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Center for Cancer Immune Therapy (CCIT) - a part of Copenhagen University Hospital

Center for Cancer Immune Therapy (CCIT)

Organisational unit: Research Unit

  1. 2019
  2. Published

    Dickkopf-3 links HSF1 and YAP/TAZ signalling to control aggressive behaviours in cancer-associated fibroblasts

    Ferrari, N., Ranftl, R., Chicherova, I., Slaven, N. D., Moeendarbary, E., Farrugia, A. J., Lam, M., Semiannikova, M., Westergaard, M. C. W., Tchou, J., Magnani, L. & Calvo, F., 1 Dec 2019, In : Nature Communications. 10, 1, 130.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Tumour-reactive T cell subsets in the microenvironment of ovarian cancer

    Westergaard, M. C. W., Andersen, R., Chong, C., Kjeldsen, J. W., Pedersen, M., Friese, C., Hasselager, T., Lajer, H., Coukos, G., Bassani-Sternberg, M., Donia, M. & Svane, I. M., 19 Feb 2019, In : British Journal of Cancer. 120, 4, p. 424-434 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The real-world impact of modern treatments on the survival of patients with metastatic melanoma

    Donia, M., Ellebaek, E., Øllegaard, T. H., Duval, L., Aaby, J. B., Hoejberg, L., Køhler, U. H., Schmidt, H., Bastholt, L. & Svane, I. M., Feb 2019, In : European journal of cancer (Oxford, England : 1990). 108, p. 25-32 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published
  6. E-pub ahead of print

    HER2 CAR-T cells eradicate uveal melanoma and T cell therapy-resistant human melanoma in interleukin-2 (IL-2) transgenic NOD/SCID IL-2 receptor knockout mice

    Forsberg, E. M., Lindberg, M. F., Jespersen, H., Alsén, S., Olofsson Bagge, R., Donia, M., Svane, I. M., Nilsson, O., Ny, L., Nilsson, L. M. & Nilsson, J. A., 8 Jan 2019, In : Cancer Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins

    Jürgensen, H. J., Nørregaard, K. S., Sibree, M. M., Santoni-Rugiu, E., Madsen, D. H., Wassilew, K., Krustrup, D., Garred, P., Bugge, T. H., Engelholm, L. H. & Behrendt, N., 7 Jan 2019, In : Journal of Cell Biology. 218, 1, p. 333-349

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Acquired resistance to cancer immunotherapy

    Draghi, A., Chamberlain, C. A., Furness, A. & Donia, M., Jan 2019, In : Seminars in Immunopathology. 41, 1, p. 31-40 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    Actively personalized vaccination trial for newly diagnosed glioblastoma

    Hilf, N., Kuttruff-Coqui, S., Frenzel, K., Bukur, V., Stevanović, S., Gouttefangeas, C., Platten, M., Tabatabai, G., Dutoit, V., van der Burg, S. H., Thor Straten, P., Martínez-Ricarte, F., Ponsati, B., Okada, H., Lassen, U., Admon, A., Ottensmeier, C. H., Ulges, A., Kreiter, S., von Deimling, A., Skardelly, M., Migliorini, D., Kroep, J. R., Idorn, M., Rodon, J., Piró, J., Poulsen, H. S., Shraibman, B., McCann, K., Mendrzyk, R., Löwer, M., Stieglbauer, M., Britten, C. M., Capper, D., Welters, M. J. P., Sahuquillo, J., Kiesel, K., Derhovanessian, E., Rusch, E., Bunse, L., Song, C., Heesch, S., Wagner, C., Kemmer-Brück, A., Ludwig, J., Castle, J. C., Schoor, O., Tadmor, A. D., Green, E., Fritsche, J., Meyer, M., Pawlowski, N., Dorner, S., Hoffgaard, F., Rössler, B., Maurer, D., Weinschenk, T., Reinhardt, C., Huber, C., Rammensee, H-G., Singh-Jasuja, H., Sahin, U., Dietrich, P-Y. & Wick, W., Jan 2019, In : Nature. 565, 7738, p. 240-245 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Anti-cancer immunotherapy: breakthroughs and future strategies

    Andersen, M. H., Jan 2019, In : Seminars in Immunopathology. 41, 1, p. 1-3 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Cancer immune therapy for lymphoid malignancies: recent advances

    Klausen, U., Jørgensen, N. G. D., Grauslund, J. H., Holmström, M. O. & Andersen, M. H., Jan 2019, In : Seminars in Immunopathology. 41, 1, p. 111-124 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Cancer immune therapy for myeloid malignancies: present and future

    Holmström, M. O. & Hasselbalch, H. C., Jan 2019, In : Seminars in Immunopathology. 41, 1, p. 97-109 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published
  14. Published

    Principles of adoptive T cell therapy in cancer

    Met, Ö., Jensen, K. M., Chamberlain, C. A., Donia, M. & Svane, I. M., Jan 2019, In : Seminars in Immunopathology. 41, 1, p. 49-58 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    The T-win® technology: immune-modulating vaccines

    Andersen, M. H., Jan 2019, In : Seminars in Immunopathology. 41, 1, p. 87-95 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Immunoprofiles of colorectal cancer from Lynch syndrome

    Walkowska, J., Kallemose, T., Jönsson, G., Jönsson, M., Andersen, O., Andersen, M. H., Svane, I. M., Langkilde, A., Nilbert, M. & Therkildsen, C., 2019, In : OncoImmunology. 8, 1, p. e1515612

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2018
  18. E-pub ahead of print
  19. Published

    Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients

    Jensen, C., Madsen, D. H., Hansen, M., Schmidt, H., Svane, I. M., Karsdal, M. A. & Willumsen, N., 19 Dec 2018, In : Journal for ImmunoTherapy of Cancer. 6, 1, p. 152

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Genetically engineered cell factories produce glycoengineered vaccines that target antigen-presenting cells and reduce antigen-specific T-cell reactivity

    Mathiesen, C. B. K., Carlsson, M. C., Brand, S., Möller, S. R., Idorn, M., Thor Straten, P., Pedersen, A. E., Dabelsteen, S., Halim, A., Würtzen, P. A., Brimnes, J., Ipsen, H., Petersen, B. L. & Wandall, H. H., Dec 2018, In : The Journal of allergy and clinical immunology. 142, 6, p. 1983-1987 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published
  22. E-pub ahead of print

    Survival Outcomes in Patients With Previously Untreated BRAF Wild-Type Advanced Melanoma Treated With Nivolumab Therapy: Three-Year Follow-up of a Randomized Phase 3 Trial

    Ascierto, P. A., Long, G. V., Robert, C., Brady, B., Dutriaux, C., Di Giacomo, A. M., Mortier, L., Hassel, J. C., Rutkowski, P., McNeil, C., Kalinka-Warzocha, E., Savage, K. J., Hernberg, M. M., Lebbé, C., Charles, J., Mihalcioiu, C., Chiarion-Sileni, V., Mauch, C., Cognetti, F., Ny, L., Arance, A., Svane, I. M., Schadendorf, D., Gogas, H., Saci, A., Jiang, J., Rizzo, J. & Atkinson, V., 25 Oct 2018, In : JAMA Oncology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Chemokine Receptors and Exercise to Tackle the Inadequacy of T Cell Homing to the Tumor Site

    Idorn, M. & Thor Straten, P., 17 Aug 2018, In : Cells. 7, 8

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    SATB1 in Malignant T Cells

    Fredholm, S., Willerslev-Olsen, A., Met, Ö., Kubat, L., Gluud, M., Mathiasen, S. L., Friese, C., Blümel, E., Petersen, D. L., Hu, T., Nastasi, C., Lindahl, L. M., Buus, T. B., Krejsgaard, T., Wasik, M. A., Kopp, K. L., Koralov, S. B., Persson, J. L., Bonefeld, C. M., Geisler, C., Woetmann, A., Iversen, L., Becker, J. C. & Ødum, N., Aug 2018, In : The Journal of investigative dermatology. 138, 8, p. 1805-1815 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published
  26. Published

    Cancerimmunterapi

    Kjeldsen, J. W., Donia, M. & Svane, I. M., 21 May 2018, In : Ugeskrift for Laeger. 180, 21, p. 2-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Cancer immunotherapy in patients with brain metastases

    Caponnetto, S., Draghi, A., Borch, T. H., Nuti, M., Cortesi, E., Svane, I. M. & Donia, M., May 2018, In : Cancer immunology, immunotherapy : CII. 67, 5, p. 703-711 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin

    Woetmann, A., Alhede, M., Dabelsteen, S., Bjarnsholt, T., Rybtke, M., Nastasi, C., Krejsgaard, T., Andersen, M. H., Bonefeld, C. M., Geisler, C., Givskov, M. & Odum, N., 13 Apr 2018, In : Oncotarget. 9, 28, p. 19481-19489 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Peptide-MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations

    Rius, C., Attaf, M., Tungatt, K., Bianchi, V., Legut, M., Bovay, A., Donia, M., Thor Straten, P., Peakman, M., Svane, I. M., Ott, S., Connor, T., Szomolay, B., Dolton, G. & Sewell, A. K., 1 Apr 2018, In : Journal of immunology (Baltimore, Md. : 1950). 200, 7, p. 2263-2279 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Immunoregulatory antigens-novel targets for cancer immunotherapy

    Pedersen, A. W., Kopp, K. L., Andersen, M. H. & Zocca, M-B., Apr 2018, In : Chinese Clinical Oncology. 7, 2, p. 19

    Research output: Contribution to journalReviewResearchpeer-review

  31. Published

    The Balance Players of the Adaptive Immune System

    Andersen, M. H., 15 Mar 2018, In : Cancer Research. 78, 6, p. 1379-1382 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Adoptive cell therapy with tumor-infiltrating lymphocytes in patients with metastatic ovarian cancer: a pilot study

    Pedersen, M., Westergaard, M. C. W., Milne, K., Nielsen, M., Borch, T. H., Poulsen, L. G., Hendel, H. W., Kennedy, M., Briggs, G., Ledoux, S., Nøttrup, T. J., Andersen, P., Hasselager, T., Met, Ö., Nelson, B. H., Donia, M. & Svane, I. M., 2018, In : OncoImmunology. 7, 12, p. e1502905

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published
  34. Published

    Development of anti-drug antibodies is associated with shortened survival in patients with metastatic melanoma treated with ipilimumab

    Kverneland, A. H., Enevold, C., Donia, M., Bastholt, L., Svane, I. M. & Nielsen, C. H., 2018, In : OncoImmunology. 7, 5, p. e1424674

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published
  36. Published
  37. Published
  38. Published

    Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma

    Shraibman, B., Barnea, E., Kadosh, D. M., Haimovich, Y., Slobodin, G., Rosner, I., López-Larrea, C., Hilf, N., Kuttruff, S., Song, C., Britten, C., Castle, J., Kreiter, S., Frenzel, K., Tatagiba, M., Tabatabai, G., Dietrich, P-Y., Dutoit, V., Wick, W., Platten, M., Winkler, F., von Deimling, A., Kroep, J., Sahuquillo, J., Martinez-Ricarte, F., Rodon, J., Lassen, U., Ottensmeier, C., van der Burg, S. H., Thor Straten, P., Poulsen, H. S., Ponsati, B., Okada, H., Rammensee, H-G., Sahin, U., Singh, H. & Admon, A., 2018, In : Molecular & cellular proteomics : MCP. 17, 11, p. 2132-2145 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published
  40. Published
  41. Published
  42. Published
  43. Published

    The inhibitory checkpoint, PD-L2, is a target for effector T cells: Novel possibilities for immune therapy

    Ahmad, S. M., Martinenaite, E., Holmström, M., Jørgensen, M. A., Met, Ö., Nastasi, C., Klausen, U., Donia, M., Pedersen, L. M., Munksgaard, L., Ødum, N., Woetmann, A., Svane, I. M. & Andersen, M. H., 2018, In : OncoImmunology. 7, 2, p. e1390641

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published
  45. 2017
  46. Published

    Tumor-Associated Macrophages Derived from Circulating Inflammatory Monocytes Degrade Collagen through Cellular Uptake

    Madsen, D. H., Jürgensen, H. J., Siersbæk, M. S., Kuczek, D. E., Grey Cloud, L., Liu, S., Behrendt, N., Grøntved, L., Weigert, R. & Bugge, T. H., 26 Dec 2017, In : Cell Reports. 21, 13, p. 3662-3671 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published
  48. Published

    Butyrate and propionate inhibit antigen-specific CD8+ T cell activation by suppressing IL-12 production by antigen-presenting cells

    Nastasi, C., Fredholm, S., Willerslev-Olsen, A., Hansen, M., Bonefeld, C. M., Geisler, C., Andersen, M. H., Ødum, N. & Woetmann, A., 6 Nov 2017, In : Scientific Reports. 7, 1, p. 14516

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Mikromiljøet som med- og modspiller i B-celle-non-Hodgkin-lymfomer

    Klausen, U., Andersen, M. H. & Pedersen, L. M., 25 Sep 2017, In : Ugeskrift for læger. 26, 2017;179:V03170220, p. 2-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Predictors of responses to immune checkpoint blockade in advanced melanoma

    Jacquelot, N., Roberti, M. P., Enot, D. P., Rusakiewicz, S., Ternès, N., Jegou, S., Woods, D. M., Sodré, A. L., Hansen, M., Meirow, Y., Sade-Feldman, M., Burra, A., Kwek, S. S., Flament, C., Messaoudene, M., Duong, C. P. M., Chen, L., Kwon, B. S., Anderson, A. C., Kuchroo, V. K., Weide, B., Aubin, F., Borg, C., Dalle, S., Beatrix, O., Ayyoub, M., Balme, B., Tomasic, G., Di Giacomo, A. M., Maio, M., Schadendorf, D., Melero, I., Dréno, B., Khammari, A., Dummer, R., Levesque, M., Koguchi, Y., Fong, L., Lotem, M., Baniyash, M., Schmidt, H., Svane, I. M., Kroemer, G., Marabelle, A., Michiels, S., Cavalcanti, A., Smyth, M. J., Weber, J. S., Eggermont, A. M. & Zitvogel, L., 19 Sep 2017, In : Nature Communications. 8, 1, p. 592

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Sorted peripheral blood cells identify CALR mutations in B- and T-lymphocytes

    Kjaer, L., Holmström, M. O., Cordua, S., Andersen, M. H., Svane, I. M., Thomassen, M., Kruse, T. A., Pallisgaard, N., Skov, V. & Hasselbalch, H. C., 9 Aug 2017, In : Leukemia and Lymphoma. 59, 4, p. 973-977 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Anti-regulatory T cells

    Andersen, M. H., Apr 2017, In : Seminars in Immunopathology. 39, 3, p. 317-326

    Research output: Contribution to journalReviewResearchpeer-review

  53. Published

    Cancer immunotherapy in patients with preexisting autoimmune disorders

    Donia, M., Pedersen, M. & Svane, I. M., Apr 2017, In : Seminars in Immunopathology. 39, 3, p. 333-337 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

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