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Nature Genetics, 1061-4036

Journal

  1. 2021
  2. Published

    Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

    HUNT All-In Psychiatry, Jun 2021, In: Nature Genetics. 53, 6, p. 817-829 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Genetic analyses identify widespread sex-differential participation bias

    FinnGen Study, May 2021, In: Nature Genetics. 53, 5, p. 663-671 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

    LifeLines Cohort study, May 2021, In: Nature Genetics. 53, 5, p. 762

    Research output: Contribution to journalComment/debateResearchpeer-review

  5. Published

    Large-scale association analyses identify host factors influencing human gut microbiome composition

    Kurilshikov, A., Medina-Gomez, C., Bacigalupe, R., Radjabzadeh, D., Wang, J., Demirkan, A., Le Roy, C. I., Raygoza Garay, J. A., Finnicum, C. T., Liu, X., Zhernakova, D. V., Bonder, M. J., Hansen, T. H., Frost, F., Rühlemann, M. C., Turpin, W., Moon, J-Y., Kim, H-N., Lüll, K., Barkan, E., Shah, S. A., Fornage, M., Szopinska-Tokov, J., Wallen, Z. D., Borisevich, D., Agreus, L., Andreasson, A., Bang, C., Bedrani, L., Bell, J. T., Bisgaard, H., Boehnke, M., Boomsma, D. I., Burk, R. D., Claringbould, A., Croitoru, K., Davies, G. E., van Duijn, C. M., Duijts, L., Falony, G., Fu, J., van der Graaf, A., Hansen, T., Homuth, G., Hughes, D. A., Ijzerman, R. G., Jackson, M. A., Jaddoe, V. W. V., Joossens, M., Jørgensen, T., Keszthelyi, D., Knight, R., Laakso, M., Laudes, M., Launer, L. J., Lieb, W., Lusis, A. J., Masclee, A. A. M., Moll, H. A., Mujagic, Z., Qibin, Q., Rothschild, D., Shin, H., Sørensen, S. J., Steves, C. J., Thorsen, J., Timpson, N. J., Tito, R. Y., Vieira-Silva, S., Völker, U., Völzke, H., Võsa, U., Wade, K. H., Walter, S., Watanabe, K., Weiss, S., Weiss, F. U., Weissbrod, O., Westra, H-J., Willemsen, G., Payami, H., Jonkers, D. M. A. E., Arias Vasquez, A., de Geus, E. J. C., Meyer, K. A., Stokholm, J., Segal, E., Org, E., Wijmenga, C., Kim, H-L., Kaplan, R. C., Spector, T. D., Uitterlinden, A. G., Rivadeneira, F., Franke, A., Lerch, M. M., Franke, L., Sanna, S., D'Amato, M., Pedersen, O., Paterson, A. D., Kraaij, R., Raes, J. & Zhernakova, A., Feb 2021, In: Nature Genetics. 53, 2, p. 156-165 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

    Conti, D. V., Darst, B. F., Moss, L. C., Saunders, E. J., Sheng, X., Chou, A., Schumacher, F. R., Olama, A. A. A., Benlloch, S., Dadaev, T., Brook, M. N., Sahimi, A., Hoffmann, T. J., Takahashi, A., Matsuda, K., Momozawa, Y., Fujita, M., Muir, K., Lophatananon, A., Wan, P., Le Marchand, L., Wilkens, L. R., Stevens, V. L., Gapstur, S. M., Carter, B. D., Schleutker, J., Tammela, T. L. J., Sipeky, C., Auvinen, A., Giles, G. G., Southey, M. C., MacInnis, R. J., Cybulski, C., Wokołorczyk, D., Lubiński, J., Neal, D. E., Donovan, J. L., Hamdy, F. C., Martin, R. M., Nordestgaard, B. G., Nielsen, S. F., Weischer, M., Bojesen, S. E., Røder, M. A., Iversen, P., Batra, J., Chambers, S., Moya, L., Horvath, L., Clements, J. A., Tilley, W., Risbridger, G. P., Gronberg, H., Aly, M., Szulkin, R., Eklund, M., Nordström, T., Pashayan, N., Dunning, A. M., Ghoussaini, M., Travis, R. C., Key, T. J., Riboli, E., Park, J. Y., Sellers, T. A., Lin, H-Y., Albanes, D., Weinstein, S. J., Mucci, L. A., Giovannucci, E., Lindstrom, S., Kraft, P., Hunter, D. J., Penney, K. L., Turman, C., Tangen, C. M., Goodman, P. J., Thompson, I. M., Hamilton, R. J., Fleshner, N. E., Finelli, A., Parent, M-É., Stanford, J. L., Ostrander, E. A., Geybels, M. S., Koutros, S., Freeman, L. E. B., Stampfer, M., Wolk, A., Håkansson, N., Andriole, G. L., Hoover, R. N., Machiela, M. J., Sørensen, K. D., Borre, M., Blot, W. J., Zheng, W., Yeboah, E. D., Mensah, J. E., Lu, Y-J., Zhang, H-W., Feng, N., Mao, X., Wu, Y., Zhao, S-C., Sun, Z., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., West, C. M. L., Burnet, N., Barnett, G., Maier, C., Schnoeller, T., Luedeke, M., Kibel, A. S., Drake, B. F., Cussenot, O., Cancel-Tassin, G., Menegaux, F., Truong, T., Koudou, Y. A., John, E. M., Grindedal, E. M., Maehle, L., Khaw, K-T., Ingles, S. A., Stern, M. C., Vega, A., Gómez-Caamaño, A., Fachal, L., Rosenstein, B. S., Kerns, S. L., Ostrer, H., Teixeira, M. R., Paulo, P., Brandão, A., Watya, S., Lubwama, A., Bensen, J. T., Fontham, E. T. H., Mohler, J., Taylor, J. A., Kogevinas, M., Llorca, J., Castaño-Vinyals, G., Cannon-Albright, L., Teerlink, C. C., Huff, C. D., Strom, S. S., Multigner, L., Blanchet, P., Brureau, L., Kaneva, R., Slavov, C., Mitev, V., Leach, R. J., Weaver, B., Brenner, H., Cuk, K., Holleczek, B., Saum, K-U., Klein, E. A., Hsing, A. W., Kittles, R. A., Murphy, A. B., Logothetis, C. J., Kim, J., Neuhausen, S. L., Steele, L., Ding, Y. C., Isaacs, W. B., Nemesure, B., Hennis, A. J. M., Carpten, J., Pandha, H., Michael, A., De Ruyck, K., De Meerleer, G., Ost, P., Xu, J., Razack, A., Lim, J., Teo, S-H., Newcomb, L. F., Lin, D. W., Fowke, J. H., Neslund-Dudas, C., Rybicki, B. A., Gamulin, M., Lessel, D., Kulis, T., Usmani, N., Singhal, S., Parliament, M., Claessens, F., Joniau, S., Van den Broeck, T., Gago-Dominguez, M., Castelao, J. E., Martinez, M. E., Larkin, S., Townsend, P. A., Aukim-Hastie, C., Bush, W. S., Aldrich, M. C., Crawford, D. C., Srivastava, S., Cullen, J. C., Petrovics, G., Casey, G., Roobol, M. J., Jenster, G., van Schaik, R. H. N., Hu, J. J., Sanderson, M., Varma, R., McKean-Cowdin, R., Torres, M., Mancuso, N., Berndt, S. I., Van Den Eeden, S. K., Easton, D. F., Chanock, S. J., Cook, M. B., Wiklund, F., Nakagawa, H., Witte, J. S., Eeles, R. A., Kote-Jarai, Z. & Haiman, C. A., Jan 2021, In: Nature Genetics. 53, 1, p. 65-75 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2020
  8. Published

    Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

    kConFab Investigators, Jun 2020, In: Nature Genetics. 52, 6, p. 572-581 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease

    Eating Disorders Working Group of the Psychiatric Genomics Consortium, International Headache Genetics Consortium & 23andMe Research Team, May 2020, In: Nature Genetics. 52, 5, p. 482-493 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

    Cortés-Ciriano, I., Lee, J. J-K., Xi, R., Jain, D., Jung, Y. L., Yang, L., Gordenin, D., Klimczak, L. J., Zhang, C-Z., Pellman, D. S., Park, P. J., PCAWG-Structural Variation Working Group & Weischenfeldt, J., Mar 2020, In: Nature Genetics. 52, 3, p. 331-341

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

    PCAWG-Structural Variation Working Group & Weischenfeldt, J., Mar 2020, In: Nature Genetics. 52, 3, p. 294-305 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

    PCAWG-Structural Variation Working Group & Weischenfeldt, J., Mar 2020, In: Nature Genetics. 52, 3, p. 306-319 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

    GEMO Study Collaborators, Jan 2020, In: Nature Genetics. 52, 1, p. 56-73 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

    Surendran, P., Feofanova, E. V., Lahrouchi, N., Ntalla, I., Karthikeyan, S., Cook, J., Chen, L., Mifsud, B., Yao, C., Kraja, A. T., Cartwright, J. H., Hellwege, J. N., Giri, A., Tragante, V., Thorleifsson, G., Liu, D. J., Prins, B. P., Stewart, I. D., Cabrera, C. P., Eales, J. M., Akbarov, A., Auer, P. L., Bielak, L. F., Bis, J. C., Braithwaite, V. S., Brody, J. A., Daw, E. W., Warren, H. R., Drenos, F., Nielsen, S. F., Faul, J. D., Fauman, E. B., Fava, C., Ferreira, T., Foley, C. N., Franceschini, N., Gao, H., Giannakopoulou, O., Giulianini, F., Gudbjartsson, D. F., Guo, X., Harris, S. E., Havulinna, A. S., Bork-Jensen, J., Hansen, T., Jørgensen, M. E., Linneberg, A., Rasmussen, K. L., Skaaby, T., Nordestgaard, B. G. & LifeLines Cohort study, 2020, In: Nature Genetics. 52, 12, p. 1314-1332 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2019
  16. Published

    Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

    Anorexia Nervosa Genetics Initiative, Aug 2019, In: Nature Genetics. 51, 8, p. 1207-1214 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes

    Miguel-Escalada, I., Bonàs-Guarch, S., Cebola, I., Ponsa-Cobas, J., Mendieta-Esteban, J., Atla, G., Javierre, B. M., Rolando, D. M. Y., Farabella, I., Morgan, C. C., García-Hurtado, J., Beucher, A., Morán, I., Pasquali, L., Ramos-Rodríguez, M., Appel, E. V. R., Linneberg, A., Gjesing, A. P., Witte, D. R., Pedersen, O., Grarup, N., Ravassard, P., Torrents, D., Mercader, J. M., Piemonti, L., Berney, T., de Koning, E. J. P., Kerr-Conte, J., Pattou, F., Fedko, I. O., Groop, L., Prokopenko, I., Hansen, T., Marti-Renom, M. A., Fraser, P. & Ferrer, J., Jul 2019, In: Nature Genetics. 51, 7, p. 1137-1148 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The genetic evolution of metastatic uveal melanoma

    Shain, A. H., Bagger, M. M., Yu, R., Chang, D., Liu, S., Vemula, S., Weier, J. F., Wadt, K., Heegaard, S., Bastian, B. C. & Kiilgaard, J. F., Jul 2019, In: Nature Genetics. 51, 7, p. 1123-1130 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A catalog of genetic loci associated with kidney function from analyses of a million individuals

    LifeLines Cohort study, 1 Jun 2019, In: Nature Genetics. 51, 6, p. 957-972 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

    CommonMind Consortium & Werge, T. M., Jun 2019, In: Nature Genetics. 51, 6, p. 1068 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  21. Published

    Roadmap for a precision-medicine initiative in the Nordic region

    Njølstad, P. R., Andreassen, O. A., Brunak, S., Børglum, A. D., Dillner, J., Esko, T., Franks, P. W., Freimer, N., Groop, L., Heimer, H., Hougaard, D. M., Hovig, E., Hveem, K., Jalanko, A., Kaprio, J., Knudsen, G. P., Melbye, M., Metspalu, A., Mortensen, P. B., Palmgren, J., Palotie, A., Reed, W., Stefánsson, H., Stitziel, N. O., Sullivan, P. F., Thorsteinsdóttir, U., Vaudel, M., Vuorio, E., Werge, T., Stoltenberg, C. & Stefánsson, K., Jun 2019, In: Nature Genetics. 51, 6, p. 924-930 7 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  22. Published

    Genome-wide association study identifies 30 loci associated with bipolar disorder

    eQTLGen Consortium, May 2019, In: Nature Genetics. 51, 5, p. 793-803 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

    EGG Consortium, May 2019, In: Nature Genetics. 51, 5, p. 804-814 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

    CommonMind Consortium, Apr 2019, In: Nature Genetics. 51, 4, p. 659-674 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Osteogenesis depends on commissioning of a network of stem cell transcription factors that act as repressors of adipogenesis

    Rauch, A., Haakonsson, A. K., Madsen, J. G. S., Larsen, M., Forss, I., Madsen, M. R., Van Hauwaert, E. L., Wiwie, C., Jespersen, N. Z., Tencerova, M., Nielsen, R., Larsen, B. D., Röttger, R., Baumbach, J., Scheele, C., Kassem, M. & Mandrup, S., Apr 2019, In: Nature Genetics. 51, 4, p. 716-727 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

    CHD Exome+ Consortium, 1 Mar 2019, In: Nature Genetics. 51, 3, p. 452-469 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

    SpiroMeta Consortium, International COPD Genetics Consortium (Børge Nordestgaard) & Nordestgaard, B. G., Mar 2019, In: Nature Genetics. 51, 3, p. 494-505 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (Nature Genetics, (2018), 50, 7, (928-936), 10.1038/s41588-018-0142-8)

    Schumacher, F. R., Olama, A. A. A., Berndt, S. I., Benlloch, S., Ahmed, M., Saunders, E. J., Dadaev, T., Leongamornlert, D., Anokian, E., Cieza-Borrella, C., Goh, C., Brook, M. N., Sheng, X., Fachal, L., Dennis, J., Tyrer, J., Muir, K., Lophatananon, A., Stevens, V. L., Gapstur, S. M., Carter, B. D., Tangen, C. M., Goodman, P. J., Thompson, I. M., Batra, J., Chambers, S., Moya, L., Clements, J., Horvath, L., Tilley, W., Risbridger, G. P., Gronberg, H., Aly, M., Nordström, T., Pharoah, P., Pashayan, N., Schleutker, J., Tammela, T. L. J., Sipeky, C., Auvinen, A., Albanes, D., Weinstein, S., Wolk, A., Håkansson, N., Nordestgaard, B. G., Nielsen, S. F., Weischer, M., Bisbjerg, R., Røder, M. A., Iversen, P. & Profile Study, Feb 2019, In: Nature Genetics. 51, 2, p. 363 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  29. Published
  30. Published

    Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

    ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Jan 2019, In: Nature Genetics. 51, 1, p. 63-75 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Identification of common genetic risk variants for autism spectrum disorder

    Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, 2019, In: Nature Genetics. 51, 3, p. 431-444 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2018
  33. Published

    Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

    Mahajan, A., Taliun, D., Thurner, M., Robertson, N. R., Torres, J. M., Rayner, N. W., Payne, A. J., Steinthorsdottir, V., Scott, R. A., Grarup, N., Cook, J. P., Schmidt, E. M., Wuttke, M., Sarnowski, C., Mägi, R., Nano, J., Gieger, C., Trompet, S., Lecoeur, C., Preuss, M. H., Prins, B. P., Guo, X., Bielak, L. F., Below, J. E., Bowden, D. W., Chambers, J. C., Kim, Y. J., Ng, M. C. Y., Petty, L. E., Sim, X., Zhang, W., Bennett, A. J., Bork-Jensen, J., Brummett, C. M., Canouil, M., Ec Kardt, K-U., Fischer, K., Kardia, S. L. R., Kronenberg, F., Läll, K., Liu, C-T., Locke, A. E., Luan, J., Ntalla, I., Nylander, V., Schönherr, S., Schurmann, C., Yengo, L., Bottinger, E. P., Brandslund, I., Christensen, C., Dedoussis, G., Florez, J. C., Ford, I., Franco, O. H., Frayling, T. M., Giedraitis, V., Hackinger, S., Hattersley, A. T., Herder, C., Ikram, M. A., Ingelsson, M., Jørgensen, M. E., Jørgensen, T., Kriebel, J., Kuusisto, J., Ligthart, S., Lindgren, C. M., Linneberg, A., Lyssenko, V., Mamakou, V., Meitinger, T., Mohlke, K. L., Morris, A. D., Nadkarni, G., Pankow, J. S., Peters, A., Sattar, N., Stančáková, A., Strauch, K., Taylor, K. D., Thorand, B., Thorleifsson, G., Thorsteinsdottir, U., Tuomilehto, J., Witte, D. R., Dupuis, J., Peyser, P. A., Zeggini, E., Loos, R. J. F., Froguel, P., Ingelsson, E., Lind, L., Groop, L., Laakso, M., Collins, F. S., Jukema, J. W., Palmer, C. N. A., Grallert, H., Metspalu, A., Dehghan, A., Köttgen, A., Abecasis, G. R., Meigs, J. B., Rotter, J. I., Marchini, J., Pedersen, O., Hansen, T., Langenberg, C., Wareham, N. J., Stefansson, K., Gloyn, A. L., Morris, A. P., Boehnke, M. & McCarthy, M. I., Nov 2018, In: Nature Genetics. 50, p. 1505–1513 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation

    Basilicata, M. F., Bruel, A-L., Semplicio, G., Valsecchi, C. I. K., Aktaş, T., Duffourd, Y., Rumpf, T., Morton, J., Bache, I., Szymanski, W. G., Gilissen, C., Vanakker, O., Õunap, K., Mittler, G., van der Burgt, I., El Chehadeh, S., Cho, M. T., Pfundt, R., Tan, T. Y., Kirchhoff, M., Menten, B., Vergult, S., Lindstrom, K., Reis, A., Johnson, D. S., Fryer, A., McKay, V., Fisher, R. B., Thauvin-Robinet, C., Francis, D., Roscioli, T., Pajusalu, S., Radtke, K., Ganesh, J., Brunner, H. G., Wilson, M., Faivre, L., Kalscheuer, V. M., Thevenon, J., Akhtar, A. & DDD Study, Oct 2018, In: Nature Genetics. 50, 10, p. 1442-1451 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

    23andMe Research Team, Aug 2018, In: Nature Genetics. 50, 8, p. 1072-1080 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

    NBCS Collaborators, Jul 2018, In: Nature Genetics. 50, 7, p. 968-978 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

    Profile Study, 11 Jun 2018, In: Nature Genetics. 50, p. 928-36

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

    Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S-A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T-K., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Eriksson, N., Escott-Price, V., Kiadeh, F. H. F., Finucane, H. K., Forstner, A. J., Frank, J., Hansen, T. F., Krogh, J., Thompson, W., Weinsheimer, S. M., Nordentoft, M., Werge, T. & eQTLGen, May 2018, In: Nature Genetics. 50, 5, p. 668-681 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Turcot, V., Lu, Y., Highland, H. M., Schurmann, C., Justice, A. E., Fine, R. S., Bradfield, J. P., Esko, T., Giri, A., Graff, M., Guo, X., Hendricks, A. E., Karaderi, T., Lempradl, A., Locke, A. E., Mahajan, A., Marouli, E., Sivapalaratnam, S., Young, K. L., Alfred, T., Feitosa, M. F., Masca, N. G. D., Manning, A. K., Medina-Gomez, C., Mudgal, P., Ng, M. C. Y., Reiner, A. P., Vedantam, S., Willems, S. M., Winkler, T. W., Abecasis, G., Bang, L. E., Benn, M., Bork-Jensen, J., Friedrich, N., Frikke-Schmidt, R., Hansen, T., Jensen, G. B., Jørgensen, M. E., Jørgensen, T., Kamstrup, P. R., Linneberg, A., Nielsen, S. F., Nordestgaard, B. G., Pers, T. H., Petersen, E. R. B., Thuesen, B. H., Tybjaerg-Hansen, A., Varbo, A., Vestergaard, H. & CHD Exome+ Consortium, May 2018, In: Nature Genetics. 50, 5, p. 765-766 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

    Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P., Flannick, J., Grarup, N., Trubetskoy, V. V., Kravic, J., Kim, Y. J., Rybin, D. V., Yaghootkar, H., Müller-Nurasyid, M., Meidtner, K., Li-Gao, R., Varga, T. V., Marten, J., Li, J., Smith, A. V., An, P., Ligthart, S., Gustafsson, S., Malerba, G., Afzal, S., Bang, L. B., Bork-Jensen, J., Tybjærg-Hansen, A., Jørgensen, M. E., Jørgensen, T., Linneberg, A., Nielsen, S. F., Rode, L., Varbo, A., Rosengren, A. H., Nordestgaard, B. G. & ExomeBP Consortium, Apr 2018, In: Nature Genetics. 50, 4, p. 559-571 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

    Pardiñas, A. F., Holmans, P., Pocklington, A. J., Escott-Price, V., Ripke, S., Carrera, N., Legge, S. E., Bishop, S., Cameron, D., Hamshere, M. L., Han, J., Hubbard, L., Lynham, A., Mantripragada, K., Rees, E., MacCabe, J. H., McCarroll, S. A., Baune, B. T., Breen, G., Byrne, E. M., Dannlowski, U., Eley, T. C., Hayward, C., Martin, N. G., McIntosh, A. M., Plomin, R., Porteous, D. J., Wray, N. R., Caballero, A., Geschwind, D. H., Huckins, L. M., Ruderfer, D. M., Santiago, E., Sklar, P., Stahl, E. A., Won, H., Agerbo, E., Als, T. D., Andreassen, O. A., Bækvad-Hansen, M., Mortensen, P. B., Pedersen, C. B., Børglum, A. D., Bybjerg-Grauholm, J., Djurovic, S., Durmishi, N., Pedersen, M. G., Golimbet, V., Nordentoft, M., Werge, T. & GERAD1 Consortium:, Mar 2018, In: Nature Genetics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes

    Grarup, N., Moltke, I., Andersen, M. K., Dalby, M., Vitting-Seerup, K., Kern, T., Mahendran, Y., Jørsboe, E., Larsen, C. V. L., Dahl-Petersen, I. K., Gilly, A., Suveges, D., Dedoussis, G., Zeggini, E., Pedersen, O., Andersson, R., Bjerregaard, P., Jørgensen, M. E., Albrechtsen, A. & Hansen, T., Jan 2018, In: Nature Genetics. 50, p. 172-174 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

    Demenais, F., Margaritte-Jeannin, P., Barnes, K. C., Cookson, W. O. C., Altmüller, J., Ang, W., Barr, R. G., Beaty, T. H., Becker, A. B., Beilby, J., Bisgaard, H., Bjornsdottir, U. S., Bleecker, E., Bønnelykke, K., Boomsma, D. I., Bouzigon, E., Brightling, C. E., Brossard, M., Brusselle, G. G., Burchard, E., Burkart, K. M., Bush, A., Chan-Yeung, M., Chung, K. F., Couto Alves, A., Curtin, J. A., Custovic, A., Daley, D., de Jongste, J. C., Del-Rio-Navarro, B. E., Donohue, K. M., Duijts, L., Eng, C., Eriksson, J. G., Farrall, M., Fedorova, Y., Feenstra, B., Ferreira, M. A., Freidin, M. B., Gajdos, Z., Gauderman, J., Gehring, U., Geller, F., Genuneit, J., Gharib, S. A., Gilliland, F., Granell, R., Graves, P. E., Waage, J., Wareham, N. J. & Australian Asthma Genetics Consortium (AAGC) collaborators, Jan 2018, In: Nature Genetics. 50, 1, p. 42-53 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Turcot, V., Lu, Y., Highland, H. M., Schurmann, C., Justice, A. E., Fine, R. S., Bradfield, J. P., Esko, T., Giri, A., Graff, M., Guo, X., Hendricks, A. E., Karaderi, T., Lempradl, A., Locke, A. E., Mahajan, A., Marouli, E., Sivapalaratnam, S., Young, K. L., Alfred, T., Feitosa, M. F., Masca, N. G. D., Manning, A. K., Medina-Gomez, C., Mudgal, P., Ng, M. C. Y., Reiner, A. P., Vedantam, S., Willems, S. M., Winkler, T. W., Abecasis, G., Aben, K. K., Alam, D. S., Alharthi, S. E., Bang, L. E., Benn, M., Bork-Jensen, J., Frikke-Schmidt, R., Jensen, G. B., Jørgensen, M. E., Jørgensen, T., Kamstrup, P. R., Linneberg, A., Nielsen, S. F., Nordestgaard, B. G., Pers, T. H., Thuesen, B. H., Tybjaerg-Hansen, A., Varbo, A., Vestergaard, H. & CHD Exome+ Consortium, Jan 2018, In: Nature Genetics. 50, 1, p. 26-41 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Multi-ethnic genome-wide association study for atrial fibrillation

    Chaffin, M. D., Weng, L. C., Aeschbacher, S., Ahlberg, G., Albert, C. M., Almgren, P., Alonso, A., Anderson, C. D., Aragam, K. G., Arking, D. E., Barnard, J., Bartz, T. M., Benjamin, E. J., Bihlmeyer, N. A., Bis, J. C., Bloom, H. L., Boerwinkle, E., Bottinger, E. B., Brody, J. A., Calkins, H., Campbell, A., Cappola, T. P., Carlquist, J., Chasman, D. I., Chen, L. Y., Chen, Y. D. I., Choi, E. K., Choi, S. H., Christophersen, I. E., Chung, M. K., Cole, J. W., Conen, D., Cook, J., Crijns, H. J., Cutler, M. J., Damrauer, S. M., Daniels, B. R., Darbar, D., Delgado, G., Denny, J. C., Dichgans, M., Dörr, M., Dudink, E. A., Dudley, S. C., Esa, N., Olesen, M. S., Refsgaard, L., Svendsen, J. H., Weeke, P. E. & Roselli, Caroline, 2018, In: Nature Genetics. 50, p. 1225-38

    Research output: Contribution to journalLetterpeer-review

  46. 2017
  47. Published

    Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease

    Lu, X., Peloso, G. M., Liu, D. J., Wu, Y., Zhang, H., Zhou, W., Li, J., Tang, C. S-M., Dorajoo, R., Li, H., Long, J., Guo, X., Xu, M., Spracklen, C. N., Chen, Y., Liu, X., Zhang, Y., Khor, C. C., Liu, J., Sun, L., Wang, L., Gao, Y-T., Hu, Y., Yu, K., Wang, Y., Cheung, C. Y. Y., Wang, F., Huang, J., Fan, Q., Cai, Q., Chen, S., Shi, J., Yang, X., Zhao, W., Sheu, W. H-H., Cherny, S. S., He, M., Feranil, A. B., Adair, L. S., Gordon-Larsen, P., Du, S., Varma, R., Chen, Y-D. I., Shu, X-O., Lam, K. S. L., Wong, T. Y., Ganesh, S. K., Mo, Z., Hveem, K., Nielsen, J. B. & GLGC Consortium, Dec 2017, In: Nature Genetics. 49, 12, p. 1722-1730 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

    Milne, R. L., Kuchenbaecker, K. B., Michailidou, K., Beesley, J., Kar, S., Lindström, S., Hui, S., Lemaçon, A., Soucy, P., Dennis, J., Jiang, X., Rostamianfar, A., Finucane, H., Bolla, M. K., McGuffog, L., Wang, Q., Aalfs, C. M., Adams, M., Adlard, J., Agata, S., Ahmed, S., Ahsan, H., Aittomäki, K., Al-Ejeh, F., Allen, J., Ambrosone, C. B., Amos, C. I., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Arndt, V., Arnold, N., Aronson, K. J., Auber, B., Auer, P. L., Ausems, M. G. E. M., Azzollini, J., Bacot, F., Balmaña, J., Barile, M., Barjhoux, L., Barkardottir, R. B., Bojesen, S. E., Ejlertsen, B., Flyger, H., Gerdes, A-M., Hansen, T. V. O., Lænkholm, A-V., Nielsen, S. F., Nordestgaard, B. G. & ABCTB Investigators, Dec 2017, In: Nature Genetics. 49, 12, p. 1767-1778 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

    Zhao, W., Rasheed, A., Tikkanen, E., Lee, J-J., Butterworth, A. S., Howson, J. M. M., Assimes, T. L., Chowdhury, R., Orho-Melander, M., Damrauer, S., Small, A., Asma, S., Imamura, M., Yamauch, T., Chambers, J. C., Chen, P., Sapkota, B. R., Shah, N., Jabeen, S., Surendran, P., Lu, Y., Zhang, W., Imran, A., Abbas, S., Majeed, F., Trindade, K., Qamar, N., Mallick, N. H., Yaqoob, Z., Saghir, T., Rizvi, S. N. H., Memon, A., Rasheed, S. Z., Memon, F-U-R., Mehmood, K., Ahmed, N., Qureshi, I. H., Tanveer-Us-Salam, Iqbal, W., Malik, U., Mehra, N., Kuo, J. Z., Sheu, W. H-H., Guo, X., Nielsen, S. F., Nordestgaard, B. G., Tybjaerg-Hansen, A., Benn, M., Frikke-Schmidt, R., Kamstrup, P. R. & CHD Exome+ Consortium, Oct 2017, In: Nature Genetics. 49, 10, p. 1450-1457 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms

    Howson, J. M. M., Zhao, W., Barnes, D. R., Ho, W-K., Young, R., Paul, D. S., Waite, L. L., Freitag, D. F., Fauman, E. B., Salfati, E. L., Sun, B. B., Eicher, J. D., Johnson, A. D., Sheu, W. H. H., Nielsen, S. F., Lin, W-Y., Surendran, P., Malarstig, A., Wilk, J. B., Tybjærg-Hansen, A., Rasmussen, K. L., Kamstrup, P. R., Deloukas, P., Erdmann, J., Kathiresan, S., Samani, N. J., Schunkert, H., Watkins, H., Do, R., Rader, D. J., Johnson, J. A., Hazen, S. L., Quyyumi, A. A., Spertus, J. A., Pepine, C. J., Franceschini, N., Justice, A., Reiner, A. P., Buyske, S., Hindorff, L. A., Carty, C. L., North, K. E., Kooperberg, C., Boerwinkle, E., Young, K., Graff, M., Peters, U., Absher, D., Hsiung, C. A., Nordestgaard, B. G. & CARDIoGRAMplusC4D, Jul 2017, In: Nature Genetics. 49, 7, p. 1113-1119 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci

    Aung, T., Ozaki, M., Lee, M. C., Schlötzer-Schrehardt, U., Thorleifsson, G., Mizoguchi, T., Igo, R. P., Haripriya, A., Williams, S. E., Astakhov, Y. S., Orr, A. C., Burdon, K. P., Nakano, S., Mori, K., Abu-Amero, K., Hauser, M., Li, Z., Prakadeeswari, G., Bailey, J. N. C., Cherecheanu, A. P., Kang, J. H., Nelson, S., Hayashi, K., Manabe, S-I., Kazama, S., Zarnowski, T., Inoue, K., Irkec, M., Coca-Prados, M., Sugiyama, K., Järvelä, I., Schlottmann, P., Lerner, S. F., Lamari, H., Nilgün, Y., Bikbov, M., Park, K. H., Cha, S. C., Yamashiro, K., Zenteno, J. C., Jonas, J. B., Kumar, R. S., Perera, S. A., Chan, A. S. Y., Kobakhidze, N., George, R., Vijaya, L., Do, T., Edward, D. P., de Juan Marcos, L., Pakravan, M., Moghimi, S., Ideta, R., Bach-Holm, D., Kappelgaard, P., Wirostko, B., Thomas, S., Gaston, D., Bedard, K., Greer, W. L., Yang, Z., Chen, X., Huang, L., Sang, J., Jia, H., Jia, L., Qiao, C., Zhang, H., Liu, X., Zhao, B., Wang, Y-X., Xu, L., Leruez, S., Reynier, P., Chichua, G., Tabagari, S., Uebe, S., Zenkel, M., Berner, D., Mossböck, G., Weisschuh, N., Hoja, U., Welge-Luessen, U-C., Mardin, C., Founti, P., Chatzikyriakidou, A., Pappas, T., Anastasopoulos, E., Lambropoulos, A., Ghosh, A., Shetty, R., Porporato, N., Saravanan, V., Venkatesh, R., Shivkumar, C., Kalpana, N., Sarangapani, S., Kanavi, M. R., Beni, A. N., Yazdani, S., Lashay, A., Naderifar, H., Khatibi, N., Fea, A., Lavia, C., Dallorto, L., Rolle, T., Frezzotti, P., Paoli, D., Salvi, E., Manunta, P., Mori, Y., Miyata, K., Higashide, T., Chihara, E., Ishiko, S., Yoshida, A., Yanagi, M., Kiuchi, Y., Ohashi, T., Sakurai, T., Sugimoto, T., Chuman, H., Aihara, M., Inatani, M., Miyake, M., Gotoh, N., Matsuda, F., Yoshimura, N., Ikeda, Y., Ueno, M., Sotozono, C., Jeoung, J. W., Sagong, M., Park, K. H., Ahn, J., Cruz-Aguilar, M., Ezzouhairi, S. M., Rafei, A., Chong, Y. F., Ng, X. Y., Goh, S. R., Chen, Y., Yong, V. H. K., Khan, M. I., Olawoye, O. O., Ashaye, A. O., Ugbede, I., Onakoya, A., Kizor-Akaraiwe, N., Teekhasaenee, C., Suwan, Y., Supakontanasan, W., Okeke, S., Uche, N. J., Asimadu, I., Ayub, H., Akhtar, F., Kosior-Jarecka, E., Lukasik, U., Lischinsky, I., Castro, V., Grossmann, R. P., Megevand, G. S., Roy, S., Dervan, E., Silke, E., Rao, A., Sahay, P., Fornero, P., Cuello, O., Sivori, D., Zompa, T., Mills, R. A., Souzeau, E., Mitchell, P., Wang, J. J., Hewitt, A. W., Coote, M., Crowston, J. G., Astakhov, S. Y., Akopov, E. L., Emelyanov, A., Vysochinskaya, V., Kazakbaeva, G., Fayzrakhmanov, R., Al-Obeidan, S. A., Owaidhah, O., Aljasim, L. A., Chowbay, B., Foo, J. N., Soh, R. Q., Sim, K. S., Xie, Z., Cheong, A. W. O., Mok, S. Q., Soo, H. M., Chen, X. Y., Peh, S. Q., Heng, K. K., Husain, R., Ho, S-L., Hillmer, A. M., Cheng, C-Y., Escudero-Domínguez, F. A., González-Sarmiento, R., Martinon-Torres, F., Salas, A., Pathanapitoon, K., Hansapinyo, L., Wanichwecharugruang, B., Kitnarong, N., Sakuntabhai, A., Nguyn, H. X., Nguyn, G. T. T., Nguyn, T. V., Zenz, W., Binder, A., Klobassa, D. S., Hibberd, M. L., Davila, S., Herms, S., Nöthen, M. M., Moebus, S., Rautenbach, R. M., Ziskind, A., Carmichael, T. R., Ramsay, M., Álvarez, L., García, M., González-Iglesias, H., Rodríguez-Calvo, P. P., Fernández-Vega Cueto, L., Oguz, Ç., Tamcelik, N., Atalay, E., Batu, B., Aktas, D., Kasım, B., Wilson, M. R., Coleman, A. L., Challa, P., Herndon, L., Kuchtey, R. W., Kuchtey, J., Curtin, K., Chaya, C. J., Crandall, A., Zangwill, L. M., Wong, T. Y., Nakano, M., Kinoshita, S., den Hollander, A. I., Vesti, E., Fingert, J. H., Lee, R. K., Sit, A. J., Shingleton, B. J., Wang, N., Cusi, D., Qamar, R., Kraft, P., Pericak-Vance, M. A., Raychaudhuri, S., Heegaard, S., Kivelä, T., Reis, A., Kruse, F. E., Weinreb, R. N., Pasquale, L. R., Haines, J. L., Thorsteinsdottir, U., Jonasson, F., Allingham, R. R., Milea, D., Ritch, R., Kubota, T., Tashiro, K., Vithana, E. N., Micheal, S., Topouzis, F., Craig, J. E., Dubina, M., Sundaresan, P., Stefansson, K., Wiggs, J. L., Pasutto, F. & Khor, C. C., Jul 2017, In: Nature Genetics. 49, 7, p. 993-1004 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

    McKay, J. D., Hung, R. J., Han, Y., Zong, X., Carreras-Torres, R., Christiani, D. C., Caporaso, N. E., Johansson, M., Xiao, X., Li, Y., Byun, J., Dunning, A., Pooley, K. A., Qian, D. C., Ji, X., Liu, G., Timofeeva, M. N., Bojesen, S. E., Wu, X., Le Marchand, L., Albanes, D., Bickeböller, H., Aldrich, M. C., Bush, W. S., Tardon, A., Rennert, G., Teare, M. D., Field, J. K., Kiemeney, L. A., Lazarus, P., Haugen, A., Lam, S., Schabath, M. B., Andrew, A. S., Shen, H., Hong, Y-C., Yuan, J-M., Bertazzi, P. A., Pesatori, A. C., Ye, Y., Diao, N., Su, L., Zhang, R., Brhane, Y., Leighl, N., Johansen, J. S., Mellemgaard, A., Saliba, W., Haiman, C. A., Wilkens, L. R. & SpiroMeta Consortium, Jul 2017, In: Nature Genetics. 49, 7, p. 1126-1132 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

    Weiner, D. J., Wigdor, E. M., Ripke, S., Walters, R. K., Kosmicki, J. A., Grove, J., Samocha, K. E., Goldstein, J. I., Okbay, A., Bybjerg-Grauholm, J., Werge, T., Hougaard, D. M., Taylor, J., Skuse, D., Devlin, B., Anney, R., Sanders, S. J., Bishop, S., Mortensen, P. B., Børglum, A. D., Smith, G. D., Daly, M. J., Robinson, E. B., iPSYCH-Broad Autism Group & Hansen, T. F., Jul 2017, In: Nature Genetics. 49, 7, p. 978-985 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor

    Wang, Z., McGlynn, K. A., Rajpert-De Meyts, E., Bishop, D. T., Chung, C. C., Dalgaard, M. D., Greene, M. H., Gupta, R., Grotmol, T., Haugen, T. B., Karlsson, R., Litchfield, K., Mitra, N., Nielsen, K., Pyle, L. C., Schwartz, S. M., Thorsson, V., Vardhanabhuti, S., Wiklund, F., Turnbull, C., Chanock, S. J., Kanetsky, P. A., Nathanson, K. L. & Testicular Cancer Consortium, 12 Jun 2017, In: Nature Genetics. 49, 7, p. 1141–1147 doi:10.1038/ng.3879.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci

    Stender, S., Kozlitina, J., Nordestgaard, B. G., Tybjærg-Hansen, A., Hobbs, H. H. & Cohen, J. C., Jun 2017, In: Nature Genetics. 49, 6, p. 842-847 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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