Research output per year
Research output per year
- 100 - 150 out of 587 results
Search results
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2022
Exploring therapeutic cancer vaccines in patients with malignant melanoma and prostate cancer
Mørk, S., 9 May 2022Research output: Book/Report › Ph.D. thesis
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Extended T-Cell Epitope Landscape in Merkel Cell Polyomavirus Large T and Small T Oncoproteins Identified Uniquely in Patients with Cancer
Hansen, U. K., Lyngaa, R., Ibrani, D., Church, C., Verhaegen, M., Dlugosz, A. A., Becker, J. C., Straten, P. T., Nghiem, P. & Hadrup, S. R., Jan 2022, In: The Journal of investigative dermatology. 142, 1, p. 239-243.e13Research output: Contribution to journal › Letter › peer-review
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Feasibility of Intratumoral Anti-PD1 as Treatment of Human Basal Cell Carcinoma: An Explorative Study with Adjuvant Ablative Fractional Laser
Omland, S. H., Ejlertsen, J. S., Krustrup, D., Christensen, R. L., Svane, I. M., Olesen, U. H. & Hædersdal, M., 25 Nov 2022, In: Cancers. 14, 23, 5815.Research output: Contribution to journal › Journal article › Research › peer-review
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Fibrotic activity quantified in serum by measurements of type III collagen pro-peptides can be used for prognosis across different solid tumor types
Willumsen, N., Jensen, C., Green, G., Nissen, N. I., Neely, J., Nelson, D. M., Pedersen, R. S., Frederiksen, P., Chen, I. M., Boisen, M. K., Johansen, A. Z., Madsen, D. H., Svane, I. M., Lipton, A., Leitzel, K., Ali, S. M., Erler, J. T., Hurkmans, D. P., Mathijssen, R. H. J. & Aerts, J. & 5 others, , 25 Mar 2022, In: Cellular and Molecular Life Sciences. 79, 4, p. 204 204.Research output: Contribution to journal › Review › peer-review
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High Intensity Aerobic exercise training and Immune cell Mobilization in patients with lung cancer (HI AIM)-a randomized controlled trial
Holmen Olofsson, G., Mikkelsen, M. K., Ragle, A.-M., Christiansen, A. B., Olsen, A. P., Heide-Ottosen, L., Horsted, C. B., Pedersen, C. M. S., Engell-Noerregaard, L., Lorentzen, T., Persson, G. F., Vinther, A., Nielsen, D. L. & Thor Straten, P., 5 Mar 2022, In: BMC Cancer. 22, 1, p. 246 246.Research output: Contribution to journal › Journal article › Research › peer-review
11 Citations (Scopus) -
Highly efficient PD-1-targeted CRISPR-Cas9 for tumor-infiltrating lymphocyte-based adoptive T cell therapy
Chamberlain, C. A., Bennett, E. P., Kverneland, A. H., Svane, I. M., Donia, M. & Met, Ö., 17 Mar 2022, In: Molecular therapy oncolytics. 24, p. 417-428 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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How Can the EU Beating Cancer Plan Help in Tackling Lung Cancer, Colorectal Cancer, Breast Cancer and Melanoma?
Horgan, D., Baird, A.-M., Middleton, M., Mihaylova, Z., Van Meerbeeck, J. P., Vogel-Claussen, J., Van Schil, P. E., Malvehy, J., Ascierto, P. A., Dube, F., Zaiac, M., Lal, J. A., Kamińska-Winciorek, G., Donia, M., André, T., Kozaric, M., Osterlund, P., Dumitrascu, D. L. & Bertolaccini, L., 25 Aug 2022, In: Healthcare (Basel, Switzerland). 10, 9, 1618.Research output: Contribution to journal › Journal article › Research › peer-review
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Hud, blod og lymfesystem
Hendel, H. W., Hougaard Chakera, A., Svane, I. M., Pedersen, L. M., Oturai, P. S., Jensen, M. R. & Glenthøj, A., 2022, Klinisk Nuklearmedicin. 3. udgave ed. Munksgaard , p. 187-220Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
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Identification, characterisation, and manipulation of tumour-reactive CD8+ T cells: For immunotherapeutic advancement
Chamberlain, C. A., 31 Aug 2022Research output: Book/Report › Ph.D. thesis
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Identification of Viral and Cancer epitopes using peptide:MHC Stability measurements
Lie-Andersen, O., 6 Oct 2022, University of Copenhagen.Research output: Book/Report › Ph.D. thesis
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IDO-vaccine ablates immune-suppressive myeloid populations and enhances anti-tumor effects independent of tumor cell IDO status
Nandre, R., Verma, V., Gaur, P., Patil, V., Yang, X., Ramlaoui, Z., Shobaki, N., Andersen, M. H., Pedersen, A. W., Zocca, M.-B., Mkrtichyan, M., Gupta, S. & Khleif, S. N., 3 May 2022, In: Cancer immunology research. 10, 5, p. 571-580 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
13 Citations (Scopus) -
Immune modulatory vaccines: the safe way to inflame the tumor microenvironment & guide anti-cancer immunotherapies
Andersen, M. H., 2022, In: Immuno-Oncology Insights. 3, 9, p. 401–407Research output: Contribution to journal › Journal article › Research › peer-review
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Ligand Identification for Orphan MHC-Agnostic T-Cell Receptors by Whole Genome CRISPR–Cas9 Screening
Crowther, M. D., Legut, M. & Sewell, A. K., 2022, Methods in Molecular Biology. Vol. 2574. p. 3-14 12 p. (Methods in Molecular Biology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Lynch syndrome-associated epithelial ovarian cancer and its immunological profile (vol 162, 686, 2021)
Rasmussen, M., Lim, K., Rambech, E., Andersen, M. H., Svane, I. M., Andersen, O., Jensen, L. H., Nilbert, M. & Therkildsen, C., Jan 2022, 1 p.Research output: Other contribution › Research
1 Citation (Scopus) -
Manufacture of adoptive cell therapies at academic cancer centers: scientific, safety and regulatory challenges
Saini, K. S., Svane, I. M., Juan, M., Barlesi, F. & André, F., Jan 2022, In: Annals of Oncology. 33, 1, p. 6-12 7 p.Research output: Contribution to journal › Editorial › peer-review
4 Citations (Scopus) -
Metabolic Fitness in T-cell Immunotherapy
Jensen, K. M., 21 Mar 2022, University of Copenhagen.Research output: Book/Report › Ph.D. thesis
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Mitochondrial respiration supports autophagy to provide stress resistance during quiescence
Magalhaes-Novais, S., Blecha, J., Naraine, R., Mikesova, J., Abaffy, P., Pecinova, A., Milosevic, M., Bohuslavova, R., Prochazka, J., Khan, S., Novotna, E., Sindelka, R., Machan, R., Dewerchin, M., Vlcak, E., Kalucka, J., Stemberkova Hubackova, S., Benda, A., Goveia, J. & Mracek, T. & 5 others, , Oct 2022, In: Autophagy. 18, 10, p. 2409-2426 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Modeling Metastatic Colonization in a Decellularized Organ Scaffold-Based Perfusion Bioreactor
Rafaeva, M., Horton, E. R., Jensen, A. R. D., Madsen, C. D., Reuten, R., Willacy, O., Brøchner, C. B., Jensen, T. H., Zornhagen, K. W., Crespo, M., Grønseth, D. S., Nielsen, S. R., Idorn, M., Straten, P. T., Rohrberg, K., Spanggaard, I., Højgaard, M., Lassen, U., Erler, J. T. & Mayorca-Guiliani, A. E., 5 Jan 2022, In: Advanced healthcare materials. 11, 1, 2100684.Research output: Contribution to journal › Journal article › Research › peer-review
12 Citations (Scopus) -
Neoantigen-reactive CD8+ T cells affect clinical outcome of adoptive cell therapy with tumor-infiltrating lymphocytes in melanoma
Kristensen, N. P., Heeke, C., Tvingsholm, S. A., Borch, A., Draghi, A., Crowther, M. D., Carri, I., Munk, K. K., Holm, J. S., Bjerregaard, A.-M., Bentzen, A. K., Marquard, A. M., Szallasi, Z., McGranahan, N., Andersen, R., Nielsen, M., Jönsson, G. B., Donia, M., Svane, I. M. & Hadrup, S. R., 18 Jan 2022, In: The Journal of clinical investigation. 132, 2, 150535.Research output: Contribution to journal › Journal article › Research › peer-review
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Patients With Myeloproliferative Neoplasms Harbor High Frequencies of CD8 T Cell-Platelet Aggregates Associated With T Cell Suppression
Carnaz Simões, A. M., Holmström, M. O., Aehnlich, P., Rahbech, A., Radziwon-Balicka, A., Zamora, C., Wirenfeldt Klausen, T., Skov, V., Kjær, L., Ellervik, C., Fassi, D. E., Vidal, S., Hasselbalch, H. C., Andersen, M. H. & Thor Straten, P., 2022, In: Frontiers in Immunology. 13, p. 866610 866610.Research output: Contribution to journal › Journal article › Research › peer-review
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Peptide vaccination activating Galectin-3-specific T cells offers a novel means to target Galectin-3-expressing cells in the tumor microenvironment
Bendtsen, S. K., Perez-Penco, M., Hübbe, M. L., Martinenaite, E., Orebo Holmström, M., Weis-Banke, S. E., Grønne Dahlager Jørgensen, N., Jørgensen, M. A., Munir Ahmad, S., Jensen, K. M., Friese, C., Lundsager, M. T., Johansen, A. Z., Carretta, M., Ødum, N., Met, Ö., Svane, I. M., Madsen, D. H. & Andersen, M. H., 27 Jan 2022, In: OncoImmunology. 11, 1, p. 2026020 2026020.Research output: Contribution to journal › Journal article › Research › peer-review
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Peptide vaccination in chronic lymphoproliferative malignancies: Targeting PDL1 and PDL2 in follicular lymphoma and chronic lymphocytic leukemia
Klausen, U., 11 Oct 2022, University of Copenhagen.Research output: Book/Report › Ph.D. thesis
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Personalized therapy with peptide-based neoantigen vaccine (EVX-01) including a novel adjuvant, CAF®09b, in patients with metastatic melanoma
Mørk, S. K., Kadivar, M., Bol, K. F., Draghi, A., Westergaard, M. C. W., Skadborg, S. K., Overgaard, N., Sørensen, A. B., Rasmussen, I. S., Andreasen, L. V., Yde, C. W., Trolle, T., Garde, C., Friis-Nielsen, J., Nørgaard, N., Christensen, D., Kringelum, J. V., Donia, M., Hadrup, S. R. & Svane, I. M., 10 Jan 2022, In: OncoImmunology. 11, 1, p. 2023255 2023255.Research output: Contribution to journal › Journal article › Research › peer-review
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Perspectives in Immunotherapy: meeting report from the Immunotherapy Bridge, December 1st-2nd, 2021
Ascierto, P. A., Avallone, A., Bhardwaj, N., Bifulco, C., Bracarda, S., Brody, J. D., Buonaguro, L., Demaria, S., Emens, L. A., Ferris, R. L., Galon, J., Khleif, S. N., Klebanoff, C. A., Laskowski, T., Melero, I., Paulos, C. M., Pignata, S., Ruella, M., Svane, I. M. & Taube, J. M. & 3 others, , 7 Jun 2022, In: Journal of Translational Medicine. 20, 1, p. 257 257.Research output: Contribution to journal › Journal article › Research › peer-review
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Production and Characterization of Peptide Antibodies to the C-Terminal of Frameshifted Calreticulin Associated with Myeloproliferative Diseases
Mughal, F. P., Bergmann, A. C., Huynh, H. U. B., Jørgensen, S. H., Mansha, I., Kesmez, M., Schürch, P. M., Theocharides, A. P. A., Hansen, P. R., Friis, T., Holmström, M. O., Ciplys, E., Slibinskas, R., Højrup, P., Houen, G. & Trier, N. H., 18 Jun 2022, In: International Journal of Molecular Sciences. 23, 12, 6803.Research output: Contribution to journal › Journal article › Research › peer-review
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Randomized Phase II Study of Nivolumab With or Without Ipilimumab Combined With Stereotactic Body Radiotherapy for Refractory Metastatic Pancreatic Cancer (CheckPAC)
Chen, I. M., Johansen, J. S., Theile, S., Hjaltelin, J. X., Novitski, S. I., Brunak, S., Hasselby, J. P., Willemoe, G. L., Lorentzen, T., Madsen, K., Jensen, B. V., Wilken, E. E., Geertsen, P., Behrens, C., Nolsoe, C., Hermann, K. L., Svane, I. M. & Nielsen, D., 20 Sept 2022, In: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40, 27, p. 3180-3189 10 p., JCO.21.02511.Research output: Contribution to journal › Journal article › Research › peer-review
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Real-world data on melanoma brain metastases and survival outcome
Pedersen, S., Møller, S., Donia, M., Persson, G. F., Svane, I. M. & Ellebaek, E., 1 Jun 2022, In: Melanoma Research. 32, 3, p. 173-182 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Relatlimab and Nivolumab versus Nivolumab in Untreated Advanced Melanoma
RELATIVITY-047 Investigators & Svane, I. M., 6 Jan 2022, In: The New England journal of medicine. 386, 1, p. 24-34 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Safety and efficacy of infliximab and corticosteroid therapy in checkpoint inhibitor-induced colitis
Dahl, E. K., Abed, O. K., Kjeldsen, J., Donia, M., Svane, I. M., Dige, A., Agnholt, J. S., Bjerrum, J. T. & Seidelin, J. B., Nov 2022, In: Alimentary Pharmacology and Therapeutics. 56, 9, p. 1370-1382 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
10 Citations (Scopus) -
Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast
Geldhof, V., de Rooij, L. P. M. H., Sokol, L., Amersfoort, J., De Schepper, M., Rohlenova, K., Hoste, G., Vanderstichele, A., Delsupehe, A.-M., Isnaldi, E., Dai, N., Taverna, F., Khan, S., Truong, A.-C. K., Teuwen, L.-A., Richard, F., Treps, L., Smeets, A., Nevelsteen, I. & Weynand, B. & 14 others, , 20 Sept 2022, In: Nature Communications. 13, 1, p. 5511 5511.Research output: Contribution to journal › Journal article › Research › peer-review
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TGFβ-derived immune modulatory vaccine: targeting the immunosuppressive and fibrotic tumor microenvironment in a murine model of pancreatic cancer
Perez-Penco, M., Weis-Banke, S. E., Schina, A., Siersbæk, M., Hübbe, M. L., Jørgensen, M. A., Lecoq, I., Lara De La Torre, L., Bendtsen, S. K., Martinenaite, E., Holmström, M. O., Madsen, D. H., Donia, M., Ødum, N., Grøntved, L. & Andersen, M. H., 6 Dec 2022, In: Journal for ImmunoTherapy of Cancer. 10, 12, e005491.Research output: Contribution to journal › Journal article › Research › peer-review
17 Citations (Scopus) -
The endocytic receptor uPARAP is a regulator of extracellular thrombospondin-1
Nørregaard, K. S., Jürgensen, H. J., Ingvarsen, S. Z., Heltberg, S. S., Hagensen, C. E., Gårdsvoll, H., Madsen, D. H., Jensen, O. N., Engelholm, L. H. & Behrendt, N., Aug 2022, In: Matrix biology : journal of the International Society for Matrix Biology. 111, p. 307-328 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
5 Citations (Scopus) -
Therapeutic cancer vaccination in patients with Philadelphia-chromosome negative myeloproliferative neoplasms
Grauslund, J. H., 23 Mar 2022Research output: Book/Report › Ph.D. thesis
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Tofacitinib and faecal microbiota transplantation in treating checkpoint inhibitor-induced enterocolitis: case report
Holmstroem, R. B., Dahl, E. K., Helms, M., Nielsen, H. V., Andersen, J. B., Bjerrum, J. T., Svane, I. M., Ellebaek, E. & Seidelin, J. B., Dec 2022, In: BMJ Open Gastroenterology. 9, 1, e000989.Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptomic signatures of tumors undergoing T cell attack
Gokuldass, A., Schina, A., Lauss, M., Harbst, K., Chamberlain, C. A., Draghi, A., Westergaard, M. C. W., Nielsen, M., Papp, K., Sztupinszki, Z., Csabai, I., Svane, I. M., Szallasi, Z., Jönsson, G. & Donia, M., Mar 2022, In: Cancer Immunology and Immunotherapy. 71, 3, p. 553-563 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
6 Citations (Scopus) -
Tumor-infiltrating lymphocytes for adoptive cell therapy: recent advances, challenges, and future directions
Granhøj, J. S., Witness Præst Jensen, A., Presti, M., Met, Ö., Svane, I. M. & Donia, M., May 2022, In: Expert Opinion on Biological Therapy. 22, 5, p. 627-641 15 p.Research output: Contribution to journal › Review › peer-review
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Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma
Rohaan, M. W., Borch, T. H., van den Berg, J. H., Met, Ö., Kessels, R., Geukes Foppen, M. H., Stoltenborg Granhøj, J., Nuijen, B., Nijenhuis, C., Jedema, I., van Zon, M., Scheij, S., Beijnen, J. H., Hansen, M., Voermans, C., Noringriis, I. M., Monberg, T. J., Holmstroem, R. B., Wever, L. D. V. & van Dijk, M. & 37 others, , 8 Dec 2022, In: The New England journal of medicine. 387, 23, p. 2113-2125 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Uncovering mediators of collagen degradation in the tumor microenvironment
Thorseth, M.-L., Carretta, M., Jensen, C., Mølgaard, K., Jürgensen, H. J., Engelholm, L. H., Behrendt, N., Willumsen, N. & Madsen, D. H., Feb 2022, In: Matrix Biology Plus. 13, p. 100101 100101.Research output: Contribution to journal › Journal article › Research › peer-review
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Vaccination against PD-L1
Jørgensen, N. G. D., 16 Jun 2022Research output: Book/Report › Ph.D. thesis
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YKL-40: A Cancer Target and Biomarker?
Johansen, A. Z., 29 Aug 2022Research output: Book/Report › Ph.D. thesis
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2021
A case report of immune checkpoint inhibitor-related steroid-refractory myocarditis and myasthenia gravis-like myositis treated with abatacept and mycophenolate mofetil
Jespersen, M. S., Fanø, S., Stenør, C. & Møller, A. K., Nov 2021, In: European Heart Journal - Case Reports. 5, 11, p. ytab342 ytab342.Research output: Contribution to journal › Journal article › Research › peer-review
29 Citations (Scopus) -
ACT Up TIL Now: The Evolution of Tumor-Infiltrating Lymphocytes in Adoptive Cell Therapy for the Treatment of Solid Tumors
Hulen, T. M., Chamberlain, C. A., Svane, I. M. & Met, O., 9 Jul 2021, In: Immuno. 1, 3, p. 194-211 17 p.Research output: Contribution to journal › Review › peer-review
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Adjuvant treatment for melanoma in clinical practice – Trial versus reality
de Meza, M. M., Ismail, R. K., Rauwerdink, D., van Not, O. J., van Breeschoten, J., Blokx, W. A. M., de Boer, A., van Dartel, M., Hilarius, D. L., Ellebaek, E., Bonenkamp, H. J., Blank, C. U., Aarts, M. J. B., van Akkooi, A. C. J., van den Berkmortel, F. W. P. J., Boers-Sonderen, M. J., de Groot, J. W. B., Haanen, J. B., Hospers, G. A. P. & Kapiteijn, E. W. & 8 others, , Nov 2021, In: European Journal of Cancer. 158, p. 234-245 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
19 Citations (Scopus) -
Adoptive cell therapy across cancer diagnoses
Kverneland, A., 11 Jun 2021, University of Copenhagen.Research output: Book/Report › Ph.D. thesis
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Adoptive cell therapy with tumor-infiltrating lymphocytes supported by checkpoint inhibition across multiple solid cancer types
Kverneland, A. H., Chamberlain, C. A., Borch, T. H., Nielsen, M., Mørk, S. K., Kjeldsen, J. W., Lorentzen, C. L., Jørgensen, L. P., Riis, L. B., Yde, C. W., Met, Ö., Donia, M. & Marie Svane, I., 4 Oct 2021, In: Journal for ImmunoTherapy of Cancer. 9, 10, e003499.Research output: Contribution to journal › Journal article › Research › peer-review
27 Citations (Scopus) -
Adrenergic Signaling in Immunotherapy of Cancer: Friend or Foe?
Jensen, A. W. P., Carnaz Simões, A. M., Thor Straten, P. & Holmen Olofsson, G., Feb 2021, In: Cancers. 13, 3, p. 1-16 16 p., 394.Research output: Contribution to journal › Review › peer-review
20 Citations (Scopus) -
Altered Antibody Response to Epstein-Barr Virus in Patients With Rheumatoid Arthritis and Healthy Subjects Predisposed to the Disease. A Twin Study
Svendsen, A. J., Westergaard, M. C. W., Draborg, A. H., Holst, R., Kyvik, K. O., Jakobsen, M. A., Junker, P. & Houen, G., 11 Mar 2021, In: Frontiers in Immunology. 12, 650713.Research output: Contribution to journal › Journal article › Research › peer-review
8 Citations (Scopus) -
An immunogenic first-in-human immune modulatory vaccine with PD-L1 and PD-L2 peptides is feasible and shows early signs of efficacy in follicular lymphoma
Klausen, U., Grønne Dahlager Jørgensen, N., Grauslund, J. H., Munir Ahmad, S., Gang, A. O., Martinenaite, E., Weis-Banke, S. E., Breinholt, M. F., Novotny, G. W., Kjeldsen, J. W., Orebo Holmström, M., Pedersen, L. B., Poulsen, C. B., Hansen, P. B., Met, Ö., Svane, I. M., Niemann, C. U., Pedersen, L. M. & Andersen, M. H., 2021, In: OncoImmunology. 10, 1, 1975889.Research output: Contribution to journal › Journal article › Research › peer-review
4 Citations (Scopus) -
A phase 1/2 trial of an immune-modulatory vaccine against IDO/PD-L1 in combination with nivolumab in metastatic melanoma
Kjeldsen, J. W., Lorentzen, C. L., Martinenaite, E., Ellebaek, E., Donia, M., Holmstroem, R. B., Klausen, T. W., Madsen, C. O., Ahmed, S. M., Weis-Banke, S. E., Holmström, M. O., Hendel, H. W., Ehrnrooth, E., Zocca, M. B., Pedersen, A. W., Andersen, M. H. & Svane, I. M., Dec 2021, In: Nature Medicine. 27, 12, p. 2212-2223 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
97 Citations (Scopus) -
Arginase 1-based immune modulatory vaccines induce anti-cancer immunity and synergize with anti-PD-1 checkpoint blockade
Aaboe Jørgensen, M., Ugel, S., Hübbe, M. L., Carretta, M., Perez-Penco, M., Weis-Banke, S. E., Martinenaite, E., Kopp, K., Chapellier, M., Adamo, A., De Sanctis, F., Frusteri, C., Iezzi, M., Zocca, M.-B., Madsen, D. H., Pedersen, A. W., Bronte, V. & Andersen, M. H., Nov 2021, In: Cancer immunology research. 9, 11, p. 1316-1326 11 p.Research output: Contribution to journal › Journal article › Research › peer-review