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Vertiginous Episodes in Menière Disease following Transmyringeal Ventilation Tube Insertion: A Systematic Review on the Current State of Evidence

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Grønlund, Casper ; Devantier, Louise ; Callesen, Henriette Edemann ; Hougaard, Dan Dupont ; Händel, Mina Nicole ; Schmidt, Jesper Hvass ; Guldfred, Frank Liviu-Adelin ; Djurhuus, Bjarki Ditlev. / Vertiginous Episodes in Menière Disease following Transmyringeal Ventilation Tube Insertion : A Systematic Review on the Current State of Evidence. I: International Archives of Otorhinolaryngology. 2021 ; Bind 25, Nr. 3. s. e463-e470.

Bibtex

@article{d8df7baf3d2a4cca83477bb7e360fbc6,
title = "Vertiginous Episodes in Meni{\`e}re Disease following Transmyringeal Ventilation Tube Insertion: A Systematic Review on the Current State of Evidence",
abstract = "Introduction  Meni{\`e}re disease (MD) is a disorder characterized by episodes of vertigo, sensorineural hearing loss, tinnitus and aural fullness. Objectives  To assess the effect of ventilation tube insertion (VTI) on vertiginous episodes in patients (≥ 18 years old) with MD. Data Synthesis  A systematic literature search on randomized clinical trials (RCTs), nonrandomized trials and other systematic reviews was performed. The Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) approach was used to assess the overall certainty of evidence. Two RCTs and four nonrandomized studies were identified. Data extraction was only possible for one RCT. Results showed that the number of patients with no vertigo attacks significantly increased following active treatment (relative risk 1.52; [95% confidence interval: 1.19-1.94]). The quality of evidence was rated as low. None of the nonrandomized trials included a proper control group, which hindered data extraction and quality assessment. Conclusion  There are currently no RCTs that specifically assess the efficacy of VTI in patients with MD. Current limited data suggest a considerable positive effect on the number of vertiginous episodes in patients with MD. However, due to poor evidence, a fluctuating course and a substantial placebo-effect associated with MD-treatment, no solid conclusion(s) regarding the efficacy of VTI can be made. There is a need for high-quality RCTs.",
keywords = "Dizziness, Hearing, Meniere disease, Ventilation tube insertion, Vertigo",
author = "Casper Gr{\o}nlund and Louise Devantier and Callesen, {Henriette Edemann} and Hougaard, {Dan Dupont} and H{\"a}ndel, {Mina Nicole} and Schmidt, {Jesper Hvass} and Guldfred, {Frank Liviu-Adelin} and Djurhuus, {Bjarki Ditlev}",
note = "Funda{\c c}{\~a}o Otorrinolaringologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ).",
year = "2021",
month = jul,
doi = "10.1055/s-0040-1714131",
language = "English",
volume = "25",
pages = "e463--e470",
journal = "International Archives of Otorhinolaryngology",
issn = "1809-9777",
publisher = "Thieme Medical Publishers Inc.",
number = "3",

}

RIS

TY - JOUR

T1 - Vertiginous Episodes in Menière Disease following Transmyringeal Ventilation Tube Insertion

T2 - A Systematic Review on the Current State of Evidence

AU - Grønlund, Casper

AU - Devantier, Louise

AU - Callesen, Henriette Edemann

AU - Hougaard, Dan Dupont

AU - Händel, Mina Nicole

AU - Schmidt, Jesper Hvass

AU - Guldfred, Frank Liviu-Adelin

AU - Djurhuus, Bjarki Ditlev

N1 - Fundação Otorrinolaringologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ).

PY - 2021/7

Y1 - 2021/7

N2 - Introduction  Menière disease (MD) is a disorder characterized by episodes of vertigo, sensorineural hearing loss, tinnitus and aural fullness. Objectives  To assess the effect of ventilation tube insertion (VTI) on vertiginous episodes in patients (≥ 18 years old) with MD. Data Synthesis  A systematic literature search on randomized clinical trials (RCTs), nonrandomized trials and other systematic reviews was performed. The Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) approach was used to assess the overall certainty of evidence. Two RCTs and four nonrandomized studies were identified. Data extraction was only possible for one RCT. Results showed that the number of patients with no vertigo attacks significantly increased following active treatment (relative risk 1.52; [95% confidence interval: 1.19-1.94]). The quality of evidence was rated as low. None of the nonrandomized trials included a proper control group, which hindered data extraction and quality assessment. Conclusion  There are currently no RCTs that specifically assess the efficacy of VTI in patients with MD. Current limited data suggest a considerable positive effect on the number of vertiginous episodes in patients with MD. However, due to poor evidence, a fluctuating course and a substantial placebo-effect associated with MD-treatment, no solid conclusion(s) regarding the efficacy of VTI can be made. There is a need for high-quality RCTs.

AB - Introduction  Menière disease (MD) is a disorder characterized by episodes of vertigo, sensorineural hearing loss, tinnitus and aural fullness. Objectives  To assess the effect of ventilation tube insertion (VTI) on vertiginous episodes in patients (≥ 18 years old) with MD. Data Synthesis  A systematic literature search on randomized clinical trials (RCTs), nonrandomized trials and other systematic reviews was performed. The Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) approach was used to assess the overall certainty of evidence. Two RCTs and four nonrandomized studies were identified. Data extraction was only possible for one RCT. Results showed that the number of patients with no vertigo attacks significantly increased following active treatment (relative risk 1.52; [95% confidence interval: 1.19-1.94]). The quality of evidence was rated as low. None of the nonrandomized trials included a proper control group, which hindered data extraction and quality assessment. Conclusion  There are currently no RCTs that specifically assess the efficacy of VTI in patients with MD. Current limited data suggest a considerable positive effect on the number of vertiginous episodes in patients with MD. However, due to poor evidence, a fluctuating course and a substantial placebo-effect associated with MD-treatment, no solid conclusion(s) regarding the efficacy of VTI can be made. There is a need for high-quality RCTs.

KW - Dizziness

KW - Hearing

KW - Meniere disease

KW - Ventilation tube insertion

KW - Vertigo

UR - http://www.scopus.com/inward/record.url?scp=85093645477&partnerID=8YFLogxK

U2 - 10.1055/s-0040-1714131

DO - 10.1055/s-0040-1714131

M3 - Review

C2 - 34377186

VL - 25

SP - e463-e470

JO - International Archives of Otorhinolaryngology

JF - International Archives of Otorhinolaryngology

SN - 1809-9777

IS - 3

M1 - 190098SR

ER -

ID: 67551919