Viral hepatitis: Cell-culture-derived HCV--a promising vaccine antigen

Judith M Gottwein; Jens Bukh

doi:10.1038/nrgastro.2013.136

Viral hepatitis: Cell-culture-derived HCV--a promising vaccine antigen

14 Citationer (Scopus)

Abstract

With millions of humans infected yearly with HCV, leading to cirrhosis and cancer, a vaccine is urgently needed. Cultured virus particles constitute the antigen in most antiviral vaccines. A study in mice demonstrated induction of neutralizing antibodies by immunization with cell-culture-derived HCV, providing new possibilities for vaccine development.

Originalsprog	Engelsk
Tidsskrift	Nature reviews. Gastroenterology & hepatology
Vol/bind	10
Udgave nummer	9
Sider (fra-til)	508-9
Antal sider	2
ISSN	1759-5045
DOI	https://doi.org/10.1038/nrgastro.2013.136
Status	Udgivet - sep. 2013

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10.1038/nrgastro.2013.136

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abstract = "With millions of humans infected yearly with HCV, leading to cirrhosis and cancer, a vaccine is urgently needed. Cultured virus particles constitute the antigen in most antiviral vaccines. A study in mice demonstrated induction of neutralizing antibodies by immunization with cell-culture-derived HCV, providing new possibilities for vaccine development.",

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Viral hepatitis: Cell-culture-derived HCV--a promising vaccine antigen

Abstract

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