Which patients benefit most from adjuvant aromatase inhibitors? Results using a composite measure of prognostic risk in the BIG 1-98 randomized trial

G Viale, M M Regan, P Dell'Orto, M G Mastropasqua, E Maiorano, B B Rasmussen, G MacGrogan, J F Forbes, R J Paridaens, M Colleoni, I Láng, B Thürlimann, H Mouridsen, L Mauriac, R D Gelber, K N Price, A Goldhirsch, B A Gusterson, A S Coates, BIG 1-98 Collaborative and International Breast Cancer Study Groups

93 Citationer (Scopus)

Abstract

On average, aromatase inhibitors are better than tamoxifen when used as initial or sequential therapy for postmenopausal women with endocrine-responsive early breast cancer. Because there may be contraindications to their use based on side-effects or cost, we investigated subgroups in which aromatase inhibitors may be more or less important.
OriginalsprogEngelsk
TidsskriftAnnals of Oncology
Vol/bind22
Udgave nummer10
Sider (fra-til)2201-7
Antal sider7
ISSN0923-7534
DOI
StatusUdgivet - 2011

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