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Copenhagen Trial Unit - a part of Copenhagen University Hospital
  1. 2020
  2. Published

    Sertraline in primary care: comments on the PANDA trial

    Hengartner, M. P., Plöderl, M., Braillon, A., Jakobsen, J. C. & Gluud, C., Jan 2020, In : The Lancet. Psychiatry. 7, 1, p. 17

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published
  4. Published

    Benefits and harm of paracetamol and ibuprofen in combination for postoperative pain: preplanned subgroup analyses of the multicenter randomized PANSAID trial

    Thybo, K. H., Hägi-Pedersen, D., Wetterslev, J., Dahl, J. B., Jakobsen, J. C., Pedersen, N. A., Jakobsen, K., Bülow, H. H., Ibsen, L., Overgaard, S. & Mathiesen, O., 2020, In : Acta Anaesthesiologica Scandinavica. 64, 2, p. 245-253

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published
  6. 2019
  7. Published

    Cerebral near-infrared spectroscopy monitoring versus treatment as usual for extremely preterm infants: a protocol for the SafeBoosC randomised clinical phase III trial

    Hansen, M. L., Pellicer, A., Gluud, C., Dempsey, E., Mintzer, J., Hyttel-Sørensen, S., Heuchan, A. M., Hagmann, C., Ergenekon, E., Dimitriou, G., Pichler, G., Naulaers, G., Cheng, G., Guimarães, H., Tkaczyk, J., Kreutzer, K. B., Fumagalli, M., Claris, O., Lemmers, P., Fredly, S., Szczapa, T., Austin, T., Jakobsen, J. C. & Greisen, G., 30 Dec 2019, In : Trials. 20, 1, p. 811

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Detailed statistical analysis plan for the SafeBoosC III trial: a multinational randomised clinical trial assessing treatment guided by cerebral oxygenation monitoring versus treatment as usual in extremely preterm infants

    Hansen, M. L., Pellicer, A., Gluud, C., Dempsey, E., Mintzer, J., Hyttel-Sorensen, S., Heuchan, A. M., Hagmann, C., Dimitriou, G., Pichler, G., Naulaers, G., Cheng, G., Vilan, A., Tkaczyk, J., Kreutzer, K. B., Fumagalli, M., Claris, O., Fredly, S., Szczapa, T., Lange, T., Jakobsen, J. C. & Greisen, G., 19 Dec 2019, In : Trials. 20, 1, p. 746

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Adding exercise to usual care in patients with hypertension, type 2 diabetes mellitus and/or cardiovascular disease: a protocol for a systematic review with meta-analysis and trial sequential analysis

    Rijal, A., Nielsen, E. E., Hemmingsen, B., Neupane, D., Gæde, P. H., Olsen, M. H. & Jakobsen, J. C., 17 Dec 2019, In : Systematic Reviews. 8, 1, p. 330

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Beta-blockers for suspected or diagnosed acute myocardial infarction

    Safi, S., Sethi, N. J., Nielsen, E. E., Feinberg, J., Jakobsen, J. C. & Gluud, C., 17 Dec 2019, In : Cochrane Database of Systematic Reviews. 12, p. CD012484

    Research output: Contribution to journalReviewResearchpeer-review

  11. E-pub ahead of print
  12. Published

    DEBATE-statistical analysis plans for observational studies

    Hiemstra, B., Keus, F., Wetterslev, J., Gluud, C. & van der Horst, I. C. C., 9 Dec 2019, In : BMC Medical Research Methodology. 19, 1, p. 233

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Antibiotic regimens for neonatal sepsis - a protocol for a systematic review with meta-analysis

    Korang, S. K., Safi, S., Gluud, C., Lausten-Thomsen, U. & Jakobsen, J. C., 5 Dec 2019, In : Systematic Reviews. 8, 1, p. 306

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published
  15. Published

    Low Dose Low-Molecular-Weight Heparin for Thrombosis Prophylaxis: Systematic Review with Meta-Analysis and Trial Sequential Analysis

    Eck, R. J., Bult, W., Wetterslev, J., Gans, R. O. B., Meijer, K., van der Horst, I. C. C. & Keus, F., 21 Nov 2019, In : Journal of Clinical Medicine. 8, 12, p. pii:E2039

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Xiao Chai Hu Tang, a herbal medicine, for chronic hepatitis B

    Kong, D. Z., Liang, N., Yang, G. L., Zhang, Z., Liu, Y., Li, J., Liu, X., Liang, S., Nikolova, D., Jakobsen, J. C., Gluud, C. & Liu, J., 7 Nov 2019, In : Cochrane Database of Systematic Reviews. 2019, 11

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Fever control interventions versus placebo, sham or no intervention in adults: a protocol for a systematic review with meta-analysis and Trial Sequential Analysis

    Sethi, N., Naqash, A. I., Nielsen, N. & Jakobsen, J. C., 3 Nov 2019, In : BMJ Open. 9, 11, p. e032389

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published
  19. Published

    Agents Intervening against Delirium in the Intensive Care Unit (AID-ICU) - Protocol for a randomised placebo-controlled trial of haloperidol in patients with delirium in the ICU

    Andersen-Ranberg, N., Poulsen, L. M., Perner, A., Wetterslev, J., Estrup, S., Lange, T., Ebdrup, B., Hästbacka, J., Morgan, M. P. G., Citerio, G., Zafrani, L., Caballero, J., Collet, M. O., Weber, S., Andreasen, A. S., Bestle, M., Pedersen, H. B. S., Hildebrandt, T., Thee, C., Jensen, T. B., Dey, N., Nielsen, L. G. & Mathiesen, O., Nov 2019, In : Acta Anaesthesiologica Scandinavica. 63, 10, p. 1426-1433 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Cannabinoids versus placebo or no intervention for pain: protocol for a systematic review with meta-analysis and trial sequential analysis

    Barakji, J. A., Korang, S. K., Feinberg, J., Maagard, M., Gluud, C., Mathiesen, O. & Jakobsen, J. C., 31 Oct 2019, In : BMJ Open. 9, 10, p. e031574

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The effects of adding angiotensin receptor neprilysin inhibitors to usual care in patients with heart failure: a protocol for a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis

    Nielsen, E. E., Feinberg, J., Raymond, I., Olsen, M. H., Steensgaard-Hansen, F. V. & Jakobsen, J. C., 31 Oct 2019, In : Systematic Reviews. 8, 1, p. 251

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. E-pub ahead of print

    Letter to the Editor: Glucocorticosteroids for alcoholic for alcoholic hepatitis

    Varganova, D., Pavlov, C. S., Nikolova, D., Gluud, C. & Casazza, G., 29 Oct 2019, In : Hepatology (Baltimore, Md.).

    Research output: Contribution to journalLetterResearchpeer-review

  23. Published
  24. E-pub ahead of print
  25. Published
  26. Published

    A difficulty with the DIFFMASK score is the difficult statistics - a reply

    Lundstrøm, L. H., Rosenstock, C. V., Wetterslev, J. & Nørskov, A. K., Oct 2019, In : Anaesthesia. 74, 10, p. 1338

    Research output: Contribution to journalLetterResearchpeer-review

  27. Published

    Pantoprazole in ICU patients at risk for gastrointestinal bleeding-1-year mortality in the SUP-ICU trial

    Marker, S., Krag, M., Perner, A., Wetterslev, J., Lange, T., Wise, M. P., Borthwick, M., Bendel, S., Keus, F., Guttormsen, A. B., Schefold, J. C., Rasmussen, B. S., Elkmann, T., Bestle, M., Arenkiel, B., Laake, J. H., Kamper, M. K., Lång, M., Pawlowicz-Dworzanska, M. B., Karlsson, S., Liisanantti, J., Dey, N., Knudsen, H., Granholm, A., SUP-ICU trial investigators & Møller, M. H., Oct 2019, In : Acta Anaesthesiologica Scandinavica. 63, 9, p. 1184-1190 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. E-pub ahead of print

    Should antidepressants be used for major depressive disorder?

    Jakobsen, J. C., Gluud, C. & Kirsch, I., 25 Sep 2019, In : BMJ Evidence-Based Medicine.

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published
  30. Published

    Outcomes of Prophylactic Pantoprazole in Adult Intensive Care Unit Patients Receiving Dialysis: Results of a Randomized Trial

    Schefold, J. C., Krag, M., Marker, S., Perner, A., Wetterslev, J., Wise, M. P., Borthwick, M., Bendel, S., Keus, F., Guttormsen, A. B., Lange, T., the SUP-ICU investigators & Møller, M. H., 3 Sep 2019, In : American Journal of Nephrology. 50, 4, p. 312-319 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Time to onset of gastrointestinal bleeding in the SUP-ICU trial: a preplanned substudy

    Granholm, A., Lange, T., Anthon, C. T., Marker, S., Krag, M., Meyhoff, T. S., Wise, M. P., Borthwick, M., Bendel, S., Keus, F., Guttormsen, A. B., Schefold, J. C., Wetterslev, J., Perner, A. & Møller, M. H., 23 Aug 2019, In : Acta Anaesthesiologica Scandinavica. 63, 10, p. 1346-1356

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Acupuncture for chronic hepatitis B

    Kong, D. Z., Liang, N., Yang, G. L., Zhang, Z., Liu, Y., Yang, Y., Liu, Y. X., Wang, Q. G., Zhang, F., Zhang, H. Y., Nikolova, D., Jakobsen, J. C., Gluud, C. & Liu, J., 22 Aug 2019, In : Cochrane Database of Systematic Reviews. 8, p. CD013107

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. E-pub ahead of print
  34. Published

    Exercise-Based Rehabilitation for Heart Failure: Cochrane Systematic Review, Meta-Analysis, and Trial Sequential Analysis

    Taylor, R. S., Long, L., Mordi, I. R., Madsen, M. T., Davies, E. J., Dalal, H., Rees, K., Singh, S. J., Gluud, C. & Zwisler, A-D., 1 Aug 2019, In : JACC. Heart failure. 7, 8, p. 691-705 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Clinical Examination for the Prediction of Mortality in the Critically Ill: The Simple Intensive Care Studies-I

    Hiemstra, B., Eck, R. J., Wiersema, R., Kaufmann, T., Koster, G., Scheeren, T. W. L., Snieder, H., Perner, A., Pettilä, V., Wetterslev, J., Keus, F. & van der Horst, I. C. C., 25 Jul 2019, In : Critical Care Medicine. 47, 10, p. 1301-1309

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Heterogeneity of treatment effect of stress ulcer prophylaxis in ICU patients: A secondary analysis protocol

    Granholm, A., Marker, S., Krag, M., Zampieri, F. G., Thorsen-Meyer, H-C., Kaas-Hansen, B. S., van der Horst, I. C. C., Lange, T., Wetterslev, J., Perner, A. & Møller, M. H., 18 Jul 2019, In : Acta Anaesthesiologica Scandinavica. 63, 9, p. 1251-1256

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Short-term versus long-term psychotherapy for adult psychiatric disorders: a protocol for a systematic review with meta-analysis and trial sequential analysis

    Juul, S., Poulsen, S., Lunn, S., Sørensen, P., Jakobsen, J. C. & Simonsen, S., 13 Jul 2019, In : Systematic Reviews. 8, 1, p. 169

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Storage time of red blood cells among ICU patients with septic shock

    Rygård, S. L., Grønlykke, L., Perner, A., Winkel, P., Lange, T., Holst, L. B., Johansson, P. I., Aneman, A., Brodersen, T., Laurén, E., Ullum, H. & Wetterslev, J., 8 Jul 2019, In : Acta Anaesthesiologica Scandinavica. 63, 10, p. 1366-1377

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Conservative versus Liberal fluid therapy in Septic Shock (CLASSIC) trial - protocol and statistical analysis plan

    Meyhoff, T. S., Hjortrup, P. B., Møller, M. H., Wetterslev, J., Lange, T., Kjaer, M-B. N., Jonsson, A. B., Hjortsø, C. J. S., Cronhjort, M., Laake, J. H., Jakob, S. M., Nalos, M., Pettilä, V., van der Horst, I., Ostermann, M., Mouncey, P., Rowan, K., Cecconi, M., Ferrer, R., Malbrain, M. L. N. G., Ahlstedt, C., Hoffmann, S., Bestle, M. H., Nebrich, L., Russell, L., Vang, M., Rasmussen, M. L., Sølling, C., Rasmussen, B. S., Brøchner, A. C. & Perner, A., 5 Jul 2019, In : Acta Anaesthesiologica Scandinavica. 63, 9, p. 1262-1271

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Total serum bile acids or serum bile acid profile, or both, for the diagnosis of intrahepatic cholestasis of pregnancy

    Manzotti, C., Casazza, G., Stimac, T., Nikolova, D. & Gluud, C., 5 Jul 2019, In : Cochrane Database of Systematic Reviews. 7, p. CD012546

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    Plasma expanders for people with cirrhosis and large ascites treated with abdominal paracentesis

    Simonetti, R. G., Perricone, G., Nikolova, D., Bjelakovic, G. & Gluud, C., 28 Jun 2019, In : Cochrane Database of Systematic Reviews. 6, p. CD004039

    Research output: Contribution to journalReviewResearchpeer-review

  42. Published
  43. Published

    Targeted hypothermia versus targeted Normothermia after out-of-hospital cardiac arrest (TTM2): A randomized clinical trial-Rationale and design

    Dankiewicz, J., Cronberg, T., Lilja, G., Jakobsen, J. C., Bělohlávek, J., Callaway, C., Cariou, A., Eastwood, G., Erlinge, D., Hovdenes, J., Joannidis, M., Kirkegaard, H., Kuiper, M., Levin, H., Morgan, M. P. G., Nichol, A. D., Nordberg, P., Oddo, M., Pelosi, P., Rylander, C., Saxena, M., Storm, C., Taccone, F., Ullén, S., Wise, M. P., Young, P., Friberg, H. & Nielsen, N., 26 Jun 2019, In : American Heart Journal. 217, p. 23-31 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Radix Sophorae flavescentis versus other drugs or herbs for chronic hepatitis B

    Liang, N., Kong, D. Z., Lu, C. L., Ma, S. S., Li, Y. Q., Nikolova, D., Jakobsen, J. C., Gluud, C. & Liu, J. P., 24 Jun 2019, In : Cochrane Database of Systematic Reviews. 6, p. CD013106

    Research output: Contribution to journalReviewResearchpeer-review

  45. Published

    Selective serotonin reuptake inhibitors are still harmful and ineffective. Responses to the comments by Hieronymus et al

    Kiran Kumar, K., Naqash Javaid, S., Janus Christian, J. & Christian, G., 24 Jun 2019, In : Acta Neuropsychiatrica. 31, 5, p. 276-284 28 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Social skills training for attention deficit hyperactivity disorder (ADHD) in children aged 5 to 18 years

    Storebø, O. J., Elmose Andersen, M., Skoog, M., Joost Hansen, S., Simonsen, E., Pedersen, N., Tendal, B., Callesen, H. E., Faltinsen, E. & Gluud, C., 21 Jun 2019, In : Cochrane Database of Systematic Reviews. 6, p. CD008223

    Research output: Contribution to journalReviewResearchpeer-review

  47. Published

    Apparently conclusive meta-analyses on interventions in critical care may be inconclusive - a meta-epidemiological study

    Koster, T. M., Wetterslev, J., Gluud, C., Jakobsen, J. C., Kaufmann, T., Eck, R. J., Koster, G., Hiemstra, B., van der Horst, I. C. C. & Keus, F., 11 Jun 2019, In : Journal of Clinical Epidemiology. 114, p. 1-10

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Power estimations for non-primary outcomes in randomised clinical trials

    Jakobsen, J. C., Ovesen, C., Winkel, P., Hilden, J., Gluud, C. & Wetterslev, J., 6 Jun 2019, In : BMJ Open. 9, 6, p. e027092

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Glucocorticosteroids for people with alcoholic hepatitis

    Pavlov, C. S., Varganova, D. L., Casazza, G., Tsochatzis, E., Nikolova, D. & Gluud, C., 9 Apr 2019, In : Cochrane Database of Systematic Reviews. 4, p. CD001511

    Research output: Contribution to journalReviewResearchpeer-review

  50. Published

    Short-term versus long-term mentalization-based therapy for outpatients with subthreshold or diagnosed borderline personality disorder: a protocol for a randomized clinical trial

    Juul, S., Lunn, S., Poulsen, S., Sørensen, P., Salimi, M., Jakobsen, J. C., Bateman, A. & Simonsen, S., 5 Apr 2019, In : Trials. 20, 1, p. 196

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Assessing assumptions for statistical analyses in randomised clinical trials

    Nielsen, E. E., Nørskov, A. K., Lange, T., Thabane, L., Wetterslev, J., Beyersmann, J., de Uña-Álvarez, J., Torri, V., Billot, L., Putter, H., Winkel, P., Gluud, C. & Jakobsen, J. C., 4 Apr 2019, In : BMJ Evidence-Based Medicine. 24, 5, p. 185-189

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Carotid endarterectomy with primary closure versus patch angioplasty in patients with symptomatic and significant stenosis: protocol for a systematic review with meta-analyses and trial sequential analysis of randomised clinical trials

    Marsman, M. S., Wetterslev, J., Jahrome, A. K., Gluud, C., Moll, F. L., Karimi, A., Keus, F. & Koning, G. G., 4 Apr 2019, In : BMJ Open. 9, 4, p. e026419

    Research output: Contribution to journalJournal articleResearchpeer-review

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