Ventrikelcancer er den hyppigste Epstein-Barr-virus-associerede cancerform

Trine Boysen, Jeppe Friborg

Abstract

Epstein-Barr virus (EBV) is associated with 8% of gastric carcinomas (GC) worldwide, being the most frequent EBV-associated malignancy with 80,000 new cases per year. The association is based on the presence of clonal EBV products in gastric tumour cells, and elevated EBV antibodies in pre-diagnostic sera. EBV-associated GC are twice as common in males and often associated to cancer in the cardia-region. Gastric surgery increases the risk significantly. Until now, no clear interaction between Helicobacter pylori, the single most important risk factor for GC, and EBV has been established.

Bidragets oversatte titelGastric carcinoma is the most frequent Epstein-Barr virus-associated malignancy
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind175
Udgave nummer47A
ISSN0041-5782
StatusUdgivet - 18 nov. 2013
Udgivet eksterntJa

Emneord

  • Carcinoma/epidemiology
  • Epstein-Barr Virus Infections/complications
  • Herpesvirus 4, Human/genetics
  • Humans
  • Male
  • Stomach Neoplasms/epidemiology

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