When and how should multiple imputation be used for handling missing data in randomised clinical trials - a practical guide with flowcharts

Keyphrases

• Missing Data 100%
• Randomized Clinical Trial 100%
• Multiple Imputation 100%
• Practical Guide 100%
• Handling Missing Data 100%
• PubMed 11%
• Statistical Analysis 11%
• Sensitivity Analysis 11%
• Potential Bias 11%
• Trial Data 11%
• Analytical Method 11%
• Simulation Study 11%
• Optimal Way 11%
• Analytical Approach 11%
• Bias Potential 11%
• Missingness 11%
• Careful Planning 11%
• Full Information Maximum Likelihood 11%
• Best-worst 11%

Mathematics

• Handling Missing Data 100%
• Multiple Imputation 100%
• Minimizes 33%
• Simulation Study 33%
• Maximum Likelihood 33%
• Statistical Analysis 33%
• Missing Value 33%
• Missingness 33%