, meta-analysis, and two-sample mendelian randomization study

    Kjaergaard, A. D., Ellervik, C., Witte, D. R., Nordestgaard, B. G., Frikke-Schmidt, R. & Bojesen, S. E., 4 Nov 2022, (E-pub ahead of print) In: European Journal of Epidemiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Plasma adiponectin and risk of asthma: observational analysis, genetic Mendelian randomisation and meta-analysis

    Nielsen, M. B., Nordestgaard, B. G., Benn, M. & Çolak, Y., 1 Nov 2022, In: Thorax. 77, 11, p. 1070-1077 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Clonal haematopoiesis of indeterminate potential and impaired kidney function-A Danish general population study with 11 years follow-up

    Larsen, M. K., Skov, V., Kjaer, L., Møller-Palacino, N. A., Pedersen, R. K., Andersen, M., Ottesen, J. T., Cordua, S., Poulsen, H. E., Dahl, M., Knudsen, T. A., Eickhardt-Dalbøge, C. S., Koschmieder, S., Pedersen, K. M., Çolak, Y., Bojesen, S. E., Nordestgaard, B. G., Stiehl, T., Hasselbalch, H. C. & Ellervik, C., Nov 2022, In: European Journal of Haematology. 109, 5, p. 576-585 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published
  16. Published

    Stroke genetics informs drug discovery and risk prediction across ancestries

    Benn, M., Afzal, S., Kamstrup, P. R., Schnohr, P., Jensen, G. B. & COMPASS Consortium, Nov 2022, In: Nature. 611, 7934, p. 115-123 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    PredictCBC-2.0: a contralateral breast cancer risk prediction model developed and validated in ~ 200,000 patients

    Giardiello, D., Hooning, M. J., Hauptmann, M., Keeman, R., Heemskerk-Gerritsen, B. A. M., Becher, H., Blomqvist, C., Bojesen, S. E., Bolla, M. K., Camp, N. J., Czene, K., Devilee, P., Eccles, D. M., Fasching, P. A., Figueroa, J. D., Flyger, H., García-Closas, M., Haiman, C. A., Hamann, U., Hopper, J. L. & 19 others, Jakubowska, A., Leeuwen, F. E., Lindblom, A., Lubiński, J., Margolin, S., Martinez, M. E., Nevanlinna, H., Nevelsteen, I., Pelders, S., Pharoah, P. D. P., Siesling, S., Southey, M. C., van der Hout, A. H., van Hest, L. P., Chang-Claude, J., Hall, P., Easton, D. F., Steyerberg, E. W. & Schmidt, M. K., 21 Oct 2022, In: Breast Cancer Research. 24, 1, 69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. E-pub ahead of print

    Prognostic value of circulating proteins in patients undergoing surgery for pancreatic cancer

    Lindgaard, S. C., Sztupinszki, Z., Maag, E., Hansen, C. P., Chen, I. M., Johansen, A. Z., Hasselby, J. P., Bojesen, S. E., Nielsen, D. & Johansen, J. S., 17 Oct 2022, (E-pub ahead of print) In: Cancer Medicine.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement

    Kronenberg, F., Mora, S., Stroes, E. S. G., Ference, B. A., Arsenault, B. J., Berglund, L., Dweck, M. R., Koschinsky, M., Lambert, G., Mach, F., McNeal, C. J., Moriarty, P. M., Natarajan, P., Nordestgaard, B. G., Parhofer, K. G., Virani, S. S., von Eckardstein, A., Watts, G. F., Stock, J. K., Ray, K. K. & 2 others, Tokgözoğlu, L. S. & Catapano, A. L., 14 Oct 2022, In: European heart journal. 43, 39, p. 3925-3946 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Traditional and Non-traditional Cardiovascular Risk Factors and Cardiovascular Disease in Women with Psoriasis

    Näslund-Koch, C., Vedel-Krogh, S., Bojesen, S. E. & Skov, L., 11 Oct 2022, In: Acta Dermato-Venereologica. 102, p. adv00789

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published
  22. Published

    Coronary artery- and aortic valve calcifications in patients with Philadelphia-negative myeloproliferative neoplasms

    Solli, C. N., Chamat-Hedemand, S., Elming, H., Ngo, A., Kjær, L., Skov, V., Sørensen, A. L., Ellervik, C., Fuchs, A., Sigvardsen, P. E., Kühl, J. T., Kofoed, K. F., Nordestgaard, B. G., Hasselbalch, H. & Bruun, N. E., 1 Oct 2022, In: International Journal of Cardiology. 364, p. 112-118 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Genome-wide by Environment Interaction Study of Stressful Life Events and Hospital-Treated Depression in the iPSYCH2012 Sample

    Suppli, N. P., Andersen, K. K., Agerbo, E., Rajagopal, V. M., Appadurai, V., Coleman, J. R. I., Breen, G., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Pedersen, C. B., Pedersen, M. G., Thompson, W. K., Munk-Olsen, T., Benros, M. E., Als, T. D., Grove, J., Werge, T., Børglum, A. D., Hougaard, D. M., Mors, O. & 3 others, Nordentoft, M., Mortensen, P. B. & Musliner, K. L., Oct 2022, In: Biological psychiatry global open science. 2, 4, p. 400-410 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study

    Dixon-Suen, S. C., Lewis, S. J., Martin, R. M., English, D. R., Boyle, T., Giles, G. G., Michailidou, K., Bolla, M. K., Wang, Q., Dennis, J., Lush, M., Investigators, A., Ahearn, T. U., Ambrosone, C. B., Andrulis, I. L., Anton-Culver, H., Arndt, V., Aronson, K. J., Augustinsson, A., Auvinen, P. & 31 others, Beane Freeman, L. E., Becher, H., Beckmann, M. W., Behrens, S., Bermisheva, M., Blomqvist, C., Bogdanova, N. V., Bojesen, S. E., Bonanni, B., Brenner, H., Brüning, T., Buys, S. S., Camp, N. J., Campa, D., Canzian, F., Castelao, J. E., Cessna, M. H., Chang-Claude, J., Chanock, S. J., Clarke, C. L., Conroy, D. M., Couch, F. J., Cox, A., Cross, S. S., Czene, K., Daly, M. B., Devilee, P., Dörk, T., Dwek, M., Flyger, H. & Breast Cancer Association Consortium , Oct 2022, In: British Journal of Sports Medicine. 56, 20, p. 1157-1170 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published
  26. Published
  27. E-pub ahead of print
  28. Published

    Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways

    Young, W. J., Lahrouchi, N., Isaacs, A., Duong, T., Foco, L., Ahmed, F., Brody, J. A., Salman, R., Noordam, R., Benjamins, J-W., Haessler, J., Lyytikäinen, L-P., Repetto, L., Concas, M. P., van den Berg, M. E., Weiss, S., Baldassari, A. R., Bartz, T. M., Cook, J. P., Evans, D. S. & 146 others, Freudling, R., Hines, O., Isaksen, J. L., Lin, H., Mei, H., Moscati, A., Müller-Nurasyid, M., Nursyifa, C., Qian, Y., Richmond, A., Roselli, C., Ryan, K. A., Tarazona-Santos, E., Thériault, S., van Duijvenboden, S., Warren, H. R., Yao, J., Raza, D., Aeschbacher, S., Ahlberg, G., Alonso, A., Andreasen, L., Bis, J. C., Boerwinkle, E., Campbell, A., Catamo, E., Cocca, M., Cutler, M. J., Darbar, D., De Grandi, A., De Luca, A., Ding, J., Ellervik, C., Ellinor, P. T., Felix, S. B., Froguel, P., Fuchsberger, C., Gögele, M., Graff, C., Graff, M., Guo, X., Hansen, T., Heckbert, S. R., Huang, P. L., Huikuri, H. V., Hutri-Kähönen, N., Ikram, M. A., Jackson, R. D., Junttila, J., Kavousi, M., Kors, J. A., Leal, T. P., Lemaitre, R. N., Lin, H. J., Lind, L., Linneberg, A., Liu, S., MacFarlane, P. W., Mangino, M., Meitinger, T., Mezzavilla, M., Mishra, P. P., Mitchell, R. N., Mononen, N., Montasser, M. E., Morrison, A. C., Nauck, M., Nauffal, V., Navarro, P., Nikus, K., Pare, G., Patton, K. K., Pelliccione, G., Pittman, A., Porteous, D. J., Pramstaller, P. P., Preuss, M. H., Raitakari, O. T., Reiner, A. P., Ribeiro, A. L. P., Rice, K. M., Risch, L., Schlessinger, D., Schotten, U., Schurmann, C., Shen, X., Shoemaker, M. B., Sinagra, G., Sinner, M. F., Soliman, E. Z., Stoll, M., Strauch, K., Tarasov, K., Taylor, K. D., Tinker, A., Trompet, S., Uitterlinden, A., Völker, U., Völzke, H., Waldenberger, M., Weng, L-C., Whitsel, E. A., Wilson, J. G., Avery, C. L., Conen, D., Correa, A., Cucca, F., Dörr, M., Gharib, S. A., Girotto, G., Grarup, N., Hayward, C., Jamshidi, Y., Järvelin, M-R., Jukema, J. W., Kääb, S., Kähönen, M., Kanters, J. K., Kooperberg, C., Lehtimäki, T., Lima-Costa, M. F., Liu, Y., Loos, R. J. F., Lubitz, S. A., Mook-Kanamori, D. O., Morris, A. P., O'Connell, J. R., Olesen, M. S., Orini, M., Padmanabhan, S., Pattaro, C., Peters, A., Psaty, B. M., Rotter, J. I., Stricker, B., van der Harst, P., van Duijn, C. M., Verweij, N., Wilson, J. F., Arking, D. E., Ramirez, J., Lambiase, P. D., Sotoodehnia, N., Mifsud, B., Newton-Cheh, C. & Munroe, P. B., 1 Sep 2022, In: Nature Communications. 13, 1, p. 5144 5144.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB

    Eliasen, A. U., Pedersen, C. E. T., Rasmussen, M. A., Wang, N., Soverini, M., Fritz, A., Stokholm, J., Chawes, B. L., Morin, A., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Mortensen, P. B., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Mors, O., Nordentoft, M. & 14 others, Børglum, A. D., Werge, T., Agerbo, E., Söderhall, C., Altman, M. C., Thysen, A. H., McKennan, C. G., Brix, S., Gern, J. E., Ober, C., Ahluwalia, T. S., Bisgaard, H., Pedersen, A. G. & Bønnelykke, K., Sep 2022, In: The Journal of allergy and clinical immunology. 150, 3, p. 622-630 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Lipoprotein(a) during COVID-19 hospitalization: Thrombosis, inflammation, and mortality

    Kaltoft, M., Glavind, K. S., Nielsen, S. F., Langsted, A., Iversen, K. K., Nordestgaard, B. G. & Kamstrup, P. R., Sep 2022, In: Atherosclerosis. 357, p. 33-40 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. E-pub ahead of print
  32. Published
  33. Published

    Development and validation of a model to predict incident chronic liver disease in the general population: The CLivD score

    Åberg, F., Luukkonen, P. K., But, A., Salomaa, V., Britton, A., Petersen, K. M., Bojesen, S. E., Balling, M., Nordestgaard, B. G., Puukka, P., Männistö, S., Lundqvist, A., Perola, M., Jula, A. & Färkkilä, M., Aug 2022, In: Journal of Hepatology. 77, 2, p. 302-311 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder

    Rajagopal, V. M., Duan, J., Vilar-Ribó, L., Grove, J., Zayats, T., Ramos-Quiroga, J. A., Satterstrom, F. K., Artigas, M. S., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Als, T. D., Rosengren, A., Daly, M. J., Neale, B. M., Nordentoft, M., Werge, T., Mors, O., Hougaard, D. M., Mortensen, P. B., Ribasés, M. & 2 others, Børglum, A. D. & Demontis, D., Aug 2022, In: Nature Genetics. 54, 8, p. 1117-1124 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published
  36. Published
  37. Published

    Macular Degeneration and CETP Inhibition-Reply

    Nordestgaard, L. T., Nordestgaard, B. G. & Tybjærg-Hansen, A., 1 Jul 2022, In: JAMA Cardiology. 7, 7, p. 775-776 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  38. Published

    Risk of ulcerative colitis and Crohn's disease in smokers lacks causal evidence

    Pedersen, K. M., Çolak, Y., Vedel-Krogh, S., Kobylecki, C. J., Bojesen, S. E. & Nordestgaard, B. G., Jul 2022, In: European Journal of Epidemiology. 37, 7, p. 735-745 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. E-pub ahead of print
  40. Published

    Elevated Remnant Cholesterol Reclassifies Risk of Ischemic Heart Disease and Myocardial Infarction

    Doi, T., Langsted, A. & Nordestgaard, B. G., 21 Jun 2022, In: Journal of the American College of Cardiology. 79, 24, p. 2383-2397 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published
  42. Published
  43. Published
  44. Published

    A rare genetic variant in the manganese transporter SLC30A10 and elevated liver enzymes in the general population

    Seidelin, A-S., Nordestgaard, B. G., Tybjærg-Hansen, A., Yaghootkar, H. & Stender, S., Jun 2022, In: Hepatology International. 16, 3, p. 702-711 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Potential clinical implications of targeted spirometry for detection of COPD: A contemporary population-based cohort study

    Çolak, Y., Nordestgaard, B. G., Vestbo, J., Afzal, S. & Lange, P., Jun 2022, In: Respiratory medicine. 197, 106852.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    High incidence of discrepancies in new Siemens assay - A comparison of cardiac troponin I assays

    Hasselbalch, R. B., Kristensen, J. H., Jørgensen, N., Strandkjær, N., Alaour, B., Afzal, S., Marber, M., Bundgaard, H. & Iversen, K. K., 25 May 2022, In: Clinical Chemistry and Laboratory Medicine. 60, 6, p. 921-929 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Breast cancer risks associated with missense variants in breast cancer susceptibility genes

    Dorling, L., Carvalho, S., Allen, J., Parsons, M. T., Fortuno, C., González-Neira, A., Heijl, S. M., Adank, M. A., Ahearn, T. U., Andrulis, I. L., Auvinen, P., Becher, H., Beckmann, M. W., Behrens, S., Bermisheva, M., Bogdanova, N. V., Bojesen, S. E., Bolla, M. K., Bremer, M., Briceno, I. & 31 others, Camp, N. J., Campbell, A., Castelao, J. E., Chang-Claude, J., Chanock, S. J., Chenevix-Trench, G., Collée, J. M., Czene, K., Dennis, J., Dörk, T., Eriksson, M., Evans, D. G., Fasching, P. A., Figueroa, J., Flyger, H., Gabrielson, M., Gago-Dominguez, M., García-Closas, M., Giles, G. G., Glendon, G., Guénel, P., Gündert, M., Hadjisavvas, A., Hahnen, E., Hall, P., Hamann, U., Harkness, E. F., Hartman, M., Hogervorst, F. B. L., Hollestelle, A. & NBCS Collaborators, 18 May 2022, In: Genome Medicine. 14, 1, p. 51 51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Monocyte count and soluble markers of monocyte activation in people living with HIV and uninfected controls

    Knudsen, A. D., Bouazzi, R., Afzal, S., Gelpi, M., Benfield, T., Høgh, J., Thomsen, M. T., Trøseid, M., Nordestgaard, B. G. & Nielsen, S. D., 11 May 2022, In: BMC Infectious Diseases. 22, 1, p. 1-9 9 p., 451.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published
  50. Published
  51. Published
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