Research output per year
Research output per year
- 400 - 450 out of 587 results
Search results
-
2016
Targeting of cancer neoantigens with donor-derived T cell receptor repertoires
Strønen, E., Toebes, M., Kelderman, S., van Buuren, M. M., Yang, W., van Rooij, N., Donia, M., Böschen, M.-L., Lund-Johansen, F., Olweus, J. & Schumacher, T. N., 10 Jun 2016, In: Science. 352, 6291, p. 1337-41 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
350 Citations (Scopus) -
Targetless T cells in cancer immunotherapy
Thor Straten, P. & Garrido, F., 2016, In: Journal for ImmunoTherapy of Cancer. 4, 1, p. 23Research output: Contribution to journal › Comment/debate › Research › peer-review
24 Citations (Scopus) -
Taxane-based chemotherapy and dendritic cell therapy in metastatic castration-resistant prostate cancer
Kongsted, P., 2016, University of Copenhagen.Research output: Book/Report › Ph.D. thesis
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The CALR exon 9 mutations are shared neoantigens in patients with CALR mutant chronic myeloproliferative neoplasms
Holmström, M. O., Riley, C. H., Svane, I. M., Hasselbalch, H. C. & Andersen, M. H., Dec 2016, In: Leukemia. 30, 12, p. 2413-2416 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
57 Citations (Scopus) -
The controversial role of TNF in melanoma
Donia, M., Kjeldsen, J. W. & Svane, I. M., Apr 2016, In: OncoImmunology. 5, 4, p. e1107699Research output: Contribution to journal › Journal article › Research › peer-review
20 Citations (Scopus) -
The Danish Melanoma Database
Hölmich, L. R., Klausen, S., Spaun, E., Schmidt, G., Gad, D., Svane, I. M., Schmidt, H., Lorentzen, H. F. & Ibfelt, E. H., 25 Oct 2016, In: Clinical Epidemiology. 8, p. 543-548 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
22 Citations (Scopus) -
The expression of IL-21 is promoted by MEKK4 in malignant T cells and associated with increased progression risk in cutaneous T-cell lymphoma
Fredholm, S., Livinov, I., Mongan, N. P., Schiele, S., Willerslev-Olsen, A., Petersen, D. L., Krejsgaard, T., Sibbesen, N., Nastasi, C., Bonefeld, C. M., Persson, J. L., thor Straten, P., Andersen, M. H., Koralov, S. B., Wasik, M., Geisler, C., Sasseville, D., Woetmann, A. & Ødum, N., 20 Jan 2016, In: The Journal of investigative dermatology. 136, 4, p. 866-869Research output: Contribution to journal › Journal article › Research › peer-review
5 Citations (Scopus) -
Therapeutic Vaccination against A Modified Minimal Survivin Epitope Induces Functional CD4 T Cells That Recognize Survivin-Expressing Cells
Nitschke, N. J., Bjoern, J., Met, O., Svane, I. M. & Andersen, M. H., Sept 2016, In: Scandinavian Journal of Immunology. 84, 3, p. 191-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
7 Citations (Scopus) -
Transfection of Tumor-Infiltrating T Cells with mRNA Encoding CXCR2
Idorn, M., Thor Straten, P., Svane, I. M. & Met, Ö., 2016, In: Methods in molecular biology. 1428, p. 261-76 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
12 Citations (Scopus) -
Voluntary running suppreses tumor growth through epinephrine- and IL-6-dependent NK cell mobilization and redistribution
Pedersen, L., Idorn, M., Olofsson, G. H., Lauenborg, B. T., Nookaew, I., Hansen, R. H., Johannesen, H. H., Becker, J. C., Pedersen, K. S., Dethlefsen, C., Nielsen, J., Gehl, J., Pedersen, B. K., Straten, P. T. & Hojman, P., 2016, In: Cell Metabolism. 23, 3, p. 554-62Research output: Contribution to journal › Journal article › Research › peer-review
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Voluntary Running Suppresses Tumor Growth through Epinephrine- and IL-6-Dependent NK Cell Mobilization and Redistribution
Pedersen, L., Idorn, M., Olofsson, G. H., Lauenborg, B., Nookaew, I., Hansen, R. H., Johannesen, H. H., Becker, J. C., Pedersen, K. S., Dethlefsen, C., Nielsen, J., Gehl, J., Pedersen, B. K., Thor Straten, P. & Hojman, P., 8 Mar 2016, In: Cell Metabolism. 23, 3, p. 554-62 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2015
Aberrant Expression of MHC Class II in Melanoma Attracts Inflammatory Tumor-Specific CD4+ T- Cells, Which Dampen CD8+ T-cell Antitumor Reactivity
Donia, M., Andersen, R., Kjeldsen, J. W., Fagone, P., Ahmad, S. M., Nicoletti, F., Andersen, M. H., thor Straten, P. & Svane, I. M., 2015, In: Cancer Research. 75, 18, p. 3747-59 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
87 Citations (Scopus) -
Antibody Stabilization of Peptide-MHC Multimers Reveals Functional T Cells Bearing Extremely Low-Affinity TCRs
Tungatt, K., Bianchi, V., Crowther, M. D., Powell, W. E., Schauenburg, A. J., Trimby, A., Donia, M., Miles, J. J., Holland, C. J., Cole, D. K., Godkin, A. J., Peakman, M., thor Straten, P., Svane, I. M., Sewell, A. K. & Dolton, G., 1 Jan 2015, In: Journal of immunology (Baltimore, Md. : 1950). 194, 1, p. 463-74 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
48 Citations (Scopus) -
Broadening the repertoire of melanoma-associated T-cell epitopes
Mørch Frøsig, T., Lyngaa, R., Met, Ö., Larsen, S. K., Donia, M., Svane, I. M., thor Straten, P. & Hadrup, S. R., May 2015, In: Cancer immunology, immunotherapy. 64, 5, p. 609-20 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
8 Citations (Scopus) -
CD19-Chimeric Antigen Receptor T Cells for Treatment of Chronic Lymphocytic Leukaemia and Acute Lymphoblastic Leukaemia
Lorentzen, C. L. & thor Straten, P., Oct 2015, In: Scandinavian Journal of Immunology. 82, 4, p. 307-19 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
36 Citations (Scopus) -
CD4+/CD8+ double-positive T cells: more than just a developmental stage?
Overgaard, N. H., Jung, J.-W., Steptoe, R. J. & Wells, J. W., Jan 2015, In: Journal of Leukocyte Biology. 97, 1, p. 31-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
211 Citations (Scopus) -
Combined killing of cancer cells and cross presentation of tumor antigen by Vγ9Vδ2 T cells.
Olofsson, G. H., Idorn, M., Schenker, R., Nössner, E., Debets, R., Moser, B., Met, Ö. & thor, S. P., 2015, In: Journal for ImmunoTherapy of Cancer. 3, Issue Suppl 2Research output: Contribution to journal › Journal article › Research › peer-review
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Confinement dependent chemotaxis in two-photon polymerized linear migration constructs with highly definable concentration gradients
Hjortø, G. M., Olsen, M. H., Svane, I. M. & Larsen, N. B., Apr 2015, In: Biomedical Microdevices. 17, 2, p. 30Research output: Contribution to journal › Journal article › Research › peer-review
7 Citations (Scopus) -
Cryopreservation of MHC multimers: Recommendations for quality assurance in detection of antigen specific T cells
Hadrup, S. R., Maurer, D., Laske, K., Frøsig, T. M., Andersen, S. R., Britten, C. M., van der Burg, S. H., Walter, S. & Gouttefangeas, C., Jan 2015, In: Cytometry. Part A. 87, 1, p. 37-48 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
19 Citations (Scopus) -
Data analysis as a source of variability of the HLA-peptide multimer assay: from manual gating to automated recognition of cell clusters
Gouttefangeas, C., Chan, C., Attig, S., Køllgaard, T. M. S., Rammensee, H.-G., Stevanović, S., Wernet, D., thor Straten, P., Welters, M. J. P., Ottensmeier, C., van der Burg, S. H. & Britten, C. M., May 2015, In: Cancer immunology, immunotherapy. 64, 5, p. 585-98 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
17 Citations (Scopus) -
Design and validation of conditional ligands for HLA-B*08:01, HLA-B*15:01, HLA-B*35:01, and HLA-B*44:05
Frøsig, T. M., Yap, J., Seremet, T., Lyngaa, R., Svane, I. M., thor Straten, P., Heemskerk, M. H. M., Grotenbreg, G. M. & Hadrup, S. R., Oct 2015, In: Cytometry. Part A. 87, 10, p. 967-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
15 Citations (Scopus) -
Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin
Friis, S., Madsen, D. H. & Bugge, T. H., Feb 2015, In: Journal of Biological Chemistry. 291, 6, p. :2577-8Research output: Contribution to journal › Journal article › Research › peer-review
25 Citations (Scopus) -
Establishing the pig as a large animal model for vaccine development against human cancer
Overgaard, N. H., Mørch Frøsig, T., Welner, S., Rasmussen, M., Ilsøe, M. B., Sørensen, M. R., Andersen, M. H., Buus, S. & Jungersen, G., 2015, In: Frontiers in genetics. 6, p. 286Research output: Contribution to journal › Journal article › Research › peer-review
15 Citations (Scopus) -
Exercise suppresses tumor growth through epinephrine- and IL-6-dependent mobilization and redistribution of NK cells.
Pedersen, L., Idorn, M., Olofsson, G., Nookaew, I., Hansen, R., Johannesen, H., Becker, J., Lauenborg, B., Pedersen, K., Dethlefsen, C., Nielsen, J., Gehl, J., Pedersen, B., thor, S. P. & Hojman, P., 2015, In: Journal for ImmunoTherapy of Cancer. 3Research output: Contribution to journal › Journal article › Research › peer-review
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Expansion of circulating CD56(bright) natural killer cells in patients with JAK2-positive chronic myeloproliferative neoplasms during treatment with interferon-α
Riley, C. H., Hansen, M., Brimnes, M. K., Hasselbalch, H. C., Bjerrum, O. W., thor Straten, P., Svane, I. M. & Jensen, M. K., 2015, In: European Journal of Haematology. 94, 3, p. 227-34Research output: Contribution to journal › Journal article › Research › peer-review
41 Citations (Scopus) -
Immune Regulation by Self-Recognition: Novel Possibilities for Anticancer Immunotherapy
Andersen, M. H., Sept 2015, In: National Cancer Institute. Journal (Print). 107, 9Research output: Contribution to journal › Journal article › Research › peer-review
38 Citations (Scopus) -
Indoleamine 2,3-dioxygenase vaccination
Andersen, M. H. & Svane, I. M., Jan 2015, In: OncoImmunology. 4, 1, p. e983770Research output: Contribution to journal › Journal article › Research › peer-review
20 Citations (Scopus) -
Influence of acute glycaemic level on measures of myocardial infarction in non-diabetic pigs
Diemar, S. S., Sejling, A.-S., Iversen, K. K., Engstrøm, T., Honge, J. L., Tønder, N., Vejlstrup, N., Idorn, M., Ekstrøm, K., Pedersen-Bjergaard, U., Thorsteinsson, B. & Dalsgaard, M., Dec 2015, In: Scandinavian cardiovascular journal : SCJ. 49, 6, p. 376-82 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
7 Citations (Scopus) -
Ipilimumab in the treatment of metastatic malignant melanoma: Immunological correlates of treatment and combination therapy
Bjørn, J., 2015, Det Sundhedsvidenskabelige Institut, KU.Research output: Book/Report › Ph.D. thesis
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Low-dose prednisolone in first-line docetaxel for patients with metastatic castration-resistant prostate cancer: Is there a clinical benefit?
Kongsted, P., Svane, I. M., Lindberg, H., Daugaard, G. & Sengeløv, L., Nov 2015, In: Urologic Oncology. 33, 11, p. 494.e15-20Research output: Contribution to journal › Journal article › Research › peer-review
15 Citations (Scopus) -
Neuroprotective and anti-inflammatory mechanisms are activated early in Optic Neuritis
Tsakiri, A., Ravanidis, S., Lagoudaki, R., Poulatsidou, K.-N., Svane, I. M., Frederiksen, J. L. & Grigoriadis, N., 7 Jan 2015, In: Acta Neurologica Scandinavica. 131, 5, p. 305-12Research output: Contribution to journal › Journal article › Research › peer-review
9 Citations (Scopus) -
New developments in the management of advanced melanoma - role of pembrolizumab
Improta, G., Leone, I., Donia, M., Gieri, S., Pelosi, G. & Fraggetta, F., 2015, In: OncoTargets and Therapy. 8, p. 2535-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
15 Citations (Scopus) -
Oncogenic cancer/testis antigens: prime candidates for immunotherapy
Gjerstorff, M. F., Andersen, M. H. & Ditzel, H. J., 30 Jun 2015, In: Oncotarget. 6, 18, p. 15772-87 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
251 Citations (Scopus) -
Pre-Vaccination Frequencies of Th17 Cells Correlate with Vaccine-Induced T-Cell Responses to Survivin-Derived Peptide Epitopes
Køllgaard, T., Ugurel-Becker, S., Idorn, M., Andersen, M. H., Becker, J. C. & thor Straten, P., 2015, In: P L o S One. 10, 7, p. e0131934Research output: Contribution to journal › Journal article › Research › peer-review
10 Citations (Scopus) -
Reorienting the immune system in the treatment of cancer by using anti-PD-1 and anti-PD-L1 antibodies
Borch, T. H., Donia, M., Andersen, M. H. & Svane, I. M., Sept 2015, In: Drug Discovery Today. 20, 9, p. 1127-34 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
30 Citations (Scopus) -
Selective costimulation by IL-15R/IL-15, but not IL-2R/IL-2, allows the induction of high numbers of tumor-specific CD8+ T cells by human dendritic cells matured in conditions of acute inflammation
Hansen, M., Wieckowski, E., Svane, I., Edwards, R. P. & Kalinski, P., 2015, In: Journal for ImmunoTherapy of Cancer.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of short-chain fatty acids on human monocyte-derived dendritic cells
Nastasi, C., Candela, M., Bonefeld, C. M., Geisler, C., Hansen, M., Krejsgaard, T., Biagi, E., Andersen, M. H., Brigidi, P., Ødum, N., Litman, T. & Woetmann, A., 2015, In: Scientific Reports. 5, p. 16148Research output: Contribution to journal › Journal article › Research › peer-review
298 Citations (Scopus) -
The targeting of indoleamine 2,3 dioxygenase -mediated immune escape in cancer
Iversen, T. Z., Andersen, M. H. & Svane, I. M., Jan 2015, In: Basic & clinical pharmacology & toxicology. 116, 1, p. 19-24 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
28 Citations (Scopus) -
Thinking outside the gate: single-cell assessments in multiple dimensions
Kvistborg, P., Gouttefangeas, C., Aghaeepour, N., Cazaly, A., Chattopadhyay, P. K., Chan, C., Eckl, J., Finak, G., Hadrup, S. R., Maecker, H. T., Maurer, D., Mosmann, T., Qiu, P., Scheuermann, R. H., Welters, M. J. P., Ferrari, G., Brinkman, R. R. & Britten, C. M., 21 Apr 2015, In: Immunity. 42, 4, p. 591-2 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
54 Citations (Scopus) -
Tryptophan 2,3-dioxygenase (TDO)-reactive T cells differ in their functional characteristics in health and cancer
Hjortsø, M. D., Larsen, S. K., Kongsted, P., Met, Ö., Frøsig, T. M., Holmen Andersen, G., Ahmad, S. M., Svane, I. M., Becker, J. C., thor Straten, P. & Andersen, M. H., Jan 2015, In: OncoImmunology. 4, 1, p. e968480Research output: Contribution to journal › Journal article › Research › peer-review
27 Citations (Scopus) -
Tumor-infiltrating lymphocytes for the treatment of metastatic cancer
Geukes Foppen, M. H., Donia, M., Svane, I. M. & Haanen, J. B. A. G., Dec 2015, In: Molecular Oncology. 9, 10, p. 1918-35 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
90 Citations (Scopus) -
Tumor infiltrating lymphocyte therapy for ovarian cancer and renal cell carcinoma
Andersen, R., Donia, M., Westergaard, M. C. W., Pedersen, M., Hansen, M. & Svane, I. M., 2 Dec 2015, In: Human vaccines & immunotherapeutics. 11, 12, p. 2790-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
59 Citations (Scopus) -
2014
5-Azacytidine treatment sensitizes tumor cells to T-cell mediated cytotoxicity and modulates NK cells in patients with myeloid malignancies
Gang, A. O., Mørch Frøsig, T., Brimnes, M. K., Skou, R. B. L., Treppendahl, M. B., Grønbæk, K., Dufva, I. H., Straten, P. T. & Hadrup, S. R., 2014, In: Blood Cancer Journal. 4, p. e197Research output: Contribution to journal › Journal article › Research › peer-review
65 Citations (Scopus) -
Analysis of the implementation of tyrosine kinase and mTOR-inhibitor treatment of metastatic renal cell carcinoma in Denmark
Sørensen, A. V., 2014, University of Copenhagen.Research output: Book/Report › Ph.D. thesis
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Bioinformatics for cancer immunotherapy target discovery
Olsen, L. R., Campos, B., Barnkob, M. S., Winther, O., Brusic, V. & Andersen, M. H., 26 Oct 2014, In: Cancer immunology, immunotherapy. 63, 12, p. 1235-1249 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
24 Citations (Scopus) -
B-lymphoid tyrosine kinase (Blk) is an oncogene and a potential target for therapy with dasatinib in cutaneous T-cell lymphoma (CTCL)
Petersen, D. L., Krejsgaard, T., Berthelsen, J., Fredholm, S., Willerslev-Olsen, A., Sibbesen, N. A., Bonefeld, C. M., Andersen, M. H., Francavilla, C., Olsen, J. V., Hu, T., Zhang, M., Wasik, M. A., Geisler, C., Woetmann, A. & Odum, N., Oct 2014, In: Leukemia. 28, 10, p. 2109-12 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
36 Citations (Scopus) -
Cellular Immune Responses Towards Regulatory Cells
Larsen, S. K., 2014, University of Copenhagen.Research output: Book/Report › Ph.D. thesis
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Correlation between frequencies of blood monocytic myeloid-derived suppressor cells, regulatory T cells and negative prognostic markers in patients with castration-resistant metastatic prostate cancer
Idorn, M., Køllgaard, T., Kongsted, P., Sengeløv, L. & thor Straten, P., Nov 2014, In: Cancer immunology, immunotherapy. 63, 11, p. 1177-87 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
145 Citations (Scopus) -
Elucidating the immunological effects of 5Azacytidine treatment in patients with myelodysplastic syndrome and identifying new conditional ligands and T-cell epitopes of relevance in melanoma
Mørch Frøsig, T., 2014, University of Copenhagen.Research output: Book/Report › Ph.D. thesis
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Ex vivo‐induction of large numbers of tumor‐specific effector and memory T Cells for adoptive T cell therapies using antigen‐loaded DCs
Hansen, M., Wieckowski, E. & Kalinski, P., Feb 2014.Research output: Contribution to conference › Conference abstract for conference › Research