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Copenhagen Trial Unit - a part of Copenhagen University Hospital
  1. 2018
  2. Published

    Antibiotic prophylaxis versus placebo or no intervention for people with cirrhosis and variceal bleeding (Protocol)

    Sanchez-Jimenez, B., Chavez-Tapia, NC., Jakobsen, J. C., Nikolova, D. K. & Gluud, C., 2018, In : Cochrane Database of Systematic Reviews. 11, p. CD013175

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Cochrane corner: complete versus culprit-only revascularisation in ST segment elevation myocardial infarction with multivessel disease

    Bravo, C. A., Hirji, S. A., Bhatt, D. L., Gluud, C., Faxon, D. P., Ohman, E. M., Kaneko, T., Engstrøm, T., Høfsten, D. E. & Brennan, J. M., 2018, In : Heart (British Cardiac Society). 104, 14, p. 1144-1147

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Cochrane Corner: drug-eluting stents versus bare-metal stents for acute coronary syndrome

    Feinberg, J., Nielsen, E. E., Gluud, C. & Jakobsen, J. C., 2018, In : Heart (British Cardiac Society). 104, 23, p. 1895-1897

    Research output: Contribution to journalEditorialResearchpeer-review

  5. Published
  6. Published
  7. Published

    Hallucinations and other psychotic symptoms in response to methylphenidate in children and adolescents with attention-deficit/hyperactivity disorder: a Cochrane systematic review with meta-analysis and trial sequential analysis

    Ramstad, E., Storebø, O. J., Gerner, T., Krogh, H. B., Holmskov, M., Magnusson, F. L., Moreira-Maia, C. R., Skoog, M., Groth, C., Gillies, D., Zwi, M., Kirubakaran, R., Gluud, C. & Simonsen, E., 2018, In : Scandinavian Journal of Child and Adolescent Psychiatry and Psychology. 6, 1, p. 52-71

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published
  9. Published

    Intensive care doctors' preferences for arterial oxygen tension levels in mechanically ventilated patients

    Schjørring, O. L., Toft-Petersen, A. P., Kusk, K. H., Mouncey, P., Sørensen, E. E., Berezowicz, P., Bestle, M. H., Bülow, H-H., Bundgaard, H., Christensen, S., Iversen, S. A., Kirkeby-Garstad, I., Krarup, K. B., Kruse, M., Laake, J. H., Liboriussen, L., Laebel, R. L., Okkonen, M., Poulsen, L. M., Russell, L., Sjövall, F., Sunde, K., Søreide, E., Waldau, T., Walli, A. R., Perner, A., Wetterslev, J. & Rasmussen, B. S., 2018, In : Acta Anaesthesiologica Scandinavica. 62, p. 1443-1451

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published
  11. Published

    Metformin monotherapy for adults with type 2 diabetes mellitus (Protocol)

    Gnesin, F., Thuesen, A. C. B., Kähler, L. K., Gluud, C., Madsbad, S. & Hemmingsen, B., 2018, In : Cochrane Database of Systematic Reviews. 1, p. CD012906

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Oxygen supplementation for critically ill patients-A protocol for a systematic review

    Barbateskovic, M., Schjørring, O. L., Jakobsen, J. C., Meyhoff, C. S., Rasmussen, B. S., Perner, A. & Wetterslev, J., 2018, In : Acta Anaesthesiologica Scandinavica. 62, 7, p. 1020-1030

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Pantoprazole in Patients at Risk for Gastrointestinal Bleeding in the ICU

    Krag, M., Marker, S., Perner, A., Wetterslev, J., Wise, M. P., Schefold, J. C., Keus, F., Guttormsen, A. B., Bendel, S., Borthwick, M., Lange, T., Rasmussen, B. S., Siegemund, M., Bundgaard, H., Elkmann, T., Jensen, J. V., Nielsen, R. D., Liboriussen, L., Bestle, M. H., Elkjær, J. M., Palmqvist, D. F., Bäcklund, M., Laake, J. H., Bådstøløkken, P. M., Grönlund, J., Breum, O., Walli, A., Winding, R., Iversen, S., Jarnvig, I-L., White, J. O., Brand, B., Madsen, M. B., Quist, L., Thornberg, K. J., Møller, A., Wiis, J., Granholm, A., Anthon, C. T., Meyhoff, T. S., Hjortrup, P. B., Aagaard, S. R., Andreasen, J. B., Sørensen, C. A., Haure, P., Andersen, K. L. D., Sølling, C., Engstrøm, J., Agerholm-Larsen, B. & Møller, M. H., 2018, In : The New England journal of medicine. 379, 23, p. 2199-2208

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published
  15. Published

    Prevalence and risk factors related to haloperidol use for delirium in adult intensive care patients: the multinational AID-ICU inception cohort study

    Collet, M. O., Caballero, J., Sonneville, R., Bozza, F. A., Nydahl, P., Schandl, A., Wøien, H., Citerio, G., van den Boogaard, M., Hästbacka, J., Haenggi, M., Colpaert, K., Rose, L., Barbateskovic, M., Lange, T., Jensen, A., Krog, M. B., Egerod, I., Nibro, H. L., Wetterslev, J., Perner, A. & AID-ICU cohort study co-authors, 2018, In : Intensive Care Medicine. 44, 7, p. 1081-1089

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Prognostic value of routinely available data in patients with stable coronary heart disease. A 10-year follow-up of patients sampled at random times during their disease course

    Winkel, P., Jakobsen, J. C., Hilden, J., Jensen, G., Kjøller, E., Sajadieh, A., Kastrup, J., Kolmos, H. J., Larsson, A., Ärnlöv, J. & Gluud, C., 2018, In : Open Heart. 5, 2, p. e000808

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Response to: Revisiting the impact of red cell storage duration on adverse outcomes after transfusion

    Rygård, S. L., Perner, A. & Wetterslev, J., 2018, In : Acta Anaesthesiologica Scandinavica. 62, p. 1163–1164

    Research output: Contribution to journalLetterResearchpeer-review

  18. Published
  19. Published
  20. Published

    Systematic overview and critical appraisal of meta-analyses of interventions in intensive care medicine

    Koster, T. M., Wetterslev, J., Gluud, C., Keus, F. & van der Horst, I. C. C., 2018, In : Acta Anaesthesiologica Scandinavica. 62, p. 1041–1049

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published
  22. Published

    Timing of onset of gastrointestinal bleeding in the ICU: Protocol for a preplanned observational study

    Granholm, A., Lange, T., Anthon, C. T., Marker, S., Krag, M., Meyhoff, T. S., Wise, M. P., Borthwick, M., Bendel, S., Keus, F., Guttormsen, A. B., Schefold, J. C., Wetterslev, J., Perner, A. & Møller, M. H., 2018, In : Acta Anaesthesiologica Scandinavica. 62, p. 1165–1170

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    β-Thalassemia heterozygote state detrimentally affects health expectation

    Graffeo, L., Vitrano, A., Scondotto, S., Dardanoni, G., Pollina Addario, W. S., Giambona, A., Sacco, M., Di Maggio, R., Renda, D., Taormina, F., Triveri, A., Attanasio, M., Gluud, C. & Maggio, A., 2018, In : European Journal of Internal Medicine. 54, p. 76-80

    Research output: Contribution to journalReviewResearchpeer-review

  24. 2017
  25. Published

    STRIDER (Sildenafil TheRapy in dismal prognosis early onset fetal growth restriction): an international consortium of randomised placebo-controlled trials

    Pels, A., Kenny, L. C., Alfirevic, Z., Baker, P. N., von Dadelszen, P., Gluud, C., Kariya, C. T., Mol, B. W., Papageorghiou, A. T., van Wassenaer-Leemhuis, A. G., Ganzevoort, W., Groom, K. M. & international STRIDER Consortium, 28 Dec 2017, In : BMC Pregnancy and Childbirth. 17, 1, p. 440

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Sharing and reuse of individual participant data from clinical trials: principles and recommendations

    Ohmann, C., Banzi, R., Canham, S., Battaglia, S., Matei, M., Ariyo, C., Becnel, L., Bierer, B., Bowers, S., Clivio, L., Dias, M., Druml, C., Faure, H., Fenner, M., Galvez, J., Ghersi, D., Gluud, C., Groves, T., Houston, P., Karam, G., Kalra, D., Knowles, R. L., Krleža-Jerić, K., Kubiak, C., Kuchinke, W., Kush, R., Lukkarinen, A., Marques, P. S., Newbigging, A., O'Callaghan, J., Ravaud, P., Schlünder, I., Shanahan, D., Sitter, H., Spalding, D., Tudur-Smith, C., van Reusel, P., van Veen, E-B., Visser, G. R., Wilson, J. & Demotes-Mainard, J., 14 Dec 2017, In : BMJ Open. 7, 12, p. e018647

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Thrombolysis for acute upper extremity deep vein thrombosis

    Feinberg, J., Nielsen, E. E. & Jakobsen, J. C., 11 Dec 2017, In : Cochrane Database of Systematic Reviews. 12, p. CD012175

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published
  29. Published

    Statistical analysis plan for the EuroHYP-1 trial: European multicentre, randomised, phase III clinical trial of the therapeutic hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke

    Winkel, P., Bath, P. M., Gluud, C., Lindschou, J., van der Worp, H. B., Macleod, M. R., Szabo, I., Durand-Zaleski, I., Schwab, S. & EuroHYP-1 trial investigators, 29 Nov 2017, In : Trials. 18, 1, p. 573

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    A systematic literature review of evidence-based clinical practice for rare diseases: what are the perceived and real barriers for improving the evidence and how can they be overcome?

    Rath, A., Salamon, V., Peixoto, S., Hivert, V., Laville, M., Segrestin, B., Neugebauer, E. A. M., Eikermann, M., Bertele, V., Garattini, S., Wetterslev, J., Banzi, R., Jakobsen, J. C., Djurisic, S., Kubiak, C., Demotes-Mainard, J. & Gluud, C., 22 Nov 2017, In : Trials. 18, 1, p. 556

    Research output: Contribution to journalReviewResearchpeer-review

  31. Published

    Vitamin D supplementation for chronic liver diseases in adults

    Bjelakovic, G., Nikolova, D., Bjelakovic, M. & Gluud, C., 3 Nov 2017, In : Cochrane Database of Systematic Reviews. 11, p. CD011564

    Research output: Contribution to journalReviewResearchpeer-review

  32. Published

    Glucocorticosteroids for people with alcoholic hepatitis

    Pavlov, C. S., Varganova, D. L., Casazza, G., Tsochatzis, E., Nikolova, D. & Gluud, C., 2 Nov 2017, In : Cochrane Database of Systematic Reviews. 11, p. CD001511

    Research output: Contribution to journalReviewResearchpeer-review

  33. Published

    Severe crush injury to the lower extremity after a snowmobile accident in rural Greenland

    Lorentzen, A. K. & Penninga, L., 20 Oct 2017, In : BMJ Case Reports . 2017

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    PANSAID-PAracetamol and NSAID in combination: detailed statistical analysis plan for a randomised, blinded, parallel, four-group multicentre clinical trial

    Thybo, K. H., Jakobsen, J. C., Hägi-Pedersen, D., Pedersen, N. A., Dahl, J. B., Schrøder, H. M., Bulow, H-H., Bjørck, J. G., Overgaard, S., Mathiesen, O. & Wetterslev, J., 10 Oct 2017, In : Trials. 18, 1, p. 465

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Benefit and harm of pregabalin in acute pain treatment: a systematic review with meta-analyses and trial sequential analyses

    Fabritius, M. L., Strøm, C., Koyuncu, S., Jæger, P., Petersen, P. L., Geisler, A., Wetterslev, J., Dahl, J. B. & Mathiesen, O., 1 Oct 2017, In : British Journal of Anaesthesia. 119, 4, p. 775-791 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Clinical examination, critical care ultrasonography and outcomes in the critically ill: cohort profile of the Simple Intensive Care Studies-I

    Hiemstra, B., Eck, R. J., Koster, G., Wetterslev, J., Perner, A., Pettilä, V., Snieder, H., Hummel, Y. M., Wiersema, R., de Smet, A. M. G. A., Keus, F., van der Horst, I. C. C. & SICS Study Group, 27 Sep 2017, In : B M J Open. 7, 9, p. e017170

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Direct-acting antivirals for chronic hepatitis C

    Jakobsen, J. C., Nielsen, E. E., Feinberg, J., Katakam, K. K., Fobian, K., Hauser, G., Poropat, G., Djurisic, S., Weiss, K. H., Bjelakovic, M., Bjelakovic, G., Klingenberg, S. L., Gluud, C., Nikolova, D., Koretz, R. L. & Liu, J. P., 18 Sep 2017, In : Cochrane Database of Systematic Reviews. 9, p. CD012143

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Exercise for patients with major depression: a systematic review with meta-analysis and trial sequential analysis

    Krogh, J., Hjorthøj, C., Speyer, H., Gluud, C. & Nordentoft, M., 18 Sep 2017, In : B M J Open. 7, 9, p. e014820

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Specific barriers to the conduct of randomised clinical trials on medical devices

    Neugebauer, E. A. M., Rath, A., Antoine, S-L., Eikermann, M., Seidel, D., Koenen, C., Jacobs, E., Pieper, D., Laville, M., Pitel, S., Martinho, C., Djurisic, S., Demotes-Mainard, J., Kubiak, C., Bertele', V., Jakobsen, J. C., Garattini, S. & Gluud, C., 13 Sep 2017, In : Trials. 18, 1, p. 427

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Evidence-based practice within nutrition: what are the barriers for improving the evidence and how can they be dealt with?

    Laville, M., Segrestin, B., Alligier, M., Ruano-Rodríguez, C., Serra-Majem, L., Hiesmayr, M., Schols, A. M. W. J., La Vecchia, C., Boirie, Y., Rath, A., Neugebauer, E. A. M., Garattini, S., Bertele', V., Kubiak, C., Demotes-Mainard, J., Jakobsen, J. C., Djurisic, S. & Gluud, C., 11 Sep 2017, In : Trials. 18, 1, p. 425

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    3-dimensional versus conventional laparoscopy for benign hysterectomy: protocol for a randomized clinical trial

    Hoffmann, E., Bennich, G., Larsen, C. R., Lindschou, J., Jakobsen, J. C. & Lassen, P. D., 7 Sep 2017, In : BMC Women's Health. 17, 1, p. 76

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Cerebral near-infrared spectroscopy monitoring for prevention of brain injury in very preterm infants

    Hyttel-Sorensen, S., Greisen, G., Als-Nielsen, B. & Gluud, C., 4 Sep 2017, In : Cochrane Database of Systematic Reviews. 9, p. CD011506

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Effects of hydroxyethyl starch 130/0.42 vs. Ringer's acetate on cytokine levels in severe sepsis

    Anthon, C. T., Müller, R. B., Haase, N., Hjortrup, P. B., Møller, K., Lange, T., Wetterslev, J. & Perner, A., Sep 2017, In : Acta Anaesthesiologica Scandinavica. 61, 8, p. 904-913

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Low vs. high haemoglobin trigger for transfusion in vascular surgery: protocol for a randomised trial

    Møller, A., Nielsen, H. B., Wetterslev, J., Pedersen, O. B., Hellemann, D. & Shahidi, S., Sep 2017, In : Acta Anaesthesiologica Scandinavica. 61, 8, p. 952-961 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Lower vs. higher fluid volumes in sepsis-protocol for a systematic review with meta-analysis

    Meyhoff, T. S., Møller, M. H., Hjortrup, P. B., Cronhjort, M., Perner, A. & Wetterslev, J., Sep 2017, In : Acta Anaesthesiologica Scandinavica. 61, 8, p. 942-951 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Drug-eluting stents versus bare-metal stents for acute coronary syndrome

    Feinberg, J., Nielsen, E. E., Greenhalgh, J., Hounsome, J., Sethi, N. J., Safi, S., Gluud, C. & Jakobsen, J. C., 23 Aug 2017, In : Cochrane Database of Systematic Reviews. 8, p. CD012481

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Barriers to the conduct of randomised clinical trials within all disease areas

    Djurisic, S., Rath, A., Gaber, S., Garattini, S., Bertele', V., Ngwabyt, S-N., Hivert, V., Neugebauer, E. A. M., Laville, M., Hiesmayr, M., Demotes-Mainard, J., Kubiak, C., Jakobsen, J. C. & Gluud, C., 1 Aug 2017, In : Trials. 18, 1, p. 360

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Dysglycemia, Glycemic Variability, and Outcome After Cardiac Arrest and Temperature Management at 33°C and 36°C

    Borgquist, O., Wise, M. P., Nielsen, N., Al-Subaie, N., Cranshaw, J., Cronberg, T., Glover, G., Hassager, C., Kjaergaard, J., Kuiper, M., Smid, O., Walden, A., Friberg, H. & TTM-Trial Investigators, Aug 2017, In : Critical Care Medicine. 45, 8, p. 1337-1343 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published
  50. Published
  51. Published
  52. Published

    Protein S100 as outcome predictor after out-of-hospital cardiac arrest and targeted temperature management at 33 °C and 36 °C

    Stammet, P., Dankiewicz, J., Nielsen, N., Fays, F., Collignon, O., Hassager, C., Wanscher, M., Undén, J., Wetterslev, J., Pellis, T., Aneman, A., Hovdenes, J., Wise, M. P., Gilson, G., Erlinge, D., Horn, J., Cronberg, T., Kuiper, M., Kjaergaard, J., Gasche, Y., Devaux, Y., Friberg, H. & Target Temperature Management after Out-of-Hospital Cardiac Arrest (TTM) trial investigators, 20 Jun 2017, In : Critical care (London, England). 21, 1, p. e153

    Research output: Contribution to journalJournal articleResearchpeer-review

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