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The Capital Region of Denmark - a part of Copenhagen University Hospital

Antimicrobial Agents and Chemotherapy, 0066-4804

Journal

  1. 2020
  2. E-pub ahead of print
  3. Published
  4. Published
  5. Published

    Biofilms of Mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation

    Kolpen, M., Jensen, P. Ø., Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, B. G., Johansen, U. R., Bjarnsholt, T. & Høiby, N., 27 Jan 2020, In : Antimicrobial Agents and Chemotherapy. 64, 2, p. e01212-19 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2019
  7. Published

    Lack of the Major Multifunctional Catalase KatA in Pseudomonas aeruginosa Accelerates Evolution of Antibiotic Resistance in Ciprofloxacin-Treated Biofilms

    Ahmed, M. N., Porse, A., Abdelsamad, A., Sommer, M., Høiby, N. & Ciofu, O., Oct 2019, In : Antimicrobial Agents and Chemotherapy. 63, 10, p. e00766-19

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    EUCAST Reference Testing of Rezafungin Susceptibility and Impact of Choice of Plastic Plates

    Arendrup, M. C., Jørgensen, K. M., Hare, R. K., Cuenca-Estrella, M. & Zaragoza, O., Sep 2019, In : Antimicrobial Agents and Chemotherapy. 63, 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    EUCAST Susceptibility Testing of Isavuconazole: MIC Data for Contemporary Clinical Mold and Yeast Isolates

    Jørgensen, K. M., Astvad, K. M. T., Hare, R. K. & Arendrup, M. C., Jun 2019, In : Antimicrobial Agents and Chemotherapy. 63, 6, p. 3708–3718

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published
  11. Published

    Emerging Terbinafine Resistance in Trichophyton: Clinical Characteristics, Squalene Epoxidase Gene Mutations, and a Reliable EUCAST Method for Detection

    Saunte, D. M. L., Hare, R. K., Jørgensen, K. M., Jørgensen, R., Deleuran, M., Zachariae, C. O., Thomsen, S. F., Bjørnskov-Halkier, L., Kofoed, K. & Arendrup, M. C., 1 Jan 2019, In : Antimicrobial Agents and Chemotherapy. 63, 10, e01126-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    In-vivo gentamicin susceptibility test for prevention of bacterial biofilms in bone tissue and on implants

    Jensen, L. K., Bjarnsholt, T., Kragh, K. N., Aalbæk, B., Henriksen, N. L., Blirup, S. A., Pankoke, K., Petersen, A. & Jensen, H. E., 2019, In : Antimicrobial Agents and Chemotherapy. 63, 2, p. e01889-18

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2018
  14. Published

    Implications of the EUCAST Trailing Phenomenon in Candida tropicalis for the In Vivo Susceptibility in Invertebrate and Murine Models

    Astvad, K. M. T., Sanglard, D., Delarze, E., Hare, R. K. & Arendrup, M. C., Dec 2018, In : Antimicrobial Agents and Chemotherapy. 62, 12, p. e01624-18

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    APX001A In Vitro Activity against Contemporary Blood Isolates and Candida auris Determined by the EUCAST Reference Method

    Arendrup, M. C., Chowdhary, A., Astvad, K. M. T. & Jørgensen, K. M., Oct 2018, In : Antimicrobial Agents and Chemotherapy. 62, 10, p. e01225-18

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Population Pharmacokinetics of the Antimalarial Amodiaquine: a Pooled Analysis To Optimize Dosing

    Kurtzhals, J. A. L. & WWARN Amodiaquine PK Study Group , Oct 2018, In : Antimicrobial Agents and Chemotherapy. 62, 10, p. e02193-17

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Erratum for Hertz et al., "Antibiotic Selection of Escherichia coli Sequence Type 131 in a Mouse Intestinal Colonization Model"

    Hertz, F. B., Løbner-Olesen, A. & Frimodt-Møller, N., Sep 2018, In : Antimicrobial Agents and Chemotherapy. 58, 10, p. 6139-6114

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    EUCAST Determination of Olorofim (F901318) Susceptibility of Mold Species, Method Validation, and MICs

    Jørgensen, K. M., Astvad, K. M. T., Hare, R. K. & Arendrup, M. C., Aug 2018, In : Antimicrobial Agents and Chemotherapy. 62, 8, p. e00487-18

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Evolution of Antibiotic Resistance in Biofilm and Planktonic Pseudomonas aeruginosa Populations Exposed to Subinhibitory Levels of Ciprofloxacin

    Ahmed, M. N., Porse, A., Sommer, M. O. A., Høiby, N. & Ciofu, O., Aug 2018, In : Antimicrobial Agents and Chemotherapy. 62, 8, p. e00320-18

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Pharmacokinetics and Pharmacodynamics of Fosfomycin and Its Activity against Extended-Spectrum-β-Lactamase-, Plasmid-Mediated AmpC-, and Carbapenemase-Producing Escherichia coli in a Murine Urinary Tract Infection Model

    Zykov, I. N., Samuelsen, Ø., Jakobsen, L., Småbrekke, L., Andersson, D. I., Sundsfjord, A. & Frimodt-Møller, N., Jun 2018, In : Antimicrobial Agents and Chemotherapy. 62, 6, p. e02560-17

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Population Pharmacokinetics of Meropenem in Plasma and Subcutis from Patients on Extracorporeal Membrane Oxygenation Treatment

    Hanberg, P., Öbrink-Hansen, K., Thorsted, A., Bue, M., Tøttrup, M., Friberg, L. E., Hardlei, T. F., Søballe, K. & Gjedsted, J., May 2018, In : Antimicrobial Agents and Chemotherapy. 62, 5, p. e02390-17

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Dissemination and Characteristics of a Novel Plasmid-Encoded Carbapenem-Hydrolyzing Class D β-Lactamase, OXA-436 from Four Patients Involving Six Different Hospitals in Denmark

    Samuelsen, Ø., Hansen, F., Aasnæs, B., Hasman, H., Lund, B. A., Leiros, H-K. S., Lilje, B., Janice, J., Jakobsen, L., Littauer, P., Søes, L. M., Holzknecht, B. J., Andersen, L. P., Stegger, M., Andersen, P. S. & Hammerum, A. M., 2018, In : Antimicrobial Agents and Chemotherapy. 62, 1, p. e01260-17

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2017
  24. Published

    Hyperbaric Oxygen Sensitizes Anoxic Pseudomonas aeruginosa Biofilm to Ciprofloxacin

    Kolpen, M., Lerche, C. J., Kragh, K. N., Sams, T., Koren, K., Jensen, A. S., Line, L., Bjarnsholt, T., Ciofu, O., Moser, C., Kühl, M., Høiby, N. & Jensen, P. Ø., Nov 2017, In : Antimicrobial Agents and Chemotherapy. 61, 11, p. e01024-17

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Fluconazole Pharmacokinetics in Galleria mellonella Larvae and Performance Evaluation of a Bioassay Compared to Liquid Chromatography-Tandem Mass Spectrometry for Hemolymph Specimens

    Astvad, K. M. T., Meletiadis, J., Whalley, S. & Arendrup, M. C., Oct 2017, In : Antimicrobial Agents and Chemotherapy. 61, 10, p. e00895-17

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published
  27. Published

    Evolutionary origin of the staphylococcal cassette chromosome mec (SCCmec)

    Rolo, J., Worning, P., Nielsen, J. B., Bowden, R., Bouchami, O., Damborg, P. P., Guardabassi, L., Perreten, V., Tomasz, A., Westh, H., de Lencastre, H. & Miragaia, M., 1 Jun 2017, In : Antimicrobial Agents and Chemotherapy. 61, 6, p. 1-16 e02302-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Comparison of EUCAST and CLSI Reference Microdilution MICs of Eight Antifungal Compounds for Candida auris and Associated Tentative Epidemiological Cutoff Values

    Arendrup, M. C., Prakash, A., Meletiadis, J., Sharma, C. & Chowdhary, A., Jun 2017, In : Antimicrobial Agents and Chemotherapy. 61, 6, p. e00485-17

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Evaluation of MIC Strip Isavuconazole Test for Susceptibility Testing of Wild-Type and Non-Wild-Type Aspergillus fumigatus Isolates

    Arendrup, M. C., Verweij, P. & Nielsen, H. V., Jan 2017, In : Antimicrobial Agents and Chemotherapy. 61, 1, p. e01659-16

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Multicenter Study of Method-Dependent Epidemiological Cutoff Values for Detection of Resistance in Candida spp. and Aspergillus spp. to Amphotericin B and Echinocandins for the Etest Agar Diffusion Method

    Espinel-Ingroff, A., Arendrup, M., Cantón, E., Cordoba, S., Dannaoui, E., García-Rodríguez, J., Gonzalez, G. M., Govender, N. P., Martin-Mazuelos, E., Lackner, M., Lass-Flörl, C., Linares Sicilia, M. J., Rodriguez-Iglesias, M. A., Pelaez, T., Shields, R. K., Garcia-Effron, G., Guinea, J., Sanguinetti, M. & Turnidge, J., Jan 2017, In : Antimicrobial Agents and Chemotherapy. 61, 1, p. e01792-16

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2016
  32. Published
  33. Published

    OligoG CF-5/20 Disruption of Mucoid Pseudomonas aeruginosa Biofilm in a Murine Lung Infection Model

    Hengzhuang, W., Song, Z., Ciofu, O., Onsøyen, E., Rye, P. D. & Høiby, N., May 2016, In : Antimicrobial Agents and Chemotherapy. 60, 5, p. 2620-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Post treatment antifungal resistance among colonizing Candida isolates in candidemia patients: results from a systematic multicenter study

    Jensen, R. H., Johansen, H. K., Søes, L. M., Lemming, L. E., Rosenvinge, F. S., Nielsen, L., Olesen, B., Kristensen, L., Dzajic, E., Astvad, K. M. T. & Arendrup, M. C., 2016, In : Antimicrobial Agents and Chemotherapy. 60, 3, p. 1500-08

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 2015
  36. Published
  37. Population pharmacokinetics of piperacillin in the early phase of septic shock: does standard dosing result in therapeutic plasma concentrations?

    Öbrink-Hansen, K., Juul, R. V., Storgaard, M., Thomsen, M. K., Hardlei, T. F., Brock, B., Kreilgaard, M. & Gjedsted, J., Nov 2015, In : Antimicrobial Agents and Chemotherapy. 59, 11, p. 7018-26 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The Soil Microbiota Harbors a Diversity of Carbapenem-Hydrolyzing ß-Lactamases of Potential Clinical Relevance

    Gudeta, D. D., Bortolaia, V., Amos, G., Wellington, E. M. H., Brandt, K. K., Poirel, L., Nielsen, J. B., Westh, H. & Guardabassi, L., 19 Oct 2015, In : Antimicrobial Agents and Chemotherapy. p. 151-160 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Prevalence of Plasmodium falciparum resistance markers to sulfadoxine-pyrimethamine among pregnant women receiving intermittent preventive treatment for malaria in Uganda

    Mbonye, A. K., Birungi, J., Yanow, S. K., Shokoples, S., Malamba, S., Alifrangis, M. & Magnussen, P., Sep 2015, In : Antimicrobial Agents and Chemotherapy. 59, 9, p. 5475-82 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Effects of a Mutation in the gyrA Gene on the Virulence of Uropathogenic Escherichia coli

    Sánchez-Céspedes, J., Sáez-López, E., Frimodt-Møller, N., Vila, J. & Soto, S. M., Aug 2015, In : Antimicrobial Agents and Chemotherapy. 59, 8, p. 4662-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Results of a multinational study suggest the need for rapid diagnosis and early antiviral treatment at the onset of herpetic meningoencephalitis

    Erdem, H., Cag, Y., Ozturk-Engin, D., Defres, S., Kaya, S., Larsen, L., Poljak, M., Barsic, B., Argemi, X., Sørensen, S. M., Bohr, A. L., Tattevin, P., Gunst, J. D., Baštáková, L., Jereb, M., Johansen, I. S., Karabay, O., Pekok, A. U., Sipahi, O. R., Chehri, M., Beraud, G., Shehata, G., Del Vecchio, R. F., Maresca, M., Karsen, H., Sengoz, G., Sunbul, M., Yilmaz, G., Yilmaz, H., Sharif-Yakan, A., Kanj, S. S., Parlak, E., Pehlivanoglu, F., Korkmaz, F., Komur, S., Kose, S., Ulug, M., Bolukcu, S., Coskuner, S. A., Ince, N., Akkoyunlu, Y., Halac, G., Sahin-Horasan, E., Tireli, H., Kilicoglu, G., Al-Mahdawi, A., Nemli, S. A., Inan, A., Senbayrak, S., Stahl, J. P. & Vahaboglu, H., Jun 2015, In : Antimicrobial Agents and Chemotherapy. 59, 6, p. 3084-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The New Macrolide-Lincosamide-Streptogramin B Resistance Gene erm(45) Is Located within a Genomic Island in Staphylococcus fleurettii

    Wipf, J. R. K., Schwendener, S., Nielsen, J. B., Westh, H. & Perreten, V., Jun 2015, In : Antimicrobial Agents and Chemotherapy. 59, 6, p. 3578-81 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Moxifloxacin pharmacokinetic profile and efficacy evaluation in empiric treatment of community-acquired pneumonia

    Öbrink-Hansen, K., Hardlei, T. F., Brock, B., Jensen-Fangel, S., Kragh Thomsen, M., Petersen, E. & Kreilgaard, M., Apr 2015, In : Antimicrobial Agents and Chemotherapy. 59, 4, p. 2398-404 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    An Amphipathic Undecapeptide with All d-Amino Acids Shows Promising Activity against Colistin-Resistant Strains of Acinetobacter baumannii and a Dual Mode of Action

    Oddo, A., Thomsen, T. T., Kjelstrup, S., Gorey, C., Franzyk, H., Frimodt-Møller, N., Løbner-Olesen, A. & Hansen, P. R., 2015, In : Antimicrobial Agents and Chemotherapy. 60, 1, p. 592-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2014
  46. Published

    Temporal Trends in Antimicrobial Resistance and Virulence-Associated Traits within the Escherichia coli Sequence Type 131 Clonal Group and Its H30 and H30-Rx Subclones, 1968 to 2012

    Olesen, B., Frimodt-Møller, J., Leihof, R. F., Struve, C., Johnston, B., Hansen, D. S., Scheutz, F., Krogfelt, K. A., Kuskowski, M. A., Clabots, C. & Johnson, J. R., Nov 2014, In : Antimicrobial Agents and Chemotherapy. 58, 11, p. 6886-95 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Antibiotic selection of Escherichia coli sequence type 131 in a mouse intestinal colonization model

    Boetius Hertz, F., Løbner-Olesen, A. & Frimodt-Møller, N., Oct 2014, In : Antimicrobial Agents and Chemotherapy. 58, 10, p. 6139-44 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Nutritional supplementation increases rifampin exposure among tuberculosis patients coinfected with HIV

    Jeremiah, K., Denti, P., Chigutsa, E., Faurholt-Jepsen, D., PrayGod, G., Range, N., Castel, S., Wiesner, L., Hagen, C. M., Christiansen, M., Changalucha, J., McIlleron, H., Friis, H. & Andersen, A. B., Jun 2014, In : Antimicrobial Agents and Chemotherapy. 58, 6, p. 3468-74 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Pharmacokinetics of cefuroxime in porcine cortical and cancellous bone determined by microdialysis

    Tøttrup, M., Hardlei, T. F., Bendtsen, M., Bue, M., Brock, B., Fuursted, K., Søballe, K. & Birke-Sørensen, H., Jun 2014, In : Antimicrobial Agents and Chemotherapy. 58, 6, p. 3200-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    A novel method for identification of the optimal antimicrobial peptide in a combination matrix, using anoplin as an example

    Munk, J., Ritz, C., Fliedner, F. P., Frimodt-Møller, N. & Hansen, P. R., 1 Feb 2014, In : Antimicrobial Agents and Chemotherapy. 58, 2, p. 1063-1070 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2013
  52. Published
  53. Published

    Sublethal ciprofloxacin treatment leads to rapid development of high-level ciprofloxacin resistance during long-term experimental evolution of Pseudomonas aeruginosa

    Jørgensen, K. M., Wassermann, T., Jensen, P. Ø., Wang, H., Molin, S., Høiby, N. & Ciofu, O., Sep 2013, In : Antimicrobial Agents and Chemotherapy. 57, 9, p. 4215-21 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms

    Chiang, W-C., Nilsson, M., Jensen, P. Ø., Høiby, N., Nielsen, T. E., Givskov, M. C. & Tolker-Nielsen, T., May 2013, In : Antimicrobial Agents and Chemotherapy. 57, 5, p. 2352-61 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Polymyxin resistance of Pseudomonas aeruginosa phoQ mutants is dependent on additional two-component regulatory systems

    Gutu, A. D., Sgambati, N., Strasbourger, P., Brannon, M. K., Jacobs, M. A., Haugen, E., Kaul, R. K., Johansen, H. K., Høiby, N. & Moskowitz, S. M., May 2013, In : Antimicrobial Agents and Chemotherapy. 57, 5, p. 2204-15 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published
  57. Published
  58. Published

    High β-Lactamase Levels Change the Pharmacodynamics of β-Lactam Antibiotics in Pseudomonas aeruginosa Biofilms

    Hengzhuang, W., Ciofu, O., Yang, L., Wu, H., Song, Z., Oliver, A. & Høiby, N., 2013, In : Antimicrobial Agents and Chemotherapy. 57, 1, p. 196-204 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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