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Institute for Biological Psychiatry - a part of Copenhagen University Hospital
  1. 2016
  2. Published

    Genome-Wide Association Studies Suggest Limited Immune Gene Enrichment in Schizophrenia Compared to 5 Autoimmune Diseases

    Pouget, J. G., Gonçalves, V. F., Spain, S. L., Finucane, H. K., Raychaudhuri, S., Kennedy, J. L., Knight, J. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, Sep 2016, In : Schizophrenia Bulletin. 42, 5, p. 1176-84 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

    Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K-H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M., Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H., Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A-P., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Ridker, P. M., Hrafnsdottir, M. G., Stefansson, H., Ring, S. M., Hottenga, J-J., Penninx, B. W. J. H., Färkkilä, M., Artto, V., Kaunisto, M., Vepsäläinen, S., Malik, R., Heath, A. C., Madden, P. A. F., Martin, N. G., Esserlind, A-L., Christensen, A. F., Hansen, T. F., Werge, T., Olesen, J. & International Headache Genetics Consortium, Aug 2016, In : Nature Genetics. 48, 8, p. 856-66 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Persistent gating deficit and increased sensitivity to NMDA receptor antagonism after puberty in a new mouse model of the human 22q11.2 microdeletion syndrome: a study in male mice

    Didriksen, M., Fejgin, K., Nilsson, S. R. O., Birknow, M. R., Grayton, H. M., Larsen, P. H., Lauridsen, J. B., Nielsen, V., Celada, P., Santana, N., Kallunki, P., Christensen, K. V., Werge, T. M., Stensbøl, T. B., Egebjerg, J., Gastambide, F., Artigas, F., Bastlund, J. F. & Nielsen, J., 7 Jul 2016, In : Journal of psychiatry & neuroscience : JPN. 41, 5, p. 150381

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    High loading of polygenic risk in cases with chronic schizophrenia

    Meier, S. M., Agerbo, E., Maier, R., Pedersen, C. B., Lang, M., Grove, J., Hollegaard, M. V., Demontis, D., Trabjerg, B. B., Hjorthøj, C., Ripke, S., Degenhardt, F., Nöthen, M. M., Rujescu, D., Maier, W., Werge, T., Mors, O., Hougaard, D. M., Børglum, A., Wray, N. R., Rietschel, M., Nordentoft, M., Mortensen, P. B., Mattheisen, M. & MooDS SCZ Consortium, Jul 2016, In : Molecular Psychiatry. 21, 7, p. 969-74 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The association between candidate migraine susceptibility loci and severe migraine phenotype in a clinical sample

    Esserlind, A-L., Christensen, A. F., Steinberg, S., Grarup, N., Pedersen, O., Hansen, T., Werge, T., Hansen, T. F., Husemoen, L. L. N., Linneberg, A., Budtz-Jorgensen, E., Westergaard, M. L., Stefansson, H. & Olesen, J., 9 Jun 2016, In : Cephalalgia : an international journal of headache. 36, 7, p. 615-23

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Investigating the impact of missense mutations in hCES1 by in silico structure-based approaches

    Nzabonimpa, G. S., Rasmussen, H. B., Brunak, S., Taboureau, O., INDICES Consortium, Plessen, K. J., Jeppesen, P., Houmann, T., Kaalund-Brok, K. & Pagsberg, A. K., 1 Jun 2016, In : Drug Metabolism and Personalized Therapy. 31, 2, p. 97-106

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

    Winkler, T. W., Justice, A. E., Graff, M., Barata, L., Feitosa, M. F., Chu, S., Czajkowski, J., Esko, T., Fall, T., Kilpeläinen, T. O., Lu, Y., Mägi, R., Mihailov, E., Pers, T. H., Rüeger, S., Teumer, A., Ehret, G. B., Ferreira, T., Heard-Costa, N. L., Karjalainen, J., Lagou, V., Mahajan, A., Neinast, M. D., Prokopenko, I., Simino, J., Teslovich, T. M., Jansen, R., Westra, H-J., White, C. C., Absher, D., Ahluwalia, T. S., Ahmad, S., Albrecht, E., Alves, A. C., Bragg-Gresham, J. L., de Craen, A. J. M., Bis, J. C., Bonnefond, A., Boucher, G., Cadby, G., Cheng, Y-C., Chiang, C. W. K., Friedrich, N., Husemoen, L. L., Jørgensen, T., Linneberg, A., Ribel-Madsen, R., Sparsø, T. H., Schwarz, P. E. H., Sørensen, T. I. A. & arcOGEN Consortium, Jun 2016

    Research output: Other contributionResearch

  9. Published

    Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study

    Prins, B. P., Abbasi, A., Wong, A., Vaez, A., Nolte, I., Franceschini, N., Stuart, P. E., Guterriez Achury, J., Mistry, V., Bradfield, J. P., Valdes, A. M., Bras, J., Shatunov, A., Lu, C., Han, B., Raychaudhuri, S., Bevan, S., Mayes, M. D., Tsoi, L. C., Evangelou, E., Nair, R. P., Grant, S. F. A., Polychronakos, C., Radstake, T. R. D., van Heel, D. A., Dunstan, M. L., Wood, N. W., Al-Chalabi, A., Dehghan, A., Hakonarson, H., Markus, H. S., Elder, J. T., Knight, J., Arking, D. E., Spector, T. D., Koeleman, B. P. C., van Duijn, C. M., Martin, J., Morris, A. P., Weersma, R. K., Wijmenga, C., Munroe, P. B., Perry, J. R. B., Pouget, J. G., Jamshidi, Y., Snieder, H., Alizadeh, B. Z. & PAGE Consortium, Jun 2016, In : PLOS Medicine. 13, 6, p. e1001976

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women

    Mehta, D., Tropf, F. C., Gratten, J., Bakshi, A., Zhu, Z., Bacanu, S-A., Hemani, G., Magnusson, P. K. E., Barban, N., Esko, T., Metspalu, A., Snieder, H., Mowry, B. J., Kendler, K. S., Yang, J., Visscher, P. M., McGrath, J. J., Mills, M. C., Wray, N. R., Lee, S. H., Andreassen, O. A., Bramon, E., Bruggeman, R., Buxbaum, J. D., Cairns, M. J., Cantor, R. M., Cloninger, C. R., Cohen, D., Crespo-Facorro, B., Darvasi, A., DeLisi, L. E., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Escott-Price, V., Freimer, N. B., Georgieva, L., de Haan, L., Henskens, F. A., Joa, I., Julià, A., Khrunin, A., Lerer, B., Limborska, S., Loughland, C. M., Macek, M. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, LifeLines Cohort Study, and TwinsUK, 1 May 2016, In : JAMA Psychiatry. 73, 5, p. 497-505 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population

    Robinson, E. B., St Pourcain, B., Anttila, V., Kosmicki, J. A., Bulik-Sullivan, B., Grove, J., Maller, J., Samocha, K. E., Sanders, S. J., Ripke, S., Martin, J., Hollegaard, M. V., Werge, T., Hougaard, D. M., Hansen, T. F., Neale, B. M., Evans, D. M., Skuse, D., Mortensen, P. B., Børglum, A. D., Ronald, A., Smith, G. D., Daly, M. J., iPSYCH-SSI-Broad Autism Group & Nordentoft, M., May 2016, In : Nature Genetics. 48, 5, p. 552-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders

    Isles, A. R., Ingason, A., Lowther, C., Walters, J., Gawlick, M., Stöber, G., Rees, E., Martin, J., Little, R. B., Potter, H., Georgieva, L., Pizzo, L., Ozaki, N., Aleksic, B., Kushima, I., Ikeda, M., Iwata, N., Levinson, D. F., Gejman, P. V., Shi, J., Sanders, A. R., Duan, J., Willis, J., Sisodiya, S., Costain, G., Werge, T. M., Degenhardt, F., Giegling, I., Rujescu, D., Hreidarsson, S. J., Saemundsen, E., Ahn, J. W., Ogilvie, C., Girirajan, S. D., Stefansson, H., Stefansson, K., O'Donovan, M. C., Owen, M. J., Bassett, A. & Kirov, G., May 2016, In : P L o S Genetics. 12, 5, p. e1005993

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Schizophrenia Spectrum Disorders in a Danish 22q11.2 Deletion Syndrome Cohort Compared to the Total Danish Population-A Nationwide Register Study

    Vangkilde, A., Olsen, L., Hoeffding, L. K., Pedersen, C. B., Mortensen, P. B., Werge, T. & Trabjerg, B., May 2016, In : Schizophrenia Bulletin. 42, 3, p. 824-831

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published
  15. Published

    Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

    Franke, B., Stein, J. L., Ripke, S., Anttila, V., Hibar, D. P., van Hulzen, K. J. E., Arias-Vasquez, A., Smoller, J. W., Nichols, T. E., Neale, M. C., McIntosh, A. M., Lee, P., McMahon, F. J., Meyer-Lindenberg, A., Mattheisen, M., Andreassen, O. A., Gruber, O., Sachdev, P. S., Roiz-Santiañez, R., Saykin, A. J., Ehrlich, S., Mather, K. A., Turner, J. A., Schwarz, E., Thalamuthu, A., Yao, Y., Ho, Y. Y. W., Martin, N. G., Wright, M. J., O'Donovan, M. C., Thompson, P. M., Neale, B. M., Medland, S. E., Sullivan, P. F. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, Mar 2016, In : Nature Neuroscience. 19, 3, p. 420-31 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics

    Holland, D., Wang, Y., Thompson, W. K., Schork, A., Chen, C-H., Lo, M-T., Witoelar, A., Werge, T., O'Donovan, M., Andreassen, O. A., Dale, A. M. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 16 Feb 2016, In : Frontiers in genetics. 7, p. 15

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Schizophrenia risk from complex variation of complement component 4

    Sekar, A., Bialas, A. R., de Rivera, H., Davis, A., Hammond, T. R., Kamitaki, N., Tooley, K., Presumey, J., Baum, M., Van Doren, V., Genovese, G., Rose, S. A., Handsaker, R. E., Daly, M. J., Carroll, M. C., Stevens, B., McCarroll, S. A. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, Feb 2016, In : Nature. 530, 7589, p. 177-183

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published
  19. Published

    Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes

    Pers, T. H., Timshel, P., Ripke, S., Lent, S., Sullivan, P. F., O'Donovan, M. C., Franke, L., Hirschhorn, J. N., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Hansen, T. F., Werge, T. M. & Olsen, L., 10 Jan 2016, In : Human Molecular Genetics. 25, 6, p. 1247-1254

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS

    Wang, Y., Thompson, W. K., Schork, A. J., Holland, D., Chen, C-H., Bettella, F., Desikan, R. S., Li, H. W., Witoelar, A., Zuber, V., Devor, A., Nöthen, M. M., Rietschel, M., Chen, Q., Werge, T., Cichon, S., Weinberger, D. R., Djurovic, S., O'Donovan, M., Visscher, P. M., Andreassen, O. A., Dale, A. M. & Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium, Jan 2016, In : P L o S Genetics (Online). 12, 1, p. e1005803 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    15q13.3 homozygous knockout mouse model display epilepsy-, autism- and schizophrenia-related phenotypes

    Forsingdal, A., Fejgin, K., Nielsen, V., Werge, T. & Nielsen, J., 2016, In : Translational psychiatry. 6, 7, p. e860

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published
  23. Published

    High-Quality Exome Sequencing of Whole-Genome Amplified Neonatal Dried Blood Spot DNA

    Poulsen, J. B., Lescai, F., Grove, J., Bækvad-Hansen, M., Christiansen, M., Hagen, C. M., Maller, J., Stevens, C., Li, S., Li, Q., Sun, J., Wang, J., Nordentoft, M., Werge, T. M., Mortensen, P. B., Børglum, A. D., Daly, M., Hougaard, D. M., Bybjerg-Grauholm, J. & Hollegaard, M. V., 2016, In : P L o S One. 11, 4, p. e0153253

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Investigation of SNP rs2060546 Immediately Upstream to NTN4 in a Danish Gilles de la Tourette Syndrome Cohort

    Padmanabhuni, S. S., Houssari, R., Esserlind, A-L., Olesen, J., Werge, T. M., Hansen, T. F., Bertelsen, B., Tsetsos, F., Paschou, P. & Tümer, Z., 2016, In : Frontiers in Neuroscience. 10, p. 531

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Risk of Mental Disorders in 22q11.2 Deletion and Duplication Syndrome: A Nation-wide Study.

    Høffding, L. K. E., Olsen, L., Mazin, W., Vangkilde, A. & Werge, T. M., 2016.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  26. Published

    RNA Sequencing of Trigeminal Ganglia in Rattus Norvegicus after Glyceryl Trinitrate Infusion with Relevance to Migraine

    Hougaard Pedersen, S., Maretty, L., Ramachandran, R., Sibbesen, J. A., Yakimov, V., Elgaard-Christensen, R., Hansen, T. F., Krogh, A., Olesen, J. & Jansen-Olesen, I., 2016, In : P L o S One. 11, 5, p. e0155039

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Switch in Therapy from Methylphenidate to Atomoxetine in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: An Analysis of Patient Records

    Warrer, P., Thomsen, P. H., Dalsgaard, S., Hansen, E. H., Aagaard, L., Wallach Kildemoes, H. & Rasmussen, H. B., 2016, In : Journal of Child and Adolescent Psychopharmacology. 26, 4, p. 354-361

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The effect of COMT val158met genotype on neural response and performance during spatial working memory in remitted patients with bipolar disorder

    Høffding, L. K. E., 2016.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  29. Published

    Transcriptional interactions suggest niche segregation among microorganisms in the human gut

    Plichta, D. R., Juncker, A. S., Bertalan, M., Rettedal, E., Gautier, L., Varela, E., Manichanh, C., Fouqueray, C., Levenez, F., Nielsen, T., Doré, J., Machado, A. M. D., de Evgrafov, M. C. R., Hansen, T., Jørgensen, T., Bork, P., Guarner, F., Pedersen, O., Sommer, M. O. A., Ehrlich, S. D., Sicheritz-Pontén, T., Brunak, S., Nielsen, H. B. & Metagenomics of the Human Intestinal Tract (MetaHIT) Consortium, 2016, In : Future Microbiology. 1, p. 16152

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2015
  31. Published

    Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

    Bigdeli, T. B., Ripke, S., Bacanu, S-A., Lee, S. H., Wray, N. R., Gejman, P. V., Rietschel, M., Cichon, S., St Clair, D., Corvin, A., Kirov, G., McQuillin, A., Gurling, H., Rujescu, D., Andreassen, O. A., Werge, T., Blackwood, D. H. R., Pato, C. N., Pato, M. T., Malhotra, A. K., O'Donovan, M. C., Kendler, K. S., Fanous, A. H. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 11 Dec 2015, In : American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies

    Thompson, W. K., Wang, Y., Schork, A. J., Witoelar, A., Zuber, V., Xu, S., Werge, T., Holland, D., Andreassen, O. A., Dale, A. M. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, Dec 2015, In : P L o S Genetics (Online). 11, 12, p. e1005717

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published
  34. Published

    Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

    Loh, P-R., Bhatia, G., Gusev, A., Finucane, H. K., Bulik-Sullivan, B. K., Pollack, S. J., de Candia, T. R., Lee, S. H., Wray, N. R., Kendler, K. S., O'Donovan, M. C., Neale, B. M., Patterson, N., Price, A. L. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, Dec 2015, In : Nature Genetics. 47, 12, p. 1385-92 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Linkage and whole genome sequencing identify a locus on 6q25-26 for formal thought disorder and implicate MEF2A regulation

    Thygesen, J. H., Zambach, S. K., Ingason, A., Lundin, P., Hansen, T. F., Berlatan, M., Rosengren, A., Bjerre, D., Ferrero-Miliani, L., Rasmussen, H. B., Parnas, J. & Werge, T., Dec 2015, In : Schizophrenia Research. 169, 1-3, p. 441–446

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Identification of rare high-risk copy number variants affecting the dopamine transporter gene in mental disorders

    Hoeffding, L. K., Duong, L. T. T., Ingason, A., Rosengren, A., Sorbanski, E., Witt, S. H., Djurovic, S., Andreassen, O. A., Hansen, T. F., Werge, T. & Rasmussen, H. B., 11 Nov 2015, In : Nordic Journal of Psychiatry. p. 1-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Two rare deletions upstream of the NRXN1 gene (2p16.3) affecting the non-coding mRNA AK127244 segregate with diverse psychopathological phenotypes in a family

    Duong, L. T., Hoeffding, L. K., Petersen, K., Knudsen, H. C., Thygesen, J. H., Klitten, L. L., Tommerup, N., Ingason, A. & Werge, T., 9 Nov 2015, In : European Journal of Medical Genetics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    An atlas of genetic correlations across human diseases and traits

    Bulik-Sullivan, B., Finucane, H. K., Anttila, V., Gusev, A., Day, F. R., Loh, P-R., Duncan, L., Perry, J. R. B., Patterson, N., Robinson, E. B., Daly, M. J., Price, A. L., Neale, B. M. & ReproGen Consortium, Nov 2015, In : Nature Genetics. 47, 11, p. 1236-41 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Correction: Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate

    Andreassen, O. A., Thompson, W. K., Schork, A. J., Ripke, S., Mattingsdal, M., Kelsoe, J. R., Kendler, K. S., O'Donovan, M. C., Rujescu, D., Werge, T., Sklar, P., Roddey, J. C., Chen, C-H., McEvoy, L., Desikan, R. S., Djurovic, S., Dale, A. M. & Psychiatric Genomics Consortium (PGC), Nov 2015, In : P L o S Genetics (Online). 11, 11, p. e1005544

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Partitioning heritability by functional annotation using genome-wide association summary statistics

    Finucane, H. K., Bulik-Sullivan, B., Gusev, A., Trynka, G., Reshef, Y., Loh, P-R., Anttila, V., Xu, H., Zang, C., Farh, K., Ripke, S., Day, F. R., Purcell, S., Stahl, E., Lindstrom, S., Perry, J. R. B., Okada, Y., Raychaudhuri, S., Daly, M. J., Patterson, N., Neale, B. M., Price, A. L. & ReproGen Consortium, Nov 2015, In : Nature Genetics. 47, 11, p. 1228-35 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Population genetic differentiation of height and body mass index across Europe

    Robinson, M. R., Hemani, G., Medina-Gomez, C., Mezzavilla, M., Esko, T., Shakhbazov, K., Powell, J. E., Vinkhuyzen, A., Berndt, S. I., Gustafsson, S., Justice, A. E., Kahali, B., Locke, A. E., Pers, T. H., Vedantam, S., Wood, A. R., van Rheenen, W., Andreassen, O. A., Gasparini, P., Metspalu, A., Berg, L. H. V. D., Veldink, J. H., Rivadeneira, F., Werge, T. M., Abecasis, G. R., Boomsma, D. I., Chasman, D. I., de Geus, E. J. C., Frayling, T. M., Hirschhorn, J. N., Hottenga, J. J., Ingelsson, E., Loos, R. J. F., Magnusson, P. K. E., Martin, N. G., Montgomery, G. W., North, K. E., Pedersen, N. L., Spector, T. D., Speliotes, E. K., Goddard, M. E., Yang, J. & Visscher, P. M., Nov 2015, In : Nature Genetics. 47, 11, p. 1357-62 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Genetic Markers of Human Evolution Are Enriched in Schizophrenia

    Srinivasan, S., Bettella, F., Mattingsdal, M., Wang, Y., Witoelar, A., Schork, A. J., Thompson, W. K., Zuber, V., Winsvold, B. S., Zwart, J-A., Collier, D. A., Desikan, R. S., Melle, I., Werge, T., Dale, A. M., Djurovic, S., Andreassen, O. A. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, The International Headache Genetics Consortium, 21 Oct 2015, In : Biological Psychiatry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Vilhjálmsson, B. J., Yang, J., Finucane, H. K., Gusev, A., Lindström, S., Ripke, S., Genovese, G., Loh, P-R., Bhatia, G., Do, R., Hayeck, T., Won, H-H., Kathiresan, S., Pato, M., Pato, C., Tamimi, R., Stahl, E., Zaitlen, N., Pasaniuc, B., Belbin, G., Kenny, E. E., Schierup, M. H., De Jager, P., Patsopoulos, N. A., McCarroll, S., Daly, M., Purcell, S., Chasman, D., Neale, B., Goddard, M., Visscher, P. M., Kraft, P., Patterson, N., Price, A. L. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 1 Oct 2015, In : American Journal of Human Genetics. 97, 4, p. 576-92 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case–control sample of schizophrenia

    Ingason, A., Giegling, I., Harmann, AM., Genius, J., Konte, B., Fried, M., of the Psychaitric Genomics Consortium, S. W. G., Ripke, S., Sullivan, P. F., St Clair, D., Collier, D., O'Donovan, M. C., Mirnics, K., Rujescu, D., Hansen, T. F., Werge, T. M. & Olsen, L., Oct 2015, In : Translational Psychiatry. 5, 10, p. e656 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

    Lee, S. H., Byrne, E. M., Hultman, C. M., Kähler, A., Vinkhuyzen, A. A., Ripke, S., Andreassen, O. A., Frisell, T., Gusev, A., Hu, X., Karlsson, R., Mantzioris, V. X., McGrath, J. J., Mehta, D., Stahl, E. A., Zhao, Q., Kendler, K. S., Sullivan, P. F., Price, A. L., O'Donovan, M., Okada, Y., Mowry, B. J., Raychaudhuri, S., Wray, N. R., Byerley, W., Cahn, W., Cantor, R. M., Cichon, S., Cormican, P., Curtis, D., Djurovic, S., Escott-Price, V., Gejman, P. V., Georgieva, L., Giegling, I., Hansen, T. F., Ingason, A., Kim, Y., Konte, B., Lee, P. H., McIntosh, A., McQuillin, A., Morris, D. W., Nöthen, M. M., O'Dushlaine, C., Olincy, A., Olsen, L., Pato, C. N., Rasmussen, H. B., Werge, T. & Schizophrenia Working Group of the Psychiatric Genomics Consortium and Rheumatoid Arthritis Consortium International, Oct 2015, In : International Journal of Epidemiology. 44, 5, p. 1706-1721

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Risk factors and mortality among patients with severe muco-cutaneous drug reactions

    Crüger, A-M. T., Kaur-Knudsen, D., Zachariae, C., Rasmussen, H. B. & Thomsen, S. F., Aug 2015, In : Danish Medical Bulletin (Online). 62, 8, A5122.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Genetic characterization of blood spot-derived DNA from 209 individuals known to carry 22q11Del reveals a new nested deletion

    Sparsø, T. H., Jun 2015, In : European journal of human genetics : EJHG. PS09.003

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  48. Published

    Evaluating historical candidate genes for schizophrenia

    Farrell, M. S., Werge, T., Sklar, P., Owen, M. J., Ophoff, R. A., O'Donovan, M. C., Corvin, A., Cichon, S. & Sullivan, P. F., May 2015, In : Molecular Psychiatry. 20, 5, p. 555-62 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics

    Rasmussen, H. B., Bjerre, D., Linnet, K., Jürgens, G., Dalhoff, K., Stefansson, H., Hankemeier, T., Kaddurah-Daouk, R., Taboureau, O., Brunak, S., Houmann, T., Jeppesen, P., Pagsberg, A. K., Plessen, K., Dyrborg, J., Hansen, P. R., Hansen, P. E., Hughes, T., Werge, T., INDICES Consortium & Kaalund-Brok, K., 21 Apr 2015, In : Pharmacogenomics. 16, 6, p. 649-665 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  50. Published

    Antipsychotic-Like Effect of the Muscarinic Acetylcholine Receptor Agonist BuTAC in Non-Human Primates

    Andersen, M. B., Croy, C. H., Dencker, D., Werge, T., Bymaster, F. P., Felder, C. C. & Fink-Jensen, A., 17 Apr 2015, In : P L o S One. 10, 4, p. e0122722

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published
  52. Published

    Genetics of Complex Traits and Disorders Discovery and impact of rare variants

    Thygesen, J. H., Mar 2015

    Research output: Book/ReportPh.D. thesisResearch

ID: 49228305