Workup and treatment of patients with obstructive cholestasis

Frederik Hertervig, Peter Vilmann, Bojan Kovacevic

Abstract

The causes of cholestasis range from intrinsic hepatocellular disease to extrahepatic mechanical obstruction of the bile tree. Gallstones are the most common cause of obstructive cholestasis, but it is not seldomly associated with malignant disease. A systematic approach to diagnosing cholestatic liver disease, including thorough patient history, clinical examination, lab-panels and proper use of imaging and treatment alternatives, starting from least invasive and most cost-effective, ensures efficient patient outcomes and minimises the risk of complications as summarised in this review.

OriginalsprogEngelsk
TidsskriftUgeskrift for Laeger
Vol/bind183
Udgave nummer10
ISSN0041-5782
StatusUdgivet - 8 mar. 2021

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