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Center for Cancer Immune Therapy (CCIT) - a part of Copenhagen University Hospital

Center for Cancer Immune Therapy (CCIT)

Organisational unit: Research Unit

  1. 2021
  2. Published

    Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity

    Fougeroux, C., Goksøyr, L., Idorn, M., Soroka, V., Myeni, S. K., Dagil, R., Janitzek, C. M., Søgaard, M., Aves, K-L., Horsted, E. W., Erdoğan, S. M., Gustavsson, T., Dorosz, J., Clemmensen, S., Fredsgaard, L., Thrane, S., Vidal-Calvo, E. E., Khalifé, P., Hulen, T. M., Choudhary, S., Theisen, M., Singh, S. K., Garcia-Senosiain, A., Van Oosten, L., Pijlman, G., Hierzberger, B., Domeyer, T., Nalewajek, B. W., Strøbæk, A., Skrzypczak, M., Andersson, L. F., Buus, S., Buus, A. S., Christensen, J. P., Dalebout, T. J., Iversen, K., Harritshøj, L. H., Mordmüller, B., Ullum, H., Reinert, L. S., de Jongh, W. A., Kikkert, M., Paludan, S. R., Theander, T. G., Nielsen, M. A., Salanti, A. & Sander, A. F., Dec 2021, In: Nature Communications. 12, 1, p. 324 324.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. E-pub ahead of print

    Corrigendum to "Lynch syndrome-associated epithelial ovarian cancer and its immunological profile" [Gynecologic Oncology 162 (2021) 686-693]

    Rasmussen, M., Lim, K., Rambech, E., Andersen, M. H., Svane, I. M., Andersen, O., Jensen, L. H., Nilbert, M. & Therkildsen, C., 19 Nov 2021, (E-pub ahead of print) In: Gynecologic Oncology.

    Research output: Contribution to journalComment/debateResearchpeer-review

  4. Published

    Arginase 1-based immune modulatory vaccines induce anti-cancer immunity and synergize with anti-PD-1 checkpoint blockade

    Aaboe Jørgensen, M., Ugel, S., Hübbe, M. L., Carretta, M., Perez-Penco, M., Weis-Banke, S. E., Martinenaite, E., Kopp, K., Chapellier, M., Adamo, A., De Sanctis, F., Frusteri, C., Iezzi, M., Zocca, M-B., Madsen, D. H., Pedersen, A. W., Bronte, V. & Andersen, M. H., Nov 2021, In: Cancer immunology research. 9, 11, p. 1316-1326 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published
  6. Published

    Lynch syndrome-associated epithelial ovarian cancer and its immunological profile

    Rasmussen, M., Lim, K., Rambech, E., Andersen, M. H., Svane, I. M., Andersen, O., Jensen, L. H., Nilbert, M. & Therkildsen, C., 1 Sep 2021, In: Gynecologic Oncology. 162, 3, p. 686-693 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Midkine-A potential therapeutic target in melanoma

    Donia, M. & Jönsson, G., Sep 2021, In: Pigment Cell & Melanoma Research. 34, 5, p. 834-835 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  8. Published
  9. Published

    Metastatic melanoma presenting with subacute sensory neuronopathy

    Holm-Yildiz, S., Crone, C., Borch, T. H. & Jeppesen, T. D., Aug 2021, In: Muscle & Nerve. 64, 2, p. E5-E6

    Research output: Contribution to journalLetterResearchpeer-review

  10. Published

    The Danish metastatic melanoma database (DAMMED): A nation-wide platform for quality assurance and research in real-world data on medical therapy in Danish melanoma patients

    Ellebaek, E., Svane, I. M., Schmidt, H., Haslund, C. A., Donia, M., Hoejberg, L., Ruhlmann, C., Guldbrandt, L. M., Køhler, U. H. & Bastholt, L., Aug 2021, In: Cancer epidemiology. 73, p. 101943 101943.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. E-pub ahead of print

    Transcriptomic signatures of tumors undergoing T cell attack

    Gokuldass, A., Schina, A., Lauss, M., Harbst, K., Chamberlain, C. A., Draghi, A., Westergaard, M. C. W., Nielsen, M., Papp, K., Sztupinszki, Z., Csabai, I., Svane, I. M., Szallasi, Z., Jönsson, G. & Donia, M., 17 Jul 2021, (E-pub ahead of print) In: Cancer Immunology and Immunotherapy.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. E-pub ahead of print
  13. Published
  14. Published

    The capacity of CD4+ Vγ9Vδ2 T cells to kill cancer cells correlates with co-expression of CD56

    Holmen Olofsson, G., Pedersen, S. R., Aehnlich, P., Svane, I. M., Idorn, M. & Thor Straten, P., Jul 2021, In: Cytotherapy. 23, 7, p. 582-589 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Vγ9Vδ2 T Cells Concurrently Kill Cancer Cells and Cross-Present Tumor Antigens

    Holmen Olofsson, G., Idorn, M., Carnaz Simões, A. M., Aehnlich, P., Skadborg, S. K., Noessner, E., Debets, R., Moser, B., Met, Ö. & Thor Straten, P., 2 Jun 2021, In: Frontiers in Immunology. 12, p. 645131 645131.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Loss of Ambra1 promotes melanoma growth and invasion

    Di Leo, L., Bodemeyer, V., Bosisio, F. M., Claps, G., Carretta, M., Rizza, S., Faienza, F., Frias, A., Khan, S., Bordi, M., Pacheco, M. P., Di Martino, J., Bravo-Cordero, J. J., Daniel, C. J., Sears, R. C., Donia, M., Madsen, D. H., Guldberg, P., Filomeni, G., Sauter, T., Robert, C., De Zio, D. & Cecconi, F., 5 May 2021, In: Nature Communications. 12, 1, p. 2550 2550.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Immune check point inhibitors are associated with a spectrum of cardiac events in patients with cancer

    D'Souza, M., Svane, I. M., Gislason, G. & Schou, M., 21 Apr 2021, In: European Heart Journal. 42, 16, p. 1636 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  18. Published
  19. Published

    Immune Cell Profiling of Peripheral Blood as Signature for Response During Checkpoint Inhibition Across Cancer Types

    Araujo B de Lima, V., Hansen, M., Spanggaard, I., Rohrberg, K., Reker Hadrup, S., Lassen, U. & Svane, I. M., 25 Mar 2021, In: Frontiers in Oncology. 11, p. 558248 558248.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    TAM Receptor Inhibition-Implications for Cancer and the Immune System

    Aehnlich, P., Powell, R. M., Peeters, M. J. W., Rahbech, A. & Thor Straten, P., 10 Mar 2021, In: Cancers. 13, 6, p. 1-16 16 p., 1195.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    The Thioredoxin-Interacting Protein TXNIP Is a Putative Tumour Suppressor in Cutaneous T-Cell Lymphoma

    Stolearenco, V., Levring, T. B., Nielsen, H. M., Lindahl, L., Fredholm, S., Kongsbak-Wismann, M., Willerslev-Olsen, A., Buus, T. B., Nastasi, C., Hu, T., Gluud, M., Côme, C. R. M., Krejsgaard, T., Iversen, L., Bonefeld, C. M., Grønbæk, K., Met, Ö., Woetmann, A., Ødum, N. & Geisler, C., Mar 2021, In: Dermatology. 237, 2, p. 283-290 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published
  23. Published

    Adrenergic Signaling in Immunotherapy of Cancer: Friend or Foe?

    Jensen, A. W. P., Carnaz Simões, A. M., Thor Straten, P. & Holmen Olofsson, G., Feb 2021, In: Cancers. 13, 3, p. 1-16 16 p., 394.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published
  25. Published

    Vaccination against PD-L1 with IO103 a Novel Immune Modulatory Vaccine in Basal Cell Carcinoma: A phase iia study

    Jørgensen, N. G., Kaae, J., Grauslund, J. H., Met, Ö., Nielsen, S. L., Pedersen, A. W., Svane, I. M., Ehrnrooth, E., Andersen, M. H., Zachariae, C. & Skov, L., Feb 2021, In: Cancers. 13, 4, p. 1-15 15 p., 911.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Neurological adverse effects of cancer therapy with checkpoint inhibitors

    Stenör, C., Ellebæk, E., El Mahdaoui, S. & Svane, I. M., 11 Jan 2021, In: Ugeskrift for Laeger. 183, 2

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2020
  28. Published

    Changes in the Tumor Immune Microenvironment during Disease Progression in Patients with Ovarian Cancer

    Westergaard, M. C. W., Milne, K., Pedersen, M., Hasselager, T., Olsen, L. R., Anglesio, M. S., Borch, T. H., Kennedy, M., Briggs, G., Ledoux, S., Kreuzinger, C., Decken, I. V. D., Donia, M., Castillo-Tong, D. C., Nelson, B. H. & Svane, I. M., 18 Dec 2020, In: Cancers. 12, 12

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    INDEL detection, the 'Achilles heel' of precise genome editing: a survey of methods for accurate profiling of gene editing induced indels

    Bennett, E. P., Petersen, B. L., Johansen, I. E., Niu, Y., Yang, Z., Chamberlain, C. A., Met, Ö., Wandall, H. H. & Frödin, M., 2 Dec 2020, In: Nucleic Acids Research. 48, 21, p. 11958-11981 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Author Correction: Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma

    Lauss, M., Donia, M., Harbst, K., Andersen, R., Mitra, S., Rosengren, F., Salim, M., Vallon-Christersson, J., Törngren, T., Kvist, A., Ringnér, M., Svane, I. M. & Jönsson, G., 1 Dec 2020, In: Nature Communications. 11, 1, p. 1714 1714.

    Research output: Contribution to journalComment/debateResearchpeer-review

  31. Published

    KEYNOTE-022 part 3: a randomized, double-blind, phase 2 study of pembrolizumab, dabrafenib, and trametinib in BRAF-mutant melanoma

    KEYNOTE-022 international team, Dec 2020, In: Journal for ImmunoTherapy of Cancer. 8, 2

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Qualitative Analysis of Tumor-Infiltrating Lymphocytes across Human Tumor Types Reveals a Higher Proportion of Bystander CD8+ T Cells in Non-Melanoma Cancers Compared to Melanoma

    Gokuldass, A., Draghi, A., Papp, K., Borch, T. H., Nielsen, M., Westergaard, M. C. W., Andersen, R., Schina, A., Bol, K. F., Chamberlain, C. A., Presti, M., Met, Ö., Harbst, K., Lauss, M., Soraggi, S., Csabai, I., Szállási, Z., Jönsson, G., Svane, I. M. & Donia, M., 12 Nov 2020, In: Cancers. 12, 11, p. 1-15 15 p., 3344.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published
  34. Published
  35. Published

    Cutaneous adverse reactions to anti-PD-1 treatment - a systematic review

    Simonsen, A. B., Kaae, J., Ellebaek Steensgaard, E., Svane, I. M. & Zachariae, C., 1 Nov 2020, In: Journal of the American Academy of Dermatology. 83, 5, p. 1415-1424 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  36. Published

    ESMO consensus conference recommendations on the management of locoregional melanoma: under the auspices of the ESMO Guidelines Committee

    Michielin, O., van Akkooi, A., Lorigan, P., Ascierto, P. A., Dummer, R., Robert, C., Arance, A., Blank, C. U., Chiarion Sileni, V., Donia, M., Faries, M. B., Gaudy-Marqueste, C., Gogas, H., Grob, J. J., Guckenberger, M., Haanen, J., Hayes, A. J., Hoeller, C., Lebbé, C., Lugowska, I., Mandalà, M., Márquez-Rodas, I., Nathan, P., Neyns, B., Olofsson Bagge, R., Puig, S., Rutkowski, P., Schilling, B., Sondak, V. K., Tawbi, H., Testori, A. & Keilholz, U., Nov 2020, In: Annals of Oncology. 31, 11, p. 1449-1461 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    ESMO consensus conference recommendations on the management of metastatic melanoma: under the auspices of the ESMO Guidelines Committee

    Keilholz, U., Ascierto, P. A., Dummer, R., Robert, C., Lorigan, P., van Akkooi, A., Arance, A., Blank, C. U., Chiarion Sileni, V., Donia, M., Faries, M. B., Gaudy-Marqueste, C., Gogas, H., Grob, J. J., Guckenberger, M., Haanen, J., Hayes, A. J., Hoeller, C., Lebbé, C., Lugowska, I., Mandalà, M., Márquez-Rodas, I., Nathan, P., Neyns, B., Olofsson Bagge, R., Puig, S., Rutkowski, P., Schilling, B., Sondak, V. K., Tawbi, H., Testori, A. & Michielin, O., Nov 2020, In: Annals of Oncology. 31, 11, p. 1435-1448 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published
  39. Published

    Vaccination against RhoC induces long-lasting immune responses in patients with prostate cancer: results from a phase I/II clinical trial

    Schuhmacher, J., Heidu, S., Balchen, T., Richardson, J. R., Schmeltz, C., Sonne, J., Schweiker, J., Rammensee, H-G., Thor Straten, P., Røder, M. A., Brasso, K. & Gouttefangeas, C., Nov 2020, In: Journal for ImmunoTherapy of Cancer. 8, 2

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Healthy Donors Harbor Memory T Cell Responses to RAS Neo-Antigens

    Holmström, M. O. & Andersen, M. H., 19 Oct 2020, In: Cancers. 12, 10, p. 1-16 16 p., 3045.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Granzyme B Degraded Type IV Collagen Products in Serum Identify Melanoma Patients Responding to Immune Checkpoint Blockade

    Jensen, C., Sinkeviciute, D., Madsen, D. H., Önnerfjord, P., Hansen, M., Schmidt, H., Karsdal, M. A., Svane, I. M. & Willumsen, N., 28 Sep 2020, In: Cancers. 12, 10

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Improved Progression-Free Long-Term Survival of a Nation-Wide Patient Population with Metastatic Melanoma

    Soerensen, A. V., Ellebaek, E., Bastholt, L., Schmidt, H., Donia, M. & Svane, I. M., 11 Sep 2020, In: Cancers. 12, 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Collagen Density Modulates the Immunosuppressive Functions of Macrophages

    Larsen, A. M. H., Kuczek, D. E., Kalvisa, A., Siersbæk, M. S., Thorseth, M-L., Johansen, A. Z., Carretta, M., Grøntved, L., Vang, O. & Madsen, D. H., 1 Sep 2020, In: Journal of immunology (Baltimore, Md. : 1950). 205, 5, p. 1461-1472 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published
  45. Published

    Escape from nonsense-mediated decay associates with anti-tumor immunogenicity

    Litchfield, K., Reading, J. L., Lim, E. L., Xu, H., Liu, P., Al-Bakir, M., Wong, Y. N. S., Rowan, A., Funt, S. A., Merghoub, T., Perkins, D., Lauss, M., Svane, I. M., Jönsson, G., Herrero, J., Larkin, J., Quezada, S. A., Hellmann, M. D., Turajlic, S. & Swanton, C., 30 Jul 2020, In: Nature Communications. 11, 1, p. 3800

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published
  47. Published

    Cancer Immune Therapy for Philadelphia Chromosome-Negative Chronic Myeloproliferative Neoplasms

    Holmström, M. O., Hasselbalch, H. C. & Andersen, M. H., 2 Jul 2020, In: Cancers. 12, 7, p. 1-21 21 p., 1763.

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published
  49. Published

    Peptide vaccination directed against IDO1-expressing immune cells elicits CD8+ and CD4+ T-cell-mediated antitumor immunity and enhanced anti-PD1 responses

    Dey, S., Sutanto-Ward, E., Kopp, K. L., DuHadaway, J., Mondal, A., Ghaban, D., Lecoq, I., Zocca, M-B., Merlo, L. M. F., Mandik-Nayak, L., Andersen, M. H., Pedersen, A. W. & Muller, A. J., Jul 2020, In: Journal for ImmunoTherapy of Cancer. 8, 2, 2020000605.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    T-Cell Gene Therapy in Cancer Immunotherapy: Why It Is No Longer Just CARs on The Road

    Crowther, M. D., Svane, I. M. & Met, Ö., 30 Jun 2020, In: Cells. 9, 7

    Research output: Contribution to journalReviewResearchpeer-review

  51. Published

    Development of an In Vitro Assay to Assess Pharmacological Compounds and Reversion of Tumor-Derived Immunosuppression of Dendritic Cells

    Andersen, M. M., Larsen, J., Hansen, M., Pedersen, A. E. & Gad, M., 24 Jun 2020, In: Immunological Investigations. p. 1-17 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer

    Kverneland, A. H., Pedersen, M., Westergaard, M. C. W., Nielsen, M., Borch, T. H., Olsen, L. R., Aasbjerg, G., Santegoets, S. J., van der Burg, S. H., Milne, K., Nelson, B. H., Met, Ö., Donia, M. & Svane, I. M., 2 Jun 2020, In: Oncotarget. 11, 22, p. 2092-2105 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 49550435