Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Visual binding abilities in the initial and advanced stages of schizophrenia.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Trajectory of cognitive functions in bipolar disorder: for better or worse?

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Incidence of suicidal behaviour and violent crime following antidepressant medication: a Danish cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Response to comment on Osler et al: misinterpretation of pre- and post differences invalidate the authors' conclusion

    Publikation: Bidrag til tidsskriftKommentar/debatForskningpeer review

  4. Societal costs of Borderline Personality Disorders: a matched-controlled nationwide study of patients and spouses

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Meta-analysis of antidepressant effects of anti-inflammatory drugs-reply

    Publikation: Bidrag til tidsskriftKommentar/debatForskningpeer review

  1. Schizophrenia-spectrum psychopathology in obsessive-compulsive disorder: an empirical study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. 'The schizophrenic basic mood (self-disorder)', by Hans W Gruhle (1929)

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Altered self-recognition in patients with schizophrenia

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. The neurophenomenology of early psychosis: An integrative empirical study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Double bookkeeping and schizophrenia spectrum: divided unified phenomoenal consciousness

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

OBJECTIVE: The study tests the hypothesis that intramodal visual binding is disturbed in schizophrenia and should be detectable in all illness stages as a stable trait marker.

METHOD: Three groups of patients (rehospitalized chronic schizophrenic, first admitted schizophrenic and schizotypal patients believed to be suffering from a pre-schizophrenic prodrome) and a group of normal control subjects were tested on three tasks targeting visual 'binding' abilities (Muller-Lyer's illusion and two figure detection tasks) in addition to control parameters such as reaction time, visual selective attention, Raven's test and two conventional cortical tasks of spatial working memory (SWM) and a global local test.

RESULTS: Chronic patients had a decreased performance on the binding tests. Unexpectedly, the prodromal group exhibited an enhanced Gestalt extraction on these tests compared both to schizophrenic patients and to healthy subjects. Furthermore, chronic schizophrenia was associated with a poor performance on cortical tests of SWM, global local and on Raven. This association appears to be mediated by or linked to the chronicity of the illness.

CONCLUSION: The study confirms a variety of neurocognitive deficits in schizophrenia which, however, in this sample seem to be linked to chronicity of illness. However, certain aspects of visual processing concerned with Gestalt extraction deserve attention as potential vulnerability- or prodrome- indicators. The initial hypothesis of the study is rejected.

Bidragets oversatte titelVisual binding abilities in the initial and advanced stages of schizophrenia.
OriginalsprogEngelsk
TidsskriftActa Psychiatrica Scandinavica
Vol/bind103
Udgave nummer3
Sider (fra-til)171-80
Antal sider10
ISSN0001-690X
StatusUdgivet - mar. 2001

ID: 32525326