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Copenhagen Prospective Studies on Asthma in Childhood - a part of Copenhagen University Hospital

Copenhagen Prospective Studies on Asthma in Childhood

Organisational unit: Sub Unit

  1. 2019
  2. Published

    Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

    EGG Consortium, May 2019, In : Nature Genetics. 51, 5, p. 804-814 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. E-pub ahead of print
  4. Published

    A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria

    Ahluwalia, T. S., Schulz, C-A., Waage, J., Skaaby, T., Sandholm, N., van Zuydam, N., Charmet, R., Bork-Jensen, J., Almgren, P., Thuesen, B. H., Bedin, M., Brandslund, I., Christensen, C. K., Linneberg, A., Ahlqvist, E., Groop, P-H., Hadjadj, S., Tregouet, D-A., Jørgensen, M. E., Grarup, N., Pedersen, O., Simons, M., Groop, L., Orho-Melander, M., McCarthy, M. I., Melander, O., Rossing, P., Kilpeläinen, T. O. & Hansen, T., 1 Feb 2019, In : Diabetologia. 62, 2, p. 292-305 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Multiple Breath Washout for Diagnosing Asthma in Children

    Arianto, L. B. N., 29 Jan 2019

    Research output: Book/ReportPh.D. thesisResearch

  6. E-pub ahead of print
  7. Published

    Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

    UK10K Consortium, 21 Jan 2019, In : Nature Communications. 10, 1, p. 357

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published
  9. Published
  10. 2018
  11. E-pub ahead of print
  12. E-pub ahead of print

    Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis

    Hartwig, F. P., Davies, N. M., Horta, B. L., Ahluwalia, T. S., Bisgaard, H., Bønnelykke, K., Caspi, A., Moffitt, T. E., Poulton, R., Sajjad, A., Tiemeier, H. W., Dalmau-Bueno, A., Guxens, M., Bustamante, M., Santa-Marina, L., Parker, N., Paus, T., Pausova, Z., Lauritzen, L., Schnurr, T. M., Michaelsen, K. F., Hansen, T., Oddy, W., Pennell, C. E., Warrington, N. M., Davey Smith, G. & Victora, C. G., 11 Dec 2018, In : International Journal of Epidemiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Short- and long-term impacts of azithromycin treatment on the gut microbiota in children: A double-blind, randomized, placebo-controlled trial

    Wei, S., Mortensen, M. S., Stokholm, J., Brejnrod, A. D., Thorsen, J., Rasmussen, M. A., Trivedi, U., Bisgaard, H. & Sørensen, S. J., Dec 2018, In : EBioMedicine. 38, p. 265-272 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Data representations and -analyses of binary diary data in pursuit of stratifying children based on common childhood illnesses

    de Rooi, J., Nørgaard, S. K., Rasmussen, M. A., Bønnelykke, K., Bisgaard, H. & Smilde, A. K., 29 Nov 2018, In : PLoS One. 13, 11, p. e0207177

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. E-pub ahead of print
  16. Published

    Environmental grass pollen levels in utero and at birth and cord blood IgE: Analysis of three birth cohorts

    Susanto, N. H., Schoos, A-M. M., Standl, M., Lowe, A. J., Dharmage, S. C., Svanes, C., Salim, A., von Berg, A., Lehmann, I., Rasmussen, M. A., Werchan, M., Bergmann, K-C., Lodge, C., Abramson, M. J., Heinrich, J., Bisgaard, H. & Erbas, B., Oct 2018, In : Environment International. 119, p. 295-301 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Limited clinical value of exhaled volatile organic compound measurements in childhood asthma

    Fuglsbjerg, M. G., Rasmussen, M. A., Hansen, K. S., Smolinska, A., Dallinga, J. W., van Schooten, F-J., Stokholm, J., Bønnelykke, K., Bisgaard, H. & Chawes, B. L., Oct 2018, In : ERJ Open Research. 4, 4

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published
  19. Published

    Consortium-based genome-wide meta-analysis for childhood dental caries traits

    Haworth, S., Shungin, D., van der Tas, J. T., Vucic, S., Medina-Gomez, C., Yakimov, V., Feenstra, B., Shaffer, J. R., Lee, M. K., Standl, M., Thiering, E., Wang, C., Bønnelykke, K., Waage, J., Jessen, L. E., Nørrisgaard, P. E., Joro, R., Seppälä, I., Raitakari, O., Dudding, T., Grgic, O., Ongkosuwito, E., Vierola, A., Eloranta, A-M., West, N. X., Thomas, S. J., McNeil, D. W., Levy, S. M., Slayton, R., Nohr, E. A., Lehtimäki, T., Lakka, T., Bisgaard, H., Pennell, C., Kühnisch, J., Marazita, M. L., Melbye, M., Geller, F., Rivadeneira, F., Wolvius, E. B., Franks, P. W., Johansson, I. & Timpson, N. J., 1 Sep 2018, In : Human Molecular Genetics. 27, 17, p. 3113-3127 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

    23andMe Research Team, Sep 2018, In : Nature Genetics. 50, 9, p. 1343

    Research output: Contribution to journalJournal articleCommunication

  21. Published

    Gene editing in the context of an increasingly complex genome

    Blighe, K., DeDionisio, L., Christie, K. A., Chawes, B., Shareef, S., Kakouli-Duarte, T., Chao-Shern, C., Harding, V., Kelly, R. S., Castellano, L., Stebbing, J., Lasky-Su, J. A., Nesbit, M. A. & Moore, C. B. T., 8 Aug 2018, In : BMC Genomics. 19, 1, p. 595

    Research output: Contribution to journalReviewResearchpeer-review

  22. Published

    An Integrative Transcriptomic and Metabolomic Study of Lung Function in Children With Asthma

    Kelly, R. S., Chawes, B. L., Blighe, K., Virkud, Y. V., Croteau-Chonka, D. C., McGeachie, M. J., Clish, C. B., Bullock, K., Celedón, J. C., Weiss, S. T. & Lasky-Su, J. A., Aug 2018, In : Chest. 154, 2, p. 335-348 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

    23andMe Research Team, Aug 2018, In : Nature Genetics. 50, 8, p. 1072-1080 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Safety and efficacy of immunotherapy with the recombinant B-cell epitope-based grass pollen vaccine BM32

    Niederberger, V., Neubauer, A., Gevaert, P., Zidarn, M., Worm, M., Aberer, W., Malling, H. J., Pfaar, O., Klimek, L., Pfützner, W., Ring, J., Darsow, U., Novak, N., Gerth van Wijk, R., Eckl-Dorna, J., Focke-Tejkl, M., Weber, M., Müller, H-H., Klinger, J., Stolz, F., Breit, N., Henning, R. & Valenta, R., Aug 2018, In : The Journal of allergy and clinical immunology. 142, 2, p. 497-509.e9

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The Airway Microbiota in Childhood Asthma

    Thorsen, J. J. I., 6 Jul 2018

    Research output: Book/ReportPh.D. thesisResearch

  26. Published

    Prenatal Vitamin D Supplementation to Improve Health in Offspring

    Chawes, B., Bønnelykke, K. & Bisgaard, H., 1 Jul 2018, In : JAMA Pediatrics. 172, 7, p. 617-618 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published
  28. Published

    17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use

    Farzan, N., Vijverberg, S. J., Hernandez-Pacheco, N., Bel, E. H. D., Berce, V., Bønnelykke, K., Bisgaard, H., Burchard, E. G., Canino, G., Celedón, J. C., Chew, F. T., Chiang, W. C., Cloutier, M. M., Forno, E., Francis, B., Hawcutt, D. B., Herrera-Luis, E., Kabesch, M., Karimi, L., Melén, E., Mukhopadhyay, S., Merid, S. K., Palmer, C. N., Pino-Yanes, M., Pirmohamed, M., Potočnik, U., Repnik, K., Schieck, M., Sevelsted, A., Sio, Y. Y., Smyth, R. L., Soares, P., Söderhäll, C., Tantisira, K. G., Tavendale, R., Tse, S. M., Turner, S., Verhamme, K. M. & Maitland-van der Zee, A-H., 9 Jun 2018, In : Allergy. 73, 10, p. 2083-2088 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    NKG2D gene variation and susceptibility to viral bronchiolitis in childhood

    Pasanen, A., Karjalainen, M. K., Kummola, L., Waage, J., Bønnelykke, K., Ruotsalainen, M., Piippo-Savolainen, E., Goksör, E., Nuolivirta, K., Chawes, B., Vissing, N., Bisgaard, H., Jartti, T., Wennergren, G., Junttila, I., Hallman, M., Korppi, M. & Rämet, M., 9 Jun 2018, In : Pediatric Research. 84, p. 451-457 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Epidemiology and Risk Factors of Infection in Early Childhood

    Vissing, N. H., Chawes, B. L., Rasmussen, M. A. & Bisgaard, H., Jun 2018, In : Pediatrics. 141, 6, p. e:20170933 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Lung Function Trajectories in Children with Asthma

    Hallas, H. W., 28 May 2018

    Research output: Book/ReportPh.D. thesisResearch

  32. Published

    Cat exposure in early life decreases asthma risk from the 17q21 high-risk variant

    Stokholm, J., Chawes, B. L., Vissing, N., Bønnelykke, K. & Bisgaard, H., May 2018, In : The Journal of allergy and clinical immunology. 141, 5, p. 1598-1606 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    FeNO and Exercise Testing in Children at Risk of Asthma

    Schoos, A-M. M., Christiansen, C. F., Stokholm, J., Bønnelykke, K., Bisgaard, H. & Chawes, B. L., May 2018, In : The journal of allergy and clinical immunology. In practice. 6, 3, p. 855-862 8 p., e2.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Neonates colonized with pathogenic bacteria in the airways have a low-grade systemic inflammation

    Rahman Fink, N., Chawes, B. L., Thorsen, J., Stokholm, J., Krogfelt, K., Schjørring, S., Kragh, M., Bønnelykke, K., Brix, S. & Bisgaard, H., 9 Apr 2018, In : Allergy. 73, 11, p. 2150-2159 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    EAACI guidelines on allergen immunotherapy: Executive statement

    Muraro, A., Roberts, G., Halken, S., Agache, I., Angier, E., Fernandez-Rivas, M., Gerth van Wijk, R., Jutel, M., Lau, S., Pajno, G., Pfaar, O., Ryan, D., Sturm, G. J., van Ree, R., Varga, E-M., Bachert, C., Calderon, M., Canonica, G. W., Durham, S. R., Malling, H. J., Wahn, U. & Sheikh, A., Apr 2018, In : Allergy. 73, 4, p. 739-743 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Pathway discovery using transcriptomic profiles in adult-onset severe asthma

    Hekking, P-P., Loza, M. J., Pavlidis, S., de Meulder, B., Lefaudeux, D., Baribaud, F., Auffray, C., Wagener, A. H., Brinkman, P., Lutter, R., Bansal, A. T., Sousa, A. R., Bates, S. A., Pandis, Y., Fleming, L. J., Shaw, D. E., Fowler, S. J., Guo, Y., Meiser, A., Sun, K., Corfield, J., Howarth, P. H., Bel, E. H., Adcock, I. M., Chung, K. F., Djukanovic, R., Sterk, P. J., U-BIOPRED Study Group, Bisgaard, H., Vissing, N. H. & Bønnelykke, K., Apr 2018, In : The Journal of allergy and clinical immunology. 141, 4, p. 1280-1290 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    CDHR3 Genetics and Rhinovirus C Respiratory Illnesses

    Bønnelykke, K., Coleman, A. T., Evans, M. D., Thorsen, J., Waage, J., Vissing, N. H., Carlsson, C. J., Stokholm, J., Chawes, B. L., Jessen, L. E., Fischer, T. K., Bochkov, Y. A., Ober, C., Lemanske, R. F., Jackson, D. J., Gern, J. E. & Bisgaard, H., 1 Mar 2018, In : American Journal of Respiratory and Critical Care Medicine. 197, 5, p. 589-594 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Publisher Correction: Maturation of the gut microbiome and risk of asthma in childhood

    Stokholm, J., Blaser, M. J., Thorsen, J., Rasmussen, M. A., Waage, J., Vinding, R. K., Schoos, A-M. M., Kunøe, A., Fink, N. R., Chawes, B. L., Bønnelykke, K., Brejnrod, A. D., Mortensen, M. S., Al-Soud, W. A., Sørensen, S. J. & Bisgaard, H., 13 Feb 2018, In : Nature Communications. 9, 1, 704.

    Research output: Contribution to journalJournal articleCommunication

  39. Published

    Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

    Beaumont, R. N., Warrington, N. M., Cavadino, A., Tyrrell, J., Nodzenski, M., Horikoshi, M., Geller, F., Myhre, R., Richmond, R. C., Paternoster, L., Bradfield, J. P., Kreiner-Møller, E., Huikari, V., Metrustry, S., Lunetta, K. L., Painter, J. N., Hottenga, J-J., Allard, C., Barton, S. J., Espinosa, A., Marsh, J. A., Potter, C., Zhang, G., Ang, W., Berry, D. J., Bouchard, L., Das, S., Hakonarson, H., Heikkinen, J., Helgeland, Ø., Hocher, B., Hofman, A., Inskip, H. M., Jones, S. E., Kogevinas, M., Lind, P. A., Marullo, L., Medland, S. E., Murray, A., Murray, J. C., Njølstad, P. R., Nohr, E. A., Reichetzeder, C., Ring, S. M., Ruth, K. S., Santa-Marina, L., Scholtens, D. M., Sebert, S., Bisgaard, H., Sørensen, T. I. & Early Growth Genetics (EGG) Consortium, Feb 2018, In : Human Molecular Genetics. 27, 4, p. 742-756 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Safety and efficacy of tiotropium in children aged 1-5 years with persistent asthmatic symptoms: a randomised, double-blind, placebo-controlled trial

    Vrijlandt, E. J. L. E., El Azzi, G., Vandewalker, M., Rupp, N., Harper, T., Graham, L., Szefler, S. J., Moroni-Zentgraf, P., Sharma, A., Vulcu, S. D., Sigmund, R., Chawes, B., Engel, M. & Bisgaard, H., 17 Jan 2018, In : The Lancet Respiratory Medicine. p. 127-137 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Early life exposures and childhood growth

    Vinding, R. K., 11 Jan 2018

    Research output: Book/ReportPh.D. thesisResearch

  42. Published

    Maturation of the gut microbiome and risk of asthma in childhood

    Stokholm, J., Blaser, M. J., Thorsen, J., Rasmussen, M. A., Waage, J., Vinding, R. K., Schoos, A-M. M., Kunøe, A., Fink, N. R., Chawes, B. L., Bønnelykke, K., Brejnrod, A. D., Mortensen, M. S., Al-Soud, W. A., Sørensen, S. J. & Bisgaard, H., 10 Jan 2018, In : Nature Communications. 9, 1, p. 1-10 10 p., 141.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects

    Medina-Gomez, C., Kemp, J. P., Trajanoska, K., Luan, J., Chesi, A., Ahluwalia, T. S., Mook-Kanamori, D. O., Ham, A., Hartwig, F. P., Evans, D. S., Joro, R., Nedeljkovic, I., Zheng, H-F., Zhu, K., Atalay, M., Liu, C-T., Nethander, M., Broer, L., Porleifsson, G., Mullin, B. H., Handelman, S. K., Nalls, M. A., Jessen, L. E., Heppe, D. H. M., Richards, J. B., Wang, C., Chawes, B., Schraut, K. E., Amin, N., Wareham, N., Karasik, D., Van der Velde, N., Ikram, M. A., Zemel, B. S., Zhou, Y., Carlsson, C. J., Liu, Y., McGuigan, F. E., Boer, C. G., Bønnelykke, K., Ralston, S. H., Robbins, J. A., Walsh, J. P., Zillikens, M. C., Langenberg, C., Li-Gao, R., Williams, F. M. K., Harris, T. B., Akesson, K., Jackson, R. D., Sigurdsson, G., den Heijer, M., van der Eerden, B. C. J., van de Peppel, J., Spector, T. D., Pennell, C., Horta, B. L., Felix, J. F., Zhao, J. H., Wilson, S. G., de Mutsert, R., Bisgaard, H., Styrkársdóttir, U., Jaddoe, V. W., Orwoll, E., Lakka, T. A., Scott, R., Grant, S. F. A., Lorentzon, M., van Duijn, C. M., Wilson, J. F., Stefansson, K., Psaty, B. M., Kiel, D. P., Ohlsson, C., Ntzani, E., van Wijnen, A. J., Forgetta, V., Ghanbari, M., Logan, J. G., Williams, G. R., Bassett, J. H. D., Croucher, P. I., Evangelou, E., Uitterlinden, A. G., Ackert-Bicknell, C. L., Tobias, J. H., Evans, D. M. & Rivadeneira, F., 4 Jan 2018, In : American Journal of Human Genetics. 102, 1, p. 88-102 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Budesonide/formoterol maintenance and reliever therapy in adolescent patients with asthma

    Jorup, C., Lythgoe, D. & Bisgaard, H., Jan 2018, In : European Respiratory Journal. 51, 1, p. 1-13 13 p., 1701688.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

    Demenais, F., Margaritte-Jeannin, P., Barnes, K. C., Cookson, W. O. C., Altmüller, J., Ang, W., Barr, R. G., Beaty, T. H., Becker, A. B., Beilby, J., Bisgaard, H., Bjornsdottir, U. S., Bleecker, E., Bønnelykke, K., Boomsma, D. I., Bouzigon, E., Brightling, C. E., Brossard, M., Brusselle, G. G., Burchard, E., Burkart, K. M., Bush, A., Chan-Yeung, M., Chung, K. F., Couto Alves, A., Curtin, J. A., Custovic, A., Daley, D., de Jongste, J. C., Del-Rio-Navarro, B. E., Donohue, K. M., Duijts, L., Eng, C., Eriksson, J. G., Farrall, M., Fedorova, Y., Feenstra, B., Ferreira, M. A., Freidin, M. B., Gajdos, Z., Gauderman, J., Gehring, U., Geller, F., Genuneit, J., Gharib, S. A., Gilliland, F., Granell, R., Graves, P. E., Waage, J., Wareham, N. J. & Australian Asthma Genetics Consortium (AAGC) collaborators, Jan 2018, In : Nature Genetics. 50, 1, p. 42-53 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Vaginal seeding or vaginal microbial transfer from the mother to the cesarean born neonate: a commentary regarding clinical management

    Haahr, T., Glavind, J., Axelsson, P., Fischer, M. B., Bjurström, J. M., Andrésdóttir, G., Teilmann-Jørgensen, D., Bonde, U., Olsén Sørensen, N., Møller, M., Fuglsang, J., Ovesen, P. G., Petersen, J. P., Stokholm, J. & Clausen, T. D., 2018, In : BJOG : an international journal of obstetrics and gynaecology. 125, 5, p. 533-536

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. 2017
  48. Published

    Sensitization trajectories in childhood revealed by using a cluster analysis

    Schoos, A-M. M., Chawes, B. L., Melén, E., Bergström, A., Kull, I., Wickman, M., Bønnelykke, K., Bisgaard, H. & Rasmussen, M. A., Dec 2017, In : The Journal of allergy and clinical immunology. 140, 6, p. 1693-1699 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Perinatal Risk Factors for Childhood Asthma

    Sevelsted, A., 27 Nov 2017

    Research output: Book/ReportPh.D. thesisResearch

  50. Published

    Prenatal vitamin D supplementation reduces risk of asthma/recurrent wheeze in early childhood: A combined analysis of two randomized controlled trials

    Wolsk, H. M., Chawes, B. L., Litonjua, A. A., Hollis, B. W., Waage, J., Stokholm, J., Bønnelykke, K., Bisgaard, H. & Weiss, S. T., 27 Oct 2017, In : P L o S One. 12, 10, p. 1-15 15 p., e0186657.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published
  52. Published

    Cesarean Delivery and Body Mass Index at 6 Months and Into Childhood

    Vinding, R. K., Sejersen, T. S., Chawes, B. L., Bønnelykke, K., Buhl, T., Bisgaard, H. & Stokholm, J., Jun 2017, In : Pediatrics. 139, 6

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Precision allergy: Separate allergies to male and female dogs

    Schoos, A-M. M., Bønnelykke, K., Chawes, B. L., Stokholm, J., Bisgaard, H. & Kristensen, B., 14 May 2017, In : The journal of allergy and clinical immunology. In practice. 5, 6, p. 1754-1756 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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