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Whole Genome Sequencing of Danish Staphylococcus argenteus Reveals a Genetically Diverse Collection with Clear Separation from Staphylococcus aureus

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  1. Staphylococcus saprophyticus From Clinical and Environmental Origins Have Distinct Biofilm Composition

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Rapid Open-Source SNP-Based Clustering Offers an Alternative to Core Genome MLST for Outbreak Tracing in a Hospital Setting

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Azole-Resistant Aspergillus fumigatus Among Danish Cystic Fibrosis Patients: Increasing Prevalence and Dominance of TR34/L98H

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Staphylococcus argenteus (S. argenteus) is a newly identified Staphylococcus species that has been misidentified as Staphylococcus aureus (S. aureus) and is clinically relevant. We identified 25 S. argenteus genomes in our collection of whole genome sequenced S. aureus. These genomes were compared to publicly available genomes and a phylogeny revealed seven clusters corresponding to seven clonal complexes. The genome of S. argenteus was found to be different from the genome of S. aureus and a core genome analysis showed that ~33% of the total gene pool was shared between the two species, at 90% homology level. An assessment of mobile elements shows flow of SCCmec cassettes, plasmids, phages, and pathogenicity islands, between S. argenteus and S. aureus. This dataset emphasizes that S. argenteus and S. aureus are two separate species that share genetic material.

OriginalsprogEngelsk
TidsskriftFrontiers in Microbiology
Vol/bind8
Sider (fra-til)1512
ISSN1664-302X
DOI
StatusUdgivet - 2017

ID: 51953494