Well-Being and Self-Disorders in Schizotypal Disorder and Asperger Syndrome/Autism Spectrum Disorder

Maria Nilsson, Peter Handest, Jessica Carlsson, Lena Nylander, Lennart Pedersen, Erik Lykke Mortensen, Sidse Arnfred


We explored subjective well-being in two groups of young adult participants
diagnosed with either schizotypal disorder (Sd) (n = 29) or Asperger syndrome/autism spectrum disorder (As/ASD) (n = 22). Well-being was impaired
in both groups and was lower in the Sd group than in the As/ASD group.
Furthermore, there was a negative correlation between well-being and the presence of self-disorders. The negative effect of self-disorders on well-beingwas still significant when adjusted for diagnosis, age and gender, and level of function. The present findings point toward clinically important disorder-specific differences in the nature of impaired well-being between the Sd group and the As/ASD group, as there seems to be a self-disorder–driven additional contribution to impaired subjectivewell-being within the schizophrenia spectrum. These findings further nuance the understanding of fundamental and clinically important qualitative differences between the schizophrenia spectrum and the autism spectrum.
TidsskriftJournal of Nervous and Mental Disease
Udgave nummer5
Sider (fra-til)418-423
Antal sider6
StatusUdgivet - maj 2020


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